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1
المؤلفون: Michael J.E. Sternberg, Gillian Smith, S.Wynne Ellis, G P Hayhurst, Mandy M. S. Wong, Anthony P. Simula, Tracy Lightfoot, C. Roland Wolf, Martin S. Lennard, Mark J. Ackland, Geoffrey T. Tucker
المصدر: Journal of Biological Chemistry. 270:29055-29058
مصطلحات موضوعية: Alanine, chemistry.chemical_classification, Aspartic Acid, Binding Sites, biology, Chemistry, Stereochemistry, Wild type, Active site, Cell Biology, Glutamic acid, Biochemistry, Mixed Function Oxygenases, Amino acid, Structure-Activity Relationship, Cytochrome P-450 CYP2D6, Cytochrome P-450 Enzyme System, Glycine, Aspartic acid, biology.protein, Humans, Asparagine, Oxidation-Reduction, Molecular Biology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f5a1dde07c2dafb68d25a7908b5f2dc
https://doi.org/10.1074/jbc.270.49.29055 -
2Catalytic activities of human debrisoquine 4-hydroxylase cytochrome P450 (CYP2D6) expressed in yeast
المؤلفون: H.Frank Woods, Colin J. Henderson, Anthony P. Simula, Philip F. Watson, Martin S. Lennard, S.Wynne Ellis, Michael S. Ching, Geoffrey T. Tucker
المصدر: Biochemical Pharmacology. 44:617-620
مصطلحات موضوعية: Metabolite, Sparteine, Saccharomyces cerevisiae, Transfection, Biochemistry, Mixed Function Oxygenases, Substrate Specificity, chemistry.chemical_compound, Cytochrome P-450 Enzyme System, Microsomes, Cytochrome P-450 Enzyme Inhibitors, Humans, Pharmacology, chemistry.chemical_classification, Expression vector, biology, Molecular mass, Cytochrome P450, biology.organism_classification, Molecular biology, Recombinant Proteins, Yeast, Enzyme, Cytochrome P-450 CYP2D6, chemistry, Microsomes, Liver, biology.protein, Microsome, Metoprolol, Plasmids
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3
المؤلفون: S.Wynne Ellis, Didier Bréant, Franck Broly, Delphine Allorge, Dany Chevalier, Jacky Harlow, Joey Chowdry, Jean-Marc Lo-Guidice, Michel Lhermitte, Christelle Cauffiez, Frank E. Blaney, Geoffrey T. Tucker
المصدر: Proteins. 59(2)
مصطلحات موضوعية: Genotype, Saccharomyces cerevisiae, Reductase, Arginine, Biochemistry, Dextromethorphan, Polymerase Chain Reaction, Substrate Specificity, Gene Frequency, Structural Biology, Microsomes, Humans, Histidine, Enzyme kinetics, Homology modeling, Cloning, Molecular, Molecular Biology, Allele frequency, chemistry.chemical_classification, biology, Genetic Variation, Molecular biology, Enzyme assay, Recombinant Proteins, Amino acid, Debrisoquin, Kinetics, Enzyme, Phenotype, chemistry, Amino Acid Substitution, Cytochrome P-450 CYP2D6, biology.protein, Heterologous expression, Oxidation-Reduction
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4
المؤلفون: Geoffrey T. Tucker, Shin-ichi Iwata, Sumio Shinoda, Shino Kuramoto, Shigeo Yamamoto, Nobuhiko Ueda, Shinsaku Naito, Kimio Kiryu, Kazuo Asaoka, Shizuo Narimatsu, Nobumitsu Hanioka, Hiroyuki Hichiya, Masahiro Nomoto, S.Wynne Ellis, Atsuro Miyata, Tetsuo Satoh
المصدر: Biochemical pharmacology. 68(1)
مصطلحات موضوعية: endocrine system, animal structures, DNA, Complementary, Molecular Sequence Data, Gene Expression, Hydroxylation, Biochemistry, Antibodies, law.invention, chemistry.chemical_compound, law, biology.animal, Complementary DNA, Animals, Humans, Amino Acid Sequence, RNA, Messenger, Cloning, Molecular, Cytochrome P450 Family 2, Pharmacology, chemistry.chemical_classification, biology, Base Sequence, Sequence Homology, Amino Acid, Bufuralol, Marmoset, Cytochrome P450, Callithrix, Molecular biology, Quinidine, Recombinant Proteins, Rats, Reverse transcription polymerase chain reaction, Alcohol Oxidoreductases, Enzyme, chemistry, Liver, Recombinant DNA, biology.protein, Microsomes, Liver, Female, Aryl Hydrocarbon Hydroxylases, Primer (molecular biology)
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5
المؤلفون: Martin S. Lennard, H. Kim Crewe, S.Wynne Ellis, Geoffrey T. Tucker
المصدر: Biochemical pharmacology. 53(2)
مصطلحات موضوعية: Adult, Male, medicine.medical_specialty, Antineoplastic Agents, Hormonal, Hydroxylation, Biochemistry, Mixed Function Oxygenases, chemistry.chemical_compound, Cytochrome P-450 Enzyme System, Internal medicine, Cytochrome P-450 CYP3A, medicine, Humans, Pharmacology, biology, CYP3A4, Cytochrome P450, Middle Aged, Antiestrogen, Tamoxifen, Endocrinology, chemistry, Cytochrome P-450 CYP2D6, Steroid 16-alpha-Hydroxylase, Dealkylation, Steroid Hydroxylases, biology.protein, Microsome, Microsomes, Liver, Female, Aryl Hydrocarbon Hydroxylases, medicine.drug
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6
المؤلفون: Richard A. Tschirret-Guth, G P Hayhurst, Gillian Smith, Richard Mackman, Geoffrey T. Tucker, Paul R. Ortiz de Montellano, S.Wynne Ellis, C. Roland Wolf, Martin S. Lennard
المصدر: Archives of biochemistry and biophysics. 331(1)
مصطلحات موضوعية: Models, Molecular, Stereochemistry, Biophysics, Glycine, Glutamic Acid, Protoporphyrins, Saccharomyces cerevisiae, Ring (chemistry), Biochemistry, Mixed Function Oxygenases, chemistry.chemical_compound, Structure-Activity Relationship, Cytochrome P-450 Enzyme System, Side chain, Electrochemistry, Humans, Asparagine, Carboxylate, Molecular Biology, Pyrrole, Aspartic Acid, Binding Sites, biology, Molecular Structure, Aryl, Active site, Porphyrin, Hydrazines, chemistry, Cytochrome P-450 CYP2D6, Mutation, biology.protein, Imines
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7
المؤلفون: Johanne Scott, Donald R. Buhler, S.Wynne Ellis, Stephen G. George
المصدر: Marine Environmental Research. 42:26-27
مصطلحات موضوعية: CYP7B1, CYP3A, Cytochrome P450, General Medicine, Aquatic Science, Monooxygenase, Biology, Oceanography, Pollution, Molecular biology, In vitro, Biochemistry, biology.protein, Functional studies