المؤلفون: Lisa M. Plitnick, Beth Hutchins, Sheri Dubey, Nianyu Li, Rupesh P. Amin, Stephanie Born, Ruban Mangadu, Joseph H. Phillips, Venkataraman Sriram, Danuta J. Herzyk

المصدر: Journal of Immunotoxicology, Vol 17, Iss 1, Pp 175-185 (2020)

مصطلحات موضوعية: anti-pd-1, vaccination, murine, alternate model, Immunologic diseases. Allergy, RC581-607, Toxicology. Poisons, RA1190-1270

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1547-691X; https://doaj.org/toc/1547-6901

URL الوصول: https://doaj.org/article/2b47def718a34f4fad7a7bc77b84c7e9

المؤلفون: Mihirbaran Mandal, Maria Madeira, Rupesh P. Amin, Alexei V. Buevich, Alan Cheng, Marc Labroli, Xiaoxiang Liu, John Acton, Barbara Pio, Andrea Basso, Harry Chobanian, Grace Dong, Jamie Dropinski, Yan Guo, Zhuyan Guo, Stan Kurowski, Walter Korfmacher, Sandra Lee, Dongfang Meng, Debra Ondeyka, Zhiqiang Yang, Rumin Zhang, Huijun Wei, Zhicai Wu, Fengqi Zhang, Gordon Wollenberg, Tesfaye Biftu, William J. Greenlee, Madhu Chintala, Milana Maletic, Zhaoning Zhu

المصدر: Journal of Medicinal Chemistry. 65:5575-5592

مصطلحات موضوعية: Lactones, Receptors, Proteinase-Activated, Drug Discovery, Myocardial Infarction, Animals, Humans, Molecular Medicine, Receptor, PAR-1, Thrombosis, Platelet Aggregation Inhibitors, Rats

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20d0e58362d38a85e8d5aef1a3cbe66a
https://doi.org/10.1021/acs.jmedchem.1c02048

المؤلفون: Gregory L. Adams, Parul S. Pall, Steven M. Grauer, Xiaoping Zhou, Jeanine E. Ballard, Marissa Vavrek, Richard L. Kraus, Pierre Morissette, Nianyu Li, Stefania Colarusso, Elisabetta Bianchi, Anandan Palani, Rebecca Klein, Christopher T. John, Deping Wang, Matthew Tudor, Andrew F. Nolting, Mirlinda Biba, Timothy Nowak, Alexey A. Makarov, Mikhail Reibarkh, Alexei V. Buevich, Wendy Zhong, Erik L. Regalado, Xiao Wang, Qi Gao, Aurash Shahripour, Yuping Zhu, Daniele de Simone, Tommaso Frattarelli, Nicolo’ Maria Pasquini, Paola Magotti, Roberto Iaccarino, Yuxing Li, Kelli Solly, Keun-Joong Lee, Weixun Wang, Feifei Chen, Haoyu Zeng, Jixin Wang, Hilary Regan, Rupesh P. Amin, Christopher P. Regan, Christopher S. Burgey, Darrell A. Henze, Chengzao Sun, David M. Tellers

المصدر: Journal of Medicinal Chemistry. 65:485-496

مصطلحات موضوعية: Drug Discovery, Molecular Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::6ecd04283fe1d38ba43c9ca77818a20e
https://doi.org/10.1021/acs.jmedchem.1c01570

المؤلفون: Thomas J. Tucker, Nianyu Li, Scott P. Salowe, Harold B. Wood, Danila Branca, Alan S. Bass, Rupesh P. Amin, BethAnn Murphy, Aurash Shahripour, Angela Kerekes, Abbas Walji, Nicole Buist, Jeffrey T. Kuethe, Huaibing He, Rodger Tracy, Kenneth A. Koeplinger, Weixun Wang, Bhavana Bhatt, Candice Alleyne, Sookhee Ha, Douglas G. Johns, Elisabetta Bianchi, Chengwei Wu, Peter Orth, Tjerk Bueters, Yusheng Xiong, Hratch J. Zokian, Michael J. Hafey, Mark W. Embrey, John Higgins

المصدر: Journal of Medicinal Chemistry. 64:16770-16800

مصطلحات موضوعية: chemistry.chemical_classification, Molecular Structure, biology, PCSK9, PCSK9 Inhibitors, Administration, Oral, Biological Availability, Peptide, Pharmacology, Crystallography, X-Ray, Proprotein convertase, Peptides, Cyclic, Rats, Bioavailability, Macaca fascicularis, Structure-Activity Relationship, chemistry, Drug Discovery, biology.protein, Animals, Molecular Medicine, Kexin, Dosing, Antibody, Tricyclic

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d01cd83054fdae5294b50a6dbca9f594
https://doi.org/10.1021/acs.jmedchem.1c01599

المؤلفون: Robert O. Blaustein, Georgy Hartmann, Guiquan Liu, Dennis Leung, Beth Ann Murphy, Sriram Tyagarajan, Yingju Xu, Zhijian Lu, Jian Liu, Louis-Charles Campeau, Sheng-Ping Wang, Daniel Metzger, Joseph L. Duffy, Qinghao Chen, Josee Cote, Rupesh P. Amin, Debra Ondeyka, Jianming Bao, Wanying Sun, Yi-Heng Chen, Peter J. Sinclair, Concetta Lipardi, Feng Ye, Douglas G. Johns, Katipally Revathi Reddy, Petr Vachal, Kaushik Mitra, Gordon K. Wollenberg, Shao Pengcheng Patrick, Kake Zhao, Lushi Tan

المصدر: Journal of Medicinal Chemistry. 64:13215-13258

مصطلحات موضوعية: Statin, medicine.drug_class, Coronary Disease, Pharmacology, Structure-Activity Relationship, chemistry.chemical_compound, Dogs, Anacetrapib, In vivo, Drug Discovery, Cholesterylester transfer protein, medicine, Animals, Humans, Rats, Wistar, Adverse effect, CETP inhibitor, Oxazolidinones, Molecular Structure, biology, Chemistry, Drug discovery, Anticholesteremic Agents, Macaca mulatta, Cholesterol Ester Transfer Proteins, Mice, Inbred C57BL, biology.protein, Molecular Medicine, lipids (amino acids, peptides, and proteins), Lipoprotein

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::573c5ff3dfab385ab49a4f550abe8129
https://doi.org/10.1021/acs.jmedchem.1c00959

المؤلفون: Yi-Zhong Gu, Katerina Vlasakova, Glen Miller, Nicholas T. Gatto, Paul J. Ciaccio, Sabu Kuruvilla, Elizabeth G. Besteman, Roger Smith, Spencer J. Reynolds, Rupesh P. Amin, Warren E. Glaab, Gordon Wollenberg, Jose Lebron, Frank D. Sistare

المصدر: Toxicologic Pathology. :019262332311628

مصطلحات موضوعية: Cell Biology, Toxicology, Molecular Biology, Pathology and Forensic Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::ca81b65118f034c663e621457909c3ff
https://doi.org/10.1177/01926233231162809

المؤلفون: Bhavana Bhatt, Frank D. Sistare, Kiran Palyada, Feifei Chen, Isabelle Bourgeois, Christopher Brynczka, Rupesh P. Amin, Katerina Vlasakova, José A. Lebrón, Roger Smith, Kenneth A. Koeplinger, Kenneth D Anderson, Kathleen Cox, Robert Houle, Warren E. Glaab, Yi-Zhong Gu, Xiaoyan Chu

المصدر: Toxicological Sciences. 172:155-166

مصطلحات موضوعية: PEG 400, Kidney, Organic cation transport proteins, biology, Organic anion transporter 1, 02 engineering and technology, Polyethylene glycol, Prodrug, Pharmacology, 021001 nanoscience & nanotechnology, Toxicology, 030226 pharmacology & pharmacy, Nephrotoxicity, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, medicine.anatomical_structure, chemistry, PEG ratio, biology.protein, medicine, 0210 nano-technology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a7c8a93f2d09b4d982560ba5c94462b
https://doi.org/10.1093/toxsci/kfz186

المؤلفون: Shashi Amur, Rupesh P. Amin, Katerina Vlasakova, Sean P. Troth, Warren E. Glaab

المصدر: Seminars in Nephrology. 39:202-214

مصطلحات موضوعية: 0301 basic medicine, medicine.medical_specialty, business.industry, 030232 urology & nephrology, Acute kidney injury, Acute Kidney Injury, Kidney Function Tests, medicine.disease, Pre-clinical development, Translational Research, Biomedical, Clinical trial, MicroRNAs, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Nephrology, medicine, Kidney injury, Humans, Biomarker (medicine), Intensive care medicine, business, Early phase, Clinical evaluation, Biomarkers

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::963639c19be732c6ce807d060d2193e7
https://doi.org/10.1016/j.semnephrol.2018.12.008

المؤلفون: Stephanie Born, Lisa M. Plitnick, Ruban Mangadu, Danuta J. Herzyk, Venkataraman Sriram, Sheri Dubey, Joseph H. Phillips, Beth Hutchins, Rupesh P. Amin, Nianyu Li

المصدر: Journal of Immunotoxicology, Vol 17, Iss 1, Pp 175-185 (2020)

مصطلحات موضوعية: alternate model, animal diseases, T-Lymphocytes, Programmed Cell Death 1 Receptor, 010501 environmental sciences, Toxicology, 01 natural sciences, Mice, Antineoplastic Agents, Immunological, Programmed cell death 1, 0303 health sciences, biology, Vaccination, Hepatitis B, medicine.anatomical_structure, Colonic Neoplasms, Anti-PD-1 Monoclonal Antibody, lcsh:Immunologic diseases. Allergy, Primates, Hepatitis B virus, T cell, Immunology, chemical and pharmacologic phenomena, Adenocarcinoma, Antibodies, Monoclonal, Humanized, 03 medical and health sciences, lcsh:RA1190-1270, medicine, Animals, Humans, Hepatitis B Vaccines, lcsh:Toxicology. Poisons, 030304 developmental biology, 0105 earth and related environmental sciences, Tumor microenvironment, murine, Non human primate, business.industry, anti-pd-1, biochemical phenomena, metabolism, and nutrition, Immune checkpoint, Rats, Mice, Inbred C57BL, Antibody response, Antibody Formation, biology.protein, Cancer research, bacteria, lcsh:RC581-607, business, Immunologic Memory

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44255ab09c7973f511f37d6dc86ef003
https://pubmed.ncbi.nlm.nih.gov/33078980

المؤلفون: Pierre R. Bushel, Stella O. Sieber, Leping Li, Kristina G. Flores, Rupesh P. Amin, Cynthia L. Innes, Lee Bennett, Rodney E. Shackelford, Alexandra N. Heinloth, Richard S. Paules

المصدر: Radiation Research. 160:273-290

مصطلحات موضوعية: G2 Phase, DNA, Complementary, Cell cycle checkpoint, Transcription, Genetic, Ultraviolet Rays, DNA damage, Biophysics, Down-Regulation, Cell Cycle Proteins, Ataxia Telangiectasia Mutated Proteins, Protein Serine-Threonine Kinases, Biology, medicine.disease_cause, Models, Biological, Cell Line, S Phase, Histones, Cyclin E, Gene expression, medicine, Humans, Radiology, Nuclear Medicine and imaging, Kinase activity, Cells, Cultured, Oligonucleotide Array Sequence Analysis, Expressed Sequence Tags, Regulation of gene expression, Radiation, Reverse Transcriptase Polymerase Chain Reaction, Tumor Suppressor Proteins, G1 Phase, Fibroblasts, medicine.disease, Molecular biology, Up-Regulation, DNA-Binding Proteins, Oxidative Stress, Gene Expression Regulation, Gamma Rays, Multigene Family, Ataxia-telangiectasia, RNA, Tumor Suppressor Protein p53, Algorithms, Oxidative stress, DNA Damage, Transcription Factors

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd73ef9922f19c5215a19581c56988ec
https://doi.org/10.1667/rr3047