المؤلفون: Chantal J.M. van Opbergen, Maartje Noorman, Anna Pfenniger, Jaël S. Copier, Sarah H. Vermij, Zhen Li, Roel van der Nagel, Mingliang Zhang, Jacques M.T. de Bakker, Aaron M. Glass, Peter J. Mohler, Steven M. Taffet, Marc A. Vos, Harold V.M. van Rijen, Mario Delmar, Toon A.B. van Veen

المصدر: International Journal of Molecular Sciences, Vol 20, Iss 17, p 4076 (2019)

مصطلحات موضوعية: arrhythmogenic cardiomyopathy, plakophilin-2, second hit, calcium handling, fibrosis, exercise, cardiac pressure overload, inflammation, Biology (General), QH301-705.5, Chemistry, QD1-999

وصف الملف: electronic resource

Relation: https://www.mdpi.com/1422-0067/20/17/4076; https://doaj.org/toc/1422-0067

URL الوصول: https://doaj.org/article/3524f74346104ca29ffea14b78d8a22e

المؤلفون: Alejandra Leo-Macias, Mingliang Zhang, Marta Pérez-Hernández, Paul W. Burridge, Feng-Xia Liang, Mario Delmar, Sarah Keegan, Joon Chul Kim, David Fenyö, Esperanza Agullo-Pascual, Eli Rothenberg, Mariam Jouni, Sarah H. Vermij

المصدر: Circulation Research. 128:419-432

مصطلحات موضوعية: biology, Physiology, Chemistry, Sodium channel, biology.protein, Biophysics, Mitochondrial homeostasis, Nav1.5, Mitochondrion, Cardiology and Cardiovascular Medicine, Subsarcolemmal mitochondria

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::835a48d70a860f85e6d5a27261415864
https://doi.org/10.1161/circresaha.120.318239

المؤلفون: Geoffrey S. Pitt, Valentin Sottas, Zizun Wang, Daniela Ross-Kaschitza, Sarah H. Vermij, Jean-Sébastien Rougier, Hugues Abriel, Elena Zaklyazminskaya, Anna Shestak, Andy Hudmon

مصطلحات موضوعية: biology, Calmodulin, chemistry, In silico, Sodium channel, Biotinylation, biology.protein, chemistry.chemical_element, Transfection, Nav1.5, Binding site, Calcium, Cell biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::146794d8059b25a503a6f70c98cf4080
https://doi.org/10.1101/2020.06.02.129288

المؤلفون: Jean-Sébastien Rougier, Esperanza Agulló-Pascual, Hugues Abriel, Eli Rothenberg, Sarah H. Vermij, Mario Delmar

المصدر: Circulation. Arrhythmia and Electrophysiology
Vermij, Sarah H.; Rougier, Jean-Sébastien; Agulló-Pascual, Esperanza; Rothenberg, Eli; Delmar, Mario; Abriel, Hugues (2020). Single-Molecule Localization of the Cardiac Voltage-Gated Sodium Channel Reveals Different Modes of Reorganization at Cardiomyocyte Membrane Domains. Circulation. Arrhythmia and electrophysiology, 13(7), pp. 628-639. Lippincott Williams & Wilkins 10.1161/CIRCEP.119.008241 <http://dx.doi.org/10.1161/CIRCEP.119.008241>

مصطلحات موضوعية: Single molecule localization, 610 Medicine & health, cardiomyocyte, Mice, Transgenic, 030204 cardiovascular system & hematology, dystrophin, Membrane Potentials, NAV1.5 Voltage-Gated Sodium Channel, 03 medical and health sciences, 0302 clinical medicine, Physiology (medical), Medicine, Animals, Computer Simulation, Myocytes, Cardiac, 030304 developmental biology, 0303 health sciences, biology, business.industry, Sodium channel, Cell Membrane, Models, Cardiovascular, Original Articles, electrophysiology, Single Molecule Imaging, Electrophysiology, Protein Transport, Membrane, cardiac arrhythmias, membranes, biology.protein, Biophysics, ComputingMethodologies_DOCUMENTANDTEXTPROCESSING, microscopy, Mice, Inbred mdx, 570 Life sciences, Cardiology and Cardiovascular Medicine, business, Dystrophin, Ion Channel Gating, sodium channel

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f183aef6656ea8b824bc7c0acd22a71

المؤلفون: Esperanza Agulló-Pascual, Sarah H. Vermij, Eli Rothenberg, Jean-Sébastien Rougier, Hugues Abriel, Mario Delmar

مصطلحات موضوعية: Single molecule localization, 0303 health sciences, biology, Chemistry, Sodium channel, 030204 cardiovascular system & hematology, Nav1.5, Cell biology, 03 medical and health sciences, 0302 clinical medicine, biology.protein, Dystrophin, Gene, Groove (engineering), Function (biology), 030304 developmental biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a6ad7adb0eac21250249feabda1ec43

المؤلفون: Mingliang Zhang, Chantal J. M. van Opbergen, Maartje Noorman, Harold V.M. van Rijen, Mario Delmar, Sarah H. Vermij, Anna Pfenniger, Jacques M.T. de Bakker, Marc A. Vos, Zhen Li, Roel van der Nagel, Aaron Glass, Jaël S Copier, Steven M. Taffet, Toon A.B. van Veen, Peter J. Mohler

المساهمون: Academic Medical Center

المصدر: International journal of molecular sciences, 20(17). Multidisciplinary Digital Publishing Institute (MDPI)
International Journal of Molecular Sciences, Vol 20, Iss 17, p 4076 (2019)
International Journal of Molecular Sciences
van Opbergen, Chantal J M; Noorman, Maartje; Pfenniger, Anna; Copier, Jaël S; Vermij, Sarah H.; Li, Zhen; van der Nagel, Roel; Zhang, Mingliang; de Bakker, Jacques M T; Glass, Aaron M; Mohler, Peter J; Taffet, Steven M; Vos, Marc A; van Rijen, Harold V M; Delmar, Mario; van Veen, Toon A B (2019). Plakophilin-2 Haploinsufficiency Causes Calcium Handling Deficits and Modulates the Cardiac Response Towards Stress. International journal of molecular sciences, 20(17) Molecular Diversity Preservation International MDPI 10.3390/ijms20174076 <http://dx.doi.org/10.3390/ijms20174076>
Volume 20
Issue 17

مصطلحات موضوعية: 0301 basic medicine, Cardiomyopathy, Haploinsufficiency, 030204 cardiovascular system & hematology, Polymerase Chain Reaction, Nervous System Autoimmune Disease, Experimental, lcsh:Chemistry, Electrocardiography, Mice, 0302 clinical medicine, Fibrosis, 610 Medicine & health, lcsh:QH301-705.5, Spectroscopy, Mice, Knockout, exercise, General Medicine, arrhythmogenic cardiomyopathy, Penetrance, Immunohistochemistry, Pathophysiology, Computer Science Applications, Echocardiography, medicine.symptom, Cardiomyopathies, medicine.medical_specialty, Programmed cell death, Blotting, Western, Inflammation, Catalysis, Article, Inorganic Chemistry, 03 medical and health sciences, Internal medicine, medicine, Journal Article, second hit, Animals, Physical and Theoretical Chemistry, Molecular Biology, Pressure overload, plakophilin-2, business.industry, Organic Chemistry, fibrosis, cardiac pressure overload, medicine.disease, Mice, Inbred C57BL, 030104 developmental biology, Endocrinology, lcsh:Biology (General), lcsh:QD1-999, inflammation, calcium handling, 570 Life sciences, biology, Calcium, business, Plakophilins

وصف الملف: image/pdf; application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::612a305374d1d1c344284cc5084b43b4
https://pure.amc.nl/en/publications/plakophilin2-haploinsufficiency-causes-calcium-handling-deficits-and-modulates-the-cardiac-response-towards-stress(2519daf6-96ab-4286-8e3a-ce0c4826d452).html

المؤلفون: Jan P. Kucera, Hugues Abriel, Sarah H. Vermij

المصدر: Vermij, Sarah Helena; Abriel, Hugues; Kucera, Jan (2019). Modeling Depolarization Delay, Sodium Currents, and Electrical Potentials in Cardiac Transverse Tubules. Frontiers in physiology, 10(1487) Frontiers Research Foundation 10.3389/fphys.2019.01487 <http://dx.doi.org/10.3389/fphys.2019.01487>
Frontiers in Physiology
Frontiers in Physiology, Vol 10 (2019)

مصطلحات موضوعية: lcsh:QP1-981, Chemistry, Ephaptic coupling, Physiology, Sodium channel, transverse tubules, Depolarization, cardiomyocytes, 610 Medicine & health, lcsh:Physiology, Tubule, Membrane, action potential, voltage-gated calcium channels, Physiology (medical), Biophysics, Extracellular, Myocyte, voltage-gated sodium channels, 570 Life sciences, biology, Ion channel, Original Research

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd84d8ee102291043893b3baf8629702

المؤلفون: Irene Keller, Hugues Abriel, Morgan Yoann Edwin Chevalier, Sarah H. Vermij, Ludovic Gillet, Kurt Wyler

المصدر: Scientific Data. 5

مصطلحات موضوعية: 0301 basic medicine, Statistics and Probability, Computational biology, 030204 cardiovascular system & hematology, Biology, Library and Information Sciences, Computer Science Applications, Education, Transcriptome, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, Knockout mouse, CASK, Statistics, Probability and Uncertainty, Information Systems

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4021d43efaa10584db4b38ebf2158d9

المؤلفون: Jan P. Kucera, Sarah H. Vermij, Hugues Abriel

المصدر: Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1867:118502

مصطلحات موضوعية: Sarcomeres, 0301 basic medicine, Materials science, Action potential, Heart Ventricles, Action Potentials, 030204 cardiovascular system & hematology, Sarcomere, Nerve conduction velocity, 03 medical and health sciences, Sarcolemma, 0302 clinical medicine, Cardiac conduction, Humans, Myocyte, Myocytes, Cardiac, Calcium Signaling, Molecular Biology, Ion channel, Sodium channel, Sodium, Cell Biology, Thermal conduction, Sarcoplasmic Reticulum, 030104 developmental biology, Biophysics, Electromagnetic Phenomena

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ef51288de625d6ed7b4fc8426522afd
https://doi.org/10.1016/j.bbamcr.2019.06.016

المؤلفون: Irene Keller, Kurt Wyler, Ludovic Gillet, Hugues Abriel, Morgan Yoann Edwin Chevalier, Sarah H. Vermij

المصدر: Scientific Data, vol. 5, pp. 180170
Chevalier, Morgan; Vermij, Sarah H.; Wyler, Kurt; Gillet, Ludovic; Keller, Irene; Abriel, Hugues (2018). Transcriptomic analyses of murine ventricular cardiomyocytes. Scientific data, 5(180170), p. 180170. Nature Publishing Group 10.1038/sdata.2018.170 <http://dx.doi.org/10.1038/sdata.2018.170>
Scientific Data

مصطلحات موضوعية: 0301 basic medicine, Genetically modified mouse, Statistics and Probability, Data Descriptor, ved/biology.organism_classification_rank.species, 610 Medicine & health, Library and Information Sciences, Education, Transcriptome, 03 medical and health sciences, CASK, Model organism, Gene, Ion channel, biology, ved/biology, Cell biology, Cardiovascular physiology, Computer Science Applications, 030104 developmental biology, Mechanisms of disease, biology.protein, 570 Life sciences, Gene expression, Statistics, Probability and Uncertainty, Dystrophin, Information Systems

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92ef9bb0fc9020fc2d19bf9ea5890f7a
https://serval.unil.ch/notice/serval:BIB_0C3727C1173F