المؤلفون: Thomas Laeger, Louise Fritsche, Christian Baumeier, Norbert Stefan, Annette Schürmann, Sophie Saussenthaler, Andreas Fritsche, Robert W. Schwenk, Maria Rödiger, Hans-Ulrich Häring, Luisa Schlüter, Stella Amelie Alaze

المصدر: Molecular Metabolism
Mol. Metab. 6, 1254-1263 (2017)
Molecular Metabolism, Vol 6, Iss 10, Pp 1254-1263 (2017)

مصطلحات موضوعية: 0301 basic medicine, Male, HFD, high-fat diet, PPARγ, medicine.medical_treatment, CD36, Adipose tissue, AST, aspartate aminotransferase, SM, skeletal muscle, Mice, F4/80, adhesion G protein-coupled receptor E1, GGT, gamma-glutamyl transpeptidase, Non-alcoholic Fatty Liver Disease, Insulin, rmDPP4, recombinant mouse dipeptidyl peptidase 4, rhDPP4, recombinant human dipeptidyl peptidase 4, Fatty liver, Ad, adenovirus, sWAT, subcutaneous white adipose tissue, Hep G2 Cells, Middle Aged, Dgat2, diacylglycerol O-acyltransferase 2, Cd36, Dpp4, Glp-1, Insulin Resistance, Nafld, Pparγ, TNFα, tumor necrosis factor α, Liver, Cpt1a, carnitine palmitoyltransferase 1a, MOGAT1, monoacylglycerol O-acyltransferase 1, Original Article, Female, medicine.symptom, PPARγ, peroxisome proliferator activated receptor gamma, Dpp4-Liv-Tg, transgenic mice with hepatocyte-specific Dpp4 overexpression, NFκB, nuclear factor-κB, Adult, lcsh:Internal medicine, medicine.medical_specialty, NAFLD, non-alcoholic fatty liver disease, Akt, Akt serine–threonine protein kinase, HOMA-IR, homeostatic model assessment for insulin resistance, IL6, interleukin 6, NASH, non-alcoholic steatohepatitis, Dipeptidyl Peptidase 4, gWAT, gonadal white adipose tissue, Inflammation, Srebf1, sterol regulatory element binding transcription factor 1, Mice, Transgenic, Biology, DPP4, 03 medical and health sciences, Insulin resistance, Internal medicine, NAFLD, ALT, alanine aminotransferase, medicine, Animals, Humans, ApoB, apolipoprotein B, GLP-1, glucagon-like peptide 1, Obesity, lcsh:RC31-1245, Molecular Biology, pAkt, phosphorylated Akt serine–threonine protein kinase, Cell Biology, medicine.disease, CD36, fatty acid translocase, DPP4, dipeptidyl peptidase 4, WT, wild-type, BAT, brown adipose tissue, Insulin receptor, Disease Models, Animal, 030104 developmental biology, Endocrinology, biology.protein, Hepatocytes, Gfp, green fluorescent protein, Steatosis, GLP-1, MCP1, chemokine (C-C motif) ligand 2, MAPK, mitogen-activated protein kinase

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec108ccaaae2e081b54e4ea79fe8b459

المؤلفون: Raphaela, Kübeck, Catalina, Bonet-Ripoll, Christina, Hoffmann, Alesia, Walker, Veronika Maria, Müller, Valentina Luise, Schüppel, Ilias, Lagkouvardos, Birgit, Scholz, Karl-Heinz, Engel, Hannelore, Daniel, Philippe, Schmitt-Kopplin, Dirk, Haller, Thomas, Clavel, Martin, Klingenspor

المصدر: Molecular Metabolism, Vol 5, Iss 12, Pp 1162-1174 (2016)
Mol. Metab. 5, 1162-1174 (2016)
Molecular Metabolism

مصطلحات موضوعية: Male, Diet-induced obesity resistance, Hsp90, heat shock protein 90, CIDEA, cell death inducing DFFA-like effector, COX4, cytochrome c oxidase subunit 4, BMR, basal metabolic rate, Cyp27a1, cholesterol 27 alpha-hydroxylase, Cholesterol, Dietary, Hprt1, hypoxanthine guanine phosphoribosyl transferase, Mice, DEE, daily energy expenditure, GF, germfree, MCA, muricholic acid, qPCR, quantitative real-time polymerase chain reaction, ANOVA, analysis of variance, Eef2, eukaryotic elongation factor 2, CA, cholic acid, PHFD, high-fat diet based on palm oil, Dhcr7, 7-dehydrocholesterol reductase, Hmgcr, 3-hydroxy-3-methylglutaryl Coenzyme A reductase, Cyp7a1, cholesterol 7 alpha-hydroxylase, Abcg8, ATP-binding cassette sub-family G member 8, HP, heat production, Tf2b, transcription factor II B, Cholesterol, High-fat diet, Adipose Tissue, Liver, Abcg5, ATP-binding cassette sub-family G member 5, Original Article, CD, control diet, Akr1d1, aldo-keto-reductase family member 1, PRDM16, PR domain containing 16, LHFD, high-fat diet based on lard, lcsh:Internal medicine, Hsd11b1, hydroxysteroid (11-β) dehydrogenase 1, TCA, taurocholic acid, Srebf1, sterol regulatory element binding transcription factor 1, Energy balance, Ldlr, low density lipoprotein receptor, Diet, High-Fat, digestive system, SPF, specific pathogen free, GUSB, beta-glucuronidase, UDCA, ursodeoxycholic acid, CDCA, chenodeoxycholic acid, Nr1h2, nuclear receptor subfamily 1, group H, member 2 (liver X receptor β), UCP1, uncoupling protein 1, Animals, UPLC-TOF-MS, ultraperformance liquid chromatography-time of flight-mass spectrometry, Obesity, Germfree, FT-IR, Fourier transform-infrared spectroscopy, lcsh:RC31-1245, Nr1h3, nuclear receptor subfamily 1, group H, member 3 (liver X receptor α), TMCA, Tauromuricholic acid, Diet-induced Obesity Resistance, Energy Balance, High-fat Diet, DIO, diet-induced obesity, Lipid Metabolism, Dietary Fats, Gastrointestinal Microbiome, Mice, Inbred C57BL, Hmgcs, 3-hydroxy-3-methylglutaryl Coenzyme A synthase 1, DCA, deoxycholic acid, Actb, beta actin, FT-ICR-MS, Fourier transform-Ion Cyclotron Resonance-Mass Spectrometry, HDCA, hyodeoxycholic acid, Nr1h4, nuclear receptor subfamily 1, group H, member 4 (farnesoid X receptor α)

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::5a00bbb6cef6244342d251ff4ccfc007
http://www.sciencedirect.com/science/article/pii/S2212877816301892

المؤلفون: Takahiro Yamaura, Frank J. Gonzalez, Tadanobu Nagaya, Toshifumi Aoyama, Takefumi Kimura, Naoki Tanaka, Hiroyuki Kitabatake, Kenji Sano, Michiharu Komatsu, Naoyuki Fujimori, Eiji Tanaka, Takeji Umemura, Akira Horiuchi

المصدر: BBA Clinical

مصطلحات موضوعية: Nonalcoholic steatohepatitis, medicine.medical_treatment, BMI, body mass index, FASN, fatty acid synthase, PPAR, peroxisome proliferator-activated receptor, AST, aspartate aminotransferase, Gastroenterology, Nonalcoholic fatty liver disease, TNF, tumor necrosis factor α, CPT1A, carnitine palmitoyl-CoA transferase 1α, NAS, NAFLD activity score, TG, triglyceride, US, ultrasonography, MTTP, microsomal triglyceride transfer protein, SREBF1, sterol regulatory element-binding transcription factor 1, NASH, Regular Article, Hbv hepatitis b virus, FABP, fatty acid-binding protein, γGT, gamma-glutamyltransferase, Pancreaticoduodenectomy, CT, computed tomography, HADHA, hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase α, PPARGC, PPARγ co-activator, Alt alanine aminotransferase, CYBB, cytochrome b-245 β polypeptide, HCV, hepatitis C virus, Molecular Medicine, ACOX1, CYP, cytochrome P450, LPS, lipopolysaccharide, MCD, methionine- and choline-deficient diet, qPCR, quantitative polymerase chain reaction, DGAT, diacylglycerol acyltransferase, NASH, nonalcoholic steatohepatitis, VLDL, TLR, Toll-like receptor, CoA, coenzyme A, medicine.medical_specialty, RXR, retinoid X receptor, NAFLD - Nonalcoholic Fatty Liver Disease, digestive system, Pathology and Forensic Medicine, ROS, reactive oxygen species, SCD, stearoyl-CoA desaturase, PD, pancreaticoduodenectomy, Physiology (medical), Internal medicine, ALT, alanine aminotransferase, SOD, superoxide dismutase, HOMA-IR, homeostasis model assessment for insulin resistance, medicine, ApoB, apolipoprotein B, business.industry, Mechanism (biology), FA, fatty acid, ACACB, acetyl-CoA carboxylase β, nutritional and metabolic diseases, ACACA, acetyl-CoA carboxylase α, VLDL, very-low-density lipoprotein, ACADM, medium-chain acyl-CoA dehydrogenase, TGFB1, transforming growth factor β1, medicine.disease, Fatty acid, MyD88, digestive system diseases, Endocrinology, HBV, hepatitis B virus, ACOX1, acyl-CoA oxidase 1, NAFLD, nonalcoholic fatty liver disease, CAT, catalase, LXR, liver X receptor, business, MYD88, myeloid differentiation primary response 88

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f768717564a8b597fab13ab396fd8aec
https://pubmed.ncbi.nlm.nih.gov/26674248

المؤلفون: Kübeck R; ZIEL - Institute for Food and Health, Technical University of Munich, Gregor-Mendel-Str. 2, 85354 Freising, Germany; Chair of Molecular Nutritional Medicine, Technical University of Munich, TUM School of Life Sciences Weihenstephan, EKFZ - Else Kröner-Fresenius-Center for Nutritional Medicine, Gregor-Mendel-Str. 2, 85354 Freising, Germany., Bonet-Ripoll C; ZIEL - Institute for Food and Health, Technical University of Munich, Gregor-Mendel-Str. 2, 85354 Freising, Germany; Chair of Molecular Nutritional Medicine, Technical University of Munich, TUM School of Life Sciences Weihenstephan, EKFZ - Else Kröner-Fresenius-Center for Nutritional Medicine, Gregor-Mendel-Str. 2, 85354 Freising, Germany., Hoffmann C; ZIEL - Institute for Food and Health, Technical University of Munich, Gregor-Mendel-Str. 2, 85354 Freising, Germany; Chair of Molecular Nutritional Medicine, Technical University of Munich, TUM School of Life Sciences Weihenstephan, EKFZ - Else Kröner-Fresenius-Center for Nutritional Medicine, Gregor-Mendel-Str. 2, 85354 Freising, Germany., Walker A; Research Unit Analytical BioGeoChemistry, Department of Environmental Sciences, Helmholtz Zentrum München, Ingolstädter Landstr.1, 85764 Neuherberg, Germany., Müller VM; ZIEL - Institute for Food and Health, Technical University of Munich, Gregor-Mendel-Str. 2, 85354 Freising, Germany; Chair of Nutritional Physiology, Technical University of Munich, TUM School of Life Sciences Weihenstephan, Gregor-Mendel-Str. 2, 85354 Freising, Germany., Schüppel VL; ZIEL - Institute for Food and Health, Technical University of Munich, Gregor-Mendel-Str. 2, 85354 Freising, Germany; Chair of Nutrition and Immunology, Technical University of Munich, TUM School of Life Sciences Weihenstephan, Maximus-von-Imhof-Forum 2, 85354 Freising, Germany., Lagkouvardos I; ZIEL - Institute for Food and Health, Technical University of Munich, Gregor-Mendel-Str. 2, 85354 Freising, Germany., Scholz B; Chair of General Food Technology, Technische Universität München, Alte Akademie 10, 85354 Freising, Germany., Engel KH; Chair of General Food Technology, Technische Universität München, Alte Akademie 10, 85354 Freising, Germany., Daniel H; Chair of Nutritional Physiology, Technical University of Munich, TUM School of Life Sciences Weihenstephan, Gregor-Mendel-Str. 2, 85354 Freising, Germany., Schmitt-Kopplin P; ZIEL - Institute for Food and Health, Technical University of Munich, Gregor-Mendel-Str. 2, 85354 Freising, Germany; Research Unit Analytical BioGeoChemistry, Department of Environmental Sciences, Helmholtz Zentrum München, Ingolstädter Landstr.1, 85764 Neuherberg, Germany; Chair of Analytical Food Chemistry, Technische Universität München, Alte Akademie 10, 85354 Freising, Germany., Haller D; ZIEL - Institute for Food and Health, Technical University of Munich, Gregor-Mendel-Str. 2, 85354 Freising, Germany; Chair of Nutrition and Immunology, Technical University of Munich, TUM School of Life Sciences Weihenstephan, Maximus-von-Imhof-Forum 2, 85354 Freising, Germany., Clavel T; ZIEL - Institute for Food and Health, Technical University of Munich, Gregor-Mendel-Str. 2, 85354 Freising, Germany., Klingenspor M; ZIEL - Institute for Food and Health, Technical University of Munich, Gregor-Mendel-Str. 2, 85354 Freising, Germany; Chair of Molecular Nutritional Medicine, Technical University of Munich, TUM School of Life Sciences Weihenstephan, EKFZ - Else Kröner-Fresenius-Center for Nutritional Medicine, Gregor-Mendel-Str. 2, 85354 Freising, Germany. Electronic address: mk@tum.de.

المصدر: Molecular metabolism [Mol Metab] 2016 Oct 13; Vol. 5 (12), pp. 1162-1174. Date of Electronic Publication: 2016 Oct 13 (Print Publication: 2016).

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier GmbH Country of Publication: Germany NLM ID: 101605730 Publication Model: eCollection Cited Medium: Internet ISSN: 2212-8778 (Electronic) Linking ISSN: 22128778 NLM ISO Abbreviation: Mol Metab Subsets: MEDLINE

مواضيع طبية MeSH: Dietary Fats/*adverse effects , Gastrointestinal Microbiome/*physiology , Obesity/*metabolism, Adipose Tissue/metabolism ; Animals ; Cholesterol/metabolism ; Cholesterol, Dietary/metabolism ; Diet, High-Fat/adverse effects ; Dietary Fats/metabolism ; Lipid Metabolism/genetics ; Liver/metabolism ; Male ; Mice ; Mice, Inbred C57BL

المؤلفون: Nagaya T; Department of Gastroenterology, Shinshu University School of Medicine, Matsumoto, Japan., Tanaka N; Department of Gastroenterology, Shinshu University School of Medicine, Matsumoto, Japan ; Department of Metabolic Regulation, Shinshu University Graduate School of Medicine, Matsumoto, Japan., Kimura T; Department of Gastroenterology, Shinshu University School of Medicine, Matsumoto, Japan., Kitabatake H; Department of Gastroenterology, Shinshu University School of Medicine, Matsumoto, Japan., Fujimori N; Department of Gastroenterology, Shinshu University School of Medicine, Matsumoto, Japan., Komatsu M; Department of Gastroenterology, Shinshu University School of Medicine, Matsumoto, Japan., Horiuchi A; Digestive Disease Center, Showa Inan General Hospital, Komagane, Japan., Yamaura T; Department of Gastroenterology, Iida Municipal Hospital, Iida, Japan., Umemura T; Department of Gastroenterology, Shinshu University School of Medicine, Matsumoto, Japan., Sano K; Department of Laboratory Medicine, Shinshu University Hospital, Matsumoto, Japan., Gonzalez FJ; Laboratory of Metabolism, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892, United States., Aoyama T; Department of Metabolic Regulation, Shinshu University Graduate School of Medicine, Matsumoto, Japan., Tanaka E; Department of Gastroenterology, Shinshu University School of Medicine, Matsumoto, Japan.

المصدر: BBA clinical [BBA Clin] 2015 Feb 19; Vol. 3, pp. 168-74. Date of Electronic Publication: 2015 Feb 19 (Print Publication: 2015).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101633879 Publication Model: eCollection Cited Medium: Print ISSN: 2214-6474 (Print) Linking ISSN: 22146474 NLM ISO Abbreviation: BBA Clin Subsets: PubMed not MEDLINE