المؤلفون: Stephan Krieg, Thomas Rohde, Tobias Rausch, Luise Butthof, Lena Wendler-Link, Christoph Eckert, Kai Breuhahn, Bruno Galy, Jan Korbel, Maximilian Billmann, Marco Breinig, Darjus F. Tschaharganeh

المصدر: Genome Medicine, Vol 16, Iss 1, Pp 1-21 (2024)

مصطلحات موضوعية: Synthetic lethality, Chromosome 8p deletion, SCNAs, MFRN1/2 paralog buffering, Medicine, Genetics, QH426-470

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1756-994X

URL الوصول: https://doaj.org/article/d7c5dfffb2304419945cd7a2bce10c8a

المؤلفون: Krieg, Stephan, Rohde, Thomas, Rausch, Tobias, Butthof, Luise, Wendler-Link, Lena, Eckert, Christoph, Breuhahn, Kai, Galy, Bruno, Korbel, Jan, Billmann, Maximilian^{Aff2, IDs1307302401357w_cor10}, Breinig, Marco^{Aff1, IDs1307302401357w_cor11}, Tschaharganeh, Darjus F.^{Aff1, IDs1307302401357w_cor12}

المصدر: Genome Medicine. 16(1)

المؤلفون: Yalei Chen, Sudha M. Sadasivan, Ruicong She, Indrani Datta, Kanika Taneja, Dhananjay Chitale, Nilesh Gupta, Melissa B. Davis, Lisa A. Newman, Craig G. Rogers, Pamela L. Paris, Jia Li, Benjamin A. Rybicki, Albert M. Levin

المصدر: BMC Medical Genomics, Vol 13, Iss 1, Pp 1-15 (2020)

مصطلحات موضوعية: SCNAs, Race, Breast cancer, Prostate cancer, Genetic ancestry, Internal medicine, RC31-1245, Genetics, QH426-470

وصف الملف: electronic resource

Relation: http://link.springer.com/article/10.1186/s12920-020-00765-2; https://doaj.org/toc/1755-8794

URL الوصول: https://doaj.org/article/1d3ce2dbd2984ac6b519c44893496374

المؤلفون: Bastien Nguyen, David Venet, Matteo Lambertini, Christine Desmedt, Roberto Salgado, Hugo Mark Horlings, Françoise Rothé, Christos Sotiriou

المصدر: Breast Cancer Research, Vol 21, Iss 1, Pp 1-10 (2019)

مصطلحات موضوعية: Breast cancer, Pregnancy, Genomics, SCNAs, Mutational landscape, Whole genome sequencing, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

Relation: http://link.springer.com/article/10.1186/s13058-019-1111-6; https://doaj.org/toc/1465-542X

URL الوصول: https://doaj.org/article/1cb3083c1c504b55b7568ee0656a41bf

المؤلفون: Pierfrancesco Polo, Niklas Gremke, Thorsten Stiewe, Michael Wanzel

المصدر: Cells, Vol 11, Iss 11, p 1762 (2022)

مصطلحات موضوعية: autophagy, cancer metabolism, aerobic glycolysis, somatic copy number alterations (SCNAs), copy number loss, haploinsufficiency, Cytology, QH573-671

وصف الملف: electronic resource

Relation: https://www.mdpi.com/2073-4409/11/11/1762; https://doaj.org/toc/2073-4409

URL الوصول: https://doaj.org/article/219bfd315aa044868d1679dbef9f65db

المؤلفون: Chen, Yalei^{Aff1, Aff2}, Sadasivan, Sudha M., She, Ruicong^{Aff1, Aff2}, Datta, Indrani^{Aff1, Aff2}, Taneja, Kanika, Chitale, Dhananjay^{Aff3, Aff4}, Gupta, Nilesh, Davis, Melissa B., Newman, Lisa A., Rogers, Craig G., Paris, Pamela L., Li, Jia^{Aff1, Aff2}, Rybicki, Benjamin A., Levin, Albert M.^{Aff1, Aff2}

المصدر: BMC Medical Genomics. 13(1)

المؤلفون: Pierfrancesco Polo, Niklas Gremke, Thorsten Stiewe, Michael Wanzel

المساهمون: Medizin

المصدر: Cells; Volume 11; Issue 11; Pages: 1762

مصطلحات موضوعية: Lung Neoplasms, DNA Copy Number Variations, Carcinoma, Non-Small-Cell Lung, Autophagy, Medizin, Humans, autophagy, cancer metabolism, aerobic glycolysis, somatic copy number alterations (SCNAs), copy number loss, haploinsufficiency, metabolic cancer therapy, Beclin-1, General Medicine, ddc:610, Medical sciences Medicine, metabolic cancer ther

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c420ec720161ebb58be42d88ffcc77e

المؤلفون: Nguyen, Bastien^{Aff1, Aff2}, Venet, David^Aff1, Lambertini, Matteo^{Aff1, Aff5}, Desmedt, Christine^Aff1, Salgado, Roberto^{Aff1, Aff3}, Horlings, Hugo Mark^Aff4, Rothé, Françoise^Aff1, Sotiriou, Christos^Aff1

المصدر: Breast Cancer Research. 21(1)

المؤلفون: Hao Wang, Lei Wang, Keyi Jia, Yu Liu, Sha Zhao, Wei Li, Caicun Zhou, Minlin Jiang, Bin Chen, Yayi He

المصدر: Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 11, Iss 10, Pp 2983-2994 (2021)

مصطلحات موضوعية: Genome instability, PD-L1, programmed death ligand 1, BRCA, breast cancer susceptibility gene, ICI, immune checkpoint inhibitor, medicine.medical_treatment, MUTYH, MutY homolog, cGAS, cyclic GMP–AMP synthase, Review, DNA damage response, Malignant transformation, ORR, objective response rate, PCR, polymerase chain reaction, 0302 clinical medicine, SCNAs, somatic copy number alterations, FDA, United State Food and Drug Administration, Cancer immunotherapy, MGMT, O6-methylguanine methyltransferase, PD-1, RB1, retinoblastoma 1, General Pharmacology, Toxicology and Pharmaceutics, BER, base excision repair, RAD51C, RAD51 homolog C, 0303 health sciences, TME, tumor microenvironment, TP53, tumor protein P53, cGAS–STING, MSI, microsatellite instability, TRIF, Toll-interleukin 1 receptor domain-containing adaptor inducing INF-β, PFS, progression-free survival, STAT, signal transducer and activator of transcription, NEK1, NIMA-related kinase 1, Tumor microenvironment, PALB2, partner and localizer of BRCA2, RSR, replication stress response, 030220 oncology & carcinogenesis, Immunotherapy, PARP, poly-ADP ribose polymerase, JAK, Janus kinase, IHC, immunohistochemistry, Genomic instability, PD-L1, DSBs, double-strand breaks, DNA repair, DNA damage, CHK1, checkpoint kinase 1, IRF1, interferon regulatory factor 1, MLH1, MutL homolog 1, RM1-950, MMR, mismatch repair, STING, stimulator of interferon genes, Biology, MNT, MAX network transcriptional repressor, DDR, DNA damage response, MSH2/6, MutS protein homologue-2/6, OS, overall survival, RPA, replication protein A, 03 medical and health sciences, GSK3β, glycogen synthase kinase 3β, NER, nucleotide excision repair, NSCLC, non-small cell lung cancer, MyD88, myeloid differentiation factor 88, ssDNA, single-stranded DNA, medicine, DAMP, damage-associated molecular patterns, DR, direct repair, 030304 developmental biology, BAP1, BRCA1-associated protein 1, BRAF, v-RAF murine sarcoma viral oncogene homologue B, TLR4, Toll-like receptor 4, Cancer, NGS, next generation sequencing, ATM, ataxia-telangiectasia mutated, NIMA, never-in-mitosis A, medicine.disease, CHEK, cell-cycle checkpoint kinase, PD-1, programmed death 1, MAD1, mitotic arrest deficient-like 1, body regions, IFNγ, interferon gamma, TILs, tumor-infiltrating lymphocytes, TBK1, TANK-binding kinase 1, ATR, ataxia telangiectasia and Rad3 related, Cancer research, NHEJ, nonhomologous end-joining, Therapeutics. Pharmacology, HMGB1, high mobility group box-1, HRR, homologous recombination repair, XRCC4, X-ray repair cross complementing protein 4, TMB, tumor mutational burden

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbe73202674a833d134ec811bcbf7332
https://doi.org/10.1016/j.apsb.2021.01.003

المؤلفون: Guolong Liao, Hanqi Lei, Xiangwei Yang, Xing Fu, Fu Shi, Donggen Jiang, Haiyun Xiong, Yafei Yang, Yu-Peng Feng, Jun Pang, Bing-Biao Lin

المصدر: Computational and Structural Biotechnology Journal
Computational and Structural Biotechnology Journal, Vol 19, Iss, Pp 4941-4953 (2021)

مصطلحات موضوعية: Microarray, DFS, disease-free survival, MDSCs, myeloid-derived suppressor cells, AUC, Area under the dose-response curve, Biochemistry, k-NN, K-nearest neighbor, GEP, gene expression profile, Androgen deprivation therapy, Transcriptome, CTLA-4, cytotoxic T-lymphocyte associated protein-4, chemistry.chemical_compound, Prostate cancer, DEmiRs, differentially expressed miRNAs, SCNAs, somatic copy number alterations, Structural Biology, TGFβ, transforming growth factor β, BCR, biochemical recurrence, ICB, immune checkpoint blockade, GEO, Gene Expression Omnibus, NTP, Nearest template prediction, TMB, tumor mutation burden, PD-1, programmed cell death protein-1, NEPC, neuroendocrine prostate cancer, Computer Science Applications, NMF, non-negative matrix factorization, CCLs, cancer cell lines, Tregs, regulatory T cells, miRNAs, EMT, epithelial-mesenchymal transition, mCRPC, metastatic castration-resistant prostate cancer, Biotechnology, Research Article, FDR, false discovery rate, SubMap, Subclass mapping, Molecular subtypes, Biophysics, PCa, prostate cancer, Biology, KEGG, Kyoto Encyclopedia of Genes and Genomes, Olaparib, OS, overall survival, GSEA, Gene Set Enrichment Analysis, microRNA, GO, Gene Ontology, ssGSEA, single-sample gene set enrichment analysis, Genetics, medicine, TNAs, tumor neoantigens, PTEN, miRNAs, microRNAs, IFN, interferon, ADT, androgen deprivation therapy, ComputingMethodologies_COMPUTERGRAPHICS, Taxane, medicine.disease, PD-L1, programmed death-ligand 1, chemistry, Cancer research, biology.protein, TCGA, The Cancer Genome Atlas, MIRcor, miRNA-correlated, AR, androgen receptor, Heterogeneity, TP248.13-248.65, CAFs, cancer-associated fibroblasts

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f138460d0ba30547d9145ec00105384e
http://europepmc.org/articles/PMC8433071