يعرض 1 - 10 نتائج من 36 نتيجة بحث عن '"Sam Agresta"', وقت الاستعلام: 1.09s تنقيح النتائج
  1. 1
    Supplementary Table 3 from Circulating Oncometabolite 2-Hydroxyglutarate Is a Potential Surrogate Biomarker in Patients with Isocitrate Dehydrogenase-Mutant Intrahepatic Cholangiocarcinoma

    المؤلفون: Andrew X. Zhu, David P. Ryan, Leif W. Ellisen, David P. Schenkein, Sam Agresta, Kimberly S. Straley, Nabeel Bardeesy, Kenneth K. Tanabe, Cristina R. Ferrone, Jennifer Y. Wo, Theodore S. Hong, Supriya K. Saha, Janet E. Murphy, Lawrence S. Blaszkowsky, Jill N. Allen, Jeffrey W. Clark, Eunice L. Kwak, A. John Iafrate, Jason E. Faris, Katharine Yen, Hyeryun Kim, Hua Yang, Hannah M. Liebman, David C. Christiani, Vikram Deshpande, Marek Ancukiewicz, Ronnie T. Poon, Thomas Yau, Lipika Goyal, Darrell R. Borger

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a53a615740a867e6636275cab9cd0e84
    https://doi.org/10.1158/1078-0432.22451921.v1

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  2. 2
    Supplementary Table 2 from Circulating Oncometabolite 2-Hydroxyglutarate Is a Potential Surrogate Biomarker in Patients with Isocitrate Dehydrogenase-Mutant Intrahepatic Cholangiocarcinoma

    المؤلفون: Andrew X. Zhu, David P. Ryan, Leif W. Ellisen, David P. Schenkein, Sam Agresta, Kimberly S. Straley, Nabeel Bardeesy, Kenneth K. Tanabe, Cristina R. Ferrone, Jennifer Y. Wo, Theodore S. Hong, Supriya K. Saha, Janet E. Murphy, Lawrence S. Blaszkowsky, Jill N. Allen, Jeffrey W. Clark, Eunice L. Kwak, A. John Iafrate, Jason E. Faris, Katharine Yen, Hyeryun Kim, Hua Yang, Hannah M. Liebman, David C. Christiani, Vikram Deshpande, Marek Ancukiewicz, Ronnie T. Poon, Thomas Yau, Lipika Goyal, Darrell R. Borger

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43bac6ecbee16339e3de1293f2ad4a6e
    https://doi.org/10.1158/1078-0432.22451924.v1

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  3. 3
    Supplementary Table 1 from Circulating Oncometabolite 2-Hydroxyglutarate Is a Potential Surrogate Biomarker in Patients with Isocitrate Dehydrogenase-Mutant Intrahepatic Cholangiocarcinoma

    المؤلفون: Andrew X. Zhu, David P. Ryan, Leif W. Ellisen, David P. Schenkein, Sam Agresta, Kimberly S. Straley, Nabeel Bardeesy, Kenneth K. Tanabe, Cristina R. Ferrone, Jennifer Y. Wo, Theodore S. Hong, Supriya K. Saha, Janet E. Murphy, Lawrence S. Blaszkowsky, Jill N. Allen, Jeffrey W. Clark, Eunice L. Kwak, A. John Iafrate, Jason E. Faris, Katharine Yen, Hyeryun Kim, Hua Yang, Hannah M. Liebman, David C. Christiani, Vikram Deshpande, Marek Ancukiewicz, Ronnie T. Poon, Thomas Yau, Lipika Goyal, Darrell R. Borger

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34aba81d9008324039d75f09f39f9871
    https://doi.org/10.1158/1078-0432.22451927

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  4. 4
    Abstract 2122: The dual BRM/BRG1 (SMARCA2/4) inhibitor FHD-286 induces differentiation in preclinical models of AML

    المؤلفون: Mike Collins, Astrid Thomsen, Ashley Gartin, Gabriel J. Sandoval, Ammar Adam, Sarah Reilly, Laure Delestre, Virginie Penard-Lacronique, Warren Fiskus, Kapil Bhalla, Stephane de Botton, Sam Agresta, Jessica Piel, Murphy Hentemann

    المصدر: Cancer Research. 83:2122-2122

    مصطلحات موضوعية: Cancer Research, Oncology

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::2fa0e19437e23840a152393207b50e1a
    https://doi.org/10.1158/1538-7445.am2023-2122

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  5. 5
    Clinical pharmacokinetics and pharmacodynamics of ivosidenib, an oral, targeted inhibitor of mutant IDH1, in patients with advanced solid tumors

    المؤلفون: David Dai, Shuchi Sumant Pandya, Ingo K. Mellinghoff, Maeve A. Lowery, Erika Manyak, Patrick Y. Wen, Bin Fan, Lipika Goyal, Molly Prahl Judge, Sam Agresta, Tara Nimkar, Liewen Jiang, Guowen Liu, William D. Tap, Hua Yang, Camelia Gliser

    المصدر: Investigational New Drugs

    مصطلحات موضوعية: 0301 basic medicine, Adult, Male, IDH1, Pyridines, Glycine, 2-hydroxyglutarate, Administration, Oral, Antineoplastic Agents, Pharmacology, IDH2, Glutarates, 03 medical and health sciences, 0302 clinical medicine, Pharmacokinetics, Glioma, Phase I Studies, Neoplasms, medicine, Humans, Pharmacology (medical), Aged, Aged, 80 and over, CYP3A4, Dose-Response Relationship, Drug, business.industry, Isocitrate dehydrogenase 1 inhibitor, Middle Aged, medicine.disease, Isocitrate Dehydrogenase, 030104 developmental biology, Oncology, Ivosidenib, Pharmacodynamics, 030220 oncology & carcinogenesis, Concomitant, Mutation, Female, Chondrosarcoma, business

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cb8d1211dda7c32ea032d7647d9a74a
    http://europepmc.org/articles/PMC7066280

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  6. 6
    Pharmacokinetics, absorption, metabolism, and excretion of [14C]ivosidenib (AG-120) in healthy male subjects

    المؤلفون: Syed Altaf, Hua Liu, Chandra Prakash, Hua Yang, Sam Agresta, Bin Fan

    المصدر: Cancer Chemotherapy and Pharmacology. 83:837-848

    مصطلحات موضوعية: 0301 basic medicine, Pharmacology, Cancer Research, Chromatography, biology, Chemistry, Cytochrome P450, Metabolism, Absorption (skin), Urine, Toxicology, High-performance liquid chromatography, Excretion, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Oncology, Pharmacokinetics, 030220 oncology & carcinogenesis, biology.protein, Pharmacology (medical), Feces

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::7c0c5b0b67775cdf51fe6c278f402f3c
    https://doi.org/10.1007/s00280-019-03793-7

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  7. 7
    Isocitrate dehydrogenase 1 and 2 mutations, 2‐hydroxyglutarate levels, and response to standard chemotherapy for patients with newly diagnosed acute myeloid leukemia

    المؤلفون: Yi-Bin Chen, Gabriela S. Hobbs, Meghan Burke, Philip C. Amrein, Seth A. Wander, Ilene Galinsky, Donna Neuberg, Christelle Joseph, Darrell R. Borger, Kimberly Straley, Aura Y. Ramos, Richard Stone, Hua Yang, Eyal C. Attar, Karen K. Ballen, Hossein Sadrzadeh, Sam Agresta, Ashley M. Perry, Andrew M. Brunner, Katharine E. Yen, Timothy A. Graubert, Anthony J. Iafrate, Amir T. Fathi, Christine Connolly, Sophia Adamia

    المصدر: Cancer. 125:541-549

    مصطلحات موضوعية: Adult, Male, Cancer Research, medicine.medical_specialty, IDH1, medicine.medical_treatment, Gastroenterology, IDH2, Glutarates, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, Antineoplastic Combined Chemotherapy Protocols, Biomarkers, Tumor, medicine, Humans, Prospective Studies, 030212 general & internal medicine, Aged, Aged, 80 and over, Chemotherapy, business.industry, Proportional hazards model, Myeloid leukemia, Middle Aged, Prognosis, Isocitrate Dehydrogenase, Survival Rate, Leukemia, Myeloid, Acute, Exact test, medicine.anatomical_structure, Isocitrate dehydrogenase, Oncology, 030220 oncology & carcinogenesis, Mutation, Female, Bone marrow, business, Follow-Up Studies

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1e9a13f69e5723d802788b9dbec963a
    https://doi.org/10.1002/cncr.31729

    View record at Wiley
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  8. 8
    Phase I Study of the Mutant IDH1 Inhibitor Ivosidenib: Safety and Clinical Activity in Patients With Advanced Chondrosarcoma

    المؤلفون: Liewen Jiang, Andrew J. Wagner, Sung Choe, Shuchi Sumant Pandya, Murali Beeram, Bin Wu, Katharine E. Yen, Howard A. Burris, Sam Agresta, Gregory M. Cote, Jonathan C. Trent, Filip Janku, William D. Tap, Victor M. Villalobos, Olivier Mir, Camelia Gliser, Bin Fan

    المصدر: J Clin Oncol

    مصطلحات موضوعية: 0301 basic medicine, Adult, Male, Cancer Research, IDH1, Pyridines, Mutant, Chondrosarcoma, Glycine, Disease, Systemic therapy, 03 medical and health sciences, 0302 clinical medicine, Medicine, Humans, In patient, Enzyme Inhibitors, Aged, Aged, 80 and over, business.industry, Localized Chondrosarcoma, ORIGINAL REPORTS, Middle Aged, medicine.disease, Phase i study, 030104 developmental biology, Oncology, 030220 oncology & carcinogenesis, Cancer research, Female, business

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09714879d065e68d645855939462df06
    https://europepmc.org/articles/PMC7238491/

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  9. 9
    Clonal heterogeneity of acute myeloid leukemia treated with the IDH2 inhibitor enasidenib

    المؤلفون: George S. Vassiliou, Eytan M. Stein, Cyril Quivoron, Ross L. Levine, Lynn Quek, Stéphane de Botton, Paresh Vyas, Bilyana Stoilova, Michael Amatangelo, Alison Kennedy, M. S. Vijayabaskar, Alan Shih, O. Bernard, Virginie Penard-Lacronique, Katharine E. Yen, Véronique Saada, Maël Heiblig, Samar Alsafadi, Marlen Metzner, Kyle J. MacBeth, Muriel D. David, Andy Peniket, Anjan Thakurta, Sam Agresta, Christophe Willekens

    المصدر: Quek, L, David, M D, Kennedy, A, Metzner, M, Amatangelo, M, Shih, A, Stoilova, B, Quivoron, C, Heiblig, M, Willekens, C, Saada, V, Alsafadi, S, Vijayabaskar, M S, Peniket, A, Bernard, O A, Agresta, S, Yen, K, MacBeth, K, Stein, E, Vassiliou, G S, Levine, R, De Botton, S, Thakurta, A, Penard-Lacronique, V & Vyas, P 2018, ' Clonal heterogeneity of acute myeloid leukemia treated with the IDH2 inhibitor enasidenib ', Nature Medicine, vol. 24, no. 8, pp. 1167-1177 . https://doi.org/10.1038/s41591-018-0115-6

    مصطلحات موضوعية: Neoplastic Stem Cells/drug effects, 0301 basic medicine, Myeloid, Mutation/genetics, Cellular differentiation, Leukemia, Myeloid, Acute/drug therapy, Aminopyridines, Enasidenib, Biology, Somatic evolution in cancer, General Biochemistry, Genetics and Molecular Biology, Immunophenotyping, Cohort Studies, 03 medical and health sciences, 0302 clinical medicine, medicine, Humans, Neoplasm Recurrence, Local/pathology, Triazines, Myeloid leukemia, Cell Differentiation, General Medicine, medicine.disease, Isocitrate Dehydrogenase, Clone Cells, Hematopoiesis, Aminopyridines/pharmacology, Leukemia, Myeloid, Acute, Leukemia, Haematopoiesis, Triazines/pharmacology, 030104 developmental biology, medicine.anatomical_structure, Cell Differentiation/drug effects, 030220 oncology & carcinogenesis, Isocitrate Dehydrogenase/antagonists & inhibitors, Mutation, Neoplastic Stem Cells, Cancer research, Neoplasm Recurrence, Local

    وصف الملف: application/pdf

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d30ad4500bdf6ee72adaf9de1577627
    https://doi.org/10.1038/s41591-018-0115-6

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  10. 10
    Enasidenib in mutant IDH2 relapsed or refractory acute myeloid leukemia

    المؤلفون: Daniel A. Pollyea, Gail J. Roboz, Anthony S. Stein, Robert H. Collins, Daniel J. DeAngelo, Manish R. Patel, Mikkael A. Sekeres, Eytan M. Stein, Sam Agresta, Courtney D. DiNardo, Ronan T. Swords, Richard Stone, Arthur E. Frankel, Ross L. Levine, Qiang Xu, Amir T. Fathi, Martin S. Tallman, Ian W. Flinn, Hagop M. Kantarjian, Alessandra Tosolini, Bruno C. Medeiros, Stéphane de Botton, Christophe Willekens, Katharine E. Yen, Jessica K. Altman, Paresh Vyas, Robert Knight

    مصطلحات موضوعية: 0301 basic medicine, Oncology, medicine.medical_specialty, Myeloid, Immunology, Pharmacology, Enasidenib, Biochemistry, IDH2, 03 medical and health sciences, 0302 clinical medicine, Refractory, Internal medicine, Medicine, Adverse effect, business.industry, Myeloid leukemia, Cell Biology, Hematology, medicine.disease, Leukemia, 030104 developmental biology, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Pharmacodynamics, business

    URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::816a6dbec3f4f3b42c9868d8d7fe8d39
    https://doi.org/10.1182/blood-2017-04-779405

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