المؤلفون: Cho Y; Brain Science Institute, Korea Institute of Science and Technology (KIST), 5, Hwarang-ro 14-gil, Seongbuk-gu, Seoul, 02792, Republic of Korea.; Functional Thin Film Laboratory, Department of Chemical and Biomolecular Engineering, Korea Advanced Institute of Science and Technology (KAIST), 291 Daehak-ro, Yuseong-gu, Daejeon, 34141, Republic of Korea., Lee H; Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, 34141, Republic of Korea., Jeong W; Functional Thin Film Laboratory, Department of Chemical and Biomolecular Engineering, Korea Advanced Institute of Science and Technology (KAIST), 291 Daehak-ro, Yuseong-gu, Daejeon, 34141, Republic of Korea., Jung KB; Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, 34141, Republic of Korea., Lee SY; Korea Research Institute of Standards and Science (KRISS), Daejeon, 34141, Republic of Korea., Park S; Functional Thin Film Laboratory, Department of Chemical and Biomolecular Engineering, Korea Advanced Institute of Science and Technology (KAIST), 291 Daehak-ro, Yuseong-gu, Daejeon, 34141, Republic of Korea., Yeun J; Functional Thin Film Laboratory, Department of Chemical and Biomolecular Engineering, Korea Advanced Institute of Science and Technology (KAIST), 291 Daehak-ro, Yuseong-gu, Daejeon, 34141, Republic of Korea., Kwon O; Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, 34141, Republic of Korea., Son JG; Korea Research Institute of Standards and Science (KRISS), Daejeon, 34141, Republic of Korea., Lee TG; Korea Research Institute of Standards and Science (KRISS), Daejeon, 34141, Republic of Korea., Son MY; Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, 34141, Republic of Korea.; KRIBB School of Bioscience, Korea University of Science and Technology (UST), Daejeon, 34113, Republic of Korea.; Department of Biological Science, Sungkyunkwan University, Suwon, 16419, Republic of Korea., Im SG; Functional Thin Film Laboratory, Department of Chemical and Biomolecular Engineering, Korea Advanced Institute of Science and Technology (KAIST), 291 Daehak-ro, Yuseong-gu, Daejeon, 34141, Republic of Korea.

المصدر: Advanced materials (Deerfield Beach, Fla.) [Adv Mater] 2024 Sep; Vol. 36 (36), pp. e2403952. Date of Electronic Publication: 2024 Jul 17.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 9885358 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-4095 (Electronic) Linking ISSN: 09359648 NLM ISO Abbreviation: Adv Mater Subsets: MEDLINE

مواضيع طبية MeSH: Cell Culture Techniques*/methods , Polymers*/chemistry , Pluripotent Stem Cells*/cytology , Induced Pluripotent Stem Cells*/cytology , Induced Pluripotent Stem Cells*/metabolism, Humans ; Human Embryonic Stem Cells/cytology ; Human Embryonic Stem Cells/metabolism ; Laminin/chemistry ; Laminin/pharmacology ; Cell Proliferation/drug effects ; Cell Adhesion/drug effects ; Proteoglycans/chemistry ; Proteoglycans/pharmacology ; Cell Line ; Collagen/chemistry ; Cell Differentiation/drug effects ; Drug Combinations

المؤلفون: Foti R; Plastic Surgery, Department of Surgical Sciences, University of Rome 'Tor Vergata', 00133 Rome, Italy., Storti G; Plastic Surgery, Department of Surgical Sciences, University of Rome 'Tor Vergata', 00133 Rome, Italy., Palmesano M; Plastic Surgery, Department of Surgical Sciences, University of Rome 'Tor Vergata', 00133 Rome, Italy., Scioli MG; Anatomy Pathology Institute, Department of Biomedicine and Prevention, University of Rome 'Tor Vergata', 00133 Rome, Italy., Fiorelli E; Anatomy Pathology Institute, Department of Biomedicine and Prevention, University of Rome 'Tor Vergata', 00133 Rome, Italy., Terriaca S; Anatomy Pathology Institute, Department of Biomedicine and Prevention, University of Rome 'Tor Vergata', 00133 Rome, Italy., Cervelli G; Department of Experimental Medicine, University of Rome 'Tor Vergata', 00133 Rome, Italy., Kim BS; Department of Plastic Surgery and Hand Surgery, University Hospital Zurich, 8006 Zurich, Switzerland., Orlandi A; Anatomy Pathology Institute, Department of Biomedicine and Prevention, University of Rome 'Tor Vergata', 00133 Rome, Italy., Cervelli V; Plastic Surgery, Department of Surgical Sciences, University of Rome 'Tor Vergata', 00133 Rome, Italy.

المصدر: International journal of molecular sciences [Int J Mol Sci] 2024 Aug 01; Vol. 25 (15). Date of Electronic Publication: 2024 Aug 01.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

مواضيع طبية MeSH: Cellular Senescence* , Adipose Tissue*/cytology , Cell Differentiation* , Mesenchymal Stem Cells*/cytology , Mesenchymal Stem Cells*/metabolism, Humans ; Animals ; Adipocytes/cytology ; Adipocytes/metabolism ; Stem Cells/cytology ; Stem Cells/metabolism ; Tissue Engineering/methods

المؤلفون: Negueruela J; Signal Transduction and Metabolism Laboratory, Université libre de Bruxelles, Anderlecht, 1070 Brussels-Capital Region, Belgium. Electronic address: javier.negueruela.escudero@ulb.be., Vandenbempt V; Signal Transduction and Metabolism Laboratory, Université libre de Bruxelles, Anderlecht, 1070 Brussels-Capital Region, Belgium., Talamantes S; Signal Transduction and Metabolism Laboratory, Université libre de Bruxelles, Anderlecht, 1070 Brussels-Capital Region, Belgium., Ribeiro-Costa F; Signal Transduction and Metabolism Laboratory, Université libre de Bruxelles, Anderlecht, 1070 Brussels-Capital Region, Belgium., Nunes M; Signal Transduction and Metabolism Laboratory, Université libre de Bruxelles, Anderlecht, 1070 Brussels-Capital Region, Belgium., Dias A; Signal Transduction and Metabolism Laboratory, Université libre de Bruxelles, Anderlecht, 1070 Brussels-Capital Region, Belgium., Bansal M; Signal Transduction and Metabolism Laboratory, Université libre de Bruxelles, Anderlecht, 1070 Brussels-Capital Region, Belgium. Electronic address: mayank.bansal@ulb.be., Gurzov EN; Signal Transduction and Metabolism Laboratory, Université libre de Bruxelles, Anderlecht, 1070 Brussels-Capital Region, Belgium. Electronic address: esteban.gurzov@ulb.be.

المصدر: STAR protocols [STAR Protoc] 2024 Sep 20; Vol. 5 (3), pp. 103297. Date of Electronic Publication: 2024 Sep 06.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101769501 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2666-1667 (Electronic) Linking ISSN: 26661667 NLM ISO Abbreviation: STAR Protoc Subsets: MEDLINE

مواضيع طبية MeSH: Gene Editing*/methods , CRISPR-Cas Systems*/genetics , Pluripotent Stem Cells*/cytology , Pluripotent Stem Cells*/metabolism , Insulin-Secreting Cells*/cytology , Insulin-Secreting Cells*/metabolism , Protein Tyrosine Phosphatases*/genetics , Protein Tyrosine Phosphatases*/metabolism, Humans ; Mice ; Animals ; Cell Differentiation/genetics ; Human Embryonic Stem Cells/cytology ; Human Embryonic Stem Cells/metabolism

المؤلفون: Fasano C; Unit of Medical Genetics and Neurogenetics, Fondazione IRCCS Istituto Neurologico Carlo Besta, 20133 Milan, Italy., Cavaliere A; Unit of Medical Genetics and Neurogenetics, Fondazione IRCCS Istituto Neurologico Carlo Besta, 20133 Milan, Italy., Tiranti V; Unit of Medical Genetics and Neurogenetics, Fondazione IRCCS Istituto Neurologico Carlo Besta, 20133 Milan, Italy. Electronic address: valeria.tiranti@istituto-besta.it., Peron C; Unit of Medical Genetics and Neurogenetics, Fondazione IRCCS Istituto Neurologico Carlo Besta, 20133 Milan, Italy. Electronic address: camille.peron@istituto-besta.it.

المصدر: STAR protocols [STAR Protoc] 2024 Sep 20; Vol. 5 (3), pp. 103127. Date of Electronic Publication: 2024 Jul 15.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101769501 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2666-1667 (Electronic) Linking ISSN: 26661667 NLM ISO Abbreviation: STAR Protoc Subsets: MEDLINE

مواضيع طبية MeSH: Induced Pluripotent Stem Cells*/cytology , Induced Pluripotent Stem Cells*/metabolism , Mitochondria*/metabolism , Neurons*/metabolism , Neurons*/cytology , Cell Differentiation*/physiology , Oxygen Consumption*/physiology , Cell Respiration*/physiology, Humans ; Neural Stem Cells/cytology ; Neural Stem Cells/metabolism ; Cells, Cultured ; Cell Culture Techniques/methods

المؤلفون: Matsui S; Division of Developmental Biology, Center for Stem Cell & Organoid Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, Department of Pediatrics, College of Medicine, University of Cincinnati, Cincinnati, OH 45229, USA., Shiley JR; Division of Developmental Biology, Center for Stem Cell & Organoid Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, Department of Pediatrics, College of Medicine, University of Cincinnati, Cincinnati, OH 45229, USA., Granitto M; Division of Developmental Biology, Center for Stem Cell & Organoid Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, Department of Pediatrics, College of Medicine, University of Cincinnati, Cincinnati, OH 45229, USA., Ludwig K; Division of Developmental Biology, Center for Stem Cell & Organoid Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, Department of Pediatrics, College of Medicine, University of Cincinnati, Cincinnati, OH 45229, USA., Buckley M; Division of Developmental Biology, Center for Stem Cell & Organoid Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, Department of Pediatrics, College of Medicine, University of Cincinnati, Cincinnati, OH 45229, USA., Koigi S; Division of Developmental Biology, Center for Stem Cell & Organoid Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, Department of Pediatrics, College of Medicine, University of Cincinnati, Cincinnati, OH 45229, USA., Mirizio G; Division of Developmental Biology, Center for Stem Cell & Organoid Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, Department of Pediatrics, College of Medicine, University of Cincinnati, Cincinnati, OH 45229, USA., Hu YC; Division of Developmental Biology, Center for Stem Cell & Organoid Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, Department of Pediatrics, College of Medicine, University of Cincinnati, Cincinnati, OH 45229, USA., Mayhew CN; Division of Developmental Biology, Center for Stem Cell & Organoid Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, Department of Pediatrics, College of Medicine, University of Cincinnati, Cincinnati, OH 45229, USA. Electronic address: christopher.mayhew@cchmc.org., Iwafuchi M; Division of Developmental Biology, Center for Stem Cell & Organoid Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, Department of Pediatrics, College of Medicine, University of Cincinnati, Cincinnati, OH 45229, USA. Electronic address: makiko.iwafuchi@cchmc.org.

المصدر: STAR protocols [STAR Protoc] 2024 Sep 20; Vol. 5 (3), pp. 103221. Date of Electronic Publication: 2024 Jul 31.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101769501 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2666-1667 (Electronic) Linking ISSN: 26661667 NLM ISO Abbreviation: STAR Protoc Subsets: MEDLINE

مواضيع طبية MeSH: CRISPR-Cas Systems*/genetics , Induced Pluripotent Stem Cells*/metabolism , Induced Pluripotent Stem Cells*/cytology , RNA, Guide, CRISPR-Cas Systems*/genetics , Gene Silencing*, Humans ; Lentivirus/genetics ; Clustered Regularly Interspaced Short Palindromic Repeats/genetics ; Pluripotent Stem Cells/cytology ; Pluripotent Stem Cells/metabolism ; Doxycycline/pharmacology

المؤلفون: Lu X; Stem Cell & Gene Therapy, Bio-Techne, Minneapolis, MN 55413, USA., Perr E; Stem Cell & Gene Therapy, Bio-Techne, Minneapolis, MN 55413, USA., Naqvi T; Stem Cell & Gene Therapy, Bio-Techne, Minneapolis, MN 55413, USA., Galitz D; Stem Cell & Gene Therapy, Bio-Techne, Minneapolis, MN 55413, USA., Andersen M; Stem Cell & Gene Therapy, Bio-Techne, Minneapolis, MN 55413, USA., Grabowski D; Protein Development, Bio-Techne, Minneapolis, MN 55413, USA., Person A; Protein Development, Bio-Techne, Minneapolis, MN 55413, USA., Kalyuzhny A; Antibody Applications, Bio-Techne, Minneapolis, MN 55413, USA., Flynn KC; Stem Cell & Gene Therapy, Bio-Techne, Minneapolis, MN 55413, USA.; Department of Biochemistry & Molecular Biology, Colorado State University, Fort Collins, CO 80523, USA.

المصدر: Cells [Cells] 2024 Sep 17; Vol. 13 (18). Date of Electronic Publication: 2024 Sep 17.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101600052 Publication Model: Electronic Cited Medium: Internet ISSN: 2073-4409 (Electronic) Linking ISSN: 20734409 NLM ISO Abbreviation: Cells Subsets: MEDLINE

مواضيع طبية MeSH: Vitronectin*/metabolism , Cell Differentiation* , Induced Pluripotent Stem Cells*/cytology , Induced Pluripotent Stem Cells*/metabolism , Recombinant Proteins*/pharmacology, Humans ; Pluripotent Stem Cells/cytology ; Pluripotent Stem Cells/metabolism ; Animals ; Cell Proliferation ; Cellular Reprogramming/genetics ; Workflow ; Mice

المؤلفون: Oh HG; R&D Center, Brexogen Inc., 3F, 9, Beobwon-ro 8-gil, Songpa-gu, Seoul, 05855, Republic of Korea., Jung M; R&D Center, Brexogen Inc., 3F, 9, Beobwon-ro 8-gil, Songpa-gu, Seoul, 05855, Republic of Korea., Jeong SY; R&D Center, Brexogen Inc., 3F, 9, Beobwon-ro 8-gil, Songpa-gu, Seoul, 05855, Republic of Korea., Kim J; R&D Center, Brexogen Inc., 3F, 9, Beobwon-ro 8-gil, Songpa-gu, Seoul, 05855, Republic of Korea., Han SD; R&D Center, Brexogen Inc., 3F, 9, Beobwon-ro 8-gil, Songpa-gu, Seoul, 05855, Republic of Korea., Kim H; Institute of Green Bio Science and Technology, Seoul National University, 1447 Pyeongchang Daero, Pyeongchang, Gangwon-do, 25354, Republic of Korea., Lee S; R&D Center, Brexogen Inc., 3F, 9, Beobwon-ro 8-gil, Songpa-gu, Seoul, 05855, Republic of Korea., Lee Y; R&D Center, Brexogen Inc., 3F, 9, Beobwon-ro 8-gil, Songpa-gu, Seoul, 05855, Republic of Korea., You H; R&D Center, Brexogen Inc., 3F, 9, Beobwon-ro 8-gil, Songpa-gu, Seoul, 05855, Republic of Korea., Park S; R&D Center, Brexogen Inc., 3F, 9, Beobwon-ro 8-gil, Songpa-gu, Seoul, 05855, Republic of Korea., Kim EA; R&D Center, Brexogen Inc., 3F, 9, Beobwon-ro 8-gil, Songpa-gu, Seoul, 05855, Republic of Korea., Kim TM; Institute of Green Bio Science and Technology, Seoul National University, 1447 Pyeongchang Daero, Pyeongchang, Gangwon-do, 25354, Republic of Korea. taemin21@snu.ac.kr.; Graduate School of International Agricultural Technology, Seoul National University, Pyeongchang, Gangwon-do, 25354, Republic of Korea. taemin21@snu.ac.kr., Kim S; R&D Center, Brexogen Inc., 3F, 9, Beobwon-ro 8-gil, Songpa-gu, Seoul, 05855, Republic of Korea. sue.kim@brexogen.com.

المصدر: Stem cell research & therapy [Stem Cell Res Ther] 2024 Sep 11; Vol. 15 (1), pp. 287. Date of Electronic Publication: 2024 Sep 11.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 101527581 Publication Model: Electronic Cited Medium: Internet ISSN: 1757-6512 (Electronic) Linking ISSN: 17576512 NLM ISO Abbreviation: Stem Cell Res Ther Subsets: MEDLINE

مواضيع طبية MeSH: Extracellular Vesicles*/metabolism , Alopecia*/therapy , Alopecia*/metabolism , Alopecia*/drug therapy , Hyaluronic Acid*/pharmacology , Hyaluronic Acid*/metabolism , Mesenchymal Stem Cells*/metabolism , Mesenchymal Stem Cells*/cytology , Mesenchymal Stem Cells*/drug effects , Hair Follicle*/metabolism , Hair Follicle*/drug effects, Animals ; Mice ; Humans ; Wnt Signaling Pathway/drug effects ; Male ; Receptors, Androgen/metabolism ; Receptors, Androgen/genetics ; Induced Pluripotent Stem Cells/metabolism ; Induced Pluripotent Stem Cells/cytology ; Testosterone/pharmacology ; Glycogen Synthase Kinase 3 beta/metabolism ; Mice, Inbred C57BL

المؤلفون: Oikonomakos I; Université Côte d'Azur, Inserm, CNRS, Institut de Biologie Valrose, 06108 Nice, France; Department of Internal Medicine III, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany., Tedesco M; Université Côte d'Azur, Inserm, CNRS, Institut de Biologie Valrose, 06108 Nice, France., Motamedi FJ; Université Côte d'Azur, Inserm, CNRS, Institut de Biologie Valrose, 06108 Nice, France., Peitzsch M; Institute of Clinical Chemistry and Laboratory Medicine, University Hospital Carl Gustav Carus, Medical Faculty Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany., Nef S; Department of Genetic Medicine and Development, University of Geneva, 1211 Geneva, Switzerland., Bornstein SR; Department of Internal Medicine III, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany., Schedl A; Université Côte d'Azur, Inserm, CNRS, Institut de Biologie Valrose, 06108 Nice, France. Electronic address: schedl@unice.fr., Steenblock C; Department of Internal Medicine III, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany. Electronic address: charlotte.steenblock@ukdd.de., Neirijnck Y; Université Côte d'Azur, Inserm, CNRS, Institut de Biologie Valrose, 06108 Nice, France.

المصدر: Stem cell reports [Stem Cell Reports] 2024 Sep 10; Vol. 19 (9), pp. 1289-1303. Date of Electronic Publication: 2024 Aug 22.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101611300 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2213-6711 (Electronic) Linking ISSN: 22136711 NLM ISO Abbreviation: Stem Cell Reports Subsets: MEDLINE

مواضيع طبية MeSH: Cell Differentiation* , Pluripotent Stem Cells*/metabolism , Pluripotent Stem Cells*/cytology, Animals ; Mice ; Adrenal Cortex/cytology ; Adrenal Cortex/metabolism ; Adrenocorticotropic Hormone/metabolism ; Adrenocorticotropic Hormone/pharmacology ; Steroidogenic Factor 1/metabolism ; Steroidogenic Factor 1/genetics ; Adrenal Cortex Hormones/metabolism ; Mouse Embryonic Stem Cells/metabolism ; Mouse Embryonic Stem Cells/cytology ; Angiotensin II/pharmacology ; Cells, Cultured ; Cyclic AMP-Dependent Protein Kinases/metabolism ; Fibronectins/metabolism

المؤلفون: van der Weijden VA; Department of Genome Regulation, Max Planck Institute for Molecular Genetics, Berlin, Germany., Bulut-Karslioğlu A; Department of Genome Regulation, Max Planck Institute for Molecular Genetics, Berlin, Germany. Electronic address: aydan.karslioglu@molgen.mpg.de.

المصدر: Trends in cell biology [Trends Cell Biol] 2024 Sep; Vol. 34 (9), pp. 700-702. Date of Electronic Publication: 2024 Jun 18.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Science Publishers Country of Publication: England NLM ID: 9200566 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-3088 (Electronic) Linking ISSN: 09628924 NLM ISO Abbreviation: Trends Cell Biol Subsets: MEDLINE

مواضيع طبية MeSH: Embryonic Stem Cells*/metabolism , Embryonic Stem Cells*/cytology, Animals ; Humans ; Adult Stem Cells/metabolism ; Adult Stem Cells/cytology

المؤلفون: Kurashima K; Laboratory of Stem Cell Biology, National Institute for Basic Biology, National Institutes of Natural Sciences, Okazaki, Japan.; Department of Basic Biology, SOKENDAI (The Graduate University for Advanced Studies), Okazaki, Japan., Kamikawa Y; Laboratory of Stem Cell Biology, National Institute for Basic Biology, National Institutes of Natural Sciences, Okazaki, Japan.; Department of Biochemistry, Institute of Biomedical & Health Sciences, Hiroshima University, Hiroshima, Japan., Tsubouchi T; Laboratory of Stem Cell Biology, National Institute for Basic Biology, National Institutes of Natural Sciences, Okazaki, Japan. ttsubo@nibb.ac.jp.; Department of Basic Biology, SOKENDAI (The Graduate University for Advanced Studies), Okazaki, Japan. ttsubo@nibb.ac.jp.

المصدر: EMBO reports [EMBO Rep] 2024 Sep; Vol. 25 (9), pp. 3757-3776. Date of Electronic Publication: 2024 Jul 25.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Wiley Blackwell Country of Publication: England NLM ID: 100963049 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1469-3178 (Electronic) Linking ISSN: 1469221X NLM ISO Abbreviation: EMBO Rep Subsets: MEDLINE

مواضيع طبية MeSH: DNA Replication* , Replication Origin* , Embryonic Stem Cells*/metabolism , Embryonic Stem Cells*/cytology , Cell Cycle*/genetics, Animals ; Mice ; S Phase/genetics ; Ataxia Telangiectasia Mutated Proteins/metabolism ; Ataxia Telangiectasia Mutated Proteins/genetics ; Genomic Instability ; Pluripotent Stem Cells/metabolism ; Pluripotent Stem Cells/cytology ; Humans