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1دورية أكاديمية
المؤلفون: Sangeetha Iyer, Feba S. Sam, Nina DiPrimio, Graeme Preston, Jan Verheijen, Kausalya Murthy, Zachary Parton, Hillary Tsang, Jessica Lao, Eva Morava, Ethan O. Perlstein
المصدر: Disease Models & Mechanisms, Vol 12, Iss 11 (2019)
مصطلحات موضوعية: phosphomannomutase 2 deficiency, drug repurposing, pmm2-cdg, congenital disorder of glycosylation, aldose reductase inhibitor, epalrestat, Medicine, Pathology, RB1-214
وصف الملف: electronic resource
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2دورية أكاديمية
المؤلفون: Sangeetha Iyer, Joshua D. Mast, Hillary Tsang, Tamy P. Rodriguez, Nina DiPrimio, Madeleine Prangley, Feba S. Sam, Zachary Parton, Ethan O. Perlstein
المصدر: Disease Models & Mechanisms, Vol 12, Iss 11 (2019)
مصطلحات موضوعية: n-glycanase 1 deficiency, ngly1, skn-1, pngl, congenital disorder of deglycosylation, disease model, aripiprazole, Medicine, Pathology, RB1-214
وصف الملف: electronic resource
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المؤلفون: Andrea Hadjikyriacou, Sangeetha Iyer, Joshua D. Mast, Nina DiPrimio, John Concannon, Joshua Ketterman, Frederic Sigoillot, Tamy P. Rodriguez, Feba S. Sam, Hillary Tsang, Madeleine Prangley, Julide Bilen, Kausalya Murthy, Tom A. Hartl, Christophe Antczak, Jeremy L Jenkins, Nathan T. Ross, Beat Nyfeler, Rishi K. Jain, John A. Tallarico, Ethan O. Perlstein, Stephen M. Canham
مصطلحات موضوعية: Drug discovery, ved/biology, Phenotypic screening, ved/biology.organism_classification_rank.species, Computational biology, Biology, medicine.disease, biology.organism_classification, Phenotype, medicine, Lysosomal storage disease, Mucolipidosis type IV, Drosophila melanogaster, Model organism, Function (biology)
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::96724114f0536d920b8fc593b93f63bf
https://doi.org/10.1101/2021.03.05.434120 -
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المؤلفون: Ethan O. Perlstein, Nina DiPrimio, Hillary Tsang, Sangeetha Iyer, Madeleine Prangley, Zachary Parton, Tamy Portillo Rodriguez, Joshua D. Mast, Feba S. Sam
المصدر: Disease Models & Mechanisms, Vol 12, Iss 11 (2019)
مصطلحات موضوعية: 0301 basic medicine, congenital disorder of deglycosylation, ved/biology.organism_classification_rank.species, Neuroscience (miscellaneous), Medicine (miscellaneous), lcsh:Medicine, Biology, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, 0302 clinical medicine, aripiprazole, Immunology and Microbiology (miscellaneous), medicine, Transcriptional regulation, lcsh:Pathology, NRF1, Model organism, Receptor, Bortezomib, ved/biology, skn-1, disease model, lcsh:R, n-glycanase 1 deficiency, pngl, Phenotype, ngly1, Cell biology, 030104 developmental biology, Dopamine receptor, Proteasome inhibitor, 030217 neurology & neurosurgery, medicine.drug, lcsh:RB1-214
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المؤلفون: Jessica Z. Chan, Jonathan T. Pierce, Pooneh Memar Ardestani, Luisa L. Scott, Stephen F. Martin, Bitna Yi, Sangeetha Iyer, Ashley Crisp, Gabriella Zuniga, Andrew K. Evans, James J. Sahn, Mehrdad Shamloo
المصدر: Journal of Neurochemistry. 140:561-575
مصطلحات موضوعية: Male, 0301 basic medicine, Genetically modified mouse, Amyloid, Sigma-2 receptor, Mice, Transgenic, Biology, Ligands, Biochemistry, Neuroprotection, Article, Mice, 03 medical and health sciences, Cellular and Molecular Neuroscience, Alzheimer Disease, Cell Line, Tumor, Progesterone receptor, medicine, Animals, Humans, Receptors, sigma, PGRMC1, Neuroinflammation, Inflammation, Dose-Response Relationship, Drug, Neurodegeneration, medicine.disease, Mice, Inbred C57BL, Disease Models, Animal, Neuroprotective Agents, 030104 developmental biology, Inflammation Mediators, Cognition Disorders, Neuroscience, Protein Binding
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المؤلفون: Sangeetha, Iyer, Joshua D, Mast, Hillary, Tsang, Tamy P, Rodriguez, Nina, DiPrimio, Madeleine, Prangley, Feba S, Sam, Zachary, Parton, Ethan O, Perlstein
المصدر: Disease Models & Mechanisms
مصطلحات موضوعية: Nematoda, NF-E2-Related Factor 2, Drug Evaluation, Preclinical, Aripiprazole, Congenital disorder of deglycosylation, Bortezomib, Catecholamines, Congenital Disorders of Glycosylation, SKN-1, N-glycanase 1 deficiency, Drug Discovery, Animals, Humans, Peptide-N4-(N-acetyl-beta-glucosaminyl) Asparagine Amidase, NGLY1, Inflammation, Kelch-Like ECH-Associated Protein 1, Disease model, Diptera, Dros, Dd, Disease Models, Animal, Pngl, Signal Transduction, Research Article
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المؤلفون: Joshua D. Mast, Feba S. Sam, Sangeetha Iyer, Madeleine Prangley, Nina DiPrimio, Zachary Parton, Ethan O. Perlstein, Tamy Portillo Rodriguez, Hillary Tsang
مصطلحات موضوعية: Bortezomib, ved/biology, ved/biology.organism_classification_rank.species, Biology, Pharmacology, Phenotype, Drug repositioning, medicine, Proteasome inhibitor, Transcriptional regulation, NRF1, Model organism, Receptor, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a16f9405c762d4bc117663285ecbcbe5
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المؤلفون: Jonathan T. Pierce, S. John Mihic, Luisa L. Scott, Melva Avalos, Sangeetha Iyer, Ashley E. Philpo, Ted Shi, Natalie S. Wu, Thanh-Tu Nguyen, Richard W. Aldrich, Brooke A. Prakash
مصطلحات موضوعية: 0301 basic medicine, BK channel, Xenopus, Cell Line, 03 medical and health sciences, 0302 clinical medicine, Neuropharmacology, In vivo, Animals, Humans, Large-Conductance Calcium-Activated Potassium Channels, Caenorhabditis elegans, Pharmacology, Neurons, biology, Ethanol, Chemistry, HEK 293 cells, biology.organism_classification, Potassium channel, Cell biology, Electrophysiology, Alcoholism, 030104 developmental biology, HEK293 Cells, biology.protein, Molecular Medicine, Peptides, 030217 neurology & neurosurgery, Function (biology)
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa76c37be230122aafeca3f1e42eb560
https://europepmc.org/articles/PMC6178125/ -
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المؤلفون: Jonathan T. Pierce, Evan Hegarty, Sudip Mondal, Wisath Sae-Lee, James J. Sahn, Chris Martin, Timothy R. Hodges, Praveen Satarasinghe, Sangeetha Iyer, Stephen F. Martin, Sertan Kutal Gokce, Luisa L. Scott, Adela Ben-Yakar, Navid Ghorashian
المصدر: ACS chemical neuroscience. 9(5)
مصطلحات موضوعية: 0301 basic medicine, Physiology, Cognitive Neuroscience, Phenotypic screening, High-throughput screening, Microfluidics, Sigma-2 receptor, Computational biology, Ligands, Biochemistry, Neuroprotection, Article, 03 medical and health sciences, Amyloid beta-Protein Precursor, Structure-Activity Relationship, 0302 clinical medicine, Amyloid precursor protein, medicine, Animals, Caenorhabditis elegans, Neurons, biology, Chemistry, Neurodegeneration, Age Factors, Central Nervous System Depressants, Neurodegenerative Diseases, Cell Biology, General Medicine, medicine.disease, Transmembrane protein, Disease Models, Animal, 030104 developmental biology, High-content screening, biology.protein, 030217 neurology & neurosurgery
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المؤلفون: Jonathan T. Pierce, S. J. Mihic, Ashley E. Philpo, Elliott J. Brecht, Luisa L. Scott, Sangeetha Iyer, N. S. Wu, Richard W. Aldrich, Joseph P. Walton
المصدر: Scientific Reports
مصطلحات موضوعية: 0301 basic medicine, Inferior colliculus, BK channel, Peptide, Article, Cell Line, Mice, 03 medical and health sciences, 0302 clinical medicine, Mesencephalon, In vivo, Potassium Channel Blockers, Animals, Humans, Amino Acid Sequence, Large-Conductance Calcium-Activated Potassium Channels, Peptide sequence, Caenorhabditis elegans, chemistry.chemical_classification, Multidisciplinary, biology, Chemistry, Anatomy, biology.organism_classification, Inferior Colliculi, In vitro, Cell biology, 030104 developmental biology, Cell culture, Evoked Potentials, Auditory, biology.protein, Peptides, Ion Channel Gating, 030217 neurology & neurosurgery, Brain Stem