المؤلفون: Tachikawa H; Department of Pharmaceutical Sciences, Tokyo Metropolitan Institute of Public Health, Tokyo, Japan. Electronic address: Hajime_Tachikawa@member.metro.tokyo.jp., Nishiyama R; Department of Pharmaceutical Sciences, Tokyo Metropolitan Institute of Public Health, Tokyo, Japan., Kosugi Y; Department of Pharmaceutical Sciences, Tokyo Metropolitan Institute of Public Health, Tokyo, Japan., Ichikawa-Kaji Y; Department of Pharmaceutical Sciences, Tokyo Metropolitan Institute of Public Health, Tokyo, Japan., Uemura N; Department of Pharmaceutical Sciences, Tokyo Metropolitan Institute of Public Health, Tokyo, Japan., Moriuchi Y; Department of Pharmaceutical Sciences, Tokyo Metropolitan Institute of Public Health, Tokyo, Japan., Moriyasu T; Tokyo Food Sanitation Association Food Research Laboratory, Tokyo, Japan., Suzuki T; Department of Pharmaceutical Sciences, Tokyo Metropolitan Institute of Public Health, Tokyo, Japan., Inomata A; Department of Pharmaceutical Sciences, Tokyo Metropolitan Institute of Public Health, Tokyo, Japan.

المصدر: Journal of pharmaceutical and biomedical analysis [J Pharm Biomed Anal] 2024 Aug 15; Vol. 246, pp. 116226. Date of Electronic Publication: 2024 May 15.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Science Country of Publication: England NLM ID: 8309336 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-264X (Electronic) Linking ISSN: 07317085 NLM ISO Abbreviation: J Pharm Biomed Anal Subsets: MEDLINE

مواضيع طبية MeSH: Phosphodiesterase 5 Inhibitors*/chemistry , Phosphodiesterase 5 Inhibitors*/analysis , Phosphodiesterase 5 Inhibitors*/pharmacology , Magnetic Resonance Spectroscopy*/methods , Temperature*, Crystallography, X-Ray/methods ; Tandem Mass Spectrometry/methods ; Cyclic Nucleotide Phosphodiesterases, Type 5/metabolism ; Cyclic Nucleotide Phosphodiesterases, Type 5/chemistry ; Piperazines/chemistry ; Piperazines/pharmacology ; Piperazines/analysis

المؤلفون: Pereira DA; Laboratory of Pharmacology, São Francisco University Medical School, Bragança Paulista, SP, Brazil (D.A.P., F.H.S.); Universidade Federal de São Paulo, Escola Paulista de Medicina, Department of Pharmacology, São Paulo, SP, Brazil (F.B.C.); Hematology and Hemotherapy Center, University of Campinas, Campinas, SP, Brazil (F.F.C.); and The James Buchanan Brady Urological Institute and Department of Urology, The Johns Hopkins School of Medicine, Baltimore, Maryland (A.L.B.)., Calmasini FB; Laboratory of Pharmacology, São Francisco University Medical School, Bragança Paulista, SP, Brazil (D.A.P., F.H.S.); Universidade Federal de São Paulo, Escola Paulista de Medicina, Department of Pharmacology, São Paulo, SP, Brazil (F.B.C.); Hematology and Hemotherapy Center, University of Campinas, Campinas, SP, Brazil (F.F.C.); and The James Buchanan Brady Urological Institute and Department of Urology, The Johns Hopkins School of Medicine, Baltimore, Maryland (A.L.B.)., Costa FF; Laboratory of Pharmacology, São Francisco University Medical School, Bragança Paulista, SP, Brazil (D.A.P., F.H.S.); Universidade Federal de São Paulo, Escola Paulista de Medicina, Department of Pharmacology, São Paulo, SP, Brazil (F.B.C.); Hematology and Hemotherapy Center, University of Campinas, Campinas, SP, Brazil (F.F.C.); and The James Buchanan Brady Urological Institute and Department of Urology, The Johns Hopkins School of Medicine, Baltimore, Maryland (A.L.B.)., Burnett AL; Laboratory of Pharmacology, São Francisco University Medical School, Bragança Paulista, SP, Brazil (D.A.P., F.H.S.); Universidade Federal de São Paulo, Escola Paulista de Medicina, Department of Pharmacology, São Paulo, SP, Brazil (F.B.C.); Hematology and Hemotherapy Center, University of Campinas, Campinas, SP, Brazil (F.F.C.); and The James Buchanan Brady Urological Institute and Department of Urology, The Johns Hopkins School of Medicine, Baltimore, Maryland (A.L.B.)., Silva FH; Laboratory of Pharmacology, São Francisco University Medical School, Bragança Paulista, SP, Brazil (D.A.P., F.H.S.); Universidade Federal de São Paulo, Escola Paulista de Medicina, Department of Pharmacology, São Paulo, SP, Brazil (F.B.C.); Hematology and Hemotherapy Center, University of Campinas, Campinas, SP, Brazil (F.F.C.); and The James Buchanan Brady Urological Institute and Department of Urology, The Johns Hopkins School of Medicine, Baltimore, Maryland (A.L.B.) fabio.hsilva@usf.edu.br fabiohsilva87@gmail.com.

المصدر: The Journal of pharmacology and experimental therapeutics [J Pharmacol Exp Ther] 2024 Jul 18; Vol. 390 (2), pp. 203-212. Date of Electronic Publication: 2024 Jul 18.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: American Society for Pharmacology and Experimental Therapeutics Country of Publication: United States NLM ID: 0376362 Publication Model: Electronic Cited Medium: Internet ISSN: 1521-0103 (Electronic) Linking ISSN: 00223565 NLM ISO Abbreviation: J Pharmacol Exp Ther Subsets: MEDLINE

مواضيع طبية MeSH: Priapism*/etiology , Priapism*/drug therapy , Priapism*/metabolism , Anemia, Sickle Cell*/drug therapy , Anemia, Sickle Cell*/complications , Anemia, Sickle Cell*/metabolism , Nitric Oxide*/metabolism , Cyclic Nucleotide Phosphodiesterases, Type 5*/metabolism, Humans ; Male ; Animals ; Cyclic GMP/metabolism ; Phosphodiesterase 5 Inhibitors/therapeutic use ; Phosphodiesterase 5 Inhibitors/pharmacology

المؤلفون: Gottlieb LA; Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark.

المصدر: Journal of cardiovascular pharmacology [J Cardiovasc Pharmacol] 2024 Jul 01; Vol. 84 (1), pp. 32-33. Date of Electronic Publication: 2024 Jul 01.

نوع المنشور: Editorial; Journal Article

بيانات الدورية: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 7902492 Publication Model: Electronic Cited Medium: Internet ISSN: 1533-4023 (Electronic) Linking ISSN: 01602446 NLM ISO Abbreviation: J Cardiovasc Pharmacol Subsets: MEDLINE

مواضيع طبية MeSH: Sleep Apnea, Obstructive*/drug therapy , Sleep Apnea, Obstructive*/physiopathology , Phosphodiesterase 5 Inhibitors*/therapeutic use , Phosphodiesterase 5 Inhibitors*/pharmacology, Humans ; Treatment Outcome ; Animals ; Cyclic Nucleotide Phosphodiesterases, Type 5/metabolism

المؤلفون: Saikia Q; Department of Zoology, Mangaldai College, Mangaldai, Assam 784125, India., Adhikari K; Department of Zoology, Tihu College, Tihu, Assam 781371, India., Sanjeev A; ACTREC, Sector 22, Utsav Chowk - CISF Rd, Owe Camp, Kharghar, Navi Mumbai, Maharashtra 410210, India., Hazarika A; Tyagbir Hem Baruah College, Jamugurihat, Sonitpur, Assam 784189, India., Sarma K; Department of Computational Biology and Biotechnology, Mahapurusha Srimanta Sankardeva Viswavidyalaya (Guwahati Unit), Rupnagar, Guwahati 781032, India.

المصدر: The Journal of pharmacy and pharmacology [J Pharm Pharmacol] 2024 Aug 02; Vol. 76 (8), pp. 1065-1077.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Oxford University Press Country of Publication: England NLM ID: 0376363 Publication Model: Print Cited Medium: Internet ISSN: 2042-7158 (Electronic) Linking ISSN: 00223573 NLM ISO Abbreviation: J Pharm Pharmacol Subsets: MEDLINE

مواضيع طبية MeSH: Chalcones*/pharmacology , Chalcones*/pharmacokinetics , Erectile Dysfunction*/drug therapy , Nitric Oxide Synthase Type III*/metabolism , Cyclic Nucleotide Phosphodiesterases, Type 5*/metabolism, Animals ; Male ; Mice ; Sildenafil Citrate/pharmacology ; Phosphodiesterase 5 Inhibitors/pharmacology ; Molecular Docking Simulation ; RNA, Messenger/metabolism ; Molecular Dynamics Simulation ; Paroxetine/pharmacology ; Sexual Behavior, Animal/drug effects ; Disease Models, Animal

المؤلفون: Lippner DS; Department of Biology, The Johns Hopkins University, Baltimore, Maryland, USA., Xu J; Monell Chemical Senses Center, Philadelphia, Pennsylvania, USA., Ma S; Department of Biology, The Johns Hopkins University, Baltimore, Maryland, USA., Reisert J; Monell Chemical Senses Center, Philadelphia, Pennsylvania, USA., Zhao H; Department of Biology, The Johns Hopkins University, Baltimore, Maryland, USA.

المصدر: Genesis (New York, N.Y. : 2000) [Genesis] 2024 Jun; Vol. 62 (3), pp. e23603.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Wiley-Liss Country of Publication: United States NLM ID: 100931242 Publication Model: Print Cited Medium: Internet ISSN: 1526-968X (Electronic) Linking ISSN: 1526954X NLM ISO Abbreviation: Genesis Subsets: MEDLINE

مواضيع طبية MeSH: Vomeronasal Organ*/metabolism , Cyclic Nucleotide Phosphodiesterases, Type 5*/metabolism , Cyclic Nucleotide Phosphodiesterases, Type 5*/genetics, Animals ; Mice ; Male ; Phosphodiesterase 5 Inhibitors/pharmacology ; Tadalafil/pharmacology ; Sildenafil Citrate/pharmacology ; Pheromones/metabolism ; Aggression/physiology ; Female ; Mice, Inbred C57BL

المؤلفون: Liu J; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China., Zhang X; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China., Chen G; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China; University of Chinese Academy of Sciences, Beijing, 100049, China., Shao Q; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China., Zou Y; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China., Li Z; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China; University of Chinese Academy of Sciences, Beijing, 100049, China., Su H; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China., Li M; Shanghai Synchrotron Radiation Facility, Shanghai Advanced Research Institute, Chinese Academy of Sciences, Shanghai, 201210, China., Xu Y; School of Pharmaceutical Science and Technology, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou, 310024, China; State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai, 201203, China; University of Chinese Academy of Sciences, Beijing, 100049, China. Electronic address: ycxu@simm.ac.cn.

المصدر: European journal of medicinal chemistry [Eur J Med Chem] 2023 Dec 15; Vol. 262, pp. 115893. Date of Electronic Publication: 2023 Oct 23.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 0420510 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1768-3254 (Electronic) Linking ISSN: 02235234 NLM ISO Abbreviation: Eur J Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Phosphodiesterase 5 Inhibitors*/chemistry , Phosphodiesterase 4 Inhibitors*/pharmacology, Cyclic Nucleotide Phosphodiesterases, Type 4 ; Drug Repositioning ; Cyclic Nucleotide Phosphodiesterases, Type 5/metabolism

المؤلفون: Nilsson D; Centre for Urology Research, Faculty of Health Sciences and Medicine, Bond University, Gold Coast, Queensland, 4226, Australia., Chess-Williams R; Centre for Urology Research, Faculty of Health Sciences and Medicine, Bond University, Gold Coast, Queensland, 4226, Australia., Sellers D; Centre for Urology Research, Faculty of Health Sciences and Medicine, Bond University, Gold Coast, Queensland, 4226, Australia. Electronic address: dsellers@bond.edu.au.

المصدر: European journal of pharmacology [Eur J Pharmacol] 2023 Dec 05; Vol. 960, pp. 176152. Date of Electronic Publication: 2023 Nov 02.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 1254354 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0712 (Electronic) Linking ISSN: 00142999 NLM ISO Abbreviation: Eur J Pharmacol Subsets: MEDLINE

مواضيع طبية MeSH: Phosphodiesterase 5 Inhibitors*/pharmacology , Urinary Bladder*, Animals ; Swine ; Sildenafil Citrate/pharmacology ; Tadalafil/pharmacology ; Cyclic Nucleotide Phosphodiesterases, Type 5 ; Vasodilation ; Norepinephrine/pharmacology ; Nitric Oxide/pharmacology

المؤلفون: Kalyani P; Department of Neurology, University of Pennsylvania, 3400 Spruce St, Philadelphia, PA, 19104, USA. Priyanka.Kalyani@pennmedicine.upenn.edu., Lippa SM; Walter Reed National Military Medical Center, The National Intrepid Center of Excellence, Palmer Rd S, Bethesda, MD, 20814, USA.; Department of Neuroscience, Uniformed Services University Health Sciences, 4301, Jones Bridge Rd, Bethesda, MD, 20814, USA., Werner JK; Walter Reed National Military Medical Center, The National Intrepid Center of Excellence, Palmer Rd S, Bethesda, MD, 20814, USA.; Department of Neuroscience, Uniformed Services University Health Sciences, 4301, Jones Bridge Rd, Bethesda, MD, 20814, USA., Amyot F; Walter Reed National Military Medical Center, The National Intrepid Center of Excellence, Palmer Rd S, Bethesda, MD, 20814, USA., Moore CB; Department of Neuroscience, Uniformed Services University Health Sciences, 4301, Jones Bridge Rd, Bethesda, MD, 20814, USA., Kenney K; Department of Neuroscience, Uniformed Services University Health Sciences, 4301, Jones Bridge Rd, Bethesda, MD, 20814, USA., Diaz-Arrastia R; Department of Neurology, University of Pennsylvania, 3400 Spruce St, Philadelphia, PA, 19104, USA.

المصدر: Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics [Neurotherapeutics] 2023 Oct; Vol. 20 (6), pp. 1629-1640. Date of Electronic Publication: 2023 Sep 11.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Elsevier Inc. on behalf of American Society for Experimental NeuroTherapeutics Country of Publication: United States NLM ID: 101290381 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-7479 (Electronic) Linking ISSN: 18787479 NLM ISO Abbreviation: Neurotherapeutics Subsets: MEDLINE

مواضيع طبية MeSH: Phosphodiesterase 5 Inhibitors*/therapeutic use , Brain Injuries, Traumatic*/complications , Brain Injuries, Traumatic*/drug therapy , Brain Injuries, Traumatic*/pathology, Humans ; Cyclic Nucleotide Phosphodiesterases, Type 5 ; Sildenafil Citrate/therapeutic use ; Cerebrovascular Circulation/physiology ; Biomarkers

المؤلفون: Menger MM; Department of Trauma and Reconstructive Surgery, Eberhard Karls University Tuebingen, BG Trauma Center Tuebingen, 72076, Tuebingen, Germany. mmenger@bgu-tuebingen.de.; Institute for Clinical and Experimental Surgery, Saarland University, 66421, Homburg, Saar, Germany. mmenger@bgu-tuebingen.de., Bauer D; Institute for Clinical and Experimental Surgery, Saarland University, 66421, Homburg, Saar, Germany., Bleimehl M; Institute for Clinical and Experimental Surgery, Saarland University, 66421, Homburg, Saar, Germany., Scheuer C; Institute for Clinical and Experimental Surgery, Saarland University, 66421, Homburg, Saar, Germany., Braun BJ; Department of Trauma and Reconstructive Surgery, Eberhard Karls University Tuebingen, BG Trauma Center Tuebingen, 72076, Tuebingen, Germany., Herath SC; Department of Trauma and Reconstructive Surgery, Eberhard Karls University Tuebingen, BG Trauma Center Tuebingen, 72076, Tuebingen, Germany., Rollmann MF; Department of Trauma and Reconstructive Surgery, Eberhard Karls University Tuebingen, BG Trauma Center Tuebingen, 72076, Tuebingen, Germany., Menger MD; Institute for Clinical and Experimental Surgery, Saarland University, 66421, Homburg, Saar, Germany., Laschke MW; Institute for Clinical and Experimental Surgery, Saarland University, 66421, Homburg, Saar, Germany., Histing T; Department of Trauma and Reconstructive Surgery, Eberhard Karls University Tuebingen, BG Trauma Center Tuebingen, 72076, Tuebingen, Germany.

المصدر: Journal of translational medicine [J Transl Med] 2023 Sep 08; Vol. 21 (1), pp. 607. Date of Electronic Publication: 2023 Sep 08.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 101190741 Publication Model: Electronic Cited Medium: Internet ISSN: 1479-5876 (Electronic) Linking ISSN: 14795876 NLM ISO Abbreviation: J Transl Med Subsets: MEDLINE

مواضيع طبية MeSH: Phosphodiesterase 5 Inhibitors*/pharmacology , Phosphodiesterase 5 Inhibitors*/therapeutic use , Vascular Endothelial Growth Factor A*, Animals ; Mice ; Sildenafil Citrate/pharmacology ; Sildenafil Citrate/therapeutic use ; Cyclic Nucleotide Phosphodiesterases, Type 5 ; X-Ray Microtomography ; Bone Regeneration ; Atrophy

المؤلفون: Varghese R; Poona College of Pharmacy, Bharati Vidyapeeth (Deemed to be) University, Pune, Maharashtra, India.; Department of Clinical Pharmacology, Advanced Centre for Treatment, Research, and Education in Cancer, Tata Memorial Centre, Kharghar, Navi Mumbai, India.; Homi Bhabha National Institute, Mumbai, Maharashtra, India., Digholkar G; Poona College of Pharmacy, Bharati Vidyapeeth (Deemed to be) University, Pune, Maharashtra, India., Karsiya J; River Route Creative Group LLP, Mumbai, Maharashtra, India., Salvi S; Poona College of Pharmacy, Bharati Vidyapeeth (Deemed to be) University, Pune, Maharashtra, India., Shah J; Department of Pulmonology, Saifee Hospital, Girgaon, Mumbai, Maharashtra, India., Kumar D; Poona College of Pharmacy, Bharati Vidyapeeth (Deemed to be) University, Pune, Maharashtra, India.; Department of Entomology, University of California, Davis, CA, USA.; UC Davis Comprehensive Cancer Center, University of California, Davis, CA, USA., Sharma R; Department of Rasa Shastra and Bhaishajya Kalpana, Faculty of Ayurveda, Institute of Medical Sciences, Banaras Hindu University, Varanasi, Uttar Pradesh, India.

المصدر: Drug metabolism and personalized therapy [Drug Metab Pers Ther] 2023 Aug 24; Vol. 38 (4), pp. 295-307. Date of Electronic Publication: 2023 Aug 24 (Print Publication: 2023).

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: De Gruyter Country of Publication: Germany NLM ID: 101653409 Publication Model: eCollection Cited Medium: Internet ISSN: 2363-8915 (Electronic) Linking ISSN: 23638915 NLM ISO Abbreviation: Drug Metab Pers Ther Subsets: MEDLINE

مواضيع طبية MeSH: Phosphodiesterase 5 Inhibitors*/therapeutic use , COVID-19*, Humans ; Sildenafil Citrate ; Tadalafil ; Vardenafil Dihydrochloride ; Cyclic Nucleotide Phosphodiesterases, Type 5 ; Piperazines/pharmacology ; Imidazoles/adverse effects ; Carbolines/adverse effects ; Purines/adverse effects ; SARS-CoV-2