المؤلفون: Marco Massari, Stefania Spila Alegiani, Cristina Morciano, Matteo Spuri, Pasquale Marchione, Patrizia Felicetti, Valeria Belleudi, Francesca Romana Poggi, Marco Lazzeretti, Michele Ercolanoni, Elena Clagnan, Emanuela Bovo, Gianluca Trifirò, Ugo Moretti, Giuseppe Monaco, Olivia Leoni, Roberto Da Cas, Fiorella Petronzelli, Loriana Tartaglia, Nadia Mores, Giovanna Zanoni, Paola Rossi, Sarah Samez, Cristina Zappetti, Anna Rosa Marra, Francesca Menniti Ippolito, TheShinISS-Vax|COVID Surveillance Group

المصدر: PLoS Medicine, Vol 19, Iss 7, p e1004056 (2022)

مصطلحات موضوعية: Medicine

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1549-1277; https://doaj.org/toc/1549-1676

URL الوصول: https://doaj.org/article/a5759782c15244bea3d815d3d233ba8c

المؤلفون: Marco Massari, Stefania Spila-Alegiani, Cristina Morciano, Matteo Spuri, Pasquale Marchione, Patrizia Felicetti, Valeria Belleudi, Francesca Romana Poggi, Marco Lazzeretti, Michele Ercolanoni, Elena Clagnan, Emanuela Bovo, Gianluca Trifirò, Ugo Moretti, Giuseppe Monaco, Olivia Leone, Roberto Da Cas, Fiorella Petronzelli, Loriana Tartaglia, Nadia Mores, Giovanna Zanoni, Paola Rossi, Sarah Samez, Cristina Zappetti, Anna Rosa Marra, Francesca Menniti-Ippolito

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::82a911f49467cbe75f27d073421c54f8
https://doi.org/10.1101/2022.02.07.22270020

المؤلفون: Xiaoming Zha (a), Doriano Lamba (b), Lili Zhanga (c), Yinghan Lou (a, Changxu Xua (c), Di Kanga (d), Li Chen (c), Yungen Xu (d), Luyong Zhang (a), Angela De Simone (e), Sarah Samez (b, Alessandro Pesaresi (b), Jure Stojan (g), Manuela G. Lopez (h), Javier Egea (h), Vincenza Andrisano (d), Manuela Bartolini (i)

المساهمون: Zha, Xiaoming, Lamba, Doriano, Zhang, Lili, Lou, Yinghan, Xu, Changxu, Kang, Di, Chen, Li, Xu, Yungen, Zhang, Luyong, De Simone, Angela, Samez, Sarah, Pesaresi, Alessandro, Stojan, Jure, Lopez, Manuela G., Egea, Javier, Andrisano, Vincenza, Bartolini, Manuela

المصدر: Journal of medicinal chemistry 59 (2016): 114–131. doi:10.1021/acs.jmedchem.5b01119
info:cnr-pdr/source/autori:Xiaoming Zha (a), Doriano Lamba (b), Lili Zhanga (c), Yinghan Lou (a,d), Changxu Xua (c), Di Kanga (d), Li Chen (c), Yungen Xu (d), Luyong Zhang (a), Angela De Simone (e), Sarah Samez (b,f), Alessandro Pesaresi (b), Jure Stojan (g), Manuela G. Lopez (h), Javier Egea (h), Vincenza Andrisano (d), and Manuela Bartolini (i)/titolo:Novel Tacrine-Benzofuran Hybrids as Potent Multitarget-Directed Ligands for the Treatment of Alzheimer's Disease:Design, Synthesis, Biological Evaluation and X-ray Crystallography/doi:10.1021%2Facs.jmedchem.5b01119/rivista:Journal of medicinal chemistry/anno:2016/pagina_da:114/pagina_a:131/intervallo_pagine:114–131/volume:59

مصطلحات موضوعية: Male, Models, Molecular, 0301 basic medicine, Drug Discovery, Pharmaceutical Science, multi-ligand-target-design, Pharmaceutical Science, Crystallography, X-Ray, Torpedo, 01 natural sciences, Mice, chemistry.chemical_compound, Models, Drug Discovery, Aspartic Acid Endopeptidases, Aspartic Acid Endopeptidase, Amyloid Precursor Protein Secretase, Cholinesterase Inhibitor, Benzofuran, Nootropic Agents, Mice, Inbred ICR, Crystallography, Behavior, Animal, biology, Medicine (all), Inbred ICR, Acetylcholinesterase, Tacrine, Molecular Medicine, Chemical and Drug Induced Liver Injury, Human, medicine.drug, Cell Survival, Stereochemistry, Alzheimer Disease, Amyloid Precursor Protein Secretases, Animals, Behavior, Animal, Benzofurans, Cell Line, Cholinesterase Inhibitors, X-Ray, Drug Design, Drug-Induced Liver Injury, Humans, Molecular, Structure-Activity Relationship, structure-base drug discovery, acetylcholinesterase, 03 medical and health sciences, In vivo, medicine, Structure–activity relationship, IC50, Cholinesterase, Nootropic Agent, 010405 organic chemistry, In vitro, 0104 chemical sciences, 030104 developmental biology, chemistry, biology.protein

وصف الملف: STAMPA

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2982356effe2a416f4043399aeca380
https://doi.org/10.1021/acs.jmedchem.5b01119

المؤلفون: Alessandro Pesaresi, Maria Laura Bolognesi, Jan Korabecny, Marinella Roberti, Vincenza Andrisano, Manuela Bartolini, Barbara Monti, Luis Emiliano Peña-Altamira, Sarah Samez, Eugenie Nepovimova, Christian Bergamini, Kamil Kuca, Elisa Uliassi, Doriano Lamba, Gregory E. Garcia, Romana Fato

المساهمون: Eugenie Nepovimova, Elisa Uliassi, Jan Korabecny, Luis Emiliano Peña-Altamira, Sarah Samez, Alessandro Pesaresi, Gregory E. Garcia, Manuela Bartolini, Vincenza Andrisano, Christian Bergamini, Romana Fato, Doriano Lamba, Marinella Roberti, Kamil Kuca, Barbara Monti, Maria Laura Bolognesi

المصدر: Journal of medicinal chemistry 57 (2014): 8576–8589. doi:10.1021/jm5010804
info:cnr-pdr/source/autori:Nepovímová, Eugenie; Uliassi, Elisa; Korábecný, Jan; Peña-Altamira, Luis Emiliano; Samez, Sarah; Pesaresi, Alessandro; Garcia, Gregory E.; Bartolini, Manuela; Andrisano, Vincenza; Bergamini, Christian; Fato, Romana; Lamba, Doriano; Roberti, Marinella; Kuca, Kamil; Monti, Barbara; Bolognesi, M. L./titolo:Multitarget Drug Design Strategy: Quinone-Tacrine Hybrids Designed To Block Amyloid-beta Aggregation and To Exert Anticholinesterase and Antioxidant Effects/doi:10.1021%2Fjm5010804/rivista:Journal of medicinal chemistry/anno:2014/pagina_da:8576/pagina_a:8589/intervallo_pagine:8576–8589/volume:57

مصطلحات موضوعية: X-ray crystal structure, Models, Molecular, Aché, Drug Evaluation, Preclinical, Chemistry Techniques, Synthetic, MULTITARGET-DIRECTED LIGANDS, Pharmacology, Crystallography, X-Ray, Antioxidants, Tacrine hybrids, chemistry.chemical_compound, Inhibitory Concentration 50, Drug Discovery, medicine, Animals, Humans, Molecular Targeted Therapy, Rats, Wistar, IC50, Neurons, Amyloid beta-Peptides, Chemistry, ALZHEIMER’S DISEASE, Quinones, Hep G2 Cells, Acetylcholinesterase, Naphthoquinone, In vitro, language.human_language, Quinone, Oxidative Stress, Cholinesterase, Abeta, BACE-1, Hepatoxicity, kinetic, Biochemistry, Blood-Brain Barrier, Tacrine, Drug Design, language, Molecular Medicine, Cholinesterase Inhibitors, Ex vivo, medicine.drug

وصف الملف: ELETTRONICO

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae9a310ccd9288b2eeb50fe56ae16810
http://hdl.handle.net/11585/384369

المؤلفون: Sarah Samez, Alessandro Pesaresi, Manuela Bartolini, Xiaoming Zha, Maria Laura Bolognesi, Doriano Lamba

المصدر: BioMet 14-XIV PharmacoBioMetallics, pp. 58–58, Pisa, 24-25 October 2014
info:cnr-pdr/source/autori:Sarah Samez, Alessandro Pesaresi, Manuela Bartolini, Xiaoming Zha, Maria Laura Bolognesi and Doriano Lamba/congresso_nome:BioMet 14-XIV PharmacoBioMetallics/congresso_luogo:Pisa/congresso_data:24-25 October 2014/anno:2014/pagina_da:58/pagina_a:58/intervallo_pagine:58–58

URL الوصول: https://explore.openaire.eu/search/publication?articleId=cnr_________::f8e886720196a1e9886a80206241b435
http://biomet14.farm.unipi.it/