المؤلفون: Rute A Tomaz, Ekaterini D Zacharis, Fabian Bachinger, Annabelle Wurmser, Daniel Yamamoto, Sandra Petrus-Reurer, Carola M Morell, Dominika Dziedzicka, Brandon T Wesley, Imbisaat Geti, Charis-Patricia Segeritz, Miguel C de Brito, Mariya Chhatriwala, Daniel Ortmann, Kourosh Saeb-Parsy, Ludovic Vallier

المصدر: eLife, Vol 11 (2022)

مصطلحات موضوعية: forward programming, hepatocytes, pluripotent stem cells, Medicine, Science, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://elifesciences.org/articles/71591; https://doaj.org/toc/2050-084X

URL الوصول: https://doaj.org/article/07a94c8ea33a4c4d9ca24e8d7b3c1339

المؤلفون: Emma Bell, Edward W. Curry, Wout Megchelenbrink, Luc Jouneau, Vincent Brochard, Rute A. Tomaz, King Hang T. Mau, Yaser Atlasi, Roshni A. de Souza, Hendrik Marks, Hendrik G. Stunnenberg, Alice Jouneau, Véronique Azuara

المصدر: Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)

مصطلحات موضوعية: Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2041-1723

URL الوصول: https://doaj.org/article/5299ca445e9743b2869fc3fe2a1a17ce

المؤلفون: Brandon T. Wesley, Alexander D. B. Ross, Daniele Muraro, Zhichao Miao, Sarah Saxton, Rute A. Tomaz, Carola M. Morell, Katherine Ridley, Ekaterini D. Zacharis, Sandra Petrus-Reurer, Judith Kraiczy, Krishnaa T. Mahbubani, Stephanie Brown, Jose Garcia-Bernardo, Clara Alsinet, Daniel Gaffney, Dave Horsfall, Olivia C. Tysoe, Rachel A. Botting, Emily Stephenson, Dorin-Mirel Popescu, Sonya MacParland, Gary Bader, Ian D. McGilvray, Daniel Ortmann, Fotios Sampaziotis, Kourosh Saeb-Parsy, Muzlifah Haniffa, Kelly R. Stevens, Matthias Zilbauer, Sarah A. Teichmann, Ludovic Vallier

المصدر: Nature Cell Biology. 24:1487-1498

مصطلحات موضوعية: Organoids, Liver, Hepatocytes, Humans, Cell Differentiation, Cell Biology, Transcription Factors

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2f2e9ea02987281a5813a196e29654f
https://doi.org/10.1038/s41556-022-00989-7

المؤلفون: Rute A. Tomaz, Ekaterini D. Zacharis, Fabian Bachinger, Annabelle Wurmser, Daniel Yamamoto, Sandra Petrus-Reurer, Carola M. Morell, Dominika Dziedzicka, Brandon T. Wesley, Imbisaat Geti, Charis-Patricia Segeritz, Miguel Cardoso de Brito, Mariya Chhatriwala, Daniel Ortmann, Kourosh Saeb-Parsy, Ludovic Vallier

المساهمون: Tomaz, Rute A [0000-0002-9377-1431], Vallier, Ludovic [0000-0002-3848-2602], Apollo - University of Cambridge Repository

مصطلحات موضوعية: General Immunology and Microbiology, General Neuroscience, Induced Pluripotent Stem Cells, regenerative medicine, Receptors, Cytoplasmic and Nuclear, Cell Differentiation, General Medicine, Stem Cells and Regenerative Medicine, General Biochemistry, Genetics and Molecular Biology, Tools and Resources, Liver, stem cells, Humans, hepatocytes, pluripotent stem cells, forward programming, Human

وصف الملف: application/pdf; application/zip; text/xml

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e023f6edb4361b6326f9a402df618911

المؤلفون: Rute A Tomaz, Ekaterini D Zacharis, Fabian Bachinger, Annabelle Wurmser, Daniel Yamamoto, Sandra Petrus-Reurer, Carola M Morell, Dominika Dziedzicka, Brandon T Wesley, Imbisaat Geti, Charis-Patricia Segeritz, Miguel C de Brito, Mariya Chhatriwala, Daniel Ortmann, Kourosh Saeb-Parsy, Ludovic Vallier

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::28facff8441c30120a332f8a8b75df26
https://doi.org/10.7554/elife.71591.sa2

المؤلفون: Ludovic Vallier, Rodrigo A. Grandy, Rute A. Tomaz

المساهمون: Vallier, Ludovic [0000-0002-3848-2602], Apollo - University of Cambridge Repository

المصدر: Annual Review of Pathology: Mechanisms of Disease

مصطلحات موضوعية: 0301 basic medicine, Cellular differentiation, Induced Pluripotent Stem Cells, Computational biology, Disease, Biology, liver, Models, Biological, Pathology and Forensic Medicine, 03 medical and health sciences, Liver disease, 0302 clinical medicine, disease modeling, medicine, Humans, Human Induced Pluripotent Stem Cells, Induced pluripotent stem cell, hiPSCs, reprogramming, Cell Differentiation, differentiation, medicine.disease, Model disease, 3. Good health, 030104 developmental biology, Hepatocytes, Reprogramming, 030217 neurology & neurosurgery

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da29db177b1069dae6376ba908a41015
https://doi.org/10.1146/annurev-pathol-020117-043634

المؤلفون: Daniel Ortmann, Daniele Muraro, Laura G. Reinholdt, Brandon T Wesley, Ludovic Vallier, Daniel A. Skelly, Christopher L. Baker, Ted Choi, Yuanhua Huang, Peter J. Rugg-Gunn, Rute A. Tomaz, Steven C. Munger, Stephanie Brown, Anna Osnato, Gary A. Churchill, Anne Czechanski, Selcan Aydin, Oliver Stegle, Giovanni Canu

المساهمون: Osnato, Anna [0000-0001-5241-1512], Wesley, Brandon [0000-0003-0530-329X], Vallier, Ludovic [0000-0002-3848-2602], Apollo - University of Cambridge Repository

المصدر: Cell Stem Cell

مصطلحات موضوعية: Pluripotent Stem Cells, education, Cell, Induced Pluripotent Stem Cells, mouse embryonic stem cells, naïve, Biology, eQTL, 03 medical and health sciences, Mice, 0302 clinical medicine, Short Article, Genetic variation, medicine, Animals, genetics, ground state, Epigenetics, Induced pluripotent stem cell, health care economics and organizations, 030304 developmental biology, Genetics, 0303 health sciences, variability, Wnt signaling pathway, Genetic Variation, Reproducibility of Results, Cell Differentiation, Cell Biology, differentiation, Phenotype, medicine.anatomical_structure, Biological Variation, Population, Expression quantitative trait loci, Molecular Medicine, Stem cell, signaling, 030217 neurology & neurosurgery

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d88e736e49dc0b59182dc8b3ba295dec

المؤلفون: Edward Curry, Véronique Azuara, King Hang T. Mau, Roshni A. de Souza, Vincent Brochard, Alice Jouneau, Rute A. Tomaz, Luc Jouneau, Wout Megchelenbrink, Emma Bell, Hendrik Marks, Yaser Atlasi, Hendrik G. Stunnenberg

المساهمون: Bell, Emma [0000-0003-4103-3741], Tomaz, Rute A [0000-0002-9377-1431], Marks, Hendrik [0000-0002-4198-3731], Stunnenberg, Hendrik G [0000-0002-0066-1576], Azuara, Véronique [0000-0003-4608-3713], Apollo - University of Cambridge Repository, Biologie du développement et reproduction (BDR), École nationale vétérinaire d'Alfort (ENVA)-Institut National de la Recherche Agronomique (INRA)-Centre National de la Recherche Scientifique (CNRS), Imperial College London, Radboud Institute for Molecular Life Sciences (RIMLS), Unité de recherche Virologie et Immunologie Moléculaires (VIM), Institut National de la Recherche Agronomique (INRA), Medical Research Council (MRC), Genesis Research Trust, The Portuguese Science & Technology foundation (FCT), Hammersmith Hospital, Faculty of Medicine and Health, Institute of Reproductive Sciences (IRS), Imperial College, London, Princess Máxima Center for Pediatric Oncology, Centre for Molecular Oncology, Department of Precision Medicine, Università della Campania Luigi Vanvitelli, Université Paris Saclay (COMUE), Institute of Reproductive and Developmental Biology, Faculty of Medicine, Department of Molecular Biology, Princeton University, Faculty of Health, Medicine and Life Sciences, Biologie de la Reproduction, Environnement, Epigénétique & Développement (BREED), École nationale vétérinaire d'Alfort (ENVA)-Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Université Paris-Saclay-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Biologie du Développement et Reproduction (BDR), École nationale vétérinaire d'Alfort (ENVA)-Institut National de la Recherche Agronomique (INRA), Unité de recherche Virologie et Immunologie Moléculaires (VIM (UR 0892)), French Society for Stem Cell Research. Corbeil-Essonne, FRA., Bell, E., Curry, E. W., Megchelenbrink, W., Jouneau, L., Brochard, V., Tomaz, R. A., Mau, K. H. T., Atlasi, Y., de Souza, R. A., Marks, H., Stunnenberg, H. G., Jouneau, A., Azuara, V., Jouneau, Alice, Azuara, Véronique, ProdInra, Archive Ouverte

المصدر: 3rd Annual Meeting
3rd Annual Meeting, Nov 2019, Lyon, France
Nature Communications
Nature Communications, Nature Publishing Group, 2020, 11 (1), ⟨10.1038/s41467-020-14916-7⟩
www.nature.com
3rd Annual Meeting, French Society for Stem Cell Research. Corbeil-Essonne, FRA., Nov 2019, Lyon, France
Nature Communications, 11, 1
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Nature Communications, 11
Nature Communications 1 (11), . (2020)

مصطلحات موضوعية: 0301 basic medicine, CHROMATIN, Transcription, Genetic, [SDV]Life Sciences [q-bio], General Physics and Astronomy, Stem cells, Mice, 0302 clinical medicine, BINDING, MEDIATOR, lcsh:Science, méthylation, Induced pluripotent stem cell, [SDV.BDD]Life Sciences [q-bio]/Development Biology, Regulation of gene expression, Multidisciplinary, Mediator Complex, Gene Expression Regulation, Developmental, Mouse Embryonic Stem Cells, Cell biology, Chromatin, Multidisciplinary Sciences, TRANSCRIPTION FACTORS, Enhancer Elements, Genetic, CpG site, Receptors, Estrogen, GROUND-STATE, DNA methylation, embryonic structures, Science & Technology - Other Topics, RNA Polymerase II, TRANSITION, Germ Layers, Protein Binding, musculoskeletal diseases, Pluripotent Stem Cells, Embryonic stem cells, Science, education, chemical and pharmacologic phenomena, Biology, Article, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, [SDV.BDD] Life Sciences [q-bio]/Development Biology, Developmental biology, parasitic diseases, pluripotence, Animals, enhancer, facteur de transcription, natural sciences, Enhancer, Molecular Biology, Science & Technology, General Chemistry, DNA Methylation, pluripotency, Embryonic stem cell, GENE, 030104 developmental biology, nervous system, Epiblast, IDENTITY, lcsh:Q, CpG Islands, EMBRYONIC STEM-CELLS, 030217 neurology & neurosurgery

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::046c04223cda3855ff63c5fe907d1490
https://www.repository.cam.ac.uk/handle/1810/304967

المؤلفون: David B. Savage, Antonio Vidal-Puig, Heather P. Harding, Sergio Rodriguez-Cuenca, Fiona M. Gribble, Naveed Sattar, John Tadross, Pranali Taskar, Emily L. Miedzybrodzka, Sam Virtue, Ming Yang, Y. C. Loraine Tung, Irene Cimino, Anthony P. Coll, Stephen O'Rahilly, Audrey Melvin, K. Sreekumaran Nair, Bernard B. Allan, Giles S.H. Yeo, Deborah A. Goldspink, David Ron, Jeffrey T.-J. Huang, Rute A. Tomaz, David Preiss, Satish Patel, Paul Welsh, Adam R. Konopka, Michael Chen, Frank Reimann, Ludovic Vallier, Raul Ruiz Esponda, Nicholas J. Wareham, Debra Rimmington

المساهمون: Coll, Anthony [0000-0003-2594-7463], Tadross, John A [0000-0002-8424-1252], Cimino, Irene [0000-0003-1397-5408], Rodriguez-Cuenca, Sergio [0000-0001-9635-0504], Harding, Heather [0000-0002-7359-7974], Yeo, Giles [0000-0001-8823-3615], Vidal-Puig, Antonio [0000-0003-4220-9577], Vallier, Ludovic [0000-0002-3848-2602], Wareham, Nicholas [0000-0003-1422-2993], Ron, David [0000-0002-3014-5636], Gribble, Fiona [0000-0002-4232-2898], Reimann, Frank [0000-0001-9399-6377], Savage, David [0000-0002-7857-7032], O'Rahilly, Stephen [0000-0003-2199-4449], Apollo - University of Cambridge Repository

المصدر: Nature

مصطلحات موضوعية: Blood Glucose, Male, 0301 basic medicine, endocrine system diseases, Administration, Oral, Mice, Obese, Type 2 diabetes, Mice, 0302 clinical medicine, Weight loss, Homeostasis, Medicine, Receptor, 2. Zero hunger, Multidisciplinary, digestive, oral, and skin physiology, Middle Aged, Metformin, 3. Good health, Intestines, Female, medicine.symptom, medicine.drug, Adult, medicine.medical_specialty, Glial Cell Line-Derived Neurotrophic Factor Receptors, Growth Differentiation Factor 15, 030209 endocrinology & metabolism, Peptide hormone, Diet, High-Fat, Article, 03 medical and health sciences, Double-Blind Method, Internal medicine, Weight Loss, Animals, Humans, Aged, business.industry, Body Weight, nutritional and metabolic diseases, medicine.disease, Enterocytes, 030104 developmental biology, Endocrinology, GDF15, Energy Intake, Energy Metabolism, business, Weight gain

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed7e813ae9add3737a91d92d4f91fd84
https://eprints.gla.ac.uk/207415/7/207415.pdf

المؤلفون: Matthias Zilbauer, Olivia C. Tysoe, Daniele Muraro, Ludovic Vallier, Carola M. Morell, Nicholas R.F. Hannan, Stuart J. Forbes, Samantha G. Tilson, Richard L. Gieseck, Thomas A. Wynn, Simone E. Adams, Rute A. Tomaz, Brandon T Wesley, Wei-Yu Lu, Judith Kraiczy, John R. Ferdinand, Kourosh Saeb-Parsy, Gabriel C. Oniscu, Alexander Ross, Casey A. Rimland, Francisco Otaizo-Carrasquero, Nikitas Georgakopoulos, Timothy G. Myers, Fotios Sampaziotis

المصدر: Hepatology
Rimland, C A, Tilson, S G, Morell, C M, Tomaz, R A, Lu, W-Y, Adams, S E, Georgakopoulos, N, Otaizo-Carrasquero, F, Myers, T G, Ferdinand, J R, Gieseck, R L, Sampaziotis, F, Tysoe, O C, Wesley, B, Muraro, D, Oniscu, G C, Hannan, N R, Forbes, S J, Saeb-Parsy, K, Wynn, T A & Vallier, L 2020, ' Regional differences in human biliary tissues and corresponding in vitro derived organoids ', Hepatology . https://doi.org/10.1002/hep.31252
Hepatology (Baltimore, Md.)

مصطلحات موضوعية: 0301 basic medicine, Tissue and Organ Procurement, Cellular differentiation, Intrahepatic bile ducts, Biology, Cholangiocyte, 03 medical and health sciences, Mice, 0302 clinical medicine, Liver Injury and Regeneration, Bile Ducts, Extrahepatic, Organoid, medicine, Animals, Bile, Humans, RNA-Seq, Pancreatic duct, Common Bile Duct, Keratin-19, Common bile duct, Hepatology, Gallbladder, Wnt signaling pathway, Cell Differentiation, Epithelial Cells, Original Articles, Cell biology, Organoids, 030104 developmental biology, medicine.anatomical_structure, Bile Ducts, Intrahepatic, Gene Expression Regulation, Liver, 030211 gastroenterology & hepatology, Original Article

وصف الملف: PDF; application/vnd.openxmlformats-officedocument.wordprocessingml.document

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9726cf8011fd07478f790d0cdca21a08