المؤلفون: Jingang Gui, Ian Dransfield, Jürgen Schwarze, Rodger Duffin, Adriano G. Rossi, Philippe M D Potey, Christopher Haslett, Jennifer M Felton, David A. Dorward, Ruth W. Craig, Christopher D. Lucas, Calum T. Robb, Jennifer A Cartwright

المصدر: Felton, J M, Dorward, D A, Cartwright, J, Potey, P M D, Robb, C T, Gui, J, Craig, R W, Schwarze, J, Haslett, C, Duffin, R, Dransfield, I, Lucas, C D & Rossi, A G 2020, ' Mcl-1 protects eosinophils from apoptosis and exacerbates allergic airway inflammation ', Thorax, vol. 75, no. 7, pp. 600-605 . https://doi.org/10.1136/thoraxjnl-2019-213204
Thorax

مصطلحات موضوعية: Pulmonary and Respiratory Medicine, Allergic airway inflammation, Transgene, Apoptosis, Mice, Transgenic, Brief Communication, Leukocyte Count, Mice, 03 medical and health sciences, 0302 clinical medicine, immune system diseases, hemic and lymphatic diseases, Hypersensitivity, medicine, asthma mechanisms, Animals, allergic lung disease, neoplasms, 030304 developmental biology, 0303 health sciences, medicine.diagnostic_test, Effector, Kinase, business.industry, Eosinophil, respiratory system, Asthma, respiratory tract diseases, 3. Good health, Eosinophils, Disease Models, Animal, Bronchoalveolar lavage, medicine.anatomical_structure, Gene Expression Regulation, 030228 respiratory system, Immunology, eosinophil biology, Myeloid Cell Leukemia Sequence 1 Protein, RNA, Female, business, Airway, Bronchoalveolar Lavage Fluid

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5590db05029951e9c4ed70b8e912cdc2
https://hdl.handle.net/20.500.11820/6740e9e8-1b83-4e77-ae17-b57217d8e829

المؤلفون: Shanna K Nifoussi, Julie A Vrana, Aaron M Domina, Alfredo De Biasio, Jingang Gui, Mark A Gregory, Stephen R Hann, Ruth W Craig

المصدر: PLoS ONE, Vol 7, Iss 10, p e47060 (2012)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC3467206?pdf=render; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/44c4beca0b6b4370a1fa1cb8e3dadb1b

المؤلفون: M. Suresh, Eui Ho Kim, Jingang Gui, Brandon Neldner, Ruth W. Craig

المصدر: Virology. 490:75-82

مصطلحات موضوعية: 0301 basic medicine, Cellular differentiation, Cell, CD8-Positive T-Lymphocytes, Lymphocytic Choriomeningitis, Biology, Article, Mice, 03 medical and health sciences, hemic and lymphatic diseases, Virology, medicine, Animals, Humans, Lymphocytic choriomeningitis virus, Cytotoxic T cell, Viability assay, IL-2 receptor, PI3K/AKT/mTOR pathway, Effector, TOR Serine-Threonine Kinases, Cell Differentiation, Cell biology, Mice, Inbred C57BL, 030104 developmental biology, medicine.anatomical_structure, Myeloid Cell Leukemia Sequence 1 Protein, Immunologic Memory, CD8

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d927b7bcb68565dca22864285ed3b7d9

المؤلفون: Steven D. Shapiro, David H. Dockrell, Ruth W. Craig, Paul Collini, Mohammed Mohasin, Martin A. Bewley, Helen M. Marriott, Moira K. B. Whyte, David Singh, David R. Greaves, Julie Swales, Christopher E. Brightling, Peter J. Barnes, Louise E. Donnelly, Julie A. Preston, Richard C. Budd

المصدر: Bewley, M A, Preston, J A, Mohasin, M, Marriott, H M, Budd, R C, Swales, J, Collini, P, Greaves, D R, Craig, R W, Brightling, C E, Donnelly, L E, Barnes, P J, Singh, D, Shapiro, S D, Whyte, M & Dockrell, D H 2017, ' Impaired mitochondrial microbicidal responses in chronic obstructive pulmonary disease macrophages. ', American Journal of Respiratory and Critical Care Medicine . https://doi.org/10.1164/rccm.201608-1714OC
Bewley, M A, Preston, J A, Mohasin, M, Marriott, H M, Budd, R C, Swales, J, Collini, P, Greaves, D R, Craig, R W, Brightling, C E, Donnelly, L E, Barnes, P J, Singh, D, Shapiro, S D, Whyte, M K B & Dockrell, D H 2017, ' Impaired mitochondrial microbicidal responses in chronic obstructive pulmonary disease macrophages ', American Journal of Respiratory and Critical Care Medicine, vol. 196, no. 7, pp. 845–855 . https://doi.org/10.1164/rccm.201608-1714OC

مصطلحات موضوعية: 0301 basic medicine, Respiratory System, STREPTOCOCCUS-PNEUMONIAE, Apoptosis, HAEMOPHILUS-INFLUENZAE, Critical Care and Intensive Care Medicine, medicine.disease_cause, Bronchoalveolar Lavage, mitochondrial reactive oxygen species, Mice, Pulmonary Disease, Chronic Obstructive, Anti-Infective Agents, COPD, medicine.diagnostic_test, CD68, apoptosis, Myeloid leukemia, 11 Medical And Health Sciences, Flow Cytometry, HUMAN ALVEOLAR MACROPHAGES, Mitochondria, Streptococcus pneumoniae, Mitochondrial reactive oxygen species, OXYGEN SPECIES PRODUCTION, SMOKING, Life Sciences & Biomedicine, Pulmonary and Respiratory Medicine, Phagocytosis, Blotting, Western, Mice, Transgenic, PHAGOCYTOSIS, 03 medical and health sciences, Critical Care Medicine, General & Internal Medicine, COPD EXACERBATIONS, Macrophages, Alveolar, medicine, Animals, Humans, Science & Technology, business.industry, COMMUNITY-ACQUIRED PNEUMONIA, PNEUMOCOCCAL INFECTION, medicine.disease, respiratory tract diseases, Disease Models, Animal, Oxidative Stress, 030104 developmental biology, Bronchoalveolar lavage, Immunology, Alveolar macrophage, business, Oxidative stress

وصف الملف: application/pdf; application/vnd.openxmlformats-officedocument.wordprocessingml.document

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ca37696983422ddd3b3a071a6330e43
https://pubmed.ncbi.nlm.nih.gov/28637925

المؤلفون: Amanda J. Morales, Katherine A. Bessette, John A. Kelly, Ruth W. Craig, Jingang Gui, Sophie E. Maxey, Nora R. Ratcliffe

المصدر: International Immunology. 23:647-659

مصطلحات موضوعية: Male, Cell Survival, T-Lymphocytes, Transgene, Immunology, Mice, Transgenic, Endogeny, Thymus Gland, Biology, Andrology, Mice, Mice, Congenic, Stroma, Radioresistance, Animals, Humans, Immunology and Allergy, Involution (medicine), Progenitor cell, Thymocytes, General Medicine, Mice, Inbred C57BL, Thymocyte, Proto-Oncogene Proteins c-bcl-2, Myeloid Cell Leukemia Sequence 1 Protein, Female, Original Research Papers, Whole-Body Irradiation, CD8

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b525a41f1496edd09c33d6e2e0e2a45
https://doi.org/10.1093/intimm/dxr073

المؤلفون: Ruth W. Craig, Liping Qian, Steven J. Weintraub, Aaron M. Domina, Julie A. Vrana, Karen Braley, John M. Neveu, Christine K. Bieszczad, Ping Zhou, William S. Lane, Alfredo De Biasio

المصدر: Journal of Biological Chemistry. 282:23919-23936

مصطلحات موضوعية: G2 Phase, MAPK/ERK pathway, Cell division, Gene Expression, Mice, Transgenic, Biology, Biochemistry, Serine, Mice, Cell Line, Tumor, Gene expression, Animals, Humans, Phosphorylation, Threonine, Molecular Biology, Cells, Cultured, Cell Biology, Glutamic acid, Neoplasm Proteins, Cell biology, Proto-Oncogene Proteins c-bcl-2, Cell culture, Myeloid Cell Leukemia Sequence 1 Protein, Apoptosis Regulatory Proteins, Protein Processing, Post-Translational, Cell Division

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2ccdf8f0dac9bcf3b9bff78541ddafc
https://doi.org/10.1074/jbc.m700938200

المؤلفون: Norihisa Ishimura, David D. Moore, Gregory J. Gores, Karen Braley, Edwina S. Baskin-Bey, Ruth W. Craig, Steven F. Bronk, Hajime Isomoto, Wendong Huang

المصدر: Hepatology. 44:252-262

مصطلحات موضوعية: medicine.medical_specialty, Pyridines, Gene Expression, Receptors, Cytoplasmic and Nuclear, Apoptosis, Mice, Transgenic, Biology, Polymerase Chain Reaction, Fas ligand, Mice, Downregulation and upregulation, Internal medicine, Constitutive androstane receptor, Concanavalin A, medicine, Animals, fas Receptor, Receptor, Constitutive Androstane Receptor, bcl-2-Associated X Protein, Mice, Knockout, Liver injury, Hepatology, Liver Diseases, DNA, medicine.disease, Immunohistochemistry, Cytoprotection, Neoplasm Proteins, Mice, Inbred C57BL, Microscopy, Electron, bcl-2 Homologous Antagonist-Killer Protein, medicine.anatomical_structure, Endocrinology, Proto-Oncogene Proteins c-bcl-2, Hepatocyte, Mutation, Hepatocytes, Cancer research, Myeloid Cell Leukemia Sequence 1 Protein, Chemical and Drug Induced Liver Injury, human activities, Transcription Factors

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4de2db19881b9d5e0bac8f73ab73a23
https://doi.org/10.1002/hep.21236

المؤلفون: Ching-Yi Tsai, Yan Song, Amanda J. Morales, Tian Ma, Edward J. Usherwood, Jingang Gui, Ruth W. Craig, Zhuting Hu, Ethan Dmitrovsky, Li-Hao Huang

مصطلحات موضوعية: Cell Survival, T cell, Immunology, Mice, Transgenic, Vaccinia virus, Biology, CD8-Positive T-Lymphocytes, Microbiology, Interleukin 21, Virology, medicine, Vaccinia, Cytotoxic T cell, Animals, Humans, IL-2 receptor, Antigen-presenting cell, Interleukin 3, ZAP70, Natural killer T cell, Mice, Inbred C57BL, Disease Models, Animal, medicine.anatomical_structure, Insect Science, Pathogenesis and Immunity, Myeloid Cell Leukemia Sequence 1 Protein, Immunologic Memory

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48ad5688dadcd43c6138bbeff7f6dbff
https://europepmc.org/articles/PMC4338882/

المؤلفون: Roberto R. Rosato, Sonia C. Maggio, Peter Atadja, Ruth W. Craig, Paul Dent, Julie Vrana, Steven Grant, Jorge A. Almenara

المصدر: Molecular Cancer Therapeutics. 4:1772-1785

مصطلحات موضوعية: Cyclin-Dependent Kinase Inhibitor p21, Cancer Research, Time Factors, Protein Conformation, medicine.drug_class, Blotting, Western, Down-Regulation, Antineoplastic Agents, Apoptosis, HL-60 Cells, X-Linked Inhibitor of Apoptosis Protein, Hydroxamic Acids, Inhibitor of apoptosis, Jurkat cells, Membrane Potentials, Jurkat Cells, Cytosol, Cyclin-dependent kinase, Cell Line, Tumor, Roscovitine, medicine, Humans, Enzyme Inhibitors, Protein Kinase Inhibitors, Leukemia, biology, Reverse Transcriptase Polymerase Chain Reaction, Cell Cycle, Histone deacetylase inhibitor, Apoptosis Inducing Factor, Cytochromes c, U937 Cells, Flow Cytometry, medicine.disease, Free radical scavenger, Mitochondria, Neoplasm Proteins, XIAP, Histone Deacetylase Inhibitors, Proto-Oncogene Proteins c-bcl-2, Oncology, Purines, biology.protein, Cancer research, Myeloid Cell Leukemia Sequence 1 Protein, Histone deacetylase, Reactive Oxygen Species

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::052fcae0610e682cc515852a300b2e4d
https://doi.org/10.1158/1535-7163.mct-05-0157

المؤلفون: Matthew Brimmell, Jason W. O'Neill, Claire L. Dallman, Ruth W. Craig, Peter Johnson, Graham Packham, Amalia Mouzakiti, Fay Habens, Kam Y. J. Zhang, Jorg Michels, Eric G. Marcusson

المصدر: Oncogene. 23:4818-4827

مصطلحات موضوعية: Cancer Research, Programmed cell death, Lymphoma, B-Cell, Cell Survival, Biopsy, Apoptosis, Cell Cycle Proteins, medicine.disease_cause, Cleavage (embryo), Oligodeoxyribonucleotides, Antisense, Open Reading Frames, immune system diseases, Cell Line, Tumor, hemic and lymphatic diseases, Genetics, medicine, Humans, neoplasms, Molecular Biology, Caspase, Oncogene Proteins, Cell Death, biology, Intrinsic apoptosis, Transfection, Thionucleotides, Cell culture, Caspases, biology.protein, Cancer research, Carcinogenesis, Plasmids

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd198defc8a57cebb37623abf7028ed5
https://doi.org/10.1038/sj.onc.1207648