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المؤلفون: Julia Bercher, Ralf Dechend, Nadine Haase, Ivo Bendix, Babbette LaMarca, Alexandra Gellhaus, Donald Foster, Stuart Milstein, Sarfraz Shaikh, Kristin Thiele, Michaela Golic, Florian Herse, Hanna Napieczynska, Arnd Heuser, Kristin Kräker, Dominik N. Müller, Jeff Rollins, Tuyen Nguyen, Svetlana Shulga-Morskaya, Mark W. Cunningham, Gerd Wallukat, Meray Serdar
المصدر: J Clin Invest
مصطلحات موضوعية: 0301 basic medicine, Angiotensin receptor, medicine.medical_specialty, Medizin, Angiotensinogen, Intrauterine growth restriction, Systemic inflammation, Preeclampsia, Rats, Sprague-Dawley, 03 medical and health sciences, 0302 clinical medicine, Pre-Eclampsia, Pregnancy, Internal medicine, medicine, Animals, Fetus, Proteinuria, business.industry, General Medicine, medicine.disease, Rats, Disease Models, Animal, 030104 developmental biology, Endocrinology, Blood pressure, Cardiovascular and Metabolic Diseases, 030220 oncology & carcinogenesis, Female, RNA Interference, Rats, Transgenic, medicine.symptom, business, Reperfusion injury, Research Article
وصف الملف: application/pdf
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المؤلفون: Kun Qian, Kallanthottathil G. Rajeev, Casey Trapp, Martin Maier, Donald Foster, Muthiah Manoharan, Christopher R. Brown, Vasant Jadhav, Satya Kuchimanchi, Mark K Schlegel, Alfica Sehgal, Sarfraz Shaikh, Stuart Milstein
المصدر: Molecular Therapy
مصطلحات موضوعية: 0301 basic medicine, Male, Small interfering RNA, Acetylgalactosamine, Mice, Transgenic, RNAi Therapeutics, 03 medical and health sciences, Mice, In vivo, RNA interference, Drug Discovery, Genetics, Gene silencing, Potency, Animals, GalNAc conjugates, Gene Silencing, RNA, Messenger, RNA, Small Interfering, Molecular Biology, Pharmacology, Chemistry, Cell biology, 030104 developmental biology, Gene Expression Regulation, Liver, Duplex (building), RNAi, siRNA, Argonaute Proteins, Hepatocytes, Molecular Medicine, Asialoglycoprotein receptor, RNA Interference, Original Article
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المؤلفون: Ralf Dechend, Mark W. Cunningham, Sarfraz Shaikh, Florian Herse, Nadine Haase, Dominik N. Müller, Tuyen Nguyen, Babbette LaMarca, Svetlana Shulga-Morskaya, Jeff Rollins, Don Foster, Stuart Milstein, Kristin Kräker, Michaela Golic
المصدر: Pregnancy Hypertension. 13:S63
مصطلحات موضوعية: Fetus, Small interfering RNA, business.industry, Obstetrics and Gynecology, Pharmacology, medicine.disease, Preeclampsia, Transgenic Model, RNAi Therapeutics, RNA interference, Internal Medicine, medicine, Gene silencing, business, Pregnancy disorder
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المؤلفون: Sarfraz Shaikh, David R. Corey, Keith T. Gagnon, Satya Kuchimanchi, Masayuki Matsui, Huiying Zhang, Muthiah Manoharan, Yongjun Chu, Bethany A. Janowski
المصدر: Nucleic Acids Research
مصطلحات موضوعية: Transcriptional Activation, Small RNA, RNA-dependent RNA polymerase, RNA activation, Biology, Gene Regulation, Chromatin and Epigenetics, Autoantigens, Histones, Transcription (biology), Cell Line, Tumor, Genetics, Humans, RNA, Antisense, Promoter Regions, Genetic, Group IV Phospholipases A2, Intron, RNA, RNA-Binding Proteins, Non-coding RNA, Molecular biology, Cell biology, RNA silencing, MicroRNAs, Cyclooxygenase 2, Argonaute Proteins, RNA, Small Untranslated
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98c36118288e1e4fa23ef09f2356bf7f
http://europepmc.org/articles/PMC3905862 -
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المؤلفون: Donald Foster, Sarfraz Shaikh, Gregory Hinkle, Jonathan O'Shea, Bo Pang, Akin Akinc, Rachel Meyers, Scott A Barros, William Cantley, Satya Kuchimanchi, Klaus Charisse, Sayda Elbashir, Amy C. Seila White, Rick Duncan, Amy Dell, Elena V Bulgakova, Muthiah Manoharan, Nate Taneja, Christopher B. Sherrill
المصدر: RNA. 18:557-568
مصطلحات موضوعية: Ribonuclease III, Small interfering RNA, RNA-induced silencing complex, Trans-acting siRNA, Article, RNAi Therapeutics, Mice, RNA interference, Animals, Humans, RNA-Induced Silencing Complex, Gene silencing, RNA, Small Interfering, Molecular Biology, Base Sequence, biology, PTEN Phosphohydrolase, Factor VII, Molecular biology, Rats, Cell biology, Mice, Inbred C57BL, RNA silencing, biology.protein, Female, RNA Interference, HeLa Cells, Dicer
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66d1ddea398856e39ca463c57213f984
https://doi.org/10.1261/rna.031120.111 -
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المؤلفون: Tracy Zimmermann, Kallanthottathil G. Rajeev, Qianfan Wang, Michael E. Jung, Jonathan O'Shea, Pachamuthu Kandasamy, Stuart Milstein, Amy Chan, Nate Taneja, Alexander V Kel'in, Ronald J. van der Sluis, Renta Hutabarat, Akin Akinc, Md. Rowshon Alam, Ligang Zhang, Martin Maier, Kevin Fitzgerald, Satya Kuchimanchi, Klaus Charisse, Menno Hoekstra, Theo J.C. Van Berkel, Sarfraz Shaikh, Jennifer L. S. Willoughby, Muthiah Manoharan, Jayaprakash K. Nair
المصدر: Journal of the American Chemical Society, vol 136, iss 49
Nair, JK; Willoughby, JLS; Chan, A; Charisse, K; Alam, MR; Wang, Q; et al.(2014). Multivalent N-acetylgalactosamine-conjugated siRNA localizes in hepatocytes and elicits robust RNAi-mediated gene silencing. Journal of the American Chemical Society, 136(49), 16958-16961. doi: 10.1021/ja505986a. UCLA: Retrieved from: http://www.escholarship.org/uc/item/54c114pcمصطلحات موضوعية: Small interfering RNA, Acetylgalactosamine, Oligonucleotide synthesis, Inbred C57BL, Small Interfering, Biochemistry, Catalysis, Mice, Colloid and Surface Chemistry, RNA interference, In vivo, Gene silencing, Animals, Gene Silencing, RNA, Small Interfering, Molecular Structure, Oligonucleotide, Chemistry, RNA, General Chemistry, Molecular biology, carbohydrates (lipids), Mice, Inbred C57BL, Chemical Sciences, Hepatocytes, Asialoglycoprotein receptor
وصف الملف: application/pdf
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c6771db5f680b0df7e430efacf19d93
https://escholarship.org/uc/item/54c114pc -
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المؤلفون: Richard G Duncan, Ligang Zhang, Ivan Zlatev, Kallanthottathil G. Rajeev, Muthiah Manoharan, Jeremy G. Lackey, Kathy McRae, Sarfraz Shaikh, Amy Dell
المصدر: Bioorganicmedicinal chemistry. 21(3)
مصطلحات موضوعية: Small interfering RNA, Clinical Biochemistry, Oligonucleotides, Pharmaceutical Science, Oligonucleotide synthesis, Biochemistry, chemistry.chemical_compound, Automation, Mice, RNA interference, Polyphosphates, Drug Discovery, Gene silencing, Animals, Humans, RNA, Small Interfering, Molecular Biology, Cells, Cultured, Molecular Structure, Oligonucleotide, Chemistry, Organic Chemistry, RNA, Combinatorial chemistry, In vitro, Molecular Medicine, DNA, HeLa Cells
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8دورية أكاديمية
المؤلفون: Nairy, Jayaprakash K., Willoughby, Jennifer L. S., Chan, Amy, Charisse, Klaus, Alam, Md. Rowshon, Qianfan Wang, Hoekstra, Menno, Kandasamy, Pachamuthu, Kel'in, Alexander V., Milstein, Stuart, Taneja, Nate, O'Shea, Jonathan, Sarfraz Shaikh, Ligang Zhang, van der Sluis, Ronald J., Jung, Michael E., Akinc, Akin, Hutabarat, Renta, Satya Kuchimanchi, Fitzgerald, Kevin
المصدر: Journal of the American Chemical Society; 12/10/2014, Vol. 136 Issue 49, p16958-16961, 4p
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المؤلفون: Keri Dufault, Sarfraz Shaikh, Brian Bettencourt, Nenad Svrzikapa, Akin Akinc, Rachel Meyers, Maple Gioia, Yosef Landesman, Satya Kuchimanchi, Xuemei Zhang, Renta Hutabarat, Armand B. Cognetta
المصدر: Silence
مصطلحات موضوعية: Small interfering RNA, Factor VII, Cell, Methodology, Biology, Molecular biology, Reverse transcription polymerase chain reaction, chemistry.chemical_compound, Real-time polymerase chain reaction, medicine.anatomical_structure, chemistry, Pharmacokinetics, In vivo, medicine, Gene silencing, Molecular Biology, Biotechnology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e689fb7d1b9e13e69bafec3f632790f
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