المؤلفون: Grinberg, Marianna, Stöber, Regina M., Edlund, Karolina, Rempel, Eugen, Godoy, Patricio, Reif, Raymond, Widera, Agata, Madjar, Katrin, Schmidt-Heck, Wolfgang, Marchan, Rosemarie, Sachinidis, Agapios, Spitkovsky, Dimitry, Hescheler, Jürgen, Carmo, Helena, Arbo, Marcelo D., van de Water, Bob, Wink, Steven, Vinken, Mathieu, Rogiers, Vera, Escher, Sylvia, Hardy, Barry, Mitic, Dragana, Myatt, Glenn, Waldmann, Tanja, Mardinoglu, Adil, Damm, Georg, Seehofer, Daniel, Nüssler, Andreas, Weiss, Thomas S., Oberemm, Axel, Lampen, Alfons, Schaap, Mirjam M., Luijten, Mirjam, van Steeg, Harry, Thasler, Wolfgang E., Kleinjans, Jos C. S., Stierum, Rob H., Leist, Marcel, Rahnenführer, Jörg, Hengstler, Jan G.^{Aff2, IDs002040141400x_cor40}

المصدر: Archives of Toxicology. 88(12):2261-2287

المؤلفون: Jennings, Paul, Schwarz, Michael, Landesmann, Brigitte, Maggioni, Silvia, Goumenou, Marina, Bower, David, Leonard, Martin O., Wiseman, Jeffrey S.

المصدر: Archives of Toxicology. December 2014 88(12):2099-2133

المؤلفون: Thomas Exner, Catherine Mahony, Gladys Ouedraogo, Frédéric Y. Bois, Alicia Paini, Andrew Worth, Andrew White, Elisabet Berggren, Andrea-Nicole Richarz, Leo A. van Grunsven, Sofia B. Leite

المساهمون: Basic (bio-) Medical Sciences, Liver Cell Biology, Translational Liver Cell Biology

المصدر: Computational Toxicology

مصطلحات موضوعية: 0301 basic medicine, Engineering, Health, Toxicology and Mutagenesis, SERURAT-1, 010501 environmental sciences, Toxicology, 01 natural sciences, Article, 03 medical and health sciences, Chemical safety, In vitro, Component (UML), Journal Article, 0105 earth and related environmental sciences, Alternative methods, SEURAT-1, business.industry, In silico, Computer Science Applications, Reliability engineering, 030104 developmental biology, Workflow, Safety assessment, Alternative method, Ab initio, Biochemical engineering, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a58b7f66c0c15ffd3f6722eb0870aff
https://pubmed.ncbi.nlm.nih.gov/29214231

المؤلفون: Glyn Stacey, Rebecca Ceder, Vedrin Jeliazkov, Pekka Kohonen, Michael Rautenberg, Scott Miller, Glenn J. Myatt, Christoph Helma, Roland C. Grafström, Nina Jeliazkova, Jeff Wiseman, Lyn Healy, David Bower, Egon Willighagen, Silvia Maggioni, Michael Crump, Emilio Benfenati, Barry Hardy, Kevin P. Cross

المساهمون: Bioinformatica, RS: NUTRIM - R4 - Gene-environment interaction, RS: CARIM School for Cardiovascular Diseases

المصدر: Molecular Informatics; Vol 32
Molecular Informatics, 32(1), 47-63. Wiley-VCH Verlag GmbH & CO. KGaA

مصطلحات موضوعية: Representational state transfer, MECHANISM, computer.internet_protocol, Computer science, Cellular models, computer.software_genre, Repeated-dose toxicity testing, 0302 clinical medicine, Resource (project management), Wikis, Structural Biology, Predictive toxicology, Drug Discovery, 0303 health sciences, Cheminformatics, computer.file_format, Toxicogenomics, Data warehouse, 3. Good health, Computer Science Applications, ToxBank, CARBON-TETRACHLORIDE, Open standard, Data exchange, 030220 oncology & carcinogenesis, Molecular Medicine, Data mining, Web service, Semantic web, Bioinformatics, TOXICOLOGY, 03 medical and health sciences, Databases, OpenTox, VALPROIC ACID, Oxidation, HYPOXIA-INDUCIBLE FACTOR-1-ALPHA, HEPATIC TOXICITY, RDF, Semantic Web, 030304 developmental biology, DRUG-INDUCED PHOSPHOLIPIDOSIS, Redox chemistry, SEURAT-1, business.industry, Electron transport, Organic Chemistry, Reference compounds, TISSUE, CELLS, Alternative Testing Strategies, Gene expression, Software engineering, business, INDUCED HEPATOTOXICITY, computer

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8b571b466628eb415519844953a33ad
https://doi.org/10.1002/minf.201200114

المؤلفون: Harry van Steeg, Daniel Seehofer, Thomas S. Weiss, Agapios Sachinidis, Katrin Madjar, Steven Wink, Wolfgang Schmidt-Heck, Barry Hardy, Glenn J. Myatt, Marcelo Dutra Arbo, Adil Mardinoglu, Axel Oberemm, Jos C. S. Kleinjans, Marcel Leist, Regina Stöber, Mathieu Vinken, Jörg Rahnenführer, Eugen Rempel, Sylvia Escher, Dimitry Spitkovsky, Bob van de Water, Mirjam M. Schaap, Rosemarie Marchan, Agata Widera, Georg Damm, Patricio Godoy, Mirjam Luijten, Andreas K. Nussler, Jürgen Hescheler, Dragana Mitic, Rob H. Stierum, Raymond Reif, Helena Carmo, Marianna Grinberg, Tanja Waldmann, Jan G. Hengstler, Vera Rogiers, Karolina Edlund, Alfons Lampen, Wolfgang E. Thasler

المساهمون: Toxicology, Dermato-cosmetology and Pharmacognosy, Experimental in vitro toxicology and dermato-cosmetology, Publica, RS: GROW - Oncology, RS: GROW - R1 - Prevention, Toxicogenomics

المصدر: Archives of Toxicology, 12, 88, 2261-2287
Archives of Toxicology, 88(12), 2261-2287. Springer

مصطلحات موضوعية: Candidate gene, Steatosis, paracetamol, Health, Toxicology and Mutagenesis, Biomedical Innovation, RAPID - Risk Assessment Products in Development, In vivo validation, Toxicology, Toxicogenetics, Transcriptome, transcriptomics, cell stress, hepatotoxicology, Life, data base, Databases, Genetic, Biomarker identification, Cells, Cultured, transcription factor, cytochrome P450 3A4, Principal Component Analysis, quantitative analysis, Liver cell, Liver Diseases, Toxicotranscriptomics, liver cell, General Medicine, biological marker, Biochemistry, Cirrhosis, Hepatocellular cancer, real time polymerase chain reaction, toxicogenomics, liver protein, DNA microarray, Unsupervised clustering, liver disease, cytochrome P450 1A1, down regulation, Healthy Living, hepatotoxicity, isoniazid, liver cell carcinoma, allyl alcohol, Bioinformatics, liver cirrhosis, ketoconazole, galactosamine, Computational biology, Biology, Hepatotoxicity, Toxicotranscriptomics, Unsupervised clustering, In vivo validation, Steatosis, Cirrhosis, Hepatocellular cancer, Biomarker identification, Bioinformatics, SEURAT-1, Small Molecule Libraries, valproic acid, ddc:570, medicine, nonalcoholic fatty liver, Humans, chemical compound, propranolol, human, Gene, triazolam, fatty liver, SEURAT-1, Dose-Response Relationship, Drug, Microarray analysis techniques, binding site, Hepatotoxicity, medicine.disease, thyroid hormone, RNA extraction, Hepatocytes, gene expression, gene ontology, microarray analysis, ELSS - Earth, Life and Social Sciences, Steatohepatitis, mutation, Toxicogenomics, upregulation

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78d661b48f15be33654a66c975ffac55
http://resolver.tudelft.nl/uuid:dedda255-d0ac-4df8-a832-b75385363fe2

مصطلحات موضوعية: Steatosis, paracetamol, Biomedical Innovation, RAPID - Risk Assessment Products in Development, In vivo validation, transcriptomics, cell stress, Life, data base, Biomarker identification, transcription factor, cytochrome P450 3A4, quantitative analysis, Toxicotranscriptomics, liver cell, biological marker, Cirrhosis, Hepatocellular cancer, real time polymerase chain reaction, toxicogenomics, liver protein, Unsupervised clustering, liver disease, cytochrome P450 1A1, down regulation, Healthy Living, isoniazid, liver cell carcinoma, allyl alcohol, Bioinformatics, liver cirrhosis, ketoconazole, galactosamine, valproic acid, nonalcoholic fatty liver, chemical compound, propranolol, human, Life and Social Sciences, Biology, triazolam, fatty liver, SEURAT-1, binding site, Hepatotoxicity, ELSS - Earth, thyroid hormone, RNA extraction, gene expression, gene ontology, microarray analysis, mutation, upregulation

URL الوصول: https://explore.openaire.eu/search/publication?articleId=dris___00893::9eeb086a1ee0aa74a984afe31b671211
http://resolver.tudelft.nl/uuid:dedda255-d0ac-4df8-a832-b75385363fe2

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المؤلفون: Rogiers, Vera, Pauwels, Marleen, Vinken, Mathieu, Vanhaecke, Tamara

المساهمون: Consortium, Coach, Toxicology, Dermato-cosmetology and Pharmacognosy, Experimental in vitro toxicology and dermato-cosmetology

مصطلحات موضوعية: cosmetic ingredients, repeated dose toxicity, SEURAT-1, European projects, 3R alternatives

URL الوصول: https://explore.openaire.eu/search/publication?articleId=od______3848::2ff03e375fd1e9c5e7dd3067f615e4c4
https://biblio.vub.ac.be/vubir/the-seurat1-research-strategy-towards-a-more-realistic-integrated-in-vitro-strategy-for-repeated-dose-toxicity-testing-of-cosmetic-products-and-their-ingredients(40417f28-dd70-41f0-9146-091d12266fe1).html

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المؤلفون: Tamara Vanhaecke, Manon Vivier, Mathieu Vinken, Vera Rogiers, Marleen Pauwels, Gamze Ates

المساهمون: Toxicology, Dermato-cosmetology and Pharmacognosy, Experimental in vitro toxicology and dermato-cosmetology

المصدر: Vrije Universiteit Brussel

مصطلحات موضوعية: medicine.medical_specialty, Consumer Product Safety, hepatotoxicity, Health, Toxicology and Mutagenesis, media_common.quotation_subject, Context (language use), Pharmacology, Toxicology, Cosmetics, Risk Assessment, medicine, Animals, Humans, Human safety, Animal testing, Intensive care medicine, media_common, Alternative methods, SEURAT-1, Toxicity data, business.industry, cosmetics, General Medicine, SCC(NF)P/SCCS, Joint research, Liver, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc7c5bbec24313adb8c291fd5331a347
https://researchportal.vub.be/en/publications/aa74bd14-1d4a-439c-9afb-b2cbcc0adc4c