المؤلفون: Jang, KJ, Otieno, MA, Ronxhi, J, Lim, HK, Ewart, L, Kodella, KR, Petropolis, DB, Kulkarni, G, Rubins, JE, Conegliano, D, Nawroth, J, Simic, D, Lam, W, Singer, M, Barale, E, Singh, B, Sonee, M, Streeter, AJ, Manthey, C, Jones, B, Srivastava, A, Andersson, LC, Williams, D, Park, H, Barrile, R, Sliz, J, Herland, A, Haney, S, Karalis, K, Ingber, DE, Hamilton, GA

المصدر: Science translational medicine. 11(517)

مصطلحات موضوعية: Medicin och hälsovetenskap

URL الوصول: http://kipublications.ki.se/Default.aspx?queryparsed=id:142261281

المؤلفون: Kroll KT; Harvard University, Paulson School of Engineering and Applied Sciences, Cambridge, MA, United States of America.; Wyss Institute for Biologically Inspired Engineering, Boston, MA, United States of America.; Complex in vitro Systems, Safety Assessment, Genentech Inc, South San Francisco, CA, United States of America., Homan KA; Complex in vitro Systems, Safety Assessment, Genentech Inc, South San Francisco, CA, United States of America., Uzel SGM; Harvard University, Paulson School of Engineering and Applied Sciences, Cambridge, MA, United States of America.; Wyss Institute for Biologically Inspired Engineering, Boston, MA, United States of America., Mata MM; Harvard University, Paulson School of Engineering and Applied Sciences, Cambridge, MA, United States of America.; Wyss Institute for Biologically Inspired Engineering, Boston, MA, United States of America., Wolf KJ; Harvard University, Paulson School of Engineering and Applied Sciences, Cambridge, MA, United States of America.; Wyss Institute for Biologically Inspired Engineering, Boston, MA, United States of America., Rubins JE; Harvard University, Paulson School of Engineering and Applied Sciences, Cambridge, MA, United States of America.; Wyss Institute for Biologically Inspired Engineering, Boston, MA, United States of America., Lewis JA; Harvard University, Paulson School of Engineering and Applied Sciences, Cambridge, MA, United States of America.; Wyss Institute for Biologically Inspired Engineering, Boston, MA, United States of America.; Harvard Stem Cell Institute, Cambridge, MA, United States of America.

المصدر: Biofabrication [Biofabrication] 2024 Jul 05; Vol. 16 (4). Date of Electronic Publication: 2024 Jul 05.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: IOP Pub Country of Publication: England NLM ID: 101521964 Publication Model: Electronic Cited Medium: Internet ISSN: 1758-5090 (Electronic) Linking ISSN: 17585082 NLM ISO Abbreviation: Biofabrication Subsets: MEDLINE

مواضيع طبية MeSH: Organoids*/cytology , Kidney*/cytology , Kidney*/blood supply , Human Umbilical Vein Endothelial Cells* , Perfusion*, Humans ; Lab-On-A-Chip Devices ; Animals ; Tissue Engineering/methods ; Extracellular Matrix/metabolism

المؤلفون: Foster AJ; Drug Safety and Metabolism, AstraZeneca IMED Biotech Unit, Cambridge, CB4 0WG, UK. alison.foster2@astraeneca.com., Chouhan B; Drug Safety and Metabolism, AstraZeneca IMED Biotech Unit, Gothenburg, 431 83, Sweden., Regan SL; Drug Safety and Metabolism, AstraZeneca IMED Biotech Unit, Cambridge, CB4 0WG, UK., Rollison H; Drug Safety and Metabolism, AstraZeneca IMED Biotech Unit, Cambridge, CB4 0WG, UK., Amberntsson S; Drug Safety and Metabolism, AstraZeneca IMED Biotech Unit, Gothenburg, 431 83, Sweden., Andersson LC; Drug Safety and Metabolism, AstraZeneca IMED Biotech Unit, Gothenburg, 431 83, Sweden., Srivastava A; Drug Safety and Metabolism, AstraZeneca IMED Biotech Unit, Cambridge, CB4 0WG, UK., Darnell M; Drug Safety and Metabolism, AstraZeneca IMED Biotech Unit, Gothenburg, 431 83, Sweden., Cairns J; Discovery Sciences, AstraZeneca IMED Biotech Unit, Cambridge, UK., Lazic SE; Discovery Sciences, AstraZeneca IMED Biotech Unit, Cambridge, UK., Jang KJ; Emulate, Inc, 27, Drydock Ave, 02210, Boston, MA, US., Petropolis DB; Emulate, Inc, 27, Drydock Ave, 02210, Boston, MA, US., Kodella K; Emulate, Inc, 27, Drydock Ave, 02210, Boston, MA, US., Rubins JE; Emulate, Inc, 27, Drydock Ave, 02210, Boston, MA, US., Williams D; Drug Safety and Metabolism, AstraZeneca IMED Biotech Unit, Cambridge, CB4 0WG, UK., Hamilton GA; Emulate, Inc, 27, Drydock Ave, 02210, Boston, MA, US., Ewart L; Drug Safety and Metabolism, AstraZeneca IMED Biotech Unit, Cambridge, CB4 0WG, UK., Morgan P; Drug Safety and Metabolism, AstraZeneca IMED Biotech Unit, Cambridge, CB4 0WG, UK.

المصدر: Archives of toxicology [Arch Toxicol] 2019 Apr; Vol. 93 (4), pp. 1021-1037. Date of Electronic Publication: 2019 Mar 26.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 0417615 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-0738 (Electronic) Linking ISSN: 03405761 NLM ISO Abbreviation: Arch Toxicol Subsets: MEDLINE

مواضيع طبية MeSH: Models, Biological*, Chemical and Drug Induced Liver Injury/*metabolism , Hepatocytes/*drug effects , Liver/*drug effects , Spheroids, Cellular/*drug effects, Acetaminophen/toxicity ; Arabinofuranosyluracil/analogs & derivatives ; Arabinofuranosyluracil/toxicity ; Biomarkers/metabolism ; Cell Culture Techniques ; Cell Survival/drug effects ; Dose-Response Relationship, Drug ; Glutathione Transferase/metabolism ; Hepatocytes/metabolism ; Humans ; Liver/metabolism ; Spheroids, Cellular/metabolism

المؤلفون: Peel S; AstraZeneca IMED Biotech Unit, Discovery Sciences, Cambridge, UK. Samantha.Peel@astrazeneca.com., Corrigan AM, Ehrhardt B, Jang KJ, Caetano-Pinto P, Boeckeler M, Rubins JE, Kodella K, Petropolis DB, Ronxhi J, Kulkarni G, Foster AJ, Williams D, Hamilton GA, Ewart L

المصدر: Lab on a chip [Lab Chip] 2019 Jan 29; Vol. 19 (3), pp. 410-421.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 101128948 Publication Model: Print Cited Medium: Internet ISSN: 1473-0189 (Electronic) Linking ISSN: 14730189 NLM ISO Abbreviation: Lab Chip

مواضيع طبية MeSH: Lab-On-A-Chip Devices*, Optical Imaging/*instrumentation, Animals ; Automation ; Drug Evaluation, Preclinical ; Humans ; Kidney/diagnostic imaging ; Kidney/drug effects ; Liver/diagnostic imaging ; Liver/drug effects ; Rats

المؤلفون: Leggett SE; Center for Biomedical Engineering, School of Engineering, Providence, RI 02912, USA and Pathobiology Graduate Program Brown University, Providence, RI 02912, USA. ian_wong@brown.edu., Sim JY; Center for Biomedical Engineering, School of Engineering, Providence, RI 02912, USA., Rubins JE; Center for Biomedical Engineering, School of Engineering, Providence, RI 02912, USA., Neronha ZJ; Center for Biomedical Engineering, School of Engineering, Providence, RI 02912, USA., Williams EK; Center for Biomedical Engineering, School of Engineering, Providence, RI 02912, USA., Wong IY; Center for Biomedical Engineering, School of Engineering, Providence, RI 02912, USA and Pathobiology Graduate Program Brown University, Providence, RI 02912, USA. ian_wong@brown.edu.

المصدر: Integrative biology : quantitative biosciences from nano to macro [Integr Biol (Camb)] 2016 Nov 07; Vol. 8 (11), pp. 1133-1144.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Oxford University Press Country of Publication: England NLM ID: 101478378 Publication Model: Print Cited Medium: Internet ISSN: 1757-9708 (Electronic) Linking ISSN: 17579694 NLM ISO Abbreviation: Integr Biol (Camb) Subsets: MEDLINE

مواضيع طبية MeSH: Models, Statistical*, Epithelial Cells/*cytology , Epithelial Cells/*metabolism , Epithelial-Mesenchymal Transition/*physiology , High-Throughput Screening Assays/*methods , Mesoderm/*cytology , Mesoderm/*metabolism, Cell Line ; Cell Size ; Computer Simulation ; Humans ; Models, Biological ; Normal Distribution