المؤلفون: Manel BenAissa, Gregory R. J. Thatcher, Marton I. Siklos

المصدر: Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica B, Vol 5, Iss 6, Pp 506-519 (2015)

مصطلحات موضوعية: AD, Alzheimer׳s disease, APP/PS1, Aβ overexpressing mice APP (K670N/M671L) and PS1 (M146L) mutants, Review, Cdk5/p35, activator of cyclin-dependent kinase 5, NFT, neurofibrilliary tangles, Cathepsin B, Deubiquitinating enzyme, AppSwe, Swedish amyloid precursor protein mutation, APP (K670N/M671L), Aβ1-42, amyloid β, 42 amino acid protein, AppLon, London familial amyloid precursor protein mutation, APP (V717I), Met, methionine, GSH, glutathione, BACE-1, β-amyloid cleaving enzyme, General Pharmacology, Toxicology and Pharmaceutics, CREB, cyclic adenosine monophosphate response element binding protein, BBB, blood–brain barrier, Hsp70.1, heat shock protein 70.1, PD, Parkinson׳s disease, Caspase, Glu, glutamic acid, TNF, tumor necrosis factor, biology, Alzheimer׳s disease, Chemistry, Calpain, Enzyme inhibitors, ALS, amyotrophic lateral sclerosis, Cysteine protease, isoAsp, isoaspartate, PTP1B, protein-tyrosine phosphatase 1B, Biochemistry, SP, senile plaques, Gln, glutamine, Pro, proline, Val, valine, Phe, phenylalanine, Lys, lysine, Proteases, Aβ, amyloid β, pGlu, pyroglutamate, Thr, threonine, WRX, Trp-Arg containing epoxysuccinate cysteine protease inhibitor, CNS, central nervous system, PK, pharmacokinetic, CaMKII, Ca2+/calmodulin-dependent protein kinases II, TBI, traumatic brain injury, Leu, leucine, Cathepsin, Ala, alanine, MAP-2, microtubule-associated protein 2, APP, amyloid precursor protein, PKC, protein kinase C, WT, wildtype, pyroGluAβ, pyroglutamate-amyloid β, Neurodegeneration, Nle, norleucine, Ile, isoleucine, MMP-9, matrix metalloproteinase 9, Arg, arginine, KO, knockout, CANP, calcium-activated neutral protease, lcsh:RM1-950, Tyr, tyrosine, ERK1/2, extracellular signal-regulated kinase 1/2, EGFR, epidermal growth factor receptor, lcsh:Therapeutics. Pharmacology, biology.protein, DTT, dithioerythritol, Gly, glutamine, Cysteine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84cd76d54a3373da5096eb50f795ee62

المؤلفون: Siklos M; Department of Medicinal Chemistry and Pharmacognosy, University of Illinois College of Pharmacy, Chicago, IL 60612-7231, USA., BenAissa M; Department of Medicinal Chemistry and Pharmacognosy, University of Illinois College of Pharmacy, Chicago, IL 60612-7231, USA., Thatcher GR; Department of Medicinal Chemistry and Pharmacognosy, University of Illinois College of Pharmacy, Chicago, IL 60612-7231, USA.

المصدر: Acta pharmaceutica Sinica. B [Acta Pharm Sin B] 2015 Nov; Vol. 5 (6), pp. 506-19. Date of Electronic Publication: 2015 Sep 26.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101600560 Publication Model: Print-Electronic Cited Medium: Print ISSN: 2211-3835 (Print) Linking ISSN: 22113835 NLM ISO Abbreviation: Acta Pharm Sin B Subsets: PubMed not MEDLINE