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المؤلفون: Qianqian Yang, Hailong Zhang, Nan Cui, Jinzhuo Dou, Xian Zhao, Jianxiu Yu, Ran Chen, Yanli Wang, Jian Huang, Yanmin Guo, Tianqi Liu
المصدر: Neoplasia: An International Journal for Oncology Research, Vol 21, Iss 7, Pp 676-688 (2019)
Neoplasia (New York, N.Y.)مصطلحات موضوعية: 0301 basic medicine, Original article, Cancer Research, PTM, post-translational modification, Ubiquitin-Protein Ligases, SUMO-1 Protein, Lysine, SFKs, Src family kinases, SUMO protein, SUMO, small ubiquitin-like modifier, lcsh:RC254-282, GST, glutathione S-transferase, CSK Tyrosine-Protein Kinase, 03 medical and health sciences, 0302 clinical medicine, Csk, C-terminal Src kinase, SH, Src homology, Neoplasms, PIAS, protein inhibitor of activated STAT, Cbp, Csk binding protein, Humans, Phosphorylation, biology, Kinase, Chemistry, Sumoylation, Hydrogen Peroxide, SENP1, sentrin-specific protease, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Protein Inhibitors of Activated STAT, Cell biology, Ubiquitin ligase, src-Family Kinases, 030104 developmental biology, Tumor progression, 030220 oncology & carcinogenesis, Small Ubiquitin-Related Modifier Proteins, biology.protein, Ectopic expression, Protein Processing, Post-Translational, Tyrosine kinase, Molecular Chaperones, Protein Binding
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المؤلفون: Ran Chen, Yanli Wang, Jing Wang, Jinzhuo Dou, Jianxiu Yu, Nan Cui, Hailong Zhang, Rong Deng, Tianqi Liu, Jian Huang, Xian Zhao
المصدر: Neoplasia: An International Journal for Oncology Research, Vol 19, Iss 12, Pp 961-971 (2017)
Neoplasia (New York, N.Y.)مصطلحات موضوعية: 0301 basic medicine, Models, Molecular, Cancer Research, Original article, Protein Conformation, Lysine, SUMO protein, SFKs, Src family kinases, Biology, SUMO, small ubiquitin-like modifier, lcsh:RC254-282, GST, glutathione S-transferase, Cell Line, Focal adhesion, 03 medical and health sciences, Mice, SH, Src homology, Neoplasms, Animals, Humans, SENPs, SUMO-sentrin specific proteases, Phosphorylation, Tyrosine-protein kinase CSK, CDS, coding sequence, Sumoylation, IP, immunoprecipitation, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, 030104 developmental biology, src-Family Kinases, Tumor progression, FAK, Focal adhesion kinase, Focal Adhesion Protein-Tyrosine Kinases, Mutation, Cancer research, Disease Progression, Tyrosine kinase, Proto-oncogene tyrosine-protein kinase Src
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المؤلفون: Louise Blair, Igor Stagljar, Julia Petschnigg, Igor Jurisica, Max Kotlyar, Robin Ketteler
المصدر: Journal of Molecular Biology
مصطلحات موضوعية: 0301 basic medicine, PEI, polyethylenimine, TF, transcription factor, Receptor tyrosine kinase, TACC, transforming acidic coiled-coil protein, Small hairpin RNA, ERK, extracellular signal-regulated kinase, Structural Biology, SRE, serum response element, Carcinoma, Non-Small-Cell Lung, ERBB3, Epidermal growth factor receptor, Nub, N-terminal half of ubiquitin, oncogenic signaling, Phosphorylation, RNA, Small Interfering, MOI, multiplicity of infection, GFP, green fluorescent protein, DMEM, Dulbecco's modified Eagle's medium, biology, 3. Good health, ErbB Receptors, Gene Expression Regulation, Neoplastic, two-hybrid screening, GRB2, Mitogen-Activated Protein Kinases, Microtubule-Associated Proteins, Signal Transduction, FGFR, fibroblast growth factor receptor, Cell Survival, EGFR-ex19del, EGFR-exon19 deletion, EGFR, PBS, phosphate-buffered saline, Article, 03 medical and health sciences, TKI, TK inhibitor, SH, Src homology, NSCLC, non-small cell lung cancer, Humans, Immunoprecipitation, Protein Interaction Domains and Motifs, KM, Kaplan–Meier, Protein kinase A, Molecular Biology, PI3K/AKT/mTOR pathway, non-small cell lung cancer, GO, gene ontology, EGF, epidermal growth factor, TK, tyrosine kinase, Computational Biology, EGFR-WT, EGFR-wildtype, Molecular biology, EGFR, epidermal growth factor receptor, Grb2, growth factor receptor-bound protein 2, 030104 developmental biology, HEK293 Cells, protein–protein interaction, MaMTH, mammalian membrane two-hybrid, Cancer research, biology.protein, Cyclin-dependent kinase 8, Cub, C-terminal half of ubiquitin, Gene Deletion, MAPK, mitogen-activated protein kinase, HeLa Cells
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المؤلفون: Christina Anne Mitchell, Ivan Ivetac, Wayne A. Phillips, Natalie K. Rynkiewicz, Meredith J. Layton, Kristy A. Horan
المصدر: Bioscience Reports
Bioscience Reports, Vol 34, Iss 2, p e00104 (2014)مصطلحات موضوعية: iSH2, inter-SH2, DXMS, deuterium exchange mass spectrometry, Akt, also called PKB (protein kinase B), BH, BCR-homology, 2-ME, 2-mercaptoethanol, lcsh:Life, lcsh:QR1-502, Lipid kinase activity, PI3K, Biochemistry, lcsh:Microbiology, PDGF, platelet-derived growth factor, Receptor tyrosine kinase, Madin Darby Canine Kidney Cells, GAP, GTPase-activating protein, oncogene, GST, glutathione transferase, microinjection, Cdc42, cdc42 GTP-Binding Protein, GFP, green fluorescent protein, Genetics, biology, NA, numerical aperture, HRP, horseradish peroxidase, MDCK, Madin–Darby canine kidney, PS, phosphatidylserine, Cell biology, Protein Transport, PM, plasma membrane, RTK, receptor tyrosine kinase, PI3K, phosphoinositide 3-kinase, PTEN, phosphatase and tensin homologue deleted on chromosome 10, cSH2, C-terminal SH2, Class I Phosphatidylinositol 3-Kinases, PH, pleckstrin homology, Mutation, Missense, Biophysics, P110α, S2, PI, phosphatidylinositol, pY, phosphotyrosine, Membrane Lipids, nSH2, N-terminal SH2, PIP3, phosphoinositide-3,4,5-trisphosphate, Dogs, SH, Src homology, Animals, Humans, PIP2, phosphoinositide-4,5-disphosphate, Molecular Biology, Protein kinase B, Microinjection, PI3K/AKT/mTOR pathway, EGF, epidermal growth factor, Original Paper, Phosphoinositide 3-kinase, Cell Membrane, PIK3CA, Cell Biology, mutation, PTEN, RTK - receptor tyrosine kinase, SH2 - Src homology 2, Subcellular localization, lcsh:QH501-531, Amino Acid Substitution, biology.protein, iMMEC, immortalized mouse mammary epithelial cells, Proto-Oncogene Proteins c-akt, DAPI, 4′,6-diamidino-2-phenylindole
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94e57cf0b25e79fca314f084b77ffb8c
https://www.bib.irb.hr/1049295 -
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المؤلفون: Jolanta Wiejak, Simon P. Mackay, Julia Dunlop, Stephen J. Yarwood
المصدر: Biochemical Journal
مصطلحات موضوعية: PDE, phosphodiesterase, STAT3, signal transducer and activator of transcription 3, Suppressor of Cytokine Signaling Proteins, ACC, acetyl-CoA carboxylase, AMP-Activated Protein Kinases, Biochemistry, DMEM, Dulbecco’s modified Eagle’s medium, Mice, HUVEC, human umbilical vein endothelial cell, Chlorocebus aethiops, suppressor of cytokine signalling 3 (SOCS3), Cytokine Receptor gp130, SOCS3, Promoter Regions, Genetic, STAT3, Cells, Cultured, flavanoid, Regulation of gene expression, RT, reverse transcription, Anti-Inflammatory Agents, Non-Steroidal, digestive, oral, and skin physiology, MCP-1, monocyte chemotactic protein-1, Recombinant Proteins, TNFα, tumour necrosis factor α, Signal transduction, JAK, Janus kinase, IL-6R, IL-6 receptor, Research Article, Signal Transduction, STAT3 Transcription Factor, interleukin-6 (IL-6), Biology, ERK, extracellular-signal-regulated kinase, Suppressor of cytokine signalling, Cell Line, HEK, human embryonic kidney, SH, Src homology, PKC, protein kinase C, Human Umbilical Vein Endothelial Cells, Animals, Humans, Protein Kinase Inhibitors, Molecular Biology, Flavonoids, SOCS, suppressor of cytokine signalling, Interleukin-6, Cell Biology, IL, interleukin, CK2, casein kinase 2, AMPK, AMP-activated protein kinase, Gene Expression Regulation, Suppressor of Cytokine Signaling 3 Protein, MEK, MAPK/ERK kinase, Interleukin-6 Receptor alpha Subunit, gene expression, biology.protein, Cancer research, STAT protein, Janus kinase/signal transducer and activator of transcription (JAK/STAT), Mutant Proteins, Endothelium, Vascular, VEC, vascular endothelial cell, Janus kinase, VASP, vasodilator-stimulated phosphoprotein, MAPK, mitogen-activated protein kinase
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b8c8561f684f5facbaddda304a58fda
https://eprints.gla.ac.uk/82778/1/82778.pdf -
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المؤلفون: Björn Öbrink
المصدر: Current Opinion in Cell Biology
مصطلحات موضوعية: Calmodulin, Molecular Sequence Data, ITAM immunoreceptor tyrosine-based activation motif, Protein tyrosine phosphatase, ITIM immunoreceptor tyrosine-based inhibition motif, Article, IgSF Ig gene superfamily, S short, Carcinoembryonic antigen, Nectin, CEA carcinoembryonic antigen, PTP protein tyrosine phosphatase, CGM CEA gene family member, Animals, Humans, Ig immunoglobulin, Tumor growth, Amino Acid Sequence, Cell adhesion, C-CAM cell—cell adhesion molecule, Peptide sequence, SIRP signal-regulatory protein, biology, Cell adhesion molecule, L long, Cell Biology, PTK protein tyrosine kinase, SH Src homology, Bgp biliary glycoprotein in mouse, Carcinoembryonic Antigen, Biochemistry, biology.protein, BGP biliary glycoprotein in man, GPI glycosylphosphatidylinositol, NCA nonspecific cross-reactive antigen, SHP SH2-domain-containing PTP, Cell Adhesion Molecules, Signal Transduction
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