المؤلفون: J Yang, K Bergdorf, C Yan, W Luo, SC Chen, D Ayers, Q Liu, X Liu, M Boothby, SM Groves, AN Oleskie, X Zhang, DY Maeda, JA Zebala, V Quaranta, A Richmond

المصدر: bioRxiv

مصطلحات موضوعية: Article

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74263a5e1245e1eb84bf21d66a6f9030
https://europepmc.org/articles/PMC9980137/

المؤلفون: Groves SM; Department of Pharmacology, Vanderbilt University, Nashville, TN, United States., Quaranta V; Department of Pharmacology, Vanderbilt University, Nashville, TN, United States.; Department of Biochemistry, Vanderbilt University, Nashville, TN, United States.

المصدر: Frontiers in network physiology [Front Netw Physiol] 2023 Sep 04; Vol. 3, pp. 1225736. Date of Electronic Publication: 2023 Sep 04 (Print Publication: 2023).

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Frontiers Media S.A Country of Publication: Switzerland NLM ID: 9918334487406676 Publication Model: eCollection Cited Medium: Internet ISSN: 2674-0109 (Electronic) Linking ISSN: 26740109 NLM ISO Abbreviation: Front Netw Physiol Subsets: PubMed not MEDLINE

المؤلفون: Yang J; TVHS Department of Veterans Affairs, Nashville, TN, 37212, USA.; Department of Pharmacology, Vanderbilt University School of Medicine, Nashville, TN, 37240, USA., Bergdorf K; TVHS Department of Veterans Affairs, Nashville, TN, 37212, USA.; Department of Pharmacology, Vanderbilt University School of Medicine, Nashville, TN, 37240, USA., Yan C; TVHS Department of Veterans Affairs, Nashville, TN, 37212, USA.; Department of Pharmacology, Vanderbilt University School of Medicine, Nashville, TN, 37240, USA., Luo W; TVHS Department of Veterans Affairs, Nashville, TN, 37212, USA.; Department of Pharmacology, Vanderbilt University School of Medicine, Nashville, TN, 37240, USA., Chen SC; Department of Biostatistics, Vanderbilt University Medical Center, Nashville, TN, 37203-1742, USA., Ayers GD; Department of Biostatistics, Vanderbilt University Medical Center, Nashville, TN, 37203-1742, USA., Liu Q; Department of Biostatistics, Vanderbilt University Medical Center, Nashville, TN, 37203-1742, USA., Liu X; Department of Biostatistics, Vanderbilt University Medical Center, Nashville, TN, 37203-1742, USA., Boothby M; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN, 37232, USA., Weiss VL; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN, 37232, USA., Groves SM; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN, 37232, USA., Oleskie AN; Department of Pharmacology, Vanderbilt University School of Medicine, Nashville, TN, 37240, USA., Zhang X; Department of Genomic Medicine, MD Anderson Cancer Center, University of Texas, Houston, TX, 77030, USA., Maeda DY; Syntrix Pharmaceuticals, Auburn, WA, 98001, USA., Zebala JA; Syntrix Pharmaceuticals, Auburn, WA, 98001, USA., Quaranta V; Department of Pharmacology, Vanderbilt University School of Medicine, Nashville, TN, 37240, USA.; Department of Biochemistry, Vanderbilt University, TN, 37240, Nashville, USA., Richmond A; TVHS Department of Veterans Affairs, Nashville, TN, 37212, USA. ann.richmond@vanderbilt.edu.; Department of Pharmacology, Vanderbilt University School of Medicine, Nashville, TN, 37240, USA. ann.richmond@vanderbilt.edu.

المصدر: Molecular cancer [Mol Cancer] 2023 Jun 03; Vol. 22 (1), pp. 92. Date of Electronic Publication: 2023 Jun 03.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 101147698 Publication Model: Electronic Cited Medium: Internet ISSN: 1476-4598 (Electronic) Linking ISSN: 14764598 NLM ISO Abbreviation: Mol Cancer Subsets: MEDLINE

مواضيع طبية MeSH: Melanoma*/metabolism , Proto-Oncogene Proteins B-raf*/genetics , Receptors, Interleukin-8B*/genetics , Receptors, Interleukin-8B*/metabolism, Animals ; Mice ; Carcinogenesis/genetics ; Cell Line, Tumor ; Cell Transformation, Neoplastic ; Tumor Microenvironment

المؤلفون: Groves SM; Department of Biochemistry, Vanderbilt University, Nashville, TN 37235, USA., Panchy N; Department of Biochemistry & Cellular and Molecular Biology, The University of Tennessee, Knoxville, TN 37996, USA., Tyson DR; Department of Biochemistry, Vanderbilt University, Nashville, TN 37235, USA.; Department of Pharmacology, Vanderbilt University, Nashville, TN 37235, USA., Harris LA; Department of Biomedical Engineering, University of Arkansas, Fayetteville, AR 72701, USA.; Interdisciplinary Graduate Program in Cell and Molecular Biology, University of Arkansas, Fayetteville, AR 72701, USA.; Cancer Biology Program, Winthrop P. Rockefeller Cancer Institute, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA., Quaranta V; Department of Biochemistry, Vanderbilt University, Nashville, TN 37235, USA.; Department of Pharmacology, Vanderbilt University, Nashville, TN 37235, USA., Hong T; Department of Biochemistry & Cellular and Molecular Biology, The University of Tennessee, Knoxville, TN 37996, USA.; National Institute for Mathematical and Biological Synthesis, Knoxville, TN 37996, USA.

المصدر: Cancers [Cancers (Basel)] 2023 Feb 25; Vol. 15 (5). Date of Electronic Publication: 2023 Feb 25.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101526829 Publication Model: Electronic Cited Medium: Print ISSN: 2072-6694 (Print) Linking ISSN: 20726694 NLM ISO Abbreviation: Cancers (Basel) Subsets: PubMed not MEDLINE

المؤلفون: Groves SM; Department of Biochemistry, Vanderbilt University, Nashville, TN 37235, USA., Ildefonso GV; Department of Biochemistry, Vanderbilt University, Nashville, TN 37235, USA., McAtee CO; Department of Cell and Developmental Biology, Vanderbilt University, Nashville, TN 37235, USA., Ozawa PMM; Department of Cell and Developmental Biology, Vanderbilt University, Nashville, TN 37235, USA., Ireland AS; Department of Oncological Sciences, Huntsman Cancer Institute, University of Utah, Salt Lake City, UT 84112, USA., Stauffer PE; Department of Biochemistry, Vanderbilt University, Nashville, TN 37235, USA., Wasdin PT; Department of Biochemistry, Vanderbilt University, Nashville, TN 37235, USA., Huang X; Utah Center for Genetic Discovery, Eccles Institute of Human Genetics, University of Utah, Salt Lake City, UT 84112, USA., Qiao Y; Utah Center for Genetic Discovery, Eccles Institute of Human Genetics, University of Utah, Salt Lake City, UT 84112, USA., Lim JS; Department of Pediatrics and Genetics, Stanford University, Stanford, CA 94305, USA., Bader J; Department of Pathology, Microbiology, and Immunology, Vanderbilt Center for Immunobiology, Vanderbilt University Medical Center, Nashville, TN 37232, USA., Liu Q; Department of Biostatistics and Center for Quantitative Sciences, Vanderbilt University Medical Center, Nashville, TN 37235, USA., Simmons AJ; Epithelial Biology Center and Department of Cell and Developmental Biology, Vanderbilt University School of Medicine, Nashville, TN 37235, USA., Lau KS; Epithelial Biology Center and Department of Cell and Developmental Biology, Vanderbilt University School of Medicine, Nashville, TN 37235, USA., Iams WT; Division of Hematology-Oncology, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN 37235, USA., Hardin DP; Department of Mathematics and Department of Biomedical Informatics, Vanderbilt University, Nashville, TN 37235, USA., Saff EB; Department of Mathematics, Vanderbilt University, Nashville, TN 37235, USA., Holmes WR; Department of Mathematics, Vanderbilt University, Nashville, TN 37235, USA; Department of Physics, Vanderbilt University, Nashville, TN 37235, USA., Tyson DR; Department of Biochemistry, Vanderbilt University, Nashville, TN 37235, USA., Lovly CM; Department of Mathematics and Department of Biomedical Informatics, Vanderbilt University, Nashville, TN 37235, USA; Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, TN 37235, USA., Rathmell JC; Department of Pathology, Microbiology, and Immunology, Vanderbilt Center for Immunobiology, Vanderbilt University Medical Center, Nashville, TN 37232, USA., Marth G; Utah Center for Genetic Discovery, Eccles Institute of Human Genetics, University of Utah, Salt Lake City, UT 84112, USA., Sage J; Department of Pediatrics and Genetics, Stanford University, Stanford, CA 94305, USA., Oliver TG; Department of Oncological Sciences, Huntsman Cancer Institute, University of Utah, Salt Lake City, UT 84112, USA., Weaver AM; Department of Cell and Developmental Biology, Vanderbilt University, Nashville, TN 37235, USA; Department of Pathology, Microbiology, and Immunology, Vanderbilt University, Nashville, TN 37235, USA., Quaranta V; Department of Biochemistry, Vanderbilt University, Nashville, TN 37235, USA. Electronic address: vito.quaranta@vanderbilt.edu.

المصدر: Cell systems [Cell Syst] 2022 Sep 21; Vol. 13 (9), pp. 690-710.e17. Date of Electronic Publication: 2022 Aug 17.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101656080 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2405-4720 (Electronic) Linking ISSN: 24054712 NLM ISO Abbreviation: Cell Syst Subsets: MEDLINE

مواضيع طبية MeSH: Lung Neoplasms*/genetics , Lung Neoplasms*/pathology , Small Cell Lung Carcinoma*/genetics , Small Cell Lung Carcinoma*/metabolism , Small Cell Lung Carcinoma*/pathology, Cell Plasticity ; Humans

المؤلفون: Thomas PL; Department of Microbiology, Immunology & Physiology, School of Medicine, Meharry Medical College, Nashville, Tennessee; School of Graduate Studies & Research, Meharry Medical College, Nashville, Tennessee., Groves SM; Department of Biochemistry, Vanderbilt University, Nashville, Tennessee., Zhang YK; Division of Hematology-Oncology, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee., Li J; Department of Biostatistics, Vanderbilt University Medical Center, Nashville, Tennessee., Gonzalez-Ericsson P; Breast Cancer Research Program, Vanderbilt Ingram Cancer Center, Vanderbilt University, Nashville, Tennessee., Sivagnanam S; Department of Cell, Developmental and Cancer Biology, Oregon Health & Science University, Portland, Oregon; Knight Cancer Institute, Oregon Health & Science University, Portland, Oregon., Betts CB; Department of Cell, Developmental and Cancer Biology, Oregon Health & Science University, Portland, Oregon; Knight Cancer Institute, Oregon Health & Science University, Portland, Oregon., Chen HC; Department of Biostatistics, Vanderbilt University Medical Center, Nashville, Tennessee., Liu Q; Department of Biostatistics, Vanderbilt University Medical Center, Nashville, Tennessee., Lowe C; Department of Pathology, Immunology and Microbiology, Vanderbilt University Medical Center, Nashville, Tennessee., Chen H; Department of Biostatistics, Vanderbilt University Medical Center, Nashville, Tennessee., Boyd KL; Department of Pathology, Immunology and Microbiology, Vanderbilt University Medical Center, Nashville, Tennessee., Kopparapu PR; Division of Hematology-Oncology, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee., Yan Y; Division of Hematology-Oncology, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee., Coussens LM; Department of Cell, Developmental and Cancer Biology, Oregon Health & Science University, Portland, Oregon; Knight Cancer Institute, Oregon Health & Science University, Portland, Oregon., Quaranta V; Department of Biochemistry, Vanderbilt University, Nashville, Tennessee., Tyson DR; Department of Biochemistry, Vanderbilt University, Nashville, Tennessee., Iams W; Division of Hematology-Oncology, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee., Lovly CM; School of Graduate Studies & Research, Meharry Medical College, Nashville, Tennessee; Division of Hematology-Oncology, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee; Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, Tennessee. Electronic address: christine.lovly@vumc.org.

المصدر: Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer [J Thorac Oncol] 2021 Jul; Vol. 16 (7), pp. 1211-1223. Date of Electronic Publication: 2021 Apr 08.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 101274235 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1556-1380 (Electronic) Linking ISSN: 15560864 NLM ISO Abbreviation: J Thorac Oncol Subsets: MEDLINE

مواضيع طبية MeSH: Lung Neoplasms*/drug therapy , Lung Neoplasms*/genetics , Small Cell Lung Carcinoma*/drug therapy , Small Cell Lung Carcinoma*/genetics, B7-H1 Antigen ; Humans ; Immunotherapy ; Progression-Free Survival

المؤلفون: Olsen RR; Department of Oncological Sciences, Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah 84112, USA., Ireland AS; Department of Oncological Sciences, Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah 84112, USA., Kastner DW; Department of Oncological Sciences, Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah 84112, USA., Groves SM; Department of Biochemistry, Vanderbilt University, Nashville, Tennessee 37212, USA., Spainhower KB; Department of Oncological Sciences, Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah 84112, USA., Pozo K; Department of Neuroscience, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA., Kelenis DP; Department of Neuroscience, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA., Whitney CP; Department of Oncological Sciences, Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah 84112, USA., Guthrie MR; Department of Oncological Sciences, Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah 84112, USA., Wait SJ; Department of Oncological Sciences, Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah 84112, USA., Soltero D; Department of Oncological Sciences, Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah 84112, USA., Witt BL; Department of Pathology, University of Utah, Salt Lake City, Utah 84112, USA.; ARUP Laboratories at University of Utah, Salt Lake City, Utah 84108, USA., Quaranta V; Department of Biochemistry, Vanderbilt University, Nashville, Tennessee 37212, USA., Johnson JE; Department of Neuroscience, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.; Hamon Center for Therapeutic Oncology Research, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA., Oliver TG; Department of Oncological Sciences, Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah 84112, USA.

المصدر: Genes & development [Genes Dev] 2021 Jun; Vol. 35 (11-12), pp. 847-869. Date of Electronic Publication: 2021 May 20.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Cold Spring Harbor Laboratory Press Country of Publication: United States NLM ID: 8711660 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1549-5477 (Electronic) Linking ISSN: 08909369 NLM ISO Abbreviation: Genes Dev Subsets: MEDLINE

مواضيع طبية MeSH: Basic Helix-Loop-Helix Transcription Factors/*genetics , Basic Helix-Loop-Helix Transcription Factors/*metabolism , SOX9 Transcription Factor/*genetics , Small Cell Lung Carcinoma/*genetics, Animals ; Animals, Genetically Modified ; Disease Models, Animal ; Gene Expression Regulation, Neoplastic/genetics ; Humans ; Mice ; Neural Crest/cytology ; Small Cell Lung Carcinoma/physiopathology ; Stem Cells/cytology

المؤلفون: Gay CM; Department of Thoracic/Head & Neck Medical Oncology, the University of Texas MD Anderson Cancer Center, Houston, TX, USA., Stewart CA; Department of Thoracic/Head & Neck Medical Oncology, the University of Texas MD Anderson Cancer Center, Houston, TX, USA., Park EM; Department of Thoracic/Head & Neck Medical Oncology, the University of Texas MD Anderson Cancer Center, Houston, TX, USA., Diao L; Department of Bioinformatics and Computational Biology, the University of Texas MD Anderson Cancer Center, Houston, TX, USA., Groves SM; Department of Biochemistry, Vanderbilt University Medical Center, Nashville, TN, USA., Heeke S; Department of Thoracic/Head & Neck Medical Oncology, the University of Texas MD Anderson Cancer Center, Houston, TX, USA., Nabet BY; Department of Oncology Biomarker Development, Genentech Inc., South San Francisco CA, USA., Fujimoto J; Department of Translational Molecular Pathology, the University of Texas MD Anderson Cancer Center, Houston, TX, USA., Solis LM; Department of Translational Molecular Pathology, the University of Texas MD Anderson Cancer Center, Houston, TX, USA., Lu W; Department of Translational Molecular Pathology, the University of Texas MD Anderson Cancer Center, Houston, TX, USA., Xi Y; Department of Bioinformatics and Computational Biology, the University of Texas MD Anderson Cancer Center, Houston, TX, USA., Cardnell RJ; Department of Thoracic/Head & Neck Medical Oncology, the University of Texas MD Anderson Cancer Center, Houston, TX, USA., Wang Q; Department of Bioinformatics and Computational Biology, the University of Texas MD Anderson Cancer Center, Houston, TX, USA., Fabbri G; AstraZeneca, Waltham, MA, USA., Cargill KR; Department of Thoracic/Head & Neck Medical Oncology, the University of Texas MD Anderson Cancer Center, Houston, TX, USA., Vokes NI; Department of Thoracic/Head & Neck Medical Oncology, the University of Texas MD Anderson Cancer Center, Houston, TX, USA., Ramkumar K; Department of Thoracic/Head & Neck Medical Oncology, the University of Texas MD Anderson Cancer Center, Houston, TX, USA., Zhang B; Department of Thoracic/Head & Neck Medical Oncology, the University of Texas MD Anderson Cancer Center, Houston, TX, USA., Della Corte CM; Department of Precision Medicine, Oncology Division, University of Campania 'Luigi Vanvitelli', Naples, Italy., Robson P; The Jackson Laboratory for Genomic Medicine, Farmington, CT, USA., Swisher SG; Department of Thoracic and Cardiovascular Surgery, the University of Texas MD Anderson Cancer Center, Houston, TX, USA., Roth JA; Department of Thoracic and Cardiovascular Surgery, the University of Texas MD Anderson Cancer Center, Houston, TX, USA., Glisson BS; Department of Thoracic/Head & Neck Medical Oncology, the University of Texas MD Anderson Cancer Center, Houston, TX, USA., Shames DS; Department of Oncology Biomarker Development, Genentech Inc., South San Francisco CA, USA., Wistuba II; Department of Translational Molecular Pathology, the University of Texas MD Anderson Cancer Center, Houston, TX, USA., Wang J; Department of Bioinformatics and Computational Biology, the University of Texas MD Anderson Cancer Center, Houston, TX, USA., Quaranta V; Department of Biochemistry, Vanderbilt University Medical Center, Nashville, TN, USA., Minna J; Department of Internal Medicine and Simmons Cancer Center, the University of Texas Southwestern Medical Center, Dallas, TX, USA., Heymach JV; Department of Thoracic/Head & Neck Medical Oncology, the University of Texas MD Anderson Cancer Center, Houston, TX, USA., Byers LA; Department of Thoracic/Head & Neck Medical Oncology, the University of Texas MD Anderson Cancer Center, Houston, TX, USA. Electronic address: lbyers@mdanderson.org.

المصدر: Cancer cell [Cancer Cell] 2021 Mar 08; Vol. 39 (3), pp. 346-360.e7. Date of Electronic Publication: 2021 Jan 21.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101130617 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-3686 (Electronic) Linking ISSN: 15356108 NLM ISO Abbreviation: Cancer Cell Subsets: MEDLINE

مواضيع طبية MeSH: Immunity/*immunology , Lung Neoplasms/*immunology , Small Cell Lung Carcinoma/*immunology , Transcription Factors/*immunology, Animals ; Cell Line, Tumor ; Cisplatin/pharmacology ; Female ; Gene Expression Regulation, Neoplastic/drug effects ; Gene Expression Regulation, Neoplastic/immunology ; Humans ; Immunity/drug effects ; Lung Neoplasms/drug therapy ; Mice, Nude ; Prognosis ; Small Cell Lung Carcinoma/drug therapy ; Mice

المؤلفون: Wooten DJ; Department of Physics, The Pennsylvania State University, University Park, Pennsylvania, United States of America.; Department of Biochemistry, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America., Groves SM; Department of Biochemistry, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America., Tyson DR; Department of Biochemistry, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America., Liu Q; Departments of Biomedical Informatics and Biostatistics, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America., Lim JS; Departments of Pediatrics and Genetics, Stanford University, Stanford, California, United States of America., Albert R; Department of Physics, The Pennsylvania State University, University Park, Pennsylvania, United States of America., Lopez CF; Department of Biochemistry, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America., Sage J; Departments of Pediatrics and Genetics, Stanford University, Stanford, California, United States of America., Quaranta V; Department of Biochemistry, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America.

المصدر: PLoS computational biology [PLoS Comput Biol] 2019 Oct 31; Vol. 15 (10), pp. e1007343. Date of Electronic Publication: 2019 Oct 31 (Print Publication: 2019).

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238922 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7358 (Electronic) Linking ISSN: 1553734X NLM ISO Abbreviation: PLoS Comput Biol Subsets: MEDLINE

مواضيع طبية MeSH: Small Cell Lung Carcinoma/*classification , Small Cell Lung Carcinoma/*metabolism, Algorithms ; Animals ; Basic Helix-Loop-Helix Transcription Factors/metabolism ; Bayes Theorem ; Cell Line, Tumor ; Cluster Analysis ; Databases, Genetic ; Drug Resistance, Neoplasm ; Gene Expression ; Gene Expression Regulation, Neoplastic/genetics ; Gene Ontology ; Gene Regulatory Networks/genetics ; Humans ; Mice ; Models, Theoretical ; Systems Analysis ; Transcription Factors/metabolism