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1
المؤلفون: Gavin W. Collie, Louise Barlind, Sana Bazzaz, Ulf Börjesson, Ian L. Dale, Jeremy S. Disch, Sevan Habeshian, Rachael Jetson, Puneet Khurana, Andrew Madin, Iacovos N. Michaelides, Ling Peng, Arjan Snijder, Christopher J. Stubbs
المصدر: Bioorganic & Medicinal Chemistry Letters. 75:128948
مصطلحات موضوعية: Small Molecule Libraries, Cell Line, Tumor, Organic Chemistry, Clinical Biochemistry, Drug Discovery, Pharmaceutical Science, Molecular Medicine, Antineoplastic Agents, DNA, Proto-Oncogene Proteins c-met, Protein Kinase Inhibitors, Molecular Biology, Biochemistry
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2
المؤلفون: Ross Overman, Juli Warwicker, Kristin Goldberg, Alexander Pflug, Jeremy S. Disch, Allison Olszewski, Philip B. Rawlins, John P. Guilinger, William McCoull, Rachael Jetson, Anthony D. Keefe, Simon A. Woodcock, Emma Rivers, Olga Collingwood, Elizabeth Hardaker, Sana Bazzaz, Elizabeth Underwood, Marianne Schimpl, J. Willem M. Nissink, Lindsay McMurray, Carolyn Blackett, Diana Gikunju, Jon Winter-Holt, Edward J. Hennessy, Paul D. Smith, Marian Preston, Caroline Truman, Matthew A. Clark, Ying Zhang
المصدر: Journal of medicinal chemistry. 64(6)
مصطلحات موضوعية: Models, Molecular, Computational biology, Crystallography, X-Ray, 01 natural sciences, Chemical library, 03 medical and health sciences, chemistry.chemical_compound, Drug Discovery, Animals, Data Mining, Humans, Immune homeostasis, Protein Kinase Inhibitors, 030304 developmental biology, 0303 health sciences, Tumor microenvironment, c-Mer Tyrosine Kinase, Chemistry, Kinase, Kinase Family, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, Molecular Medicine, Kinase binding, Function (biology), TYRO3
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3
المؤلفون: Xia Tian, Patrick Riley, Diana Gikunju, Ying Zhang, Christopher D. Hupp, Ling Xue, Matthew A. Clark, Betty Chan, Steven Kearnes, Christelle Huguet, Anthony D. Keefe, Dennis Joseph Moccia, John P. Guilinger, Marie-Aude Guié, Christopher James Mulhern, Kevin McCloskey, John W. Cuozzo, Sana Bazzaz, Eric A. Sigel
المصدر: Journal of medicinal chemistry. 63(16)
مصطلحات موضوعية: FOS: Computer and information sciences, Computer Science - Machine Learning, Machine learning, computer.software_genre, Ligands, 01 natural sciences, Quantitative Biology - Quantitative Methods, Machine Learning (cs.LG), Small Molecule Libraries, 03 medical and health sciences, chemistry.chemical_compound, Drug Discovery, Protein Kinase Inhibitors, Selection (genetic algorithm), Quantitative Methods (q-bio.QM), 030304 developmental biology, Epoxide Hydrolases, 0303 health sciences, Artificial neural network, business.industry, Estrogen Receptor alpha, DNA, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, Proto-Oncogene Proteins c-kit, chemistry, FOS: Biological sciences, Hit rate, Molecular Medicine, Artificial intelligence, A kinase, Neural Networks, Computer, business, computer