نتائج البحث - "Sarabindu Roy"

المصدر: Granchi, C, Roy, S, De Simone, A, Salvetti, I, Tuccinardi, T, Martinelli, A, Macchia, M, Lanza, M, Betti, L, Giannaccini, G, Lucacchini, A, Giovannetti, E, Sciarrillo, R, Peters, G J & Minutolo, F 2011, ' N-Hydroxyindole-based inhibitors of lactate dehydrogenase against cancer cell proliferation ', European Journal of Medicinal Chemistry, vol. 46, no. 11, pp. 5398-5407 . https://doi.org/10.1016/j.ejmech.2011.08.046
European Journal of Medicinal Chemistry, 46(11), 5398-5407. Elsevier Masson SAS

مصطلحات موضوعية: Gene isoform, Indoles, Protein Conformation, Carboxylic Acids, Antineoplastic Agents, Oxidative phosphorylation, Molecular Dynamics Simulation, Inhibitory Concentration 50, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Cell Line, Tumor, Lactate dehydrogenase, Drug Discovery, medicine, Humans, Glycolysis, Enzyme kinetics, Enzyme Inhibitors, Cell Proliferation, 030304 developmental biology, Pharmacology, 0303 health sciences, L-Lactate Dehydrogenase, Organic Chemistry, Cancer, General Medicine, medicine.disease, Molecular biology, Warburg effect, 3. Good health, Isoenzymes, chemistry, Biochemistry, Cell culture, 030220 oncology & carcinogenesis, Lactate Dehydrogenase 5

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c2b5eb6a08bbeef78124ade159c9e03
https://doi.org/10.1016/j.ejmech.2011.08.046

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8

Discovery of N-Hydroxyindole-Based Inhibitors of Human Lactate Dehydrogenase Isoform A (LDH-A) as Starvation Agents against Cancer Cells

المؤلفون: Nicola Funel, Elisa Giovannetti, Gino Giannaccini, Leticia G. Leon, Mario Lanza, Adriano Martinelli, Chiara Giacomelli, Marco Macchia, Godefridus J. Peters, Paul J. Hergenrother, Antonio Lucacchini, Filippo Minutolo, Carlotta Granchi, Emilia C. Calvaresi, Sarabindu Roy, Tiziano Tuccinardi, Rahul Palchaudhuri, Laura Betti

المساهمون: Medical oncology laboratory, CCA - Innovative therapy

المصدر: Granchi, C, Roy, S, Giacomelli, C, Macchia, M, Tuccinardi, T, Martinelli, A, Lanza, M, Betti, L, Giannaccini, G, Lucacchini, A, Funel, N, Leon, L G, Giovannetti, E, Peters, G J, Palchaudhuri, R, Calvaresi, E C, Hergenrother, P J & Minutolo, F 2011, ' Discovery of N-Hydroxyindole-Based Inhibitors of Human Lactate Dehydrogenase Isoform A (LDH-A) as Starvation Agents against Cancer Cells ', Journal of Medicinal Chemistry, vol. 54, no. 6, pp. 1599-1612 . https://doi.org/10.1021/jm101007q
Journal of Medicinal Chemistry, 54(6), 1599-1612. American Chemical Society

مصطلحات موضوعية: Models, Molecular, Indoles, Antineoplastic Agents, Oxidative phosphorylation, Substrate Specificity, 03 medical and health sciences, chemistry.chemical_compound, Structure-Activity Relationship, 0302 clinical medicine, Lactate dehydrogenase, Cell Line, Tumor, Drug Discovery, Pyruvic Acid, medicine, Humans, Glycolysis, Lactic Acid, 030304 developmental biology, Cell Proliferation, chemistry.chemical_classification, 0303 health sciences, L-Lactate Dehydrogenase, Cell Cycle, Cancer, medicine.disease, NAD, Warburg effect, Cell Hypoxia, 3. Good health, Isoenzymes, Enzyme, Glucose, chemistry, Biochemistry, Cell culture, 030220 oncology & carcinogenesis, Cancer cell, Molecular Medicine, Drug Screening Assays, Antitumor, Lactate Dehydrogenase 5