-
1
المؤلفون: Sarah W. Li, Matthew W. Kemp, Susan J.S. Logan, Pooja Sharma Dimri, Navkaran Singh, Citra N.Z. Mattar, Pradip Dashraath, Harshaana Ramlal, Aniza P. Mahyuddin, Suren Kanayan, Sean W.D. Carter, Serene P.T. Thain, Erin L. Fee, Sebastian E. Illanes, Mahesh A. Choolani, Mary Rauff, Arijit Biswas, Jeffrey J.H. Low, Joseph S. Ng, Arundhati T. Gosavi, Zhongwei Huang, Preethi Rajendran, Kwok Weng Roy Ng, Jeslyn J.L. Wong, Grace M.F. Chan, Kelvin Zhi Xing Lee, Jeannie J.Y. Yap, Nurulhuda Ahmad, Shwetha Shanmugam, Rajeswari Kathirvel, Manisha Mathur, Whui Whui Lim, Min Yu Lim
المصدر: American Journal of Obstetrics and Gynecology.
مصطلحات موضوعية: Obstetrics and Gynecology
-
2
المؤلفون: Mark S. Forman, Peter Orth, Ulrich Iserloh, Yusheng Wu, Hongwu Wang, William J. Greenlee, Reshma Kuvelkar, Xia Chen, Jack D. Scott, John Meredith, Lana M. Rossiter, Lynn A. Hyde, Robert A. Hodgson, Andrew Stamford, Julie A. Stone, Irina Kazakevich, Ganfeng Wang, Eric M. Parker, Eric J. Gilbert, Kathleen Cox, Corey O. Strickland, Sarah W. Li, Meagan Slater, Qin Jiang, Johannes H. Voigt, Hong Mei, Andrew Brunskill, Matthew E. Kennedy, Misiaszek Jeffrey A, Jared N. Cumming
المصدر: Journal of Medicinal Chemistry. 59:10435-10450
مصطلحات موضوعية: Models, Molecular, 0301 basic medicine, High selectivity, Cathepsin D, Rats, Sprague-Dawley, Amyloid beta-Protein Precursor, Structure-Activity Relationship, 03 medical and health sciences, chemistry.chemical_compound, Dogs, Aspartate protease, Alzheimer Disease, Drug Discovery, Amyloid precursor protein, Animals, Humans, chemistry.chemical_classification, Dose-Response Relationship, Drug, Molecular Structure, Thiadiazines, biology, Cyclic S-Oxides, Rats, Macaca fascicularis, 030104 developmental biology, Enzyme, Biochemistry, chemistry, biology.protein, Molecular Medicine, Verubecestat, Clinical evaluation, Derivative (chemistry)
-
3
المؤلفون: Joel M. Harris, Xiaoping Zhou, John A. Morrow, Sue-Ing Lin, Marco A. S. Baptista, John M. Sanders, Xiaoping Zhang, Hong Mei, Mark W. Embrey, Sylvie M. Sur, Duane E. DeMong, Ravi P. Nargund, Alan Hruza, Heather E. Tiscia, Matthew J. Fell, Zhizhang Yin, Gautam Agnihotri, Honglu Zhang, Thomas J. Greshock, Jack D. Scott, Yinghui Lin, Zhi-Cai Shi, John A. Mccauley, Sarah W. Li, Ronald K. Chang, Mark T. Bilodeau, Michael W. Miller, Reshma Kuvelkar, Andrew Stamford, Marc Poirier, Hong Liu, Megan K. Macala, Kallol Basu, Li Xiao, Lynn A. Hyde, Jonathan T. Kern, Xing Dai, Christian Mirescu, Paul L. Walsh, Matthew E. Kennedy, John J. Renger, Zhiyong Hu, John Columbus, Robert E. Drolet, Eric M. Parker
المصدر: Journal of medicinal chemistry. 60(7)
مصطلحات موضوعية: 0301 basic medicine, Male, Indazoles, Leucine-rich repeat, Leucine-Rich Repeat Serine-Threonine Protein Kinase-2, 03 medical and health sciences, 0302 clinical medicine, Drug Discovery, Animals, Humans, c-Raf, Kinase activity, Enzyme Inhibitors, Rats, Wistar, biology, Cyclin-dependent kinase 4, Kinase, Chemistry, Cyclin-dependent kinase 2, Brain, Parkinson Disease, LRRK2, nervous system diseases, Rats, Molecular Docking Simulation, 030104 developmental biology, Protein kinase domain, Biochemistry, biology.protein, Molecular Medicine, 030217 neurology & neurosurgery
-
4
المؤلفون: Samuel Chackalamannil, Yan Xia, Hongwu Wang, Michael W. Miller, Charles Lee Jayne, Sarah W. Li, Jean E. Lachowicz, Andrew Stamford, William J. Greenlee, Jack D. Scott, Timothy J. Kowalski, George Boykow, Ruth A. Duffy, Brian D. Spar
المصدر: Bioorganic & Medicinal Chemistry Letters. 20:1278-1283
مصطلحات موضوعية: Cannabinoid receptor, Stereochemistry, medicine.medical_treatment, Clinical Biochemistry, Mice, Obese, Pharmaceutical Science, Biochemistry, Chemical synthesis, Eating, Mice, Structure-Activity Relationship, chemistry.chemical_compound, Piperidines, Receptor, Cannabinoid, CB1, In vivo, Drug Discovery, medicine, Animals, Potency, Obesity, Receptor, Molecular Biology, Chemistry, Organic Chemistry, Antagonist, Diet, Molecular Medicine, Cannabinoid, Piperidine, Protein Binding
-
5
المؤلفون: Tony Priestley, Vaccaro Henry A, Andrew Stamford, Deborra E Mullins, Michael W. Miller, Tin-Yau Chan, Robert A. Hodgson, Scott Jack D, William J. Greenlee, Liwu Hong, Mario Guzzi, Sarah W. Li, Eric M. Parker, Geoffrey B. Varty, Jay Weinstein, Sue-Ing Lin, Mckittrick Brian A
المصدر: Bioorganic & Medicinal Chemistry Letters. 19:6018-6022
مصطلحات موضوعية: Receptors, Vasopressin, Vasopressin, Stereochemistry, Clinical Biochemistry, Pharmaceutical Science, Biochemistry, Structure-Activity Relationship, chemistry.chemical_compound, Drug Discovery, Animals, Humans, Receptor, Molecular Biology, chemistry.chemical_classification, Arginine vasopressin receptor 1B, Sulfonamides, Tetrahydroisoquinoline, Antidiuretic Agents, Organic Chemistry, Antagonist, Rats, Sulfonamide, chemistry, Receptors, Oxytocin, Quinolines, Molecular Medicine, Piperidine, Linker, Antidiuretic Hormone Receptor Antagonists
-
6
المؤلفون: Peter Orth, Kathleen Cox, Corey Strickland, Rachael C. Hunter, Reshma Kuvelkar, Eric J. Gilbert, Lynn A. Hyde, Jared N. Cumming, Sarah W. Li, Chunli Huang, Eric M. Parker, Johannes H. Voigt, Yusheng Wu, Matthew E. Kennedy, Andrew Stamford, William J. Greenlee, Zhaoning Zhu, Dawit Tadesse, Liwu Hong, Babu Suresh D, Misiaszek Jeffrey A, Xia Chen, Tao Guo, Robert A. Hodgson, Jack D. Scott, Mckittrick Brian A, Leonard Favreau
المصدر: ACS medicinal chemistry letters. 3(11)
مصطلحات موضوعية: chemistry.chemical_compound, Chemistry, Drug discovery, mental disorders, Organic Chemistry, Drug Discovery, Aβ peptide, Systemic administration, Pharmacology, Penetrant (biochemical), Biochemistry
-
7
المؤلفون: Gamal E. Osman, Warren Ladiges, Sarah W. Li, Leroy Hood, David P. Jacobson, Anupam K. Dattamajumdar
المصدر: Immunogenetics. 44:432-440
مصطلحات موضوعية: Genetics, Subfamily, Base Sequence, Sequence analysis, Receptors, Antigen, T-Cell, alpha-beta, Pseudogene, Molecular Sequence Data, Immunology, Mice, Inbred Strains, Sequence alignment, Sequence Analysis, DNA, Biology, Blotting, Southern, Mice, Sequence logo, Multigene Family, Animals, Gene family, DNAJA2, Amino Acid Sequence, Cloning, Molecular, Sequence Alignment, Peptide sequence