المؤلفون: Tanaka T; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Bunkyo, Tokyo 113-0033, Japan., Hososhima S; Department of Life Science and Applied Chemistry, Graduate School of Engineering, Nagoya Institute of Technology, Nagoya, Aichi 466-8555, Japan., Yamashita Y; Department of Life Science and Applied Chemistry, Graduate School of Engineering, Nagoya Institute of Technology, Nagoya, Aichi 466-8555, Japan., Sugimoto T; Department of Life Science and Applied Chemistry, Graduate School of Engineering, Nagoya Institute of Technology, Nagoya, Aichi 466-8555, Japan., Nakamura T; Department of Life Science and Applied Chemistry, Graduate School of Engineering, Nagoya Institute of Technology, Nagoya, Aichi 466-8555, Japan., Shigemura S; Department of Life Science and Applied Chemistry, Graduate School of Engineering, Nagoya Institute of Technology, Nagoya, Aichi 466-8555, Japan., Iida W; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Bunkyo, Tokyo 113-0033, Japan., Sano FK; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Bunkyo, Tokyo 113-0033, Japan., Oda K; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Bunkyo, Tokyo 113-0033, Japan., Uchihashi T; Department of Physics, Graduate School of Science, Nagoya University, Nagoya, Aichi 464-8602, Japan; Exploratory Research Center on Life and Living Systems, National Institutes of Natural Sciences, Okazaki, Aichi 444-8787, Japan; Institute for Glyco-core Research, Nagoya University, Nagoya, Aichi 464-0814, Japan., Katayama K; Department of Life Science and Applied Chemistry, Graduate School of Engineering, Nagoya Institute of Technology, Nagoya, Aichi 466-8555, Japan; OptoBioTechnology Research Center, Nagoya Institute of Technology, Nagoya, Aichi 466-8555, Japan., Furutani Y; Department of Life Science and Applied Chemistry, Graduate School of Engineering, Nagoya Institute of Technology, Nagoya, Aichi 466-8555, Japan; OptoBioTechnology Research Center, Nagoya Institute of Technology, Nagoya, Aichi 466-8555, Japan., Tsunoda SP; Department of Life Science and Applied Chemistry, Graduate School of Engineering, Nagoya Institute of Technology, Nagoya, Aichi 466-8555, Japan; OptoBioTechnology Research Center, Nagoya Institute of Technology, Nagoya, Aichi 466-8555, Japan., Shihoya W; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Bunkyo, Tokyo 113-0033, Japan. Electronic address: wtrshh9@gmail.com., Kandori H; Department of Life Science and Applied Chemistry, Graduate School of Engineering, Nagoya Institute of Technology, Nagoya, Aichi 466-8555, Japan; OptoBioTechnology Research Center, Nagoya Institute of Technology, Nagoya, Aichi 466-8555, Japan. Electronic address: kandori@nitech.ac.jp., Nureki O; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Bunkyo, Tokyo 113-0033, Japan. Electronic address: nureki@bs.s.u-tokyo.ac.jp.

المصدر: Molecular cell [Mol Cell] 2024 Sep 19; Vol. 84 (18), pp. 3530-3544.e6. Date of Electronic Publication: 2024 Sep 03.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 9802571 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4164 (Electronic) Linking ISSN: 10972765 NLM ISO Abbreviation: Mol Cell Subsets: MEDLINE

مواضيع طبية MeSH: Bacteriorhodopsins*/metabolism , Bacteriorhodopsins*/genetics , Bacteriorhodopsins*/chemistry , Neurons*/metabolism , Neurons*/radiation effects , Optogenetics*/methods, Animals ; Humans ; Action Potentials ; Channelrhodopsins/genetics ; Channelrhodopsins/metabolism ; Channelrhodopsins/chemistry ; Cryptophyta/genetics ; Cryptophyta/metabolism ; HEK293 Cells ; Ion Channel Gating/radiation effects ; Light ; Mutation ; Structure-Activity Relationship

المؤلفون: Kobayashi TA; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Tokyo, Japan., Shimada H; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Tokyo, Japan.; Research Division, Chugai Pharmaceutical Co., Ltd., Kanagawa, Japan., Sano FK; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Tokyo, Japan., Itoh Y; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Tokyo, Japan., Enoki S; Department of Physics, and Universal Biology Institute (UBI), Graduate School of Science, The University of Tokyo, Tokyo, Japan., Okada Y; Department of Physics, and Universal Biology Institute (UBI), Graduate School of Science, The University of Tokyo, Tokyo, Japan.; Department of Cell Biology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.; Laboratory for Cell Polarity Regulation, RIKEN Center for Biosystems Dynamics Research (BDR), Osaka, Japan.; International Research Center for Neurointelligence (WPI-IRCN), The University of Tokyo, Tokyo, Japan., Kusakizako T; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Tokyo, Japan. kusakizako@bs.s.u-tokyo.ac.jp., Nureki O; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Tokyo, Japan. nureki@bs.s.u-tokyo.ac.jp.

المصدر: Nature communications [Nat Commun] 2024 Jul 02; Vol. 15 (1), pp. 5569. Date of Electronic Publication: 2024 Jul 02.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Sodium-Coupled Vitamin C Transporters*/metabolism , Sodium-Coupled Vitamin C Transporters*/chemistry , Sodium-Coupled Vitamin C Transporters*/genetics , Ascorbic Acid*/metabolism , Ascorbic Acid*/chemistry , Cryoelectron Microscopy*, Humans ; Biological Transport ; Sodium/metabolism ; Models, Molecular ; Protein Multimerization ; Protein Binding ; HEK293 Cells ; Protein Conformation

المؤلفون: Shihoya W; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-Ku, Tokyo 113-0033, Japan., Iwama A; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-Ku, Tokyo 113-0033, Japan., Sano FK; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-Ku, Tokyo 113-0033, Japan., Nureki O; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-Ku, Tokyo 113-0033, Japan.

المصدر: Journal of biochemistry [J Biochem] 2024 Jul 01; Vol. 176 (1), pp. 1-10.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Oxford University Press Country of Publication: England NLM ID: 0376600 Publication Model: Print Cited Medium: Internet ISSN: 1756-2651 (Electronic) Linking ISSN: 0021924X NLM ISO Abbreviation: J Biochem Subsets: MEDLINE

مواضيع طبية MeSH: Cryoelectron Microscopy*/methods , Receptors, G-Protein-Coupled*/metabolism , Receptors, G-Protein-Coupled*/chemistry, Humans ; Protein Conformation ; Animals ; Single-Domain Antibodies/chemistry ; Single-Domain Antibodies/metabolism ; Single-Domain Antibodies/immunology ; Models, Molecular

المؤلفون: Iwama A; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Bunkyo, Tokyo, 113-0033, Japan., Kise R; Graduate School of Pharmaceutical Sciences, Tohoku University, 6-3, Aoba, Aramaki, Aoba-ku, Sendai, Miyagi, 980-8578, Japan., Akasaka H; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Bunkyo, Tokyo, 113-0033, Japan., Sano FK; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Bunkyo, Tokyo, 113-0033, Japan., Oshima HS; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Bunkyo, Tokyo, 113-0033, Japan., Inoue A; Graduate School of Pharmaceutical Sciences, Tohoku University, 6-3, Aoba, Aramaki, Aoba-ku, Sendai, Miyagi, 980-8578, Japan. iaska@tohoku.ac.jp.; Graduate School of Pharmaceutical Sciences, Kyoto University, 46-29 Yoshida-Shimo-Adachi-cho, Sakyo-ku, Kyoto, 606-8501, Japan. iaska@tohoku.ac.jp., Shihoya W; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Bunkyo, Tokyo, 113-0033, Japan. wtrshh9@gmail.com., Nureki O; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Bunkyo, Tokyo, 113-0033, Japan. nureki@bs.s.u-tokyo.ac.jp.

المصدر: Nature communications [Nat Commun] 2024 Jun 19; Vol. 15 (1), pp. 4769. Date of Electronic Publication: 2024 Jun 19.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Receptors, G-Protein-Coupled*/metabolism , Receptors, G-Protein-Coupled*/chemistry , Cryoelectron Microscopy*, Humans ; HEK293 Cells ; Protein Binding ; Ligands ; Intercellular Signaling Peptides and Proteins

المؤلفون: Izume T; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Bunkyo-ku, Tokyo, 113-0033, Japan., Kawahara R; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Bunkyo-ku, Tokyo, 113-0033, Japan., Uwamizu A; Department of Health Chemistry, Graduate School of Pharmaceutical Sciences, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan., Chen L; Department of Organic and Medicinal Chemistry, Graduate School of Pharmaceutical Sciences, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan., Yaginuma S; Department of Health Chemistry, Graduate School of Pharmaceutical Sciences, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan., Omi J; Department of Health Chemistry, Graduate School of Pharmaceutical Sciences, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan., Kawana H; Department of Health Chemistry, Graduate School of Pharmaceutical Sciences, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan., Hou F; Department of Health Chemistry, Graduate School of Pharmaceutical Sciences, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan., Sano FK; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Bunkyo-ku, Tokyo, 113-0033, Japan., Tanaka T; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Bunkyo-ku, Tokyo, 113-0033, Japan., Kobayashi K; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Bunkyo-ku, Tokyo, 113-0033, Japan., Okamoto HH; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Bunkyo-ku, Tokyo, 113-0033, Japan., Kise Y; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Bunkyo-ku, Tokyo, 113-0033, Japan., Ohwada T; Department of Organic and Medicinal Chemistry, Graduate School of Pharmaceutical Sciences, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan. ohwada@mol.f.u-tokyo.ac.jp., Aoki J; Department of Health Chemistry, Graduate School of Pharmaceutical Sciences, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan. jaok@mol.f.u-tokyo.ac.jp., Shihoya W; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Bunkyo-ku, Tokyo, 113-0033, Japan. wtrshh9@gmail.com., Nureki O; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Bunkyo-ku, Tokyo, 113-0033, Japan. nureki@bs.s.u-tokyo.ac.jp.

المصدر: Nature communications [Nat Commun] 2024 Feb 07; Vol. 15 (1), pp. 902. Date of Electronic Publication: 2024 Feb 07.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Fatty Acids*/metabolism , Lysophospholipids*/metabolism, Humans ; Cryoelectron Microscopy ; Ligands ; Receptors, Lysophospholipid/agonists ; Receptors, Lysophospholipid/metabolism

المؤلفون: Oshima HS; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan., Sano FK; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan., Akasaka H; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan., Iwama A; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan., Shihoya W; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan. Electronic address: wtrshh9@gmail.com., Nureki O; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan. Electronic address: nureki@bs.s.u-tokyo.ac.jp.

المصدر: Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2024 Jan 22; Vol. 693, pp. 149361. Date of Electronic Publication: 2023 Dec 07.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 0372516 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2104 (Electronic) Linking ISSN: 0006291X NLM ISO Abbreviation: Biochem Biophys Res Commun Subsets: MEDLINE

مواضيع طبية MeSH: GTP-Binding Proteins*/metabolism , Rhodopsin*/metabolism, Cryoelectron Microscopy ; Antibodies/metabolism

المؤلفون: Maharana J; Department of Biological Sciences, Indian Institute of Technology Kanpur, Kanpur, India., Sano FK; Graduate School of Science, The University of Tokyo, Tokyo, Japan., Sarma P; Department of Biological Sciences, Indian Institute of Technology Kanpur, Kanpur, India., Yadav MK; Department of Biological Sciences, Indian Institute of Technology Kanpur, Kanpur, India., Duan L; School of Pharmacy, Sungkyunkwan University, Suwon, Republic of Korea., Stepniewski TM; Research Program on Biomedical Informatics, Hospital del Mar Research Institute and Pompeu Fabra University, Barcelona, Spain., Chaturvedi M; Department of Biological Sciences, Indian Institute of Technology Kanpur, Kanpur, India., Ranjan A; Department of Biological Sciences, Indian Institute of Technology Kanpur, Kanpur, India., Singh V; Department of Biological Sciences, Indian Institute of Technology Kanpur, Kanpur, India., Saha S; Department of Biological Sciences, Indian Institute of Technology Kanpur, Kanpur, India., Mahajan G; Department of Biological Sciences, Indian Institute of Technology Kanpur, Kanpur, India., Chami M; BioEM Lab, Biozentrum, University of Basel, Basel, Switzerland., Shihoya W; Graduate School of Science, The University of Tokyo, Tokyo, Japan., Selent J; Research Program on Biomedical Informatics, Hospital del Mar Research Institute and Pompeu Fabra University, Barcelona, Spain., Chung KY; School of Pharmacy, Sungkyunkwan University, Suwon, Republic of Korea., Banerjee R; Department of Biological Sciences, Indian Institute of Technology Kanpur, Kanpur, India., Nureki O; Graduate School of Science, The University of Tokyo, Tokyo, Japan., Shukla AK; Department of Biological Sciences, Indian Institute of Technology Kanpur, Kanpur, India.

المصدر: Science (New York, N.Y.) [Science] 2024 Jan 05; Vol. 383 (6678), pp. 101-108. Date of Electronic Publication: 2024 Jan 04.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-9203 (Electronic) Linking ISSN: 00368075 NLM ISO Abbreviation: Science Subsets: MEDLINE

مواضيع طبية MeSH: beta-Arrestins*/chemistry , Receptors, G-Protein-Coupled*/chemistry , Protein Interaction Domains and Motifs*, Cryoelectron Microscopy ; Signal Transduction ; Protein Conformation, beta-Strand ; Protein Conformation, alpha-Helical ; Humans

المؤلفون: Shihoya W; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-Ku, Tokyo 113-0033, Japan., Sano FK; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-Ku, Tokyo 113-0033, Japan., Nureki O; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, 7-3-1 Hongo, Bunkyo-Ku, Tokyo 113-0033, Japan.

المصدر: Journal of biochemistry [J Biochem] 2023 Sep 29; Vol. 174 (4), pp. 317-325.

نوع المنشور: Review; Journal Article

بيانات الدورية: Publisher: Oxford University Press Country of Publication: England NLM ID: 0376600 Publication Model: Print Cited Medium: Internet ISSN: 1756-2651 (Electronic) Linking ISSN: 0021924X NLM ISO Abbreviation: J Biochem Subsets: MEDLINE

مواضيع طبية MeSH: Drug Inverse Agonism* , Endothelins*/metabolism, Cryoelectron Microscopy ; Receptors, Endothelin/chemistry ; Receptors, Endothelin/metabolism ; Signal Transduction

المؤلفون: Sano FK; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Tokyo, Japan., Akasaka H; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Tokyo, Japan., Shihoya W; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Tokyo, Japan., Nureki O; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Tokyo, Japan.

المصدر: ELife [Elife] 2023 Apr 25; Vol. 12. Date of Electronic Publication: 2023 Apr 25.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: eLife Sciences Publications, Ltd Country of Publication: England NLM ID: 101579614 Publication Model: Electronic Cited Medium: Internet ISSN: 2050-084X (Electronic) Linking ISSN: 2050084X NLM ISO Abbreviation: Elife Subsets: MEDLINE

مواضيع طبية MeSH: Endothelin-1*/metabolism , Endothelins*/metabolism, Cryoelectron Microscopy ; Receptor, Endothelin B/metabolism ; GTP-Binding Proteins/metabolism

المؤلفون: Nakagawa R; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Tokyo, Japan., Hirano H; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Tokyo, Japan., Omura SN; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Tokyo, Japan., Nety S; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; McGovern Institute for Brain Research at MIT, Massachusetts Institute of Technology, Cambridge, MA, USA.; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.; Department of Brain and Cognitive Science, Massachusetts Institute of Technology, Cambridge, MA, USA.; Howard Hughes Medical Institute, Cambridge, MA, USA., Kannan S; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; McGovern Institute for Brain Research at MIT, Massachusetts Institute of Technology, Cambridge, MA, USA.; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.; Department of Brain and Cognitive Science, Massachusetts Institute of Technology, Cambridge, MA, USA.; Howard Hughes Medical Institute, Cambridge, MA, USA., Altae-Tran H; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; McGovern Institute for Brain Research at MIT, Massachusetts Institute of Technology, Cambridge, MA, USA.; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.; Department of Brain and Cognitive Science, Massachusetts Institute of Technology, Cambridge, MA, USA.; Howard Hughes Medical Institute, Cambridge, MA, USA., Yao X; Department of Chemistry and Biotechnology, Graduate School of Engineering, The University of Tokyo, Tokyo, Japan., Sakaguchi Y; Department of Chemistry and Biotechnology, Graduate School of Engineering, The University of Tokyo, Tokyo, Japan., Ohira T; Department of Chemistry and Biotechnology, Graduate School of Engineering, The University of Tokyo, Tokyo, Japan., Wu WY; Laboratory of Microbiology, Wageningen University and Research, Wageningen, The Netherlands., Nakayama H; Biomolecular Characterization Unit, RIKEN Center for Sustainable Resource Science, Saitama, Japan., Shuto Y; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Tokyo, Japan., Tanaka T; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Tokyo, Japan., Sano FK; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Tokyo, Japan., Kusakizako T; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Tokyo, Japan., Kise Y; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Tokyo, Japan.; Curreio, The University of Tokyo, Tokyo, Japan., Itoh Y; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Tokyo, Japan., Dohmae N; Biomolecular Characterization Unit, RIKEN Center for Sustainable Resource Science, Saitama, Japan., van der Oost J; Laboratory of Microbiology, Wageningen University and Research, Wageningen, The Netherlands., Suzuki T; Department of Chemistry and Biotechnology, Graduate School of Engineering, The University of Tokyo, Tokyo, Japan., Zhang F; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; McGovern Institute for Brain Research at MIT, Massachusetts Institute of Technology, Cambridge, MA, USA.; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.; Department of Brain and Cognitive Science, Massachusetts Institute of Technology, Cambridge, MA, USA.; Howard Hughes Medical Institute, Cambridge, MA, USA., Nureki O; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Tokyo, Japan. nureki@bs.s.u-tokyo.ac.jp.; Curreio, The University of Tokyo, Tokyo, Japan. nureki@bs.s.u-tokyo.ac.jp.

المصدر: Nature [Nature] 2023 Apr; Vol. 616 (7956), pp. 390-397. Date of Electronic Publication: 2023 Apr 05.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE

مواضيع طبية MeSH: Bacterial Proteins*/chemistry , Bacterial Proteins*/metabolism , Bacterial Proteins*/ultrastructure , Cryoelectron Microscopy* , DNA Transposable Elements*/genetics , Endodeoxyribonucleases*/chemistry , Endodeoxyribonucleases*/metabolism , Endodeoxyribonucleases*/ultrastructure , Deinococcus*/enzymology , Deinococcus*/genetics, CRISPR-Associated Proteins/chemistry ; CRISPR-Associated Proteins/metabolism ; CRISPR-Cas Systems ; DNA/chemistry ; DNA/genetics ; DNA/metabolism ; DNA/ultrastructure ; RNA, Guide, CRISPR-Cas Systems/chemistry ; RNA, Guide, CRISPR-Cas Systems/genetics ; RNA, Guide, CRISPR-Cas Systems/metabolism ; RNA, Guide, CRISPR-Cas Systems/ultrastructure ; Substrate Specificity