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1
المؤلفون: E de Billy, Paul A. Clarke, S M Hobbs, Laurence H. Pearl, Marissa V. Powers, Jennifer R. Smith, Paul Workman, Chrisostomos Prodromou
المصدر: Oncogene
مصطلحات موضوعية: Cancer Research, CDC37, Chaperonins, kinase, Receptor, ErbB-2, Cell Cycle Proteins, Article, Cell Line, Tumor, Genetics, HSP90, chaperone, Humans, Point Mutation, ASK1, HSP90 Heat-Shock Proteins, RNA, Small Interfering, Protein kinase A, Molecular Biology, biology, Cyclin-dependent kinase 4, Kinase, Cyclin-Dependent Kinase 4, Cyclin-Dependent Kinase 6, HCT116 Cells, Hsp90, Cell biology, Gene Expression Regulation, Neoplastic, Proto-Oncogene Proteins c-raf, Chaperone (protein), Colonic Neoplasms, Mutation, biology.protein, Cancer research, Cyclin-dependent kinase 6, client, Protein Binding
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المؤلفون: Loryman B, M E Devey, S M Hobbs, Isaacs Ab, H S Thompson, Norman A. Staines, P J Major, Ekong Ta
مصطلحات موضوعية: Pathology, medicine.medical_specialty, Immunology, Type II collagen, Antibody Affinity, Arthritis, Mice, Inbred Strains, Immunoglobulin G, Subclass, Mice, medicine, Immunology and Allergy, Animals, Autoantibodies, biology, Chemistry, Autoantibody, Antibodies, Monoclonal, medicine.disease, Titer, Immunization, Mice, Inbred DBA, Antibody Formation, biology.protein, Collagen, Antibody
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27f4711f46d0cadf7179a92249bec311
https://ora.ox.ac.uk/objects/uuid:0c3ebb15-25a8-418c-a3ce-703e4a5d172e -
3
المؤلفون: John Maher, S M Hobbs, May C I van Schalkwyk, Sjoukje J. C. van der Stegen, Sophie Burbridge, Carol Box, Scott Wilkie, Ana Parente Pereira, Suzanne A. Eccles, David M. Davies
المصدر: Journal of Clinical Immunology. 32:1059-1070
مصطلحات موضوعية: T-Lymphocytes, medicine.medical_treatment, Immunology, Receptors, Antigen, T-Cell, Breast Neoplasms, Context (language use), Biology, Immunotherapy, Adoptive, Viral vector, Interferon-gamma, Cancer immunotherapy, Cell Line, Tumor, medicine, Humans, Immunology and Allergy, Cells, Cultured, Adaptor Proteins, Signal Transducing, Cell Proliferation, Tumor microenvironment, Mucin-1, CD28, Signal transducing adaptor protein, Immunotherapy, Virology, Chimeric antigen receptor, Cell biology, Interleukin-2, Female, Signal Transduction
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4
المؤلفون: Suzanne A. Eccles, S M Hobbs, Neil P. Jones, Matilda Katan, Joanna C. Peak
المصدر: Oncogene. 27:2823-2832
مصطلحات موضوعية: Male, Cancer Research, medicine.medical_specialty, Cell, Nerve Tissue Proteins, Biology, Extracellular matrix, Cell Line, Tumor, Internal medicine, Cell Adhesion, Genetics, medicine, Extracellular, Guanine Nucleotide Exchange Factors, Humans, Cell adhesion, Molecular Biology, Gene knockdown, Phospholipase C gamma, Chemotaxis, Carcinoma, Prostatic Neoplasms, rap1 GTP-Binding Proteins, Cell biology, medicine.anatomical_structure, Endocrinology, Cell culture, Rap1, Signal transduction, Signal Transduction
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المؤلفون: Guo Cai Huang, Richard J. Epstein, S M Hobbs, M Walton
المصدر: British Journal of Cancer
مصطلحات موضوعية: p53, Cancer Research, Receptor, ErbB-2, medicine.medical_treatment, Breast Neoplasms, Biology, Ligands, Transfection, ErbB2, Downregulation and upregulation, Epidermal growth factor, Tumor Cells, Cultured, medicine, Humans, Growth factor receptor inhibitor, Epidermal growth factor receptor, skin and connective tissue diseases, neoplasms, Cell growth, Growth factor, Cell Cycle, Molecular and Cellular Pathology, apoptosis, Genes, erbB-2, Up-Regulation, Kinetics, Phenotype, Oncology, Cancer cell, Disease Progression, Cancer research, biology.protein, Female, Tumor Suppressor Protein p53, A431 cells, Signal Transduction
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المؤلفون: Nicki Tiffin, CR Pinkerton, S M Hobbs, H A Cocker, Kathy Pritchard-Jones, Lloyd R. Kelland
المصدر: British Journal of Cancer
مصطلحات موضوعية: mdm2, Cancer Research, Antineoplastic Agents, P-glycoprotein, Transfection, resistance, Inhibitory Concentration 50, Proto-Oncogene Proteins, Rhabdomyosarcoma, Tumor Cells, Cultured, medicine, Humans, ATP Binding Cassette Transporter, Subfamily B, Member 1, Nuclear protein, Child, neoplasms, Etoposide, Cisplatin, Oncogene, biology, Nuclear Proteins, Proto-Oncogene Proteins c-mdm2, Regular Article, mdr-1, medicine.disease, Molecular biology, Gene Expression Regulation, Neoplastic, Multiple drug resistance, enzymes and coenzymes (carbohydrates), Oncology, Doxorubicin, Drug Resistance, Neoplasm, Vincristine, biology.protein, Cancer research, Mdm2, Cell Division, Plasmids, medicine.drug
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المؤلفون: Melanie Valenti, Paul Workman, Swee Y. Sharp, L. Brunton, Lloyd R. Kelland, S M Hobbs
المصدر: Molecular Pharmacology. 58:1146-1155
مصطلحات موضوعية: Mitomycin, Transplantation, Heterologous, Gene Expression, Mice, Nude, Biology, Models, Biological, Mice, chemistry.chemical_compound, In vivo, NAD(P)H Dehydrogenase (Quinone), Tumor Cells, Cultured, medicine, Animals, Humans, Streptonigrin, Pharmacology, Diaziquone, Antibiotics, Antineoplastic, Expression vector, Mitomycin C, Dicoumarol, Molecular biology, Transplantation, Disease Models, Animal, Treatment Outcome, chemistry, Reducing Agents, Colonic Neoplasms, Molecular Medicine, Tirapazamine, HT29 Cells, Neoplasm Transplantation, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2624f1ef56ee34b0b62a5ceac3ba16a7
https://doi.org/10.1124/mol.58.5.1146 -
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المؤلفون: S M Hobbs, Julian Blagg, Will Court, Aurélie Mallinger, Olajumoke O. Popoola, Dirk Wienke, Christina Esdar, Kai Schiemann, Paul A. Clarke, Rahul S. Samant, Paul Workman, Sue Eccles, Maria-Jesus Ortiz-Ruiz, Mark Stubbs, Rosemary Burke, Robert TePoele
المصدر: Cancer Research. 76:3869-3869
مصطلحات موضوعية: Genetics, Cancer Research, Pregnane X receptor, Oncology, Cell culture, Kinase, Wnt signaling pathway, Cyclin-dependent kinase 8, Phosphorylation, Signal transduction, Biology, Transcription factor, Molecular biology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::90af652c2c380e8401260272d6d280e9
https://doi.org/10.1158/1538-7445.am2016-3869 -
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المؤلفون: Paul Workman, Joanna L. Holmes, S M Hobbs, Swee Y. Sharp
المصدر: Cancer research. 68(4)
مصطلحات موضوعية: Cancer Research, ATPase, Lactams, Macrocyclic, Biology, Transfection, Hsp90 inhibitor, Heat shock protein, Cell Line, Tumor, Neoplasms, polycyclic compounds, Benzoquinones, Humans, HSP90 Heat-Shock Proteins, Phosphorylation, RNA, Small Interfering, Gene knockdown, Activator (genetics), HCT116 Cells, Molecular biology, Hsp90, Oncology, biology.protein, Signal transduction, HT29 Cells, Molecular Chaperones, Signal Transduction
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01381ce689679cff724112cc7287fedf
https://pubmed.ncbi.nlm.nih.gov/30602623 -
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المؤلفون: R J, Knox, T C, Jenkins, S M, Hobbs, S, Chen, R G, Melton, P J, Burke
المصدر: Cancer research. 60(15)
مصطلحات موضوعية: Niacinamide, Aziridines, Antineoplastic Agents, Pyridinium Compounds, Fibroblasts, Transfection, Cell Line, Substrate Specificity, Isoenzymes, Cricetulus, Cricetinae, NAD(P)H Dehydrogenase (Quinone), Tumor Cells, Cultured, Animals, Humans, Prodrugs, Drug Screening Assays, Antitumor, Biotransformation
URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::94e30d7f85b17b32a326ab4308fa5565
https://pubmed.ncbi.nlm.nih.gov/10945627