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1دورية أكاديمية
المؤلفون: Markus T. Sainio, Tiina Rasila, Svetlana M. Molchanova, Julius Järvilehto, Rubén Torregrosa-Muñumer, Sandra Harjuhaahto, Jana Pennonen, Nadine Huber, Sanna-Kaisa Herukka, Annakaisa Haapasalo, Henrik Zetterberg, Tomi Taira, Johanna Palmio, Emil Ylikallio, Henna Tyynismaa
المصدر: Frontiers in Cell and Developmental Biology, Vol 9 (2022)
مصطلحات موضوعية: neurofilament light (NfL), motor neurodegeneration, axon, Charcot-Marie-Tooth (CMT) disease, induced pluripotent stem cells, motor neuron (MN), Biology (General), QH301-705.5
وصف الملف: electronic resource
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2دورية أكاديمية
المؤلفون: Sandra Harjuhaahto, Tiina S. Rasila, Svetlana M. Molchanova, Rosa Woldegebriel, Jouni Kvist, Svetlana Konovalova, Markus T. Sainio, Jana Pennonen, Rubén Torregrosa-Muñumer, Hazem Ibrahim, Timo Otonkoski, Tomi Taira, Emil Ylikallio, Henna Tyynismaa
المصدر: Neurobiology of Disease, Vol 141, Iss , Pp 104940- (2020)
مصطلحات موضوعية: CHCHD2, CHCHD10, Induced pluripotent stem cell, Motor neuron differentiation, CMT2, SMAJ, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571
وصف الملف: electronic resource
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المؤلفون: Jeremi J Turkia, Jouni Kvist, Nadine Huber, Ras Trokovic, Vivek Sharma, Markus T. Sainio, Annakaisa Haapasalo, Jana Pennonen, Henna Tyynismaa, Emil Ylikallio, Sanna-Kaisa Herukka, Mari Auranen, Erika Rannila, Marco Reidelbach, Rubén Torregrosa-Muñumer, Sebastian Kenvin
المساهمون: STEMM - Stem Cells and Metabolism Research Program, Department of Physics, Centre of Excellence in Stem Cell Metabolism, Medicum, HUS Neurocenter, Clinicum, Neurologian yksikkö, Research Programs Unit, Institute of Biotechnology, Materials Physics, Helsinki Institute of Life Science HiLIFE, Department of Medical and Clinical Genetics, Henna Tyynismaa / Principal Investigator, Neuroscience Center
مصطلحات موضوعية: Mitochondrial DNA, Protein subunit, Mutant, dna, medicine.disease_cause, DNA, Mitochondrial, 03 medical and health sciences, Adenosine Triphosphate, 0302 clinical medicine, Genetics, medicine, Humans, motor neurons, heteroplasmy, Molecular Biology, Genetics (clinical), 030304 developmental biology, 0303 health sciences, Mutation, biology, ATP synthase, Neurogenesis, General Medicine, Mitochondrial Proton-Translocating ATPases, mitochondrial, Heteroplasmy, Cell biology, MT-ATP6, biology.protein, Ataxia, 3111 Biomedicine, mutation, lactates, metabolism, 030217 neurology & neurosurgery
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2f50f541aa9661cc3bf7d89a952c14d
http://hdl.handle.net/10138/345126 -
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المؤلفون: Markus T, Sainio, Tiina, Rasila, Svetlana M, Molchanova, Julius, Järvilehto, Rubén, Torregrosa-Muñumer, Sandra, Harjuhaahto, Jana, Pennonen, Nadine, Huber, Sanna-Kaisa, Herukka, Annakaisa, Haapasalo, Henrik, Zetterberg, Tomi, Taira, Johanna, Palmio, Emil, Ylikallio, Henna, Tyynismaa
المصدر: Frontiers in cell and developmental biology. 9
URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::4e467564e71bf755d01fe6739005a578
https://pubmed.ncbi.nlm.nih.gov/35237613 -
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المساهمون: STEMM - Stem Cells and Metabolism Research Program, Research Programs Unit
مصطلحات موضوعية: Male, 0301 basic medicine, Aging, STRESS, Medicine (miscellaneous), Apoptosis, Pharmacology, Resveratrol, medicine.disease_cause, Antioxidants, chemistry.chemical_compound, 0302 clinical medicine, Stilbenes, Endothelial dysfunction, skin and connective tissue diseases, GENE-EXPRESSION, SIRT1 ACTIVATION, Nutrition and Dietetics, CARDIOVASCULAR HEALTH, biology, food and beverages, Heart, 3. Good health, Nitric oxide synthase, FACTOR-KAPPA-B, medicine.symptom, 3143 Nutrition, CARDIAC DYSFUNCTION, Programmed cell death, 030209 endocrinology & metabolism, Inflammation, Oxidative phosphorylation, 03 medical and health sciences, TERM CALORIC RESTRICTION, Oxidation, medicine, Animals, NITRIC-OXIDE SYNTHASE, 030109 nutrition & dietetics, business.industry, medicine.disease, Rats, Oxidative Stress, chemistry, CELL-DEATH, Dietary Supplements, ENDOTHELIAL DYSFUNCTION, biology.protein, business, Oxidative stress
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e16baecd08d58d982d5f53efc6eb498
http://hdl.handle.net/10138/340114 -
6Peripheral neuropathy linked mRNA export factor GANP reshapes gene regulation in human motor neurons
المؤلفون: Jouni Kvist, Henna Tyynismaa, Jemeen Sreedharan, Sanna-Kaisa Herukka, Markus T. Sainio, Satu Hänninen, Annakaisa Haapasalo, Emil Ylikallio, Rosa Woldegebriel, Matthew White, Andrew R. Bassett, Sandra Harjuhaahto, Nadine Huber, Sinkko M, Olli Carpén, Rubén Torregrosa-Muñumer
مصطلحات موضوعية: Regulation of gene expression, 0303 health sciences, Messenger RNA, Motor neuron, Biology, Cell biology, 03 medical and health sciences, 0302 clinical medicine, medicine.anatomical_structure, nervous system, RNA splicing, Protein biosynthesis, medicine, MRNA transport, Nuclear export signal, Gene, 030217 neurology & neurosurgery, 030304 developmental biology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::9c1ce0a7e31db46801d1220721d28531
https://doi.org/10.1101/2021.05.18.444636 -
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المؤلفون: Pooja Manjunath, Jouni Kvist, Sundar Baral, Reijo Käkelä, Jayasimman Rajendran, Rubén Torregrosa-Muñumer, Henna Tyynismaa, Yang Yang, Svetlana Konovalova, Xiaonan Liu, Minna Holopainen, Pentti Somerharju, Markku Varjosalo
مصطلحات موضوعية: Phosphatidylglycerol, 0303 health sciences, Phospholipid, Matrix (biology), Cell biology, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, chemistry, Cardiolipin, Prohibitin, Inner mitochondrial membrane, 030217 neurology & neurosurgery, Function (biology), Homeostasis, 030304 developmental biology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::5f76effa148a3c02833c3b6e140819b1
https://doi.org/10.1101/2021.01.03.424667 -
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المؤلفون: Jana Pennonen, Markus T. Sainio, Svetlana M. Molchanova, Sandra Harjuhaahto, Jouni Kvist, Henna Tyynismaa, Tomi Taira, Emil Ylikallio, Hazem Ibrahim, Tiina S Rasila, Timo Otonkoski, Rubén Torregrosa-Muñumer, Svetlana Konovalova, Rosa Woldegebriel
المساهمون: Research Programs Unit, STEMM - Stem Cells and Metabolism Research Program, Faculty of Medicine, University of Helsinki, Molecular and Integrative Biosciences Research Programme, Faculty of Biological and Environmental Sciences, Centre of Excellence in Stem Cell Metabolism, Henna Tyynismaa / Principal Investigator, Helsinki One Health (HOH), HUS Children and Adolescents, Timo Pyry Juhani Otonkoski / Principal Investigator, Synaptic Plasticity and Neuronal Synchronization, Veterinary Biosciences, Tomi Taira / Principal Investigator, Neuroscience Center, Clinicum, HUS Neurocenter, Department of Neurosciences, Neurologian yksikkö, Helsinki University Hospital Area, Department of Medical and Clinical Genetics, Staff Services, Helsinki Institute of Life Science HiLIFE, Basal ganglia circuits
المصدر: Neurobiology of Disease, Vol 141, Iss, Pp 104940-(2020)
مصطلحات موضوعية: 0301 basic medicine, Parkinson's disease, POTENTIATION, ENERGY-METABOLISM, Mitochondrion, AMYOTROPHIC-LATERAL-SCLEROSIS, 3124 Neurology and psychiatry, Membrane Potentials, GLUTAMATE, 0302 clinical medicine, Amyotrophic lateral sclerosis, Induced pluripotent stem cell, Motor Neurons, CMT2, Glutamate receptor, Long-term potentiation, Cell Differentiation, Parkinson Disease, RNA sequencing, Mitochondria, DNA-Binding Proteins, RECEPTORS, medicine.anatomical_structure, Neurology, PLURIPOTENT STEM-CELLS, CHCHD2, Induced Pluripotent Stem Cells, DPP6, Biology, lcsh:RC321-571, Mitochondrial Proteins, 03 medical and health sciences, medicine, Humans, lcsh:Neurosciences. Biological psychiatry. Neuropsychiatry, CRISPR/Cas9, RELEASE, MUTATIONS, Amyotrophic Lateral Sclerosis, Motor neuron differentiation, 3112 Neurosciences, Spinal muscular atrophy, Motor neuron, medicine.disease, 030104 developmental biology, CHCHD10, SMAJ, Synapses, ALS, Transcriptome, Neuroscience, 030217 neurology & neurosurgery, Transcription Factors
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::191057f2ef982386dd6e451124a5528c
http://hdl.handle.net/10138/317778 -
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المؤلفون: Luis Blanco, Annika Pfeiffer, Sjoerd Wanrooij, Gorazd Stojkovič, Josefin M. E. Forslund, Natalie Al-Furoukh, Jaakko L. O. Pohjoismäki, Steffi Goffart, Gustavo Carvalho, Rubén Torregrosa-Muñumer
المصدر: Proceedings of the National Academy of Sciences. 114:11398-11403
مصطلحات موضوعية: DNA Replication, 0301 basic medicine, Mitochondrial DNA, Pyridines, Ultraviolet Rays, DNA repair, DNA-Directed DNA Polymerase, Mitochondrion, DNA, Mitochondrial, Cell Line, Mice, 03 medical and health sciences, 0302 clinical medicine, Animals, Cells, Cultured, Polymerase, Genetics, Multidisciplinary, biology, Fibroblasts, Biological Sciences, D-loop replication, Replication (computing), Culture Media, 030104 developmental biology, biology.protein, Primase, Gene Deletion, 030217 neurology & neurosurgery, MtDNA replication
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27e75be860438784b1a8895f41fb3c43
https://doi.org/10.1073/pnas.1705367114 -
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المؤلفون: Julia Döhla, Emilia Kuuluvainen, Nadja Gebert, Ana Amaral, Johanna I. Englund, Swetha Gopalakrishnan, Svetlana Konovalova, Anni I. Nieminen, Ella S. Salminen, Rubén Torregrosa Muñumer, Kati Ahlqvist, Yang Yang, Hien Bui, Timo Otonkoski, Reijo Käkelä, Ville Hietakangas, Henna Tyynismaa, Alessandro Ori, Pekka Katajisto
المصدر: Nature cell biology. 24(2)
مصطلحات موضوعية: Proteome, Cell Differentiation, Mice, Transgenic, Cell Biology, DNA, Mitochondrial, Cell Line, Mitochondria, Mice, Inbred C57BL, Adult Stem Cells, Genes, Mitochondrial, Phenotype, Metabolome, Animals, Humans, Cell Lineage, Female, Energy Metabolism, Mammary Glands, Human, Cellular Senescence, Cell Proliferation