المؤلفون: Sasmita, AO, Depp, C, Nazarenko, T, Sun, T, Siems, SB, Ong, EC, Nkeh, YB, Bohler, C, Yu, X, Bues, B, Evangelista, L, Mao, SY, Morgado, B, Wu, Z, Ruhwedel, T, Subramanian, S, Borensen, F, Overhoff, K, Spieth, L, Berghoff, SA, Sadleir, KR, Vassar, R, Eggert, S, Goebbels, S, Saito, T, Saido, T, Saher, G, Mobius, W, Castelo-Branco, G, Klafki, HW, Wirths, O, Wiltfang, J, Jakel, S, Yan, RQ, Nave, KA

المصدر: Nature neuroscience. 27(9):1668-1674

مصطلحات موضوعية: Medicin och hälsovetenskap

URL الوصول: http://kipublications.ki.se/Default.aspx?queryparsed=id:159223978

المؤلفون: Paudel B; Department of Medicine/Division Hematology/Oncology, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA., Jeong SY; Department of Medicine/Division Hematology/Oncology, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA.; Ministry of Food and Drug Safety, Pharmaceutical Safety Bureau, Pharmaceutical Policy Division 187, Osongsaengmyeong 2-ro, Osong-eup, Heungdeok-gu, Cheongju-si, Chungcheongbuk-do, Republic of Korea., Martinez CP; USF Health Byrd Alzheimer's Center and Neuroscience Institute; Department of Molecular Medicine, Morsani College of Medicine, Tampa, FL, 33613, USA., Rickman A; USF Health Byrd Alzheimer's Center and Neuroscience Institute; Department of Molecular Medicine, Morsani College of Medicine, Tampa, FL, 33613, USA., Haluck-Kangas A; Department of Medicine/Division Hematology/Oncology, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA., Bartom ET; Department of Biochemistry and Molecular Genetics, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA.; Department of Preventive Medicine/Division of Biostatistics, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA., Fredriksen K; Davee Department of Neurology, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA., Affaneh A; Davee Department of Neurology, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA., Kessler JA; Davee Department of Neurology, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA., Mazzulli JR; Davee Department of Neurology, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA., Murmann AE; Department of Medicine/Division Hematology/Oncology, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA., Rogalski E; Mesulam Center for Cognitive Neurology and Alzheimer's Disease, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA.; Department of Psychiatry and Behavioral Sciences, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA.; Healthy Aging & Alzheimer's Research Care (HAARC) Center, Department of Neurology, The University of Chicago, Chicago, IL, 60637, USA., Geula C; Mesulam Center for Cognitive Neurology and Alzheimer's Disease, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA.; Department of Psychiatry and Behavioral Sciences, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA., Ferreira A; Department of Cell and Developmental Biology, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA., Heckmann BL; USF Health Byrd Alzheimer's Center and Neuroscience Institute; Department of Molecular Medicine, Morsani College of Medicine, Tampa, FL, 33613, USA., Green DR; Department of Immunology, St. Jude Children's Research Hospital, Memphis, TN, 38105, USA., Sadleir KR; Davee Department of Neurology, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA., Vassar R; Davee Department of Neurology, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA.; Mesulam Center for Cognitive Neurology and Alzheimer's Disease, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA., Peter ME; Department of Medicine/Division Hematology/Oncology, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA. m-peter@northwestern.edu.; Department of Biochemistry and Molecular Genetics, Feinberg School of Medicine, Northwestern University, Chicago, IL, 60611, USA. m-peter@northwestern.edu.

المصدر: Nature communications [Nat Commun] 2024 Jan 18; Vol. 15 (1), pp. 264. Date of Electronic Publication: 2024 Jan 18.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Alzheimer Disease*/genetics , MicroRNAs*/genetics, Mice ; Animals ; Humans ; Aged, 80 and over ; RNA-Induced Silencing Complex/genetics ; RNA Interference ; Aging/genetics ; Amyloid beta-Peptides/genetics ; Amyloid beta-Peptides/toxicity

المؤلفون: Sadleir KR; Davee Department of Neurology and., Vassar R; Davee Department of Neurology and.; Mesulam Center for Cognitive Neurology and Alzheimer's Disease, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.

المصدر: The Journal of clinical investigation [J Clin Invest] 2023 Jul 17; Vol. 133 (14). Date of Electronic Publication: 2023 Jul 17.

نوع المنشور: Journal Article; Comment

بيانات الدورية: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model: Electronic Cited Medium: Internet ISSN: 1558-8238 (Electronic) Linking ISSN: 00219738 NLM ISO Abbreviation: J Clin Invest Subsets: MEDLINE

مواضيع طبية MeSH: Alzheimer Disease*/pathology, Animals ; Humans ; Mice ; Amyloid beta-Peptides/genetics ; Apolipoprotein E4/genetics ; Apolipoproteins E ; Mice, Transgenic ; Sleep Deprivation/genetics ; Sleep Deprivation/complications

المؤلفون: Alia AO; The Ken and Ruth Davee Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL, 60611, USA., Jeon S; The Ken and Ruth Davee Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL, 60611, USA., Popovic J; The Ken and Ruth Davee Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL, 60611, USA., Salvo MA; The Ken and Ruth Davee Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL, 60611, USA., Sadleir KR; The Ken and Ruth Davee Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL, 60611, USA., Vassar R; The Ken and Ruth Davee Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL, 60611, USA.; Mesulam Center for Cognitive Neurology and Alzheimer's Disease, Northwestern University Feinberg School of Medicine, Chicago, IL, 60611, USA., Cuddy LK; The Ken and Ruth Davee Department of Neurology, Northwestern University Feinberg School of Medicine, Chicago, IL, 60611, USA. leah.cuddy@northwestern.edu.

المصدر: Scientific reports [Sci Rep] 2022 Dec 21; Vol. 12 (1), pp. 22099. Date of Electronic Publication: 2022 Dec 21.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

مواضيع طبية MeSH: Integrases*/metabolism , Neuroinflammatory Diseases*/genetics , Neuroinflammatory Diseases*/metabolism , Neuroinflammatory Diseases*/pathology , Genetic Engineering*/methods , Disease Models, Animal*, Animals ; Mice ; Calcium-Calmodulin-Dependent Protein Kinase Type 2/genetics ; Calcium-Calmodulin-Dependent Protein Kinase Type 2/metabolism ; Mice, Transgenic/genetics ; Nestin/genetics ; Nestin/metabolism ; Neuroglia/metabolism ; Synapses/metabolism

المؤلفون: Demonbreun AR; Center for Genetic Medicine.; Department of Pharmacology, and., Bogdanovic E; Center for Genetic Medicine.; Division of Cardiology, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA., Vaught LA; Center for Genetic Medicine.; Division of Cardiology, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA., Reiser NL; Center for Genetic Medicine.; Division of Cardiology, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA., Fallon KS; Center for Genetic Medicine.; Division of Cardiology, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA., Long AM; Center for Genetic Medicine.; Division of Cardiology, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA., Oosterbaan CC; Center for Genetic Medicine.; Division of Cardiology, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA., Hadhazy M; Center for Genetic Medicine.; Division of Cardiology, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA., Page PG; Center for Genetic Medicine., Joseph PRB; WuXi Biology, WuXi AppTec, Cranbury, New Jersey, USA., Cowen G; Center for Genetic Medicine.; Division of Cardiology, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA., Telenson AM; Center for Genetic Medicine., Khatri A; Department of Neurology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA., Sadleir KR; Department of Neurology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA., Vassar R; Department of Neurology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA., McNally EM; Center for Genetic Medicine.; Division of Cardiology, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.

المصدر: JCI insight [JCI Insight] 2022 Jul 22; Vol. 7 (14). Date of Electronic Publication: 2022 Jul 22.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 101676073 Publication Model: Electronic Cited Medium: Internet ISSN: 2379-3708 (Electronic) Linking ISSN: 23793708 NLM ISO Abbreviation: JCI Insight Subsets: MEDLINE

مواضيع طبية MeSH: Annexin A6*/genetics , Annexin A6*/metabolism , Calcium*/metabolism, Animals ; Annexins ; Mice ; Muscle, Skeletal/metabolism ; Myocytes, Cardiac/metabolism

المؤلفون: Sadleir KR; Department of Neurology, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States of America., Popovic J; Department of Neurology, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States of America., Khatri A; Department of Neurology, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States of America., Vassar R; Department of Neurology, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States of America.

المصدر: PloS one [PLoS One] 2022 Feb 02; Vol. 17 (2), pp. e0263332. Date of Electronic Publication: 2022 Feb 02 (Print Publication: 2022).

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

مواضيع طبية MeSH: Disease Models, Animal*, Alzheimer Disease/*drug therapy , Neurites/*drug effects , Neuroaxonal Dystrophies/*drug therapy , Nimodipine/*administration & dosage , Plaque, Amyloid/*drug therapy, Administration, Oral ; Alzheimer Disease/pathology ; Animals ; Calcium Channel Blockers/administration & dosage ; Female ; Humans ; Male ; Mice ; Mice, Transgenic ; Neurites/pathology ; Neuroaxonal Dystrophies/pathology ; Plaque, Amyloid/pathology

المؤلفون: Sadleir KR; Department of Neurology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, United States., Popovoic J; Department of Neurology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, United States., Zhu W; Department of Chemistry, Chemistry of Life Processes Institute, Center for Molecular Innovation and Drug Discovery, Center for Developmental Therapeutics, Northwestern University, Evanston, IL 60611, United States., Reidel CT; Department of Chemistry, Chemistry of Life Processes Institute, Center for Molecular Innovation and Drug Discovery, Center for Developmental Therapeutics, Northwestern University, Evanston, IL 60611, United States., Do H; Department of Chemistry, Chemistry of Life Processes Institute, Center for Molecular Innovation and Drug Discovery, Center for Developmental Therapeutics, Northwestern University, Evanston, IL 60611, United States., Silverman RB; Department of Chemistry, Chemistry of Life Processes Institute, Center for Molecular Innovation and Drug Discovery, Center for Developmental Therapeutics, Northwestern University, Evanston, IL 60611, United States., Vassar R; Department of Neurology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, United States.

المصدر: Current Alzheimer research [Curr Alzheimer Res] 2021; Vol. 18 (4), pp. 283-297.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Bentham Science Publishers Country of Publication: United Arab Emirates NLM ID: 101208441 Publication Model: Print Cited Medium: Internet ISSN: 1875-5828 (Electronic) Linking ISSN: 15672050 NLM ISO Abbreviation: Curr Alzheimer Res Subsets: MEDLINE

مواضيع طبية MeSH: Alzheimer Disease*/drug therapy , Alzheimer Disease*/pathology, Amyloid Precursor Protein Secretases/*metabolism , Plaque, Amyloid/*pathology , Pregabalin/*therapeutic use, Animals ; Disease Models, Animal ; Hippocampus/metabolism ; Humans ; Mice ; Mice, Transgenic ; Neurites/pathology

المؤلفون: Hur JY; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Frost GR; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Program of Neurosciences, Weill Graduate School of Medical Sciences of Cornell University, New York, NY, USA., Wu X; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Crump C; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Program of Pharmacology, Weill Graduate School of Medical Sciences of Cornell University, New York, NY, USA., Pan SJ; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Wong E; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Barros M; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Li T; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Program of Neurosciences, Weill Graduate School of Medical Sciences of Cornell University, New York, NY, USA., Nie P; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.; Program of Pharmacology, Weill Graduate School of Medical Sciences of Cornell University, New York, NY, USA., Zhai Y; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Wang JC; Ronald M. Loeb Center for Alzheimer's Disease, Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Tcw J; Ronald M. Loeb Center for Alzheimer's Disease, Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Guo L; Department of Genetics and Genomic Sciences, Mount Sinai Center for Transformative Disease Modeling, Icahn School of Medicine at Mount Sinai, New York, NY, USA., McKenzie A; Department of Genetics and Genomic Sciences, Mount Sinai Center for Transformative Disease Modeling, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Ming C; Department of Genetics and Genomic Sciences, Mount Sinai Center for Transformative Disease Modeling, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Zhou X; Department of Genetics and Genomic Sciences, Mount Sinai Center for Transformative Disease Modeling, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Wang M; Department of Genetics and Genomic Sciences, Mount Sinai Center for Transformative Disease Modeling, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Sagi Y; Laboratory of Molecular and Cellular Neuroscience, Rockefeller University, New York, NY, USA., Renton AE; Ronald M. Loeb Center for Alzheimer's Disease, Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Esposito BT; Ronald M. Loeb Center for Alzheimer's Disease, Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Kim Y; Laboratory of Molecular and Cellular Neuroscience, Rockefeller University, New York, NY, USA., Sadleir KR; Feinberg School of Medicine, Northwestern University, Chicago, IL, USA., Trinh I; Department of Neurosciences, University of California San Diego, La Jolla, CA, USA., Rissman RA; Department of Neurosciences, University of California San Diego, La Jolla, CA, USA., Vassar R; Feinberg School of Medicine, Northwestern University, Chicago, IL, USA., Zhang B; Department of Genetics and Genomic Sciences, Mount Sinai Center for Transformative Disease Modeling, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Johnson DS; Pfizer Worldwide Research and Development, Cambridge, MA, USA., Masliah E; Department of Neurosciences, University of California San Diego, La Jolla, CA, USA., Greengard P; Laboratory of Molecular and Cellular Neuroscience, Rockefeller University, New York, NY, USA., Goate A; Ronald M. Loeb Center for Alzheimer's Disease, Department of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Department of Genetics and Genomic Sciences, Mount Sinai Center for Transformative Disease Modeling, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Li YM; Chemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA. liy2@mskcc.org.; Program of Neurosciences, Weill Graduate School of Medical Sciences of Cornell University, New York, NY, USA. liy2@mskcc.org.; Program of Pharmacology, Weill Graduate School of Medical Sciences of Cornell University, New York, NY, USA. liy2@mskcc.org.

المصدر: Nature [Nature] 2020 Oct; Vol. 586 (7831), pp. 735-740. Date of Electronic Publication: 2020 Sep 02.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE

مواضيع طبية MeSH: Immunity, Innate*, Alzheimer Disease/*immunology , Alzheimer Disease/*metabolism , Amyloid Precursor Protein Secretases/*metabolism , Membrane Proteins/*metabolism , RNA-Binding Proteins/*metabolism, Age of Onset ; Aged, 80 and over ; Aging/genetics ; Aging/immunology ; Aging/metabolism ; Alzheimer Disease/genetics ; Alzheimer Disease/pathology ; Amyloid Precursor Protein Secretases/chemistry ; Amyloid beta-Protein Precursor/chemistry ; Amyloid beta-Protein Precursor/metabolism ; Animals ; Astrocytes/metabolism ; Catalytic Domain ; Disease Models, Animal ; Female ; HEK293 Cells ; Humans ; Inflammation ; Male ; Membrane Proteins/deficiency ; Membrane Proteins/genetics ; Mice ; Mice, Inbred C57BL ; Mice, Transgenic ; Presenilin-1/metabolism ; RNA-Binding Proteins/genetics ; Risk ; Up-Regulation

المؤلفون: Sadleir KR; Department of Neurology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois. Electronic address: krdoherty@northwestern.edu., Vassar R; Department of Neurology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.

المصدر: Biological psychiatry [Biol Psychiatry] 2019 Aug 01; Vol. 86 (3), pp. 164-166.

نوع المنشور: Journal Article; Comment

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 0213264 Publication Model: Print Cited Medium: Internet ISSN: 1873-2402 (Electronic) Linking ISSN: 00063223 NLM ISO Abbreviation: Biol Psychiatry Subsets: MEDLINE

مواضيع طبية MeSH: Alzheimer Disease* , Cognitive Dysfunction*, Cognition ; Humans ; Post-Synaptic Density ; Ubiquitin

المؤلفون: Sadleir KR; Dept. of Neurology, Feinberg School of Medicine, Northwestern University, Chicago, USA. krdoherty@northwestern.edu., Vassar R; Dept. of Neurology, Feinberg School of Medicine, Northwestern University, Chicago, USA.

المصدر: Lab animal [Lab Anim (NY)] 2019 Mar; Vol. 48 (3), pp. 87-88.

نوع المنشور: Journal Article; Comment

بيانات الدورية: Publisher: Nature America Country of Publication: United States NLM ID: 0417737 Publication Model: Print Cited Medium: Internet ISSN: 1548-4475 (Electronic) Linking ISSN: 00937355 NLM ISO Abbreviation: Lab Anim (NY) Subsets: MEDLINE

مواضيع طبية MeSH: Alzheimer Disease/*genetics, Genetic Variation ; Humans