المؤلفون: Wertman RS; Department of Pathobiology, University of Pennsylvania School of Veterinary Medicine, Philadelphia, PA 19104, USA., Yost W; Department of Pathobiology, University of Pennsylvania School of Veterinary Medicine, Philadelphia, PA 19104, USA., Herrmann BI; Department of Pathobiology, University of Pennsylvania School of Veterinary Medicine, Philadelphia, PA 19104, USA., Bourne CM; Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Sorobetea D; Department of Pathobiology, University of Pennsylvania School of Veterinary Medicine, Philadelphia, PA 19104, USA., Go CK; Department of Pathobiology, University of Pennsylvania School of Veterinary Medicine, Philadelphia, PA 19104, USA., Saller BS; Institute of Neuropathology, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg 79106, Germany.; Faculty of Biology, University of Freiburg, Freiburg 79106, Germany., Groß O; Institute of Neuropathology, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg 79106, Germany.; Signalling Research Centres BIOSS and CIBSS, University of Freiburg, Freiburg 79106, Germany., Scott P; Department of Pathobiology, University of Pennsylvania School of Veterinary Medicine, Philadelphia, PA 19104, USA., Rongvaux A; Translational Science and Therapeutics Division, Fred Hutchinson Cancer Center, Seattle, WA 98109, USA.; Department of Immunology, University of Washington, Seattle, WA 98195, USA., Taabazuing CY; Department of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA., Brodsky IE; Department of Pathobiology, University of Pennsylvania School of Veterinary Medicine, Philadelphia, PA 19104, USA.

المصدر: Science advances [Sci Adv] 2024 Jul 26; Vol. 10 (30), pp. eadl3629. Date of Electronic Publication: 2024 Jul 26.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101653440 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2375-2548 (Electronic) Linking ISSN: 23752548 NLM ISO Abbreviation: Sci Adv Subsets: MEDLINE

مواضيع طبية MeSH: Pyroptosis* , Interleukin-1beta*/metabolism , Caspase 8*/metabolism , Signal Transduction* , Caspase 1*/metabolism , Inflammasomes*/metabolism , Yersinia*/metabolism , Phosphate-Binding Proteins*/metabolism, Animals ; Mice ; Humans ; Bacterial Proteins/metabolism ; Intracellular Signaling Peptides and Proteins/metabolism ; Yersinia Infections/immunology ; Yersinia Infections/microbiology ; Yersinia Infections/metabolism ; Gasdermins

المؤلفون: Wertman RS; Department of Pathobiology, University of Pennsylvania School of Veterinary Medicine, Philadelphia, Pennsylvania, USA 19104., Go CK; Department of Pathobiology, University of Pennsylvania School of Veterinary Medicine, Philadelphia, Pennsylvania, USA 19104., Saller BS; Institute of Neuropathology, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany 79106.; Faculty of Biology, University of Freiburg, Freiburg, Germany 79106., Groß O; Institute of Neuropathology, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany 79106.; Signalling Research Centres BIOSS and CIBSS, University of Freiburg, Freiburg, Germany 79106., Scott P; Department of Pathobiology, University of Pennsylvania School of Veterinary Medicine, Philadelphia, Pennsylvania, USA 19104., Brodsky IE; Department of Pathobiology, University of Pennsylvania School of Veterinary Medicine, Philadelphia, Pennsylvania, USA 19104.

المصدر: BioRxiv : the preprint server for biology [bioRxiv] 2023 Sep 15. Date of Electronic Publication: 2023 Sep 15.

نوع المنشور: Preprint

بيانات الدورية: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

المؤلفون: Neuwirt E; Institute of Neuropathology, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany.; Signalling Research Centres BIOSS and CIBSS, University of Freiburg, 79104 Freiburg, Germany.; Faculty of Biology, University of Freiburg, 79104 Freiburg, Germany., Magnani G; Institute of Clinical Chemistry and Pathobiochemistry, Klinikum rechts der Isar, Technical University of Munich, 81675 Munich, Germany., Ćiković T; Institute of Clinical Chemistry and Pathobiochemistry, Klinikum rechts der Isar, Technical University of Munich, 81675 Munich, Germany.; Center for Translational Cancer Research (TranslaTUM), Technical University of Munich, 81675 Munich, Germany., Wöhrle S; Institute of Neuropathology, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany.; Faculty of Biology, University of Freiburg, 79104 Freiburg, Germany., Fischer L; Institute of Neuropathology, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany.; Faculty of Biology, University of Freiburg, 79104 Freiburg, Germany., Kostina A; Institute of Neuropathology, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany., Flemming S; Bioinformatics Group, Faculty of Engineering, University of Freiburg, 79110 Freiburg, Germany., Fischenich NJ; Institute of Neuropathology, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany., Saller BS; Institute of Neuropathology, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany.; Faculty of Biology, University of Freiburg, 79104 Freiburg, Germany., Gorka O; Institute of Neuropathology, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany., Renner S; Novartis Institutes for BioMedical Research, 4056 Basel, Switzerland., Agarinis C; Novartis Institutes for BioMedical Research, 4056 Basel, Switzerland., Parker CN; Novartis Institutes for BioMedical Research, 4056 Basel, Switzerland., Boettcher A; Novartis Institutes for BioMedical Research, 4056 Basel, Switzerland., Farady CJ; Novartis Institutes for BioMedical Research, 4056 Basel, Switzerland., Kesselring R; Department for General and Visceral Surgery, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany.; German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ) 69120 Heidelberg, Germany., Berlin C; Department for General and Visceral Surgery, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany.; German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ) 69120 Heidelberg, Germany., Backofen R; Signalling Research Centres BIOSS and CIBSS, University of Freiburg, 79104 Freiburg, Germany.; Bioinformatics Group, Faculty of Engineering, University of Freiburg, 79110 Freiburg, Germany., Rodriguez-Franco M; Faculty of Biology, Cell Biology, University of Freiburg, 79104 Freiburg, Germany., Kreutz C; Signalling Research Centres BIOSS and CIBSS, University of Freiburg, 79104 Freiburg, Germany.; Institute of Medical Biometry and Statistics (IMBI), Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany., Prinz M; Institute of Neuropathology, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany.; Signalling Research Centres BIOSS and CIBSS, University of Freiburg, 79104 Freiburg, Germany.; Center for Basics in NeuroModulation (NeuroModulBasics), Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany., Tholen M; Institute for Molecular Medicine and Cell Research, Faculty of Medicine, University of Freiburg, 79104 Freiburg, Germany., Reinheckel T; Signalling Research Centres BIOSS and CIBSS, University of Freiburg, 79104 Freiburg, Germany.; German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ) 69120 Heidelberg, Germany.; Institute for Molecular Medicine and Cell Research, Faculty of Medicine, University of Freiburg, 79104 Freiburg, Germany., Ott T; Signalling Research Centres BIOSS and CIBSS, University of Freiburg, 79104 Freiburg, Germany.; Faculty of Biology, Cell Biology, University of Freiburg, 79104 Freiburg, Germany., Groß CJ; Signalling Research Centres BIOSS and CIBSS, University of Freiburg, 79104 Freiburg, Germany., Jost PJ; Division of Clinical Oncology, Department of Medicine, Medical University of Graz, 8036 Graz, Austria., Groß O; Institute of Neuropathology, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany.; Signalling Research Centres BIOSS and CIBSS, University of Freiburg, 79104 Freiburg, Germany.; Center for Basics in NeuroModulation (NeuroModulBasics), Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany.

المصدر: Science signaling [Sci Signal] 2023 Jan 17; Vol. 16 (768), pp. eabh1083. Date of Electronic Publication: 2023 Jan 17.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101465400 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1937-9145 (Electronic) Linking ISSN: 19450877 NLM ISO Abbreviation: Sci Signal Subsets: MEDLINE

مواضيع طبية MeSH: Inflammasomes*/metabolism , NLR Family, Pyrin Domain-Containing 3 Protein*/metabolism, Mice ; Animals ; Tyrosine Kinase Inhibitors ; Imatinib Mesylate ; Leukocytes, Mononuclear/metabolism ; Cell Death ; Myeloid Cells/metabolism ; Interleukin-1beta/metabolism

المؤلفون: Saller BS; Faculty of Medicine, Institute of Neuropathology, Medical Center - University of Freiburg, Freiburg, Germany.; Faculty of Biology, University of Freiburg, Freiburg, Germany., Neuwirt E; Faculty of Medicine, Institute of Neuropathology, Medical Center - University of Freiburg, Freiburg, Germany.; Faculty of Biology, University of Freiburg, Freiburg, Germany.; Signalling Research Centres BIOSS and CIBSS, University of Freiburg, Freiburg, Germany., Groß O; Faculty of Medicine, Institute of Neuropathology, Medical Center - University of Freiburg, Freiburg, Germany. olaf.gross@uniklinik-freiburg.de.; Signalling Research Centres BIOSS and CIBSS, University of Freiburg, Freiburg, Germany. olaf.gross@uniklinik-freiburg.de.; Faculty of Medicine, Center for Basics in NeuroModulation (NeuroModulBasics), University of Freiburg, Freiburg, Germany. olaf.gross@uniklinik-freiburg.de.

المصدر: Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2023; Vol. 2696, pp. 169-197.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Humana Press Country of Publication: United States NLM ID: 9214969 Publication Model: Print Cited Medium: Internet ISSN: 1940-6029 (Electronic) Linking ISSN: 10643745 NLM ISO Abbreviation: Methods Mol Biol Subsets: MEDLINE

مواضيع طبية MeSH: Inflammasomes*/metabolism , NLR Family, Pyrin Domain-Containing 3 Protein*/metabolism, Mice ; Humans ; Animals ; Leukocytes, Mononuclear/metabolism ; Caspase 1/metabolism ; Interleukin-1 ; Interleukin-1beta/metabolism

المؤلفون: Merz J; Department of Cardiology and Angiology I, Heart Center Freiburg University, Faculty of Medicine, University of Freiburg, Hugstetter Str. 55, 79106, Freiburg, Germany., Nettesheim A; Department of Cardiology and Angiology I, Heart Center Freiburg University, Faculty of Medicine, University of Freiburg, Hugstetter Str. 55, 79106, Freiburg, Germany., von Garlen S; Department of Cardiology and Angiology I, Heart Center Freiburg University, Faculty of Medicine, University of Freiburg, Hugstetter Str. 55, 79106, Freiburg, Germany., Albrecht P; Department of Cardiology and Angiology I, Heart Center Freiburg University, Faculty of Medicine, University of Freiburg, Hugstetter Str. 55, 79106, Freiburg, Germany., Saller BS; Institute of Neuropathology, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, 79106, Freiburg, Germany.; Faculty of Biology, University of Freiburg, 79104, Freiburg, Germany., Engelmann J; Department of Cardiology and Angiology I, Heart Center Freiburg University, Faculty of Medicine, University of Freiburg, Hugstetter Str. 55, 79106, Freiburg, Germany., Hertle L; Department of Cardiology and Angiology I, Heart Center Freiburg University, Faculty of Medicine, University of Freiburg, Hugstetter Str. 55, 79106, Freiburg, Germany., Schäfer I; Department of Cardiology and Angiology I, Heart Center Freiburg University, Faculty of Medicine, University of Freiburg, Hugstetter Str. 55, 79106, Freiburg, Germany., Dimanski D; Department of Cardiology and Angiology I, Heart Center Freiburg University, Faculty of Medicine, University of Freiburg, Hugstetter Str. 55, 79106, Freiburg, Germany., König S; Department of Cardiology and Angiology I, Heart Center Freiburg University, Faculty of Medicine, University of Freiburg, Hugstetter Str. 55, 79106, Freiburg, Germany., Karnbrock L; Department of Cardiology and Angiology I, Heart Center Freiburg University, Faculty of Medicine, University of Freiburg, Hugstetter Str. 55, 79106, Freiburg, Germany., Bulatova K; Department of Cardiology and Angiology I, Heart Center Freiburg University, Faculty of Medicine, University of Freiburg, Hugstetter Str. 55, 79106, Freiburg, Germany., Peikert A; Department of Cardiology and Angiology I, Heart Center Freiburg University, Faculty of Medicine, University of Freiburg, Hugstetter Str. 55, 79106, Freiburg, Germany., Hoppe N; Department of Cardiology and Angiology I, Heart Center Freiburg University, Faculty of Medicine, University of Freiburg, Hugstetter Str. 55, 79106, Freiburg, Germany., Hilgendorf I; Department of Cardiology and Angiology I, Heart Center Freiburg University, Faculty of Medicine, University of Freiburg, Hugstetter Str. 55, 79106, Freiburg, Germany., von Zur Mühlen C; Department of Cardiology and Angiology I, Heart Center Freiburg University, Faculty of Medicine, University of Freiburg, Hugstetter Str. 55, 79106, Freiburg, Germany., Wolf D; Department of Cardiology and Angiology I, Heart Center Freiburg University, Faculty of Medicine, University of Freiburg, Hugstetter Str. 55, 79106, Freiburg, Germany., Groß O; Institute of Neuropathology, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, 79106, Freiburg, Germany.; Faculty of Biology, University of Freiburg, 79104, Freiburg, Germany.; Signalling Research Centres BIOSS and CIBSS, University of Freiburg, 79104, Freiburg, Germany.; Center for Basics in NeuroModulation (NeuroModulBasics), Faculty of Medicine, University of Freiburg, 79106, Freiburg, Germany., Bode C; Department of Cardiology and Angiology I, Heart Center Freiburg University, Faculty of Medicine, University of Freiburg, Hugstetter Str. 55, 79106, Freiburg, Germany., Zirlik A; Department of Cardiology, University Hospital Graz, Graz, Austria., Stachon P; Department of Cardiology and Angiology I, Heart Center Freiburg University, Faculty of Medicine, University of Freiburg, Hugstetter Str. 55, 79106, Freiburg, Germany. peter.stachon@universitaets-herzzentrum.de.

المصدر: Purinergic signalling [Purinergic Signal] 2021 Sep; Vol. 17 (3), pp. 481-492. Date of Electronic Publication: 2021 Jul 20.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Springer Country of Publication: Netherlands NLM ID: 101250499 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-9546 (Electronic) Linking ISSN: 15739538 NLM ISO Abbreviation: Purinergic Signal Subsets: MEDLINE

مواضيع طبية MeSH: Inflammation Mediators/*metabolism , Macrophages/*metabolism , Receptors, Purinergic/*biosynthesis , Transcriptome/*physiology, Animals ; Cell Polarity/physiology ; Cells, Cultured ; Mice ; Receptors, Purinergic/genetics

المؤلفون: Neuwirt E; Institute of Neuropathology, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany; CIBSS - Centre for Integrative Biological Signalling Studies, University of Freiburg, 79104 Freiburg, Germany; Faculty of Biology, University of Freiburg, 79104 Freiburg, Germany., Gorka O; Institute of Neuropathology, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany., Saller BS; Institute of Neuropathology, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany; Faculty of Biology, University of Freiburg, 79104 Freiburg, Germany., Groß CJ; CIBSS - Centre for Integrative Biological Signalling Studies, University of Freiburg, 79104 Freiburg, Germany., Madl T; Gottfried Schatz Research Center for Cell Signaling, Metabolism and Aging, Molecular Biology & Biochemistry, Medical University of Graz, Graz 8010, Austria; BioTechMed-Graz, Graz 8010, Austria., Groß O; Institute of Neuropathology, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany; CIBSS - Centre for Integrative Biological Signalling Studies, University of Freiburg, 79104 Freiburg, Germany. Electronic address: olaf.gross@uniklinik-freiburg.de.

المصدر: Current opinion in biotechnology [Curr Opin Biotechnol] 2021 Apr; Vol. 68, pp. 300-309. Date of Electronic Publication: 2021 Apr 13.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Review

بيانات الدورية: Publisher: Elsevier Country of Publication: England NLM ID: 9100492 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0429 (Electronic) Linking ISSN: 09581669 NLM ISO Abbreviation: Curr Opin Biotechnol Subsets: MEDLINE

مواضيع طبية MeSH: Inflammasomes* , NLR Family, Pyrin Domain-Containing 3 Protein*/genetics, Humans ; Immunity, Innate ; Inflammation

المؤلفون: Hamarsheh S; Department of Medicine I, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Faculty of Biology, University of Freiburg, Freiburg, Germany., Osswald L; Department of Medicine I, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Saller BS; Faculty of Biology, University of Freiburg, Freiburg, Germany.; Institute of Neuropathology, University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Unger S; Institute of Experimental Immunology, University of Zurich, Zurich, Switzerland., De Feo D; Institute of Experimental Immunology, University of Zurich, Zurich, Switzerland., Vinnakota JM; Department of Medicine I, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Faculty of Biology, University of Freiburg, Freiburg, Germany., Konantz M; Department of Biomedicine, University of Basel and University Hospital Basel, Basel, Switzerland., Uhl FM; Department of Medicine I, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Faculty of Biology, University of Freiburg, Freiburg, Germany., Becker H; Department of Medicine I, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Lübbert M; Department of Medicine I, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Shoumariyeh K; Department of Medicine I, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Schürch C; Department of Biomedicine, University of Basel and University Hospital Basel, Basel, Switzerland., Andrieux G; Institute of Medical Bioinformatics and Systems Medicine, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Venhoff N; Clinic for Rheumatology and Clinical Immunology, University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Schmitt-Graeff A; University of Freiburg, Freiburg, Germany., Duquesne S; Department of Medicine I, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Pfeifer D; Department of Medicine I, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Cooper MA; Institute for Molecular Bioscience, University of Queensland, Brisbane, Australia., Lengerke C; Department of Biomedicine, University of Basel and University Hospital Basel, Basel, Switzerland., Boerries M; Institute of Medical Bioinformatics and Systems Medicine, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; German Cancer Consortium (DKTK) Partner Site Freiburg, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Comprehensive Cancer Centre Freiburg (CCCF), University of Freiburg, Freiburg, Germany., Duyster J; Department of Medicine I, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; German Cancer Consortium (DKTK) Partner Site Freiburg, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Comprehensive Cancer Centre Freiburg (CCCF), University of Freiburg, Freiburg, Germany., Niemeyer CM; German Cancer Consortium (DKTK) Partner Site Freiburg, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Comprehensive Cancer Centre Freiburg (CCCF), University of Freiburg, Freiburg, Germany.; Division of Pediatric Hematology and Oncology, Department of Pediatrics and Adolescent Medicine, University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Erlacher M; German Cancer Consortium (DKTK) Partner Site Freiburg, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Comprehensive Cancer Centre Freiburg (CCCF), University of Freiburg, Freiburg, Germany.; Division of Pediatric Hematology and Oncology, Department of Pediatrics and Adolescent Medicine, University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Blazar BR; Division of Blood and Marrow Transplantation, Department of Pediatrics, Masonic Cancer Center, University of Minnesota, Minneapolis, MN, 55455, USA., Becher B; Institute of Experimental Immunology, University of Zurich, Zurich, Switzerland., Groß O; Institute of Neuropathology, University Medical Center Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Centre for Biological Signalling Studies (BIOSS) and Centre for Integrative Biological Signalling Studies (CIBSS), University of Freiburg, Freiburg, Germany., Brummer T; German Cancer Consortium (DKTK) Partner Site Freiburg, German Cancer Research Center (DKFZ), Heidelberg, Germany.; Comprehensive Cancer Centre Freiburg (CCCF), University of Freiburg, Freiburg, Germany.; Institute of Molecular Medicine and Cell Research (IMMZ), Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Centre for Biological Signalling Studies (BIOSS), University of Freiburg, Freiburg, Germany., Zeiser R; Department of Medicine I, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany. robert.zeiser@uniklinik-freiburg.de.; German Cancer Consortium (DKTK) Partner Site Freiburg, German Cancer Research Center (DKFZ), Heidelberg, Germany. robert.zeiser@uniklinik-freiburg.de.; Comprehensive Cancer Centre Freiburg (CCCF), University of Freiburg, Freiburg, Germany. robert.zeiser@uniklinik-freiburg.de.; Centre for Biological Signalling Studies (BIOSS) and Centre for Integrative Biological Signalling Studies (CIBSS), University of Freiburg, Freiburg, Germany. robert.zeiser@uniklinik-freiburg.de.

المصدر: Nature communications [Nat Commun] 2020 Apr 03; Vol. 11 (1), pp. 1659. Date of Electronic Publication: 2020 Apr 03.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Inflammasomes/*immunology , Myeloproliferative Disorders/*genetics , NLR Family, Pyrin Domain-Containing 3 Protein/*metabolism , Proto-Oncogene Proteins p21(ras)/*genetics, Animals ; Cell Proliferation ; Gene Expression ; Hematopoiesis ; Humans ; Inflammasomes/metabolism ; Interleukin-1beta/metabolism ; Leukemia, Myeloid/etiology ; Leukemia, Myeloid/genetics ; Mice ; Mice, Inbred C57BL ; Molecular Targeted Therapy ; Myeloid Cells/metabolism ; NLR Proteins/metabolism ; Proto-Oncogene Proteins p21(ras)/metabolism ; Reactive Oxygen Species/metabolism ; Signal Transduction

المؤلفون: Rieblinger B; Chair of Livestock Biotechnology, School of Life Sciences Weihenstephan, Technische Universität München, Freising, Germany., Fischer K; Chair of Livestock Biotechnology, School of Life Sciences Weihenstephan, Technische Universität München, Freising, Germany., Kind A; Chair of Livestock Biotechnology, School of Life Sciences Weihenstephan, Technische Universität München, Freising, Germany., Saller BS; Chair of Livestock Biotechnology, School of Life Sciences Weihenstephan, Technische Universität München, Freising, Germany., Baars W; Transplant Laboratory, Department for General-, Visceral- and Transplantation Surgery, Hannover Medical School, Hannover, Germany., Schuster M; Medizinische Klinik and Polyklinik IV, Diabetes Zentrum, Klinikum der Ludwig-Maximilians-Universität München, Munich, Germany., Wolf-van Buerck L; Medizinische Klinik and Polyklinik IV, Diabetes Zentrum, Klinikum der Ludwig-Maximilians-Universität München, Munich, Germany., Schäffler A; Chair of Livestock Biotechnology, School of Life Sciences Weihenstephan, Technische Universität München, Freising, Germany., Flisikowska T; Chair of Livestock Biotechnology, School of Life Sciences Weihenstephan, Technische Universität München, Freising, Germany., Kurome M; Chair of Molecular Animal Breeding and Biotechnology, Ludwig-Maximilians-Universität München, Oberschleissheim, Germany., Zakhartchenko V; Chair of Molecular Animal Breeding and Biotechnology, Ludwig-Maximilians-Universität München, Oberschleissheim, Germany., Kessler B; Chair of Molecular Animal Breeding and Biotechnology, Ludwig-Maximilians-Universität München, Oberschleissheim, Germany., Flisikowski K; Chair of Livestock Biotechnology, School of Life Sciences Weihenstephan, Technische Universität München, Freising, Germany., Wolf E; Chair of Molecular Animal Breeding and Biotechnology, Ludwig-Maximilians-Universität München, Oberschleissheim, Germany., Seissler J; Medizinische Klinik and Polyklinik IV, Diabetes Zentrum, Klinikum der Ludwig-Maximilians-Universität München, Munich, Germany., Schwinzer R; Transplant Laboratory, Department for General-, Visceral- and Transplantation Surgery, Hannover Medical School, Hannover, Germany., Schnieke A; Chair of Livestock Biotechnology, School of Life Sciences Weihenstephan, Technische Universität München, Freising, Germany.

المصدر: Xenotransplantation [Xenotransplantation] 2018 Mar; Vol. 25 (2), pp. e12382. Date of Electronic Publication: 2018 Jan 23.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Munksgaard International Publishers Country of Publication: Denmark NLM ID: 9438793 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1399-3089 (Electronic) Linking ISSN: 0908665X NLM ISO Abbreviation: Xenotransplantation Subsets: MEDLINE

مواضيع طبية MeSH: Transplantation, Heterologous*/methods, Insulin-Secreting Cells/*cytology, Animals ; Animals, Genetically Modified/genetics ; CD55 Antigens/genetics ; CD59 Antigens/genetics ; Fibroblasts/cytology ; Genetic Loci ; Heme Oxygenase-1/genetics ; Humans ; Promoter Regions, Genetic/genetics ; Swine ; Transgenes/genetics

المؤلفون: Schneider KS; Institute of Clinical Chemistry and Pathobiochemistry, Klinikum rechts der Isar, School of Medicine, Technical University of Munich, 81675 Munich, Germany., Groß CJ; Institute of Clinical Chemistry and Pathobiochemistry, Klinikum rechts der Isar, School of Medicine, Technical University of Munich, 81675 Munich, Germany; BIOSS Centre for Biological Signaling Studies, University of Freiburg, 79104 Freiburg, Germany., Dreier RF; Focal Area Infection Biology, Biozentrum, University of Basel, 4056 Basel, Switzerland., Saller BS; Institute of Neuropathology, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany., Mishra R; Institute of Clinical Chemistry and Pathobiochemistry, Klinikum rechts der Isar, School of Medicine, Technical University of Munich, 81675 Munich, Germany; Center for Translational Cancer Research (TranslaTUM), Technical University of Munich, 81675 Munich, Germany., Gorka O; Institute of Neuropathology, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany., Heilig R; Focal Area Infection Biology, Biozentrum, University of Basel, 4056 Basel, Switzerland., Meunier E; Focal Area Infection Biology, Biozentrum, University of Basel, 4056 Basel, Switzerland., Dick MS; Focal Area Infection Biology, Biozentrum, University of Basel, 4056 Basel, Switzerland., Ćiković T; Institute of Clinical Chemistry and Pathobiochemistry, Klinikum rechts der Isar, School of Medicine, Technical University of Munich, 81675 Munich, Germany; Center for Translational Cancer Research (TranslaTUM), Technical University of Munich, 81675 Munich, Germany., Sodenkamp J; Institute of Clinical Chemistry and Pathobiochemistry, Klinikum rechts der Isar, School of Medicine, Technical University of Munich, 81675 Munich, Germany; Center for Translational Cancer Research (TranslaTUM), Technical University of Munich, 81675 Munich, Germany; German Cancer Consortium (DKTK), Partner Site Munich, 80336 Munich, Germany., Médard G; Chair of Proteomics and Bioanalytics, Technical University of Munich, 85354 Freising, Germany., Naumann R; Max Planck Institute of Molecular Cell Biology and Genetics, 01307 Dresden, Germany., Ruland J; Institute of Clinical Chemistry and Pathobiochemistry, Klinikum rechts der Isar, School of Medicine, Technical University of Munich, 81675 Munich, Germany; Center for Translational Cancer Research (TranslaTUM), Technical University of Munich, 81675 Munich, Germany; German Cancer Consortium (DKTK), Partner Site Munich, 80336 Munich, Germany; German Center for Infection Research (DZIF), partner site Munich, 81675 Munich, Germany., Kuster B; Chair of Proteomics and Bioanalytics, Technical University of Munich, 85354 Freising, Germany; Center for Integrated Protein Science Munich (CIPSM), 81377 Munich, Germany., Broz P; Focal Area Infection Biology, Biozentrum, University of Basel, 4056 Basel, Switzerland; Department of Biochemistry, University of Lausanne, 1066 Epalinges, Switzerland., Groß O; Institute of Clinical Chemistry and Pathobiochemistry, Klinikum rechts der Isar, School of Medicine, Technical University of Munich, 81675 Munich, Germany; BIOSS Centre for Biological Signaling Studies, University of Freiburg, 79104 Freiburg, Germany; Institute of Neuropathology, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany; Center for Translational Cancer Research (TranslaTUM), Technical University of Munich, 81675 Munich, Germany. Electronic address: olaf.gross@uniklinik-freiburg.de.

المصدر: Cell reports [Cell Rep] 2017 Dec 26; Vol. 21 (13), pp. 3846-3859.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE

مواضيع طبية MeSH: Pyroptosis*/drug effects, Apoptosis Regulatory Proteins/*metabolism , Caspase 1/*metabolism , Inflammasomes/*metabolism , Interleukin-1/*metabolism, Animals ; Caspase 8/metabolism ; Caspase Inhibitors/pharmacology ; Enzyme Activation/drug effects ; Francisella/physiology ; Immunity, Innate ; Interleukin-1beta/metabolism ; Intracellular Signaling Peptides and Proteins ; Mice, Inbred C57BL ; Phosphate-Binding Proteins