المؤلفون: Mahmud, Hussain, Matthew C, Cummins, Stuart, Endo-Streeter, John, Sondek, Brian, Kuhlman

المصدر: The Journal of Biological Chemistry

مصطلحات موضوعية: Models, Molecular, heterotrimeric G protein, Phospholipase C beta, Rosetta molecular modeling program, Protein Engineering, peptide interaction, GAP, GTPase-activating protein, SRE, serum response element, FACS, fluorescent-activated cell sorting, Humans, cancer, PLC-β, phospholipase C-β, Cloning, Molecular, Gαq, phospholipase C, Databases, Protein, protein design, CD, circular dichroism, GPCR, G-protein-coupled receptor, molecular modeling, Editors' Pick, HTH, helix-turn-helix, Recombinant Proteins, HEK293 Cells, Drug Design, GTP-Binding Protein alpha Subunits, Gq-G11, Peptides, Protein Binding, Research Article

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::b312183ea3757d6df7e63b851043a207
https://pubmed.ncbi.nlm.nih.gov/34715131

المؤلفون: András Balla, Gábor Turu, László Hunyady, Péter Várnai, Dániel Garger, Eszter Soltész-Katona, Susanne Prokop, András Tóth

المصدر: The Journal of Biological Chemistry

مصطلحات موضوعية: 0301 basic medicine, Bioluminescence Resonance Energy Transfer Techniques, PIP2, phosphatidylinositol 4,5-bisphosphate, AT1R, AT1 angiotensin receptor, cell surface receptor, NanoLuciferase (NanoLuc), Ligands, Biochemistry, Receptors, G-Protein-Coupled, D1R, D1 dopamine receptor, chemistry.chemical_compound, NanoLuc, NanoLuciferase, SRE, serum response element, GLuc, Gaussia luciferase, Receptor, Luciferases, bioluminescence resonance energy transfer (BRET), biology, Protein Transport, PM, plasma membrane, Biological Assay, Signal transduction, α1AAR, α1A adrenergic receptor, signal transduction, Research Article, Protein Binding, ligand binding, TfR, transferrin receptor, Gaussia luciferase (GLuc), 03 medical and health sciences, Gaussia, TAMRA‒AngII, red fluorophore–conjugated angiotensin II, Coelenterazine, Bioluminescence, Humans, Luciferase, BRET, bioluminescence resonance energy transfer, Molecular Biology, G protein-coupled receptor, 030102 biochemistry & molecular biology, Cell Membrane, molecular pharmacology, G protein–coupled receptor (GPCR), Cell Biology, biology.organism_classification, EGFR, epidermal growth factor receptor, β2AR, β2 adrenergic receptor, Kinetics, 030104 developmental biology, HEK293 Cells, chemistry, Energy Transfer, Biophysics, GPCR, G protein–coupled receptor, DN-Dyn, dominant negative form of dynamin2A, Biosensor

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8666eb7ce2fd2ee3fcd92d011eb7a65b
http://europepmc.org/articles/PMC7950324

المؤلفون: Kendra S. Carmon, Ling Wu, Liezl E. Francisco, Joan Jacob, Tressie A. Posey, Sheng Zhang, Qingyun Liu, Wangsheng Yu, Treena Chatterjee

المصدر: The Journal of Biological Chemistry

مصطلحات موضوعية: 0301 basic medicine, Serum Response Factor, RHOA, ADGRG1, Carcinogenesis, focal adhesion kinase (Fak), Biochemistry, Receptors, G-Protein-Coupled, GPR56, G-protein-coupled receptor 56, RhoA, Ras homolog family member A, siRNA, small interfering ribonucleic acid, SRE, serum response element, Phosphorylation, biology, Chemistry, Antibodies, Monoclonal, Adhesion G-Protein Coupled Receptor G1, G-protein-coupled receptor (GPCR), Cell biology, Gene Expression Regulation, Neoplastic, src-Family Kinases, 7TM, seven-transmembrane, CRC, colorectal cancer, Pax, paxillin, shRNA, short hairpin ribonucleic acid, Colorectal Neoplasms, Signal Transduction, Research Article, Src, CTF, C-terminal fragment, Proto-oncogene tyrosine-protein kinase Src, GPS, GPCR Proteolysis Site, colorectal cancer (CRC), Focal adhesion, 03 medical and health sciences, Cell Line, Tumor, SRF-RE, serum response factor response element, Humans, mAb, monoclonal antibody, Cell adhesion, Molecular Biology, Paxillin, KD, knockdown, paxillin, 030102 biochemistry & molecular biology, STP, Serine–Threonine–Proline-rich, GAIN, GPCR-autoproteolysis inducing, PLL, Pentraxin/Laminin/neurexin/sex-hormone(LNS)-binding-globulin-Like, aGPCR, adhesion G-protein-coupled receptor, cell adhesion, Src, Src proto-oncogene, nonreceptor tyrosine kinase, Cell Biology, ECD, extracellular domain, WT, wild-type, Fak, focal adhesion kinase, NTF, N-terminal fragment, 030104 developmental biology, GPR56, monoclonal antibody, Focal Adhesion Kinase 1, ADGRG1, adhesion G protein-coupled receptor G1, ICC, immunocytochemistry, biology.protein, rhoA GTP-Binding Protein

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0b4abb066910ede52227a334ddae9c2
https://doi.org/10.1016/j.jbc.2021.100261

المؤلفون: Evi Kostenis, Nicole Merten, Max Crüsemann, Julian Patt, Nina Heycke, Uli Rick, Eva Marie Pfeil, Gabriele M. König, Funda Eryilmaz, Stefan Kehraus, Jan H. Voss, Xavier Deupi, Christa E. Müller, Asuka Inoue, Judith Alenfelder

المصدر: The Journal of Biological Chemistry

مصطلحات موضوعية: 0301 basic medicine, loss-of-function mutagenesis, Biochemistry, G protein inhibitor, Adenylyl cyclase, chemistry.chemical_compound, FR900359, label-free biosensor, Arg60, arginine 60, SRE, serum response element, Depsipeptides, Heterotrimeric G protein, HBSS, Hanks' buffered salt solution, RTK, receptor tyrosine kinases, AC, adenylyl cyclase, HTRF, homogeneous time resolved fluorescence, biology, G proteins, guanine nucleotide-binding proteins, DMR, dynamic mass redistribution, Heterotrimeric GTP-Binding Proteins, GTP-Binding Protein alpha Subunits, Cell biology, Gq alpha subunit, PTX, pertussis toxin, FR, FR900359, Signal transduction, Signal Transduction, Research Article, heterotrimeric G protein, CCh, carbachol, G protein, UBO-QIC, YM-254890, YM, YM-254890, Peptides, Cyclic, GEF, guanine nucleotide exchange factor, 03 medical and health sciences, PLC, phospholipase C, PDB, Protein Data Bank, Humans, Gαq, dynamic mass redistribution (DMR), Molecular Biology, G protein-coupled receptor, IP1, inositol monophosphate, 030102 biochemistry & molecular biology, Phospholipase C, HEK 293 cells, Cell Biology, HEK293 Cells, 030104 developmental biology, chemistry, biology.protein, GTP-Binding Protein alpha Subunits, Gq-G11, GPCR, G protein–coupled receptor, FCS, fetal calf serum, HA, hemagglutinin

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dad14382365f90e4057dbc24db130542
https://doi.org/10.1016/j.jbc.2021.100472

المؤلفون: Louise Blair, Igor Stagljar, Julia Petschnigg, Igor Jurisica, Max Kotlyar, Robin Ketteler

المصدر: Journal of Molecular Biology

مصطلحات موضوعية: 0301 basic medicine, PEI, polyethylenimine, TF, transcription factor, Receptor tyrosine kinase, TACC, transforming acidic coiled-coil protein, Small hairpin RNA, ERK, extracellular signal-regulated kinase, Structural Biology, SRE, serum response element, Carcinoma, Non-Small-Cell Lung, ERBB3, Epidermal growth factor receptor, Nub, N-terminal half of ubiquitin, oncogenic signaling, Phosphorylation, RNA, Small Interfering, MOI, multiplicity of infection, GFP, green fluorescent protein, DMEM, Dulbecco's modified Eagle's medium, biology, 3. Good health, ErbB Receptors, Gene Expression Regulation, Neoplastic, two-hybrid screening, GRB2, Mitogen-Activated Protein Kinases, Microtubule-Associated Proteins, Signal Transduction, FGFR, fibroblast growth factor receptor, Cell Survival, EGFR-ex19del, EGFR-exon19 deletion, EGFR, PBS, phosphate-buffered saline, Article, 03 medical and health sciences, TKI, TK inhibitor, SH, Src homology, NSCLC, non-small cell lung cancer, Humans, Immunoprecipitation, Protein Interaction Domains and Motifs, KM, Kaplan–Meier, Protein kinase A, Molecular Biology, PI3K/AKT/mTOR pathway, non-small cell lung cancer, GO, gene ontology, EGF, epidermal growth factor, TK, tyrosine kinase, Computational Biology, EGFR-WT, EGFR-wildtype, Molecular biology, EGFR, epidermal growth factor receptor, Grb2, growth factor receptor-bound protein 2, 030104 developmental biology, HEK293 Cells, protein–protein interaction, MaMTH, mammalian membrane two-hybrid, Cancer research, biology.protein, Cyclin-dependent kinase 8, Cub, C-terminal half of ubiquitin, Gene Deletion, MAPK, mitogen-activated protein kinase, HeLa Cells

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfe1f150f5ffd989d33d7746048b2b75
https://pubmed.ncbi.nlm.nih.gov/27956147

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المصدر: DTIC AND NTIS

مصطلحات الفهرس: Biochemistry, Medicine and Medical Research, Pharmacology, DEOXYRIBONUCLEIC ACIDS, GENES, BREAST CANCER, ACTIVATION, BIOLOGY, INTERACTIONS, POLYMERS, AMINES, MOLECULAR STRUCTURE, CYTOTOXINS, PATHOLOGY, DRUGS, BLOOD SERUM, CELLS(BIOLOGY), ASSAYING, RECEPTOR SITES(PHYSIOLOGY), ANTIBIOTICS, ONCOGENIC VIRUSES, ANTINEOPLASTIC AGENTS., TF(TRANSCRIPTION FACTOR), SRE(SERUM RESPONSE ELEMENT), FMGT(FLUORESCENT MICROGONOTROPENS), ANTICANCER DNA-BINDING DRUGS, ETS TRANSCRIPTION FACTORS, ONCOGENIC GENE EXPRESSION, Text

URL: https://apps.dtic.mil/docs/citations/ADA405260