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1
المؤلفون: John P. Burdick, Rohin S. Basi, Kaitlyn S. Burns, Paul M.M. Weers
المصدر: Biochimica et biophysica acta. Biomembranes. 1865(2)
مصطلحات موضوعية: Biophysics, Cell Biology, Biochemistry
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2دورية أكاديمية
المؤلفون: Kaveeta Dawaka, A Gupta, S Joshi, S Bajpai, H S Basi
المصدر: Journal of Nepal Medical Association, Vol 39, Iss 136 (2013)
مصطلحات موضوعية: Medicine (General), R5-920
وصف الملف: electronic resource
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3
المؤلفون: Anna Liao, Gary Probst, Pamela S. Keim, Kang Hu, Roy K. Hom, David A. Quincy, Michael S. Dappen, Grace T. Kwong, Jenifer Smith, Martin L. Neitzel, Ying-zi Xu, Elizabeth F. Brigham, Kevin P. Quinn, Frédérique Bard, Minghua Sun, Jing Wu, John-Michael Sauer, Dora Kholodenko, Hongbin Zhang, William Wallace, Matthew N. Mattson, Patricia Sacayon, Jacek Jagodzinski, Hing L. Sham, Brian T. Peterson, Simeon Bowers, Jennifer Marugg, Guriqbal S. Basi, Lee H. Latimer, Susanna S. Hemphill, Darren B. Dressen, Karina Wong, Kevin Tanaka, Michael P. Bova, Pamela Santiago, Daniel K. Ness, Anh P. Truong, Wes Zmolek, Lany Ruslim, Christopher Willits, Michael K. Lee, Andrei W. Konradi, Xiaocong M. Ye, Lam Nguyen, Chris M. Semko, Ted A. Yednock, Ruth N. Motter, Albert W. Garofalo, Erich Goldbach, Pearl Tanaka, Danielle L. Aubele
المصدر: Journal of Medicinal Chemistry. 56:5261-5274
مصطلحات موضوعية: Trifluoromethyl, biology, Stereochemistry, Quinoline, In vitro, chemistry.chemical_compound, chemistry, In vivo, Drug Discovery, biology.protein, medicine, Molecular Medicine, Structure–activity relationship, Chirality (chemistry), Amyloid precursor protein secretase, Semagacestat, medicine.drug
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4
المؤلفون: Ragna, Sannerud, Cary, Esselens, Paulina, Ejsmont, Rafael, Mattera, Leila, Rochin, Arun Kumar, Tharkeshwar, Greet, De Baets, Veerle, De Wever, Roger, Habets, Veerle, Baert, Wendy, Vermeire, Christine, Michiels, Arjan J, Groot, Rosanne, Wouters, Katleen, Dillen, Katlijn, Vints, Pieter, Baatsen, Sebastian, Munck, Rita, Derua, Etienne, Waelkens, Guriqbal S, Basi, Mark, Mercken, Marc, Vooijs, Mathieu, Bollen, Joost, Schymkowitz, Frederic, Rousseau, Juan S, Bonifacino, Guillaume, Van Niel, Bart, De Strooper, Wim, Annaert
مصطلحات موضوعية: Amyloid beta-Peptides, Adaptor Protein Complex 1, Amino Acid Motifs, Endosomes, Peptide Fragments, Rats, Substrate Specificity, Mice, Alzheimer Disease, Cell Line, Tumor, Presenilin-2, Presenilin-1, Animals, Humans, Amyloid Precursor Protein Secretases, Lysosomes
وصف الملف: Print-Electronic; application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::c5c028d17b3d033e77b773331674704a
https://lirias.kuleuven.be/handle/123456789/544673 -
5
المؤلفون: Thomas Kukar, Paul Robertson, Todd E. Golde, Barbara A. Cottrell, Karen Jansen-West, Kim Malphrus, Simone Eggert, Pritam Das, Maralyssa Bann, Edward H. Koo, Brenda D. Moore, Hiroko Maruyama, Sean A. Pintchovski, Guriqbal S. Basi, Zhao Ren, Thomas B. Ladd
المصدر: Journal of Biological Chemistry. 286:39804-39812
مصطلحات موضوعية: biology, Chemistry, P3 peptide, Cell Biology, Biochemistry, Presenilin, Biochemistry of Alzheimer's disease, Transmembrane domain, Alpha secretase, biology.protein, Amyloid precursor protein, Senile plaques, Molecular Biology, Amyloid precursor protein secretase
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::dfe3b3211653cd5cc94d1d7ad696a51a
https://doi.org/10.1074/jbc.m111.274696 -
6
المؤلفون: Chris M. Semko, Danielle L. Aubele, Guriqbal S. Basi, Wes Zmolek, Gary Probst, Matthew N. Mattson, Elizabeth F. Brigham, Erich Goldbach, Karina Wong, William A Wallace, John-Michael Sauer, Hing L. Sham, Lan K. Nguyen, Michael P. Bova, Andrei W. Konradi, Albert W. Garofalo, Susanna S. Hemphill, Darren B. Dressen, Kevin P. Quinn, Minghua Sun, Anh P. Truong, Simeon Bowers
المصدر: Bioorganic & Medicinal Chemistry Letters. 21:5791-5794
مصطلحات موضوعية: Stereochemistry, Clinical Biochemistry, Drug Evaluation, Preclinical, Pharmaceutical Science, Mice, Inbred Strains, Biochemistry, Amyloid beta-Protein Precursor, Inhibitory Concentration 50, Mice, Structure-Activity Relationship, chemistry.chemical_compound, Drug Discovery, Peptide synthesis, Animals, Structure–activity relationship, γ secretase, Enzyme Inhibitors, Molecular Biology, chemistry.chemical_classification, Sulfonamides, Amyloid beta-Peptides, Bicyclic molecule, Chemistry, Organic Chemistry, Combinatorial chemistry, Sulfonamide, Design synthesis, Drug Design, Molecular Medicine, Amyloid Precursor Protein Secretases, Selectivity, Heterocyclic Compounds, 3-Ring
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7
المؤلفون: John-Michael Sauer, Michael P. Bova, Michael A. Pleiss, Danielle L. Aubele, Elizabeth F. Brigham, Kevin P. Quinn, Balazs G. Szoke, Jennifer Marugg, Wes Zmolek, Andrei W. Konradi, Erich Goldbach, William A Wallace, Guriqbal S. Basi, Martin L. Neitzel, Jacek Jagodzinski, Susanna S. Hemphill
المصدر: Bioorganic & Medicinal Chemistry Letters. 21:3715-3720
مصطلحات موضوعية: Clinical Biochemistry, Notch signaling pathway, Pharmaceutical Science, Biochemistry, Inhibitory Concentration 50, Mice, Alzheimer Disease, Drug Discovery, medicine, Amyloid precursor protein, Animals, Caprolactam, Potency, Infusions, Parenteral, Enzyme Inhibitors, Molecular Biology, chemistry.chemical_classification, Amyloid beta-Peptides, Molecular Structure, biology, Organic Chemistry, Sulfonamide (medicine), Biological activity, medicine.disease, Peptide Fragments, Enzyme Activation, Enzyme, chemistry, biology.protein, Molecular Medicine, Amyloid Precursor Protein Secretases, Signal transduction, Alzheimer's disease, medicine.drug
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8
المؤلفون: Xiaocong M, Ye, Andrei W, Konradi, Jenifer, Smith, Danielle L, Aubele, Albert W, Garofalo, Jennifer, Marugg, Marty L, Neitzel, Chris M, Semko, Hing L, Sham, Minghua, Sun, Anh P, Truong, Jing, Wu, Hongbin, Zhang, Erich, Goldbach, John-Michael, Sauer, Elizabeth F, Brigham, Michael, Bova, Guriqbal S, Basi
المصدر: Bioorganic & Medicinal Chemistry Letters. 20:3502-3506
مصطلحات موضوعية: Sulfonamides, Organic Chemistry, Clinical Biochemistry, Pharmaceutical Science, Biochemistry, Drug Stability, Piperidines, Drug Discovery, Microsomes, Liver, Animals, Molecular Medicine, Protease Inhibitors, Amyloid Precursor Protein Secretases, Molecular Biology
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9
المؤلفون: Darren B. Dressen, Ying-Zi Xu, Jenifer L. Smith, Xiaocong M. Ye, Elizabeth F. Brigham, Erich Goldbach, Anh P. Truong, Hing L. Sham, Michael P. Bova, Jennifer Marugg, Guriqbal S. Basi, Jacek Jagodzinski, Hongbin Zhang, Michael A. Pleiss, Andrei W. Konradi, Albert W. Garofalo, John-Michael Sauer
المصدر: Bioorganic & Medicinal Chemistry Letters. 20:2195-2199
مصطلحات موضوعية: Models, Molecular, Clinical Biochemistry, Pharmaceutical Science, Pharmacology, Biochemistry, Mice, Structure-Activity Relationship, Piperidines, Alzheimer Disease, In vivo, Drug Discovery, Pyrazolopyridine, medicine, Amyloid precursor protein, Animals, Humans, Structure–activity relationship, Molecular Biology, chemistry.chemical_classification, Sulfonamides, biology, Organic Chemistry, Sulfonamide (medicine), Biological activity, Enzyme, chemistry, biology.protein, Molecular Medicine, Amyloid Precursor Protein Secretases, Amyloid precursor protein secretase, medicine.drug
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10
المؤلفون: Michael K. Lee, Schenk Dale B, Peter Seubert, Hadar Feinberg, Robin Barbour, Kelly Johnson-Wood, Menelas N. Pangalos, Amita Goel, Irene Griswold-Prenner, Linnea Diep, William I. Weis, Jingzhi Li, Davinder Gill, John P. Anderson, J. Steven Jacobsen, Thomas A. Comery, Donald Walker, Nicolas Piot, Guriqbal S. Basi, Angela Widom, Anthony Partridge, Jeanne Baker, Farshid Oshidari, Katerina Grantcharova
المصدر: Journal of Biological Chemistry. 285:3417-3427
مصطلحات موضوعية: Male, Genetically modified mouse, Heterozygote, medicine.medical_treatment, Molecular Conformation, Crystallography, X-Ray, Biochemistry, Epitopes, Mice, Immune system, Alzheimer Disease, In vivo, medicine, Animals, Humans, Molecular Biology, Amyloid beta-Peptides, Behavior, Animal, Linear epitope, biology, Cell Biology, Immunotherapy, medicine.disease, Recombinant Proteins, In vitro, Disease Models, Animal, Kinetics, Cross-Linking Reagents, Protein Structure and Folding, Immunology, biology.protein, Alzheimer's disease, Antibody
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54c127e58115c08c9d0fd96b9cce7c07
https://doi.org/10.1074/jbc.m109.045187
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