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1دورية أكاديمية
المؤلفون: Wei-Hua Lee, Hitoshi Higuchi, Sakae Ikeda, Erica L Macke, Tetsuya Takimoto, Bikash R Pattnaik, Che Liu, Li-Fang Chu, Sandra M Siepka, Kathleen J Krentz, C Dustin Rubinstein, Robert F Kalejta, James A Thomson, Robert F Mullins, Joseph S Takahashi, Lawrence H Pinto, Akihiro Ikeda
المصدر: eLife, Vol 5 (2016)
مصطلحات موضوعية: aging, age-dependent retinal diseases, mitochondrial dynamics, retinal pigment epithelium, retina, ENU, Medicine, Science, Biology (General), QH301-705.5
وصف الملف: electronic resource
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2Tissue-specific FAH deficiency alters sleep-wake patterns and results in chronic tyrosinemia in mice
المؤلفون: Kimberly H. Cox, Shuzhang Yang, Jun Chen, Benjamin Tu, Yogarany Chelliah, Marleen H.M. de Groot, Joseph S. Takahashi, Vivek Kumar, Sandra M. Siepka
المصدر: Proceedings of the National Academy of Sciences of the United States of America. 116(44)
مصطلحات موضوعية: 0301 basic medicine, Male, medicine.medical_specialty, Hydrolases, Mutant, Biology, Kidney, 4-Hydroxyphenylpyruvate Dioxygenase, Tyrosinemia, 03 medical and health sciences, chemistry.chemical_compound, Mice, 0302 clinical medicine, Mutant protein, Internal medicine, Enzyme Stability, medicine, Animals, Humans, Enzyme Inhibitors, Gene, Cells, Cultured, chemistry.chemical_classification, Multidisciplinary, Methionine, Cyclohexanones, Tyrosinemias, Point mutation, Homozygote, Biological Sciences, medicine.disease, Circadian Rhythm, Mice, Inbred C57BL, 030104 developmental biology, Endocrinology, Enzyme, HEK293 Cells, chemistry, Liver, Organ Specificity, 030220 oncology & carcinogenesis, Nitrobenzoates, Mutation, Fumarylacetoacetate hydrolase, Suprachiasmatic Nucleus, Sleep
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f23215a061150519b282cc590d6c219
https://pubmed.ncbi.nlm.nih.gov/31611405 -
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المؤلفون: Che Liu, Bikash R. Pattnaik, Robert F. Mullins, Wei-Hua Lee, C. Dustin Rubinstein, James A. Thomson, Li-Fang Chu, Sandra M. Siepka, Tetsuya Takimoto, Akihiro Ikeda, Lawrence H. Pinto, Kathleen J. Krentz, Robert F. Kalejta, Hitoshi Higuchi, Sakae Ikeda, Erica L. Macke, Joseph S. Takahashi
المصدر: eLife, Vol 5 (2016)
eLifeمصطلحات موضوعية: 0301 basic medicine, retina, Mouse, genetic structures, Cell, Mutant, retinal pigment epithelium, Mitochondrion, medicine.disease_cause, Mice, 0302 clinical medicine, Biology (General), Mutation, General Neuroscience, Nuclear Proteins, General Medicine, Anatomy, Mitochondria, 3. Good health, medicine.anatomical_structure, Medicine, age-dependent retinal diseases, Research Article, QH301-705.5, Science, ENU, Biology, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Retinal Diseases, medicine, Animals, Adaptor Proteins, Signal Transducing, Retina, Retinal pigment epithelium, General Immunology and Microbiology, Mechanism (biology), aging, Cell Biology, Macular degeneration, medicine.disease, eye diseases, mitochondrial dynamics, 030104 developmental biology, Mutant Proteins, sense organs, Neuroscience, 030217 neurology & neurosurgery
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9c3f0d5361089b1ffd513e8cfa3ce60
https://elifesciences.org/articles/19264 -
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المؤلفون: Joseph S. Takahashi, Bikash R. Pattnaik, Li-Fang Chu, Erica L. Macke, Lawrence H. Pinto, C. Dustin Rubinstein, Akihiro Ikeda, James A. Thomson, Kathleen J. Krentz, Sakae Ikeda, Tetsuya Takimoto, Robert F. Kalejta, Che Liu, Robert F. Mullins, Hitoshi Higuchi, Wei-Hua Lee, Sandra M. Siepka
مصطلحات موضوعية: chemistry.chemical_compound, chemistry, Mechanism (biology), Dynamics (mechanics), Mutation (genetic algorithm), Age dependent, Retinal, Biology, Cell biology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::1333ee5b464f505917b465cd1a406bab
https://doi.org/10.7554/elife.19264.020 -
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المؤلفون: Jennifer A. Mohawk, Zheng Chen, Zhijian J. Chen, Carla B. Green, Justin Nussbaum, Xinran Liu, Nobuya Koike, Hee Kyung Hong, Joseph S. Takahashi, Vivek Kumar, Ming Xu, Izabela Kornblum, Yongli Shan, Sandra M. Siepka, Seong Kwon Huh, Seung Hee Yoo
المصدر: Cell. 152(5):1091-1105
مصطلحات موضوعية: Male, Cytoplasm, endocrine system, Period (gene), Mutant, Circadian clock, CLOCK Proteins, medicine.disease_cause, General Biochemistry, Genetics and Molecular Biology, Article, 03 medical and health sciences, Mice, 0302 clinical medicine, Ubiquitin, medicine, Animals, Circadian rhythm, Crosses, Genetic, 030304 developmental biology, Cell Nucleus, 0303 health sciences, Mutation, Mice, Inbred C3H, biology, Biochemistry, Genetics and Molecular Biology(all), F-Box Proteins, Ubiquitin ligase, Cryptochromes, Mice, Inbred C57BL, Biochemistry, Proteolysis, biology.protein, Female, 030217 neurology & neurosurgery
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المؤلفون: Martha Hotz Vitaterna, Pan Chen, Sandra M. Siepka, Joseph Bass, Akira Kohsaka, Joseph Grimsby, Stella Odili, Yumiko Kobayashi, Hee Kyung Hong, Joseph S. Takahashi, Franz M. Matschinsky, Deborah Fenner, Bogumil Zelent
المصدر: Journal of Biological Chemistry. 286:39560-39572
مصطلحات موضوعية: Blood Glucose, Male, Alkylating Agents, Protein Folding, Mutation, Missense, Enzyme Activators, Biology, Biochemistry, Gene Expression Regulation, Enzymologic, Maturity onset diabetes of the young, Diabetes Mellitus, Experimental, Mice, Diabetes mellitus, Glucokinase, Genotype, otorhinolaryngologic diseases, medicine, Animals, Humans, Missense mutation, Molecular Biology, Gene, Regulation of gene expression, Genetics, Binding Sites, Cell Biology, medicine.disease, Phenotype, Mice, Mutant Strains, Recombinant Proteins, body regions, Metabolism, Amino Acid Substitution, Liver, Organ Specificity, Ethylnitrosourea, Hyperglycemia, sense organs
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e3f98e3f095d248f375ee8a92866417
https://doi.org/10.1074/jbc.m111.269100 -
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المؤلفون: Junghea Park, Weimin Song, Sandra M. Siepka, Yinin Hu, Joseph S. Takahashi, Vivek Kumar, Choogon Lee, Seung Hee Yoo
المصدر: Cell. 129:1011-1023
مصطلحات موضوعية: Male, endocrine system, Transcription, Genetic, Positional cloning, Period (gene), Molecular Sequence Data, Cell Cycle Proteins, Mice, Inbred Strains, Biology, F-box protein, General Biochemistry, Genetics and Molecular Biology, Mice, 03 medical and health sciences, 0302 clinical medicine, Cryptochrome, Biological Clocks, Animals, Humans, Amino Acid Sequence, 030304 developmental biology, Genetics, 0303 health sciences, Flavoproteins, Biochemistry, Genetics and Molecular Biology(all), F-Box Proteins, Nuclear Proteins, Period Circadian Proteins, Forward genetics, Circadian Rhythm, Cryptochromes, PER2, Amino Acid Substitution, Gene Expression Regulation, Mutagenesis, biology.protein, Female, 030217 neurology & neurosurgery, Transcription Factors, PER1
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المؤلفون: Alison Brown, David J. Kwiatkowski, Tim Wiltshire, David R. Beier, Pamela V. Tran, Cheng Li, Jennifer L. Moran, Kate Montgomery, Raju Kucherlapati, Martha Hotz Vitaterna, Andrew D. Bolton, Noelle D. Dwyer, Danielle K. Manning, Sandra M. Siepka, Bryan C. Bjork, Joseph S. Takahashi
المصدر: Genome Research. 16:436-440
مصطلحات موضوعية: Genetics, Genome, Genotype, Positional cloning, Cloning, Organism, Chromosome Mapping, Mice, Inbred Strains, Single-nucleotide polymorphism, Tag SNP, Biology, Polymorphism, Single Nucleotide, Resources, Mice, Inbred C57BL, Mice, Gene mapping, Mutation, Animals, Humans, SNP, Simple sequence length polymorphism, Gene, Genetics (clinical)
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4534dd3fc12935f9108f5ab9bcf01a70
https://doi.org/10.1101/gr.4563306 -
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المؤلفون: Sandra M. Siepka, Joseph S. Takahashi, Janet Rossant, Martha Hotz Vitaterna, George A. Carlson, Wayne N. Frankel, Monica J. Justice, Amander T. Clark, Dan Goldowitz, Luanne L. Peters, Joseph H. Nadeau
المصدر: Genetica. 122:51-64
مصطلحات موضوعية: Male, Mutagenesis (molecular biology technique), Plant Science, Biology, medicine.disease_cause, Genome, Article, Mice, Genetics, medicine, Animals, Mutation, Chromosome Mapping, General Medicine, Balancer chromosome, Phenotype, United States, Human genetics, Forward genetics, Disease Models, Animal, National Institutes of Health (U.S.), Ethylnitrosourea, Insect Science, Female, Animal Science and Zoology, Nervous System Diseases
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المؤلفون: Won Jun Oh, Hee Kyung Hong, Ethan D. Buhr, Sandra M. Siepka, Shin Yamazaki, Kazuhiro Shimomura, Ook Joon Yoo, Seung Hee Yoo, Joseph S. Takahashi, Caroline H. Ko, Phillip L. Lowrey, Michael Menaker
المصدر: Proceedings of the National Academy of Sciences. 101:5339-5346
مصطلحات موضوعية: Male, medicine.medical_specialty, Recombinant Fusion Proteins, Mice, Transgenic, Motor Activity, Biology, Kidney, RAR-related orphan receptor alpha, Cornea, Mice, Culture Techniques, Internal medicine, medicine, Animals, Circadian rhythm, Luciferases, Lung, Multidisciplinary, Nuclear Proteins, Bacterial circadian rhythms, Circadian Rhythm, Cell biology, Mice, Inbred C57BL, PER2, CLOCK, Phenotype, Endocrinology, Liver, Light effects on circadian rhythm, Pituitary Gland, Luminescent Measurements, Commentary, Period Circadian Proteins, Female, Suprachiasmatic Nucleus, PER1
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a875847257a415f003ca54e0c0fa9c93
https://doi.org/10.1073/pnas.0308709101
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