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1Non-Peptidic CRF1 Receptor Antagonists for the Treatment of Anxiety, Depression and Stress Disorders
المؤلفون: S De Lombaert, John H. Kehne
المصدر: Current Drug Target -CNS & Neurological Disorders. 1:467-493
مصطلحات موضوعية: Stress Disorders, Traumatic, Pharmacology, Clinical Trials as Topic, Depressive Disorder, medicine.drug_class, business.industry, General Neuroscience, Drug Evaluation, Preclinical, medicine.disease, Receptor antagonist, Bioinformatics, Anxiety Disorders, Receptors, Corticotropin-Releasing Hormone, Anxiolytic, Anxiogenic, Genetic model, medicine, Animals, Humans, Major depressive disorder, Antidepressant, Anxiety, medicine.symptom, Receptor, business
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5f13bfd86c9710759f7920cc02f0c13
https://doi.org/10.2174/1568007023339049 -
2
المؤلفون: Paula Savage, Angelo J. Trapani, Arco Y. Jeng, Charles W. Bruseo, Mary Chou, S. De Lombaert, Michael E. Beil
المصدر: Life Sciences. 67:1025-1033
مصطلحات موضوعية: medicine.medical_specialty, education.field_of_study, Chemistry, Endothelin converting enzyme 1, General Medicine, Prodrug, Endothelin 1, General Biochemistry, Genetics and Molecular Biology, Endocrinology, Atrial natriuretic peptide, In vivo, Internal medicine, Renin–angiotensin system, medicine, General Pharmacology, Toxicology and Pharmaceutics, Endothelin receptor, education, Neprilysin
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3
المؤلفون: John Moliterni, Arco Y. Jeng, John Fitt, Lisa B. Stamford, Eli M. Wallace, L. Blanchard, Mary Chou, S. De Lombaert, Jenny Tan, Paula Savage, Daniel Hoyer, N. Marcopoulos, D. Simonsbergen, Angelo J. Trapani, Yoshitaka Satoh
المصدر: Journal of Medicinal Chemistry. 43:488-504
مصطلحات موضوعية: Male, medicine.hormone, Endothelin converting enzyme 1, Stereochemistry, Organophosphonates, Tetrazoles, Blood Pressure, Endothelin-Converting Enzymes, Rats, Sprague-Dawley, Endothelins, Structure-Activity Relationship, chemistry.chemical_compound, In vivo, Drug Discovery, medicine, Animals, Aspartic Acid Endopeptidases, Humans, Structure–activity relationship, Tetrazole, Enzyme Inhibitors, Protein Precursors, education, Benzofurans, education.field_of_study, Endothelin-1, biology, Phosphoramidon, Metalloendopeptidases, Stereoisomerism, Endothelin 1, Combinatorial chemistry, Rats, chemistry, Enzyme inhibitor, biology.protein, Molecular Medicine
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4
المؤلفون: Mark D. Erion, L. Blanchard, Angelo J. Trapani, L. El‐Chehabi, Jenny Tan, Carol Berry, R. D. Ghai, S. De Lombaert, Yumi Sakane
المصدر: ChemInform. 25
مصطلحات موضوعية: chemistry.chemical_compound, Chemistry, Stereochemistry, General Medicine, Prodrug, Neprilysin, Phosphonate
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5
المؤلفون: S. De Lombaert, R. D. Ghai, Yumi Sakane, Carol Berry, Jenny Tan, L. Blanchard
المصدر: ChemInform. 26
مصطلحات موضوعية: Stereochemistry, Chemistry, Potency, General Medicine, Neutral Endopeptidase 24.11
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6
المؤلفون: Angelo J. Trapani, Carol Berry, R. D. Ghai, S. De Lombaert, L. Blanchard
المصدر: ChemInform. 26
مصطلحات موضوعية: chemistry.chemical_compound, Orally active, Chemistry, Stereochemistry, General Medicine, Neutral Endopeptidase 24.11, Prodrug, Phosphonate
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7
المؤلفون: S. De Lombaert, Arco Y. Jeng
المصدر: ChemInform. 29
مصطلحات موضوعية: chemistry.chemical_classification, Enzyme, chemistry, Biochemistry, General Medicine, Endothelin receptor
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8
المؤلفون: Michael A. Moskal, S. De Lombaert, Yoshitaka Satoh, John Moliterni, Jenny Tan, Nicholas Marcopulos, Eli M. Wallace
المصدر: ChemInform. 29
مصطلحات موضوعية: chemistry.chemical_classification, chemistry.chemical_compound, Schiff base, chemistry, Stereochemistry, Tetrazole, General Medicine, Alkylation, Amino acid
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9
المؤلفون: S. De Lombaert, Paula Savage, D. Delgrande, Arco Y. Jeng, Suraj S. Shetty
المصدر: Journal of Cardiovascular Pharmacology. 31:S68-S70
مصطلحات موضوعية: Male, Stereochemistry, Endothelin converting enzyme 1, Organophosphonates, Tetrazoles, Blood Pressure, Endothelin-Converting Enzymes, In Vitro Techniques, Kidney, Renal Circulation, Rats, Sprague-Dawley, medicine, Animals, Aspartic Acid Endopeptidases, Humans, Protease Inhibitors, Chelation, Protein Precursors, education, Pharmacology, chemistry.chemical_classification, education.field_of_study, Endothelin-1, biology, Endothelins, Metalloendopeptidases, Biological activity, Endothelin 1, Recombinant Proteins, Rats, Kinetics, Enzyme, chemistry, Mechanism of action, Enzyme inhibitor, biology.protein, medicine.symptom, Cardiology and Cardiovascular Medicine, Endothelin receptor, Protein Binding
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b159e76078568d7329022002c7f2ec5a
https://doi.org/10.1097/00005344-199800001-00022 -
10
المؤلفون: S. De Lombaert, K. Tanzawa, K. Shimada, Paula Savage, Arco Y. Jeng
المصدر: Journal of cardiovascular pharmacology. 31
مصطلحات موضوعية: Endothelin converting enzyme 1, Stereochemistry, Mutant, Endothelin-Converting Enzymes, chemistry.chemical_compound, Structure-Activity Relationship, medicine, Animals, Aspartic Acid Endopeptidases, Humans, Protease Inhibitors, education, Pharmacology, chemistry.chemical_classification, education.field_of_study, biology, Phosphoramidon, Wild type, Metalloendopeptidases, Amino acid, Rats, Enzyme, chemistry, Mechanism of action, Biochemistry, Enzyme inhibitor, Mutation, biology.protein, Mutagenesis, Site-Directed, medicine.symptom, Cardiology and Cardiovascular Medicine
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7812d4d3d0e0a986f34263c6323282bf
https://pubmed.ncbi.nlm.nih.gov/9595388