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المؤلفون: Christopher McBride, Lynnie Trzoss, Davide Povero, Milos Lazic, Geza Ambrus-Aikelin, Angelina Santini, Rama Pranadinata, Gretchen Bain, Ryan Stansfield, Jeffrey A. Stafford, James Veal, Ryan Takahashi, Justin Ly, Shu Chen, Liling Liu, Marika Nespi, Robert Blake, Arna Katewa, Tracy Kleinheinz, Swathi Sujatha-Bhaskar, Nandhini Ramamoorthi, Jessica Sims, Brent McKenzie, Mark Chen, Mark Ultsch, Matthew Johnson, Jeremy Murray, Claudio Ciferri, Steven T. Staben, Michael J. Townsend, Craig E. Stivala
المصدر: Journal of Medicinal Chemistry. 65:14721-14739
مصطلحات موضوعية: Drug Discovery, Molecular Medicine
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المؤلفون: Christopher, McBride, Lynnie, Trzoss, Davide, Povero, Milos, Lazic, Geza, Ambrus-Aikelin, Angelina, Santini, Rama, Pranadinata, Gretchen, Bain, Ryan, Stansfield, Jeffrey A, Stafford, James, Veal, Ryan, Takahashi, Justin, Ly, Shu, Chen, Liling, Liu, Marika, Nespi, Robert, Blake, Arna, Katewa, Tracy, Kleinheinz, Swathi, Sujatha-Bhaskar, Nandhini, Ramamoorthi, Jessica, Sims, Brent, McKenzie, Mark, Chen, Mark, Ultsch, Matthew, Johnson, Jeremy, Murray, Claudio, Ciferri, Steven T, Staben, Michael J, Townsend, Craig E, Stivala
المصدر: Journal of medicinal chemistry. 65(21)
مصطلحات موضوعية: Sulfonamides, Macaca fascicularis, Inflammasomes, NLR Family, Pyrin Domain-Containing 3 Protein, Oxazines, Animals, Humans
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المؤلفون: Nicolas Addington, Ryan Takahashi
مصطلحات موضوعية: Mathematics - Algebraic Geometry, Mathematics::Algebraic Geometry, Applied Mathematics, General Mathematics, Mathematics::Category Theory, FOS: Mathematics, Representation Theory (math.RT), Mathematics::Symplectic Geometry, Algebraic Geometry (math.AG), Mathematics - Representation Theory
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92c538f018c225bdedf1221c7e037c36
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المؤلفون: Robert Godemann, Kathleen Knüppel, Christian A.G.N. Montalbetti, Stefan Steinbacher, Myron Smith, Lawren C. Wu, Swathi Sujatha-Bhaskar, Jianwen Feng, Maureen Beresini, Jacob Z. Chen, Christine Everett, Pawan Bir Kohli, Susan Krüger, Joachim Kraemer, David A. Roberts, Sarah G. Hymowitz, Ryan Takahashi, Hans Brightbill, Paul A. McEwan, Nobuhiko Kayagaki, Yamin Zhang, Pui Loke, Georgette Castanedo, Charles Eigenbrot, Hai-Feng Cui, Nicole Blaquiere, Steven T. Staben, Brandon J. Bravo, Adam R. Johnson, Emily B. Gogol, Xiaolu Wang
المصدر: Journal of Medicinal Chemistry. 60:627-640
مصطلحات موضوعية: 0301 basic medicine, P50, High selectivity, Active Transport, Cell Nucleus, Protein Serine-Threonine Kinases, Heterocyclic Compounds, 4 or More Rings, Nf κb inducing kinase, Mice, 03 medical and health sciences, Dogs, 0302 clinical medicine, NF-kappa B p52 Subunit, Drug Discovery, Animals, Humans, Oxazoles, Protein Kinase Inhibitors, PI3K/AKT/mTOR pathway, Phosphoinositide-3 Kinase Inhibitors, Cell Nucleus, chemistry.chemical_classification, Binding Sites, Phosphoinositide 3-kinase, biology, Kinase, Imidazoles, NF-kappa B p50 Subunit, Isoxazoles, Heterocyclic Compounds, Bridged-Ring, Oxazepines, HEK293 Cells, 030104 developmental biology, chemistry, Biochemistry, 030220 oncology & carcinogenesis, biology.protein, Molecular Medicine, Structure based, HeLa Cells, Signal Transduction, Tricyclic
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المؤلفون: Jialin Mao, Oliver Hatley, Iain Gardner, Janak Wedagedera, Udoamaka Ezuruike, Ryan Takahashi
المصدر: Drug Metabolism and Pharmacokinetics. 35:S87
مصطلحات موضوعية: Pharmacology, chemistry.chemical_classification, Drug, Enzyme, Pharmacokinetics, Chemistry, media_common.quotation_subject, Pharmaceutical Science, Pharmacology (medical), media_common
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المؤلفون: Qin, Yue, Yung-Hsiang, Chen, Teresa, Mulder, Alan, Deese, Ryan, Takahashi, Patrick J, Rudewicz, Mark, Reynolds, Eric, Solon, Cornelis E C A, Hop, Harvey, Wong, S Cyrus, Khojasteh
المصدر: Drug metabolism and disposition: the biological fate of chemicals. 39(6)
مصطلحات موضوعية: Male, Metabolic Clearance Rate, Pyridines, Administration, Oral, Absorption, Rats, Rats, Sprague-Dawley, Feces, Structure-Activity Relationship, Dogs, Species Specificity, Animals, Anilides, Female, Hedgehog Proteins, Rats, Long-Evans, Tissue Distribution, Carbon Radioisotopes, Chromatography, High Pressure Liquid, Signal Transduction
URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::640d038636d6315213c9685c1ac0b874
https://pubmed.ncbi.nlm.nih.gov/21363998