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1دورية أكاديمية
المؤلفون: Aimée Bastidas-Ponce, Sara S. Roscioni, Ingo Burtscher, Erik Bader, Michael Sterr, Mostafa Bakhti, Heiko Lickert
المصدر: Molecular Metabolism, Vol 6, Iss 6, Pp 524-534 (2017)
مصطلحات موضوعية: Internal medicine, RC31-1245
وصف الملف: electronic resource
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المؤلفون: Aparna Neelakandhan, Matthias H. Tschöp, Mostafa Bakhti, Katrin Fischer, Aimée Bastidas-Ponce, Sophie Tritschler, Miguel A. Sánchez-Garrido, Anika Böttcher, Stephan Sachs, Erik Bader, Susanna M. Hofmann, Sara S. Roscioni, Fabian J. Theis, Siegfried Ussar, Brian Finan, Heiko Lickert, Annette Feuchtinger, Sigrid Jall, Burcak Yesildag, Richard D. DiMarchi, Marta Tarquis-Medina, Alexandra Harger, Maximilian Kleinert, Marion Cornu, Christine B. Jensen, Bin Yang, Timo D. Müller
المصدر: Nat. Metab. 2, 192-209 (2020)
Sachs, S, Bastidas-Ponce, A, Tritschler, S, Bakhti, M, Böttcher, A, Sánchez-Garrido, M A, Tarquis-Medina, M, Kleinert, M, Fischer, K, Jall, S, Harger, A, Bader, E, Roscioni, S, Ussar, S, Feuchtinger, A, Yesildag, B, Neelakandhan, A, Jensen, C B, Cornu, M, Yang, B, Finan, B, DiMarchi, R D, Tschöp, M H, Theis, F J, Hofmann, S M, Müller, T D & Lickert, H 2020, ' Targeted pharmacological therapy restores β-cell function for diabetes remission ', Nature Metabolism, vol. 2, no. 2, pp. 192-209 . https://doi.org/10.1038/s42255-020-0171-3
Nature Metabolismمصطلحات موضوعية: β cell function, Pharmacological therapy, Polypharmacology, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, 030209 endocrinology & metabolism, Pharmacology, Protein degradation, Streptozocin, Diabetes Mellitus, Experimental, Mice, 03 medical and health sciences, 0302 clinical medicine, Glucagon-Like Peptide 1, Insulin-Secreting Cells, Physiology (medical), Diabetes mellitus, Internal Medicine, Animals, Homeostasis, Humans, Hypoglycemic Agents, Insulin, Medicine, 030304 developmental biology, 0303 health sciences, geography, geography.geographical_feature_category, biology, business.industry, Regeneration (biology), Remission Induction, Estrogens, Cell Biology, medicine.disease, Islet, 3. Good health, Insulin receptor, biology.protein, Cancer research, Experimental pathology, business
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::326ff9bec73d13a151285ddd1708c077
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=58501 -
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المؤلفون: Sara S. Roscioni, Adriana Migliorini, Heiko Lickert
المصدر: Diabetologia. 59:1838-1842
مصطلحات موضوعية: 0301 basic medicine, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, Cell- and Tissue-Based Therapy, Biology, Regenerative medicine, Islets of Langerhans, Mice, 03 medical and health sciences, 0302 clinical medicine, Insulin-Secreting Cells, Cell polarity, Internal Medicine, medicine, Animals, Humans, Beta (finance), Wnt Signaling Pathway, geography, geography.geographical_feature_category, Effector, Insulin, Cell Differentiation, Islet, humanities, Cell biology, 030104 developmental biology, Immunology, Biomarker (medicine), Beta cell, Microtubule-Associated Proteins, 030217 neurology & neurosurgery
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4دورية أكاديمية
المؤلفون: Erik Bader, Adriana Migliorini, Moritz Gegg, Noah Moruzzi, Jantje Gerdes, Sara S. Roscioni, Mostafa Bakhti, Elisabeth Brandl, Martin Irmler, Johannes Beckers, Michaela Aichler, Annette Feuc
المصدر: Nature, Nature. 535(7612):430-434
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المؤلفون: Sigrid Jall, Burcak Yesildag, Sara S. Roscioni, Fabian J. Theis, Christine B. Jensen, Anika Böttcher, Heiko Lickert, Annette Feuchtinger, Aparna Neelakandhan, Richard D. DiMarchi, Marta Tarquis-Medina, Alexandra Harger, Maximilian Kleinert, Erik Bader, Miguel A. Sánchez-Garrido, Brian Finan, Katrin Fischer, Aimée Bastidas-Ponce, Matthias H. Tschöp, Mostafa Bakhti, Siegfried Ussar, Marion Cornu, Sophie Tritschler, Timo D. Müller, Stephan Sachs, Bin Yang, Susanna M. Hofmann
المصدر: Nature Metabolism. 2:380-380
مصطلحات موضوعية: β cell function, Pharmacological therapy, business.industry, Endocrinology, Diabetes and Metabolism, MEDLINE, Cell Biology, Bioinformatics, medicine.disease, Text mining, Physiology (medical), Diabetes mellitus, Internal Medicine, medicine, business
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المؤلفون: Dick de Zeeuw, Sara S. Roscioni, Hiddo J.L. Heerspink
المصدر: Nature Reviews Nephrology. 10:77-87
مصطلحات موضوعية: ANGIOTENSIN-CONVERTING ENZYME, CHRONIC KIDNEY-DISEASE, Angiotensin-Converting Enzyme Inhibitors, Pharmacology, Bioinformatics, GLOMERULAR-FILTRATION-RATE, End stage renal disease, Renin-Angiotensin System, Diabetic nephropathy, Angiotensin Receptor Antagonists, chemistry.chemical_compound, Renin–angiotensin system, Post-hoc analysis, medicine, Humans, Diabetic Nephropathies, BEZOLD-JARISCH REFLEX, TERM ANTIHYPERTENSIVE TREATMENT, Aldosterone, biology, POST-HOC ANALYSIS, business.industry, STAGE RENAL-DISEASE, Angiotensin-converting enzyme, MINERALOCORTICOID-RECEPTOR ANTAGONIST, RANDOMIZED CONTROLLED-TRIAL, medicine.disease, CHRONIC HEART-FAILURE, Blockade, Clinical trial, chemistry, Nephrology, Disease Progression, biology.protein, business
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المصدر: Nature Reviews Nephrology. 8(12):691-699
مصطلحات موضوعية: CHRONIC KIDNEY-DISEASE, medicine.medical_specialty, Hypertension, Renal, Hyperkalemia, TYPE-2 DIABETIC-NEPHROPATHY, medicine.drug_class, Population, BLOOD-PRESSURE, CONVERTING ENZYME-INHIBITOR, ANGIOTENSIN-ALDOSTERONE SYSTEM, chemistry.chemical_compound, DOUBLE-BLIND, Mineralocorticoid receptor, Risk Factors, Internal medicine, Diabetes mellitus, Medicine, Albuminuria, Humans, Intensive care medicine, education, Diuretics, Mineralocorticoid Receptor Antagonists, education.field_of_study, RANDOMIZED ALDACTONE EVALUATION, Aldosterone, CONGESTIVE-HEART-FAILURE, business.industry, medicine.disease, Blood pressure, chemistry, Nephrology, Mineralocorticoid, TRANSTUBULAR POTASSIUM CONCENTRATION, Cardiology, CHRONIC-RENAL-FAILURE, medicine.symptom, business
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المؤلفون: Sara S. Roscioni, Heiko Lickert, Moritz Gegg, Adriana Migliorini
المصدر: Nat. Rev. Endocrinol. 12, 695-709 (2016)
مصطلحات موضوعية: 0301 basic medicine, Endocrinology, Diabetes and Metabolism, Cellular differentiation, Cell Plasticity, Context (language use), Biology, Neogenesis, Transcriptome, Islets of Langerhans, 03 medical and health sciences, Endocrinology, Insulin-Secreting Cells, Animals, Humans, Cell Lineage, Progenitor cell, Stem Cells, Wnt signaling pathway, Cell Polarity, Cell Differentiation, biology.organism_classification, Phenotype, 030104 developmental biology, Immunology, Microtubule-Associated Proteins, Neuroscience
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88668a8d6644d7c43ff5d8bd56c53e1a
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المؤلفون: Sara S. Roscioni, Carolina R.S. Elzinga, Alwin G. Prins, Andrew J. Halayko, Harm Maarsingh, Herman Meurs, Mark H. Menzen, Bart G. J. Dekkers, Martina Schmidt
المصدر: British Journal of Pharmacology. 164:958-969
مصطلحات موضوعية: Pharmacology, medicine.medical_specialty, Platelet-derived growth factor, biology, Cell growth, Calponin, respiratory system, respiratory tract diseases, Cell biology, chemistry.chemical_compound, Endocrinology, chemistry, Internal medicine, Myosin, biology.protein, medicine, medicine.symptom, Protein kinase A, Platelet-derived growth factor receptor, Actin, Muscle contraction
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المؤلفون: Harm Maarsingh, Herman Meurs, Alwin G. Prins, Martina Schmidt, Sara S. Roscioni, Bart G. J. Dekkers, Mark H. Menzen
المصدر: British Journal of Pharmacology. 162:193-209
مصطلحات موضوعية: Pharmacology, MAPK/ERK pathway, medicine.medical_specialty, Platelet-derived growth factor, biology, Activator (genetics), Kinase, Cell biology, Enzyme activator, chemistry.chemical_compound, Endocrinology, chemistry, Internal medicine, medicine, biology.protein, Phosphorylation, Protein kinase A, Platelet-derived growth factor receptor