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المؤلفون: Andrew X. Zhu, David P. Ryan, Leif W. Ellisen, David P. Schenkein, Sam Agresta, Kimberly S. Straley, Nabeel Bardeesy, Kenneth K. Tanabe, Cristina R. Ferrone, Jennifer Y. Wo, Theodore S. Hong, Supriya K. Saha, Janet E. Murphy, Lawrence S. Blaszkowsky, Jill N. Allen, Jeffrey W. Clark, Eunice L. Kwak, A. John Iafrate, Jason E. Faris, Katharine Yen, Hyeryun Kim, Hua Yang, Hannah M. Liebman, David C. Christiani, Vikram Deshpande, Marek Ancukiewicz, Ronnie T. Poon, Thomas Yau, Lipika Goyal, Darrell R. Borger
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a53a615740a867e6636275cab9cd0e84
https://doi.org/10.1158/1078-0432.22451921.v1 -
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المؤلفون: Andrew X. Zhu, David P. Ryan, Leif W. Ellisen, David P. Schenkein, Sam Agresta, Kimberly S. Straley, Nabeel Bardeesy, Kenneth K. Tanabe, Cristina R. Ferrone, Jennifer Y. Wo, Theodore S. Hong, Supriya K. Saha, Janet E. Murphy, Lawrence S. Blaszkowsky, Jill N. Allen, Jeffrey W. Clark, Eunice L. Kwak, A. John Iafrate, Jason E. Faris, Katharine Yen, Hyeryun Kim, Hua Yang, Hannah M. Liebman, David C. Christiani, Vikram Deshpande, Marek Ancukiewicz, Ronnie T. Poon, Thomas Yau, Lipika Goyal, Darrell R. Borger
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43bac6ecbee16339e3de1293f2ad4a6e
https://doi.org/10.1158/1078-0432.22451924.v1 -
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المؤلفون: Andrew X. Zhu, David P. Ryan, Leif W. Ellisen, David P. Schenkein, Sam Agresta, Kimberly S. Straley, Nabeel Bardeesy, Kenneth K. Tanabe, Cristina R. Ferrone, Jennifer Y. Wo, Theodore S. Hong, Supriya K. Saha, Janet E. Murphy, Lawrence S. Blaszkowsky, Jill N. Allen, Jeffrey W. Clark, Eunice L. Kwak, A. John Iafrate, Jason E. Faris, Katharine Yen, Hyeryun Kim, Hua Yang, Hannah M. Liebman, David C. Christiani, Vikram Deshpande, Marek Ancukiewicz, Ronnie T. Poon, Thomas Yau, Lipika Goyal, Darrell R. Borger
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34aba81d9008324039d75f09f39f9871
https://doi.org/10.1158/1078-0432.22451927 -
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المؤلفون: Mike Collins, Astrid Thomsen, Ashley Gartin, Gabriel J. Sandoval, Ammar Adam, Sarah Reilly, Laure Delestre, Virginie Penard-Lacronique, Warren Fiskus, Kapil Bhalla, Stephane de Botton, Sam Agresta, Jessica Piel, Murphy Hentemann
المصدر: Cancer Research. 83:2122-2122
مصطلحات موضوعية: Cancer Research, Oncology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::2fa0e19437e23840a152393207b50e1a
https://doi.org/10.1158/1538-7445.am2023-2122 -
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المؤلفون: David Dai, Shuchi Sumant Pandya, Ingo K. Mellinghoff, Maeve A. Lowery, Erika Manyak, Patrick Y. Wen, Bin Fan, Lipika Goyal, Molly Prahl Judge, Sam Agresta, Tara Nimkar, Liewen Jiang, Guowen Liu, William D. Tap, Hua Yang, Camelia Gliser
المصدر: Investigational New Drugs
مصطلحات موضوعية: 0301 basic medicine, Adult, Male, IDH1, Pyridines, Glycine, 2-hydroxyglutarate, Administration, Oral, Antineoplastic Agents, Pharmacology, IDH2, Glutarates, 03 medical and health sciences, 0302 clinical medicine, Pharmacokinetics, Glioma, Phase I Studies, Neoplasms, medicine, Humans, Pharmacology (medical), Aged, Aged, 80 and over, CYP3A4, Dose-Response Relationship, Drug, business.industry, Isocitrate dehydrogenase 1 inhibitor, Middle Aged, medicine.disease, Isocitrate Dehydrogenase, 030104 developmental biology, Oncology, Ivosidenib, Pharmacodynamics, 030220 oncology & carcinogenesis, Concomitant, Mutation, Female, Chondrosarcoma, business
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المؤلفون: Syed Altaf, Hua Liu, Chandra Prakash, Hua Yang, Sam Agresta, Bin Fan
المصدر: Cancer Chemotherapy and Pharmacology. 83:837-848
مصطلحات موضوعية: 0301 basic medicine, Pharmacology, Cancer Research, Chromatography, biology, Chemistry, Cytochrome P450, Metabolism, Absorption (skin), Urine, Toxicology, High-performance liquid chromatography, Excretion, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Oncology, Pharmacokinetics, 030220 oncology & carcinogenesis, biology.protein, Pharmacology (medical), Feces
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المؤلفون: Yi-Bin Chen, Gabriela S. Hobbs, Meghan Burke, Philip C. Amrein, Seth A. Wander, Ilene Galinsky, Donna Neuberg, Christelle Joseph, Darrell R. Borger, Kimberly Straley, Aura Y. Ramos, Richard Stone, Hua Yang, Eyal C. Attar, Karen K. Ballen, Hossein Sadrzadeh, Sam Agresta, Ashley M. Perry, Andrew M. Brunner, Katharine E. Yen, Timothy A. Graubert, Anthony J. Iafrate, Amir T. Fathi, Christine Connolly, Sophia Adamia
المصدر: Cancer. 125:541-549
مصطلحات موضوعية: Adult, Male, Cancer Research, medicine.medical_specialty, IDH1, medicine.medical_treatment, Gastroenterology, IDH2, Glutarates, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Internal medicine, Antineoplastic Combined Chemotherapy Protocols, Biomarkers, Tumor, medicine, Humans, Prospective Studies, 030212 general & internal medicine, Aged, Aged, 80 and over, Chemotherapy, business.industry, Proportional hazards model, Myeloid leukemia, Middle Aged, Prognosis, Isocitrate Dehydrogenase, Survival Rate, Leukemia, Myeloid, Acute, Exact test, medicine.anatomical_structure, Isocitrate dehydrogenase, Oncology, 030220 oncology & carcinogenesis, Mutation, Female, Bone marrow, business, Follow-Up Studies
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المؤلفون: Liewen Jiang, Andrew J. Wagner, Sung Choe, Shuchi Sumant Pandya, Murali Beeram, Bin Wu, Katharine E. Yen, Howard A. Burris, Sam Agresta, Gregory M. Cote, Jonathan C. Trent, Filip Janku, William D. Tap, Victor M. Villalobos, Olivier Mir, Camelia Gliser, Bin Fan
المصدر: J Clin Oncol
مصطلحات موضوعية: 0301 basic medicine, Adult, Male, Cancer Research, IDH1, Pyridines, Mutant, Chondrosarcoma, Glycine, Disease, Systemic therapy, 03 medical and health sciences, 0302 clinical medicine, Medicine, Humans, In patient, Enzyme Inhibitors, Aged, Aged, 80 and over, business.industry, Localized Chondrosarcoma, ORIGINAL REPORTS, Middle Aged, medicine.disease, Phase i study, 030104 developmental biology, Oncology, 030220 oncology & carcinogenesis, Cancer research, Female, business
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09714879d065e68d645855939462df06
https://europepmc.org/articles/PMC7238491/ -
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المؤلفون: George S. Vassiliou, Eytan M. Stein, Cyril Quivoron, Ross L. Levine, Lynn Quek, Stéphane de Botton, Paresh Vyas, Bilyana Stoilova, Michael Amatangelo, Alison Kennedy, M. S. Vijayabaskar, Alan Shih, O. Bernard, Virginie Penard-Lacronique, Katharine E. Yen, Véronique Saada, Maël Heiblig, Samar Alsafadi, Marlen Metzner, Kyle J. MacBeth, Muriel D. David, Andy Peniket, Anjan Thakurta, Sam Agresta, Christophe Willekens
المصدر: Quek, L, David, M D, Kennedy, A, Metzner, M, Amatangelo, M, Shih, A, Stoilova, B, Quivoron, C, Heiblig, M, Willekens, C, Saada, V, Alsafadi, S, Vijayabaskar, M S, Peniket, A, Bernard, O A, Agresta, S, Yen, K, MacBeth, K, Stein, E, Vassiliou, G S, Levine, R, De Botton, S, Thakurta, A, Penard-Lacronique, V & Vyas, P 2018, ' Clonal heterogeneity of acute myeloid leukemia treated with the IDH2 inhibitor enasidenib ', Nature Medicine, vol. 24, no. 8, pp. 1167-1177 . https://doi.org/10.1038/s41591-018-0115-6
مصطلحات موضوعية: Neoplastic Stem Cells/drug effects, 0301 basic medicine, Myeloid, Mutation/genetics, Cellular differentiation, Leukemia, Myeloid, Acute/drug therapy, Aminopyridines, Enasidenib, Biology, Somatic evolution in cancer, General Biochemistry, Genetics and Molecular Biology, Immunophenotyping, Cohort Studies, 03 medical and health sciences, 0302 clinical medicine, medicine, Humans, Neoplasm Recurrence, Local/pathology, Triazines, Myeloid leukemia, Cell Differentiation, General Medicine, medicine.disease, Isocitrate Dehydrogenase, Clone Cells, Hematopoiesis, Aminopyridines/pharmacology, Leukemia, Myeloid, Acute, Leukemia, Haematopoiesis, Triazines/pharmacology, 030104 developmental biology, medicine.anatomical_structure, Cell Differentiation/drug effects, 030220 oncology & carcinogenesis, Isocitrate Dehydrogenase/antagonists & inhibitors, Mutation, Neoplastic Stem Cells, Cancer research, Neoplasm Recurrence, Local
وصف الملف: application/pdf
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المؤلفون: Daniel A. Pollyea, Gail J. Roboz, Anthony S. Stein, Robert H. Collins, Daniel J. DeAngelo, Manish R. Patel, Mikkael A. Sekeres, Eytan M. Stein, Sam Agresta, Courtney D. DiNardo, Ronan T. Swords, Richard Stone, Arthur E. Frankel, Ross L. Levine, Qiang Xu, Amir T. Fathi, Martin S. Tallman, Ian W. Flinn, Hagop M. Kantarjian, Alessandra Tosolini, Bruno C. Medeiros, Stéphane de Botton, Christophe Willekens, Katharine E. Yen, Jessica K. Altman, Paresh Vyas, Robert Knight
مصطلحات موضوعية: 0301 basic medicine, Oncology, medicine.medical_specialty, Myeloid, Immunology, Pharmacology, Enasidenib, Biochemistry, IDH2, 03 medical and health sciences, 0302 clinical medicine, Refractory, Internal medicine, Medicine, Adverse effect, business.industry, Myeloid leukemia, Cell Biology, Hematology, medicine.disease, Leukemia, 030104 developmental biology, medicine.anatomical_structure, 030220 oncology & carcinogenesis, Pharmacodynamics, business
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::816a6dbec3f4f3b42c9868d8d7fe8d39
https://doi.org/10.1182/blood-2017-04-779405