المؤلفون: Adam John Hockenberry, Brett Mahon, Dale L. Bixby, Emmanuel Okeke, Melissa L. Larson, Sari H. Enschede, Natasha Catherine Edwin, Jamile M. Shammo, Taha Alrifai, Duane C. Hassane

المصدر: Blood. 138:4647-4647

مصطلحات موضوعية: business.industry, Somatic cell, Myelodysplastic syndromes, Immunology, Cancer research, Medicine, Cell Biology, Hematology, business, medicine.disease, Biochemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::e22e878461ad53d45c72bfcd43d72e18
https://doi.org/10.1182/blood-2021-147470

المؤلفون: Shaji Kumar, Andrew W. Roberts, Ahmed Salem, Kevin J. Freise, Cyrille Touzeau, Jia Jia, Asher Chanan-Khan, Paulo Maciag, Elizabeth Punnoose, Wijith Munasinghe, Amit Agarwal, Thierry Facon, Sari H. Enschede, Maria Verdugo, Joel D. Leverson, Jeremy A. Ross, Jaclyn Cordero, Philippe Moreau, Simon J. Harrison

المصدر: Blood. 130:2392-2400

مصطلحات موضوعية: 0301 basic medicine, medicine.medical_specialty, Nausea, Immunology, Pharmacology, Biochemistry, Gastroenterology, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Refractory, hemic and lymphatic diseases, Internal medicine, Medicine, Adverse effect, Multiple myeloma, Dexamethasone, Lenalidomide, business.industry, Venetoclax, Bortezomib, Cell Biology, Hematology, medicine.disease, 030104 developmental biology, chemistry, 030220 oncology & carcinogenesis, medicine.symptom, business, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::a64efd4a1cbafd36902707604a249b84
https://doi.org/10.1182/blood-2017-06-788323

المؤلفون: Jalaja Potluri, Sari H. Enschede, Nicole Lamanna, Bruce D. Cheson, Elisa Cerri, Monali Desai, Constantine S. Tam

المصدر: The Oncologist

مصطلحات موضوعية: Oncology, Cancer Research, medicine.medical_specialty, Chronic lymphocytic leukemia, Targeted cancer agents, Antineoplastic Agents, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Risk Factors, Internal medicine, Medicine, Humans, Quinazolinones, CD20, Sulfonamides, Hematology, biology, business.industry, Venetoclax, Disease Management, medicine.disease, Bridged Bicyclo Compounds, Heterocyclic, Leukemia, Lymphocytic, Chronic, B-Cell, Tumor Burden, Tumor lysis syndrome, Leukemia, Academia‐Pharma Intersect: Hematologic Malignancies, chemistry, Proto-Oncogene Proteins c-bcl-2, Purines, 030220 oncology & carcinogenesis, Ibrutinib, biology.protein, Hematologic malignancies, business, Idelalisib, Tumor Lysis Syndrome, 030215 immunology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9ce537bce417e8bd3a5f5ace6738e3a
http://europepmc.org/articles/PMC5679833

المؤلفون: Rod A. Humerickhouse, Martin Dunbar, Ahmed Salem, Shekman Wong, Suresh Agarwal, Sari H. Enschede

المصدر: The Journal of Clinical Pharmacology. 57:484-492

مصطلحات موضوعية: 0301 basic medicine, Pharmacology, business.industry, Venetoclax, CYP3A, Chronic lymphocytic leukemia, Urine, medicine.disease, 03 medical and health sciences, chemistry.chemical_compound, 030104 developmental biology, 0302 clinical medicine, chemistry, Pharmacokinetics, 030220 oncology & carcinogenesis, Concomitant, Medicine, Pharmacology (medical), Dosing, Refractory Chronic Lymphocytic Leukemia, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::9d3d6c1bb665d138b2b70f1c8c88f63f
https://doi.org/10.1002/jcph.821

المؤلفون: Thomas Moehler, Fil Manuguid, Sari H. Enschede, Magdalena Ruiz, Luana Margotto Soares, Vicky Casey, Kriti Jindal

المصدر: Blood. 136:28-28

مصطلحات موضوعية: medicine.medical_specialty, education.field_of_study, Venetoclax, Gemtuzumab ozogamicin, business.industry, Immunology, Population, Decitabine, Cell Biology, Hematology, Biochemistry, chemistry.chemical_compound, European LeukemiaNet, chemistry, Internal medicine, medicine, Cytarabine, Medical history, Midostaurin, education, business, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::3f0b35bf4c40aee0071175f6191e24ca
https://doi.org/10.1182/blood-2020-135921

المؤلفون: Mary Ann Anderson, Ian J. Majewski, Lijian Yu, Jennifer R. Brown, Su Young Kim, Joshua A Fein, Jing Deng, Matthew S. Davids, David C.S. Huang, Andrew W. Roberts, Constantine S. Tam, John F. Seymour, Anthony Letai, Eric G. Si, David Westerman, Sari H. Enschede, David J. Segal

المصدر: Blood. 127:3215-3224

مصطلحات موضوعية: 0301 basic medicine, medicine.medical_specialty, Time Factors, Chronic lymphocytic leukemia, Immunology, Apoptosis, Biochemistry, Mice, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, immune system diseases, In vivo, Cell Line, Tumor, hemic and lymphatic diseases, Internal medicine, medicine, Animals, Humans, neoplasms, B cell, Mice, Knockout, Sulfonamides, Lymphoid Neoplasia, Hematology, Gene Expression Regulation, Leukemic, business.industry, Venetoclax, Cell Biology, Bridged Bicyclo Compounds, Heterocyclic, medicine.disease, Leukemia, Lymphocytic, Chronic, B-Cell, Leukemia, 030104 developmental biology, medicine.anatomical_structure, Proto-Oncogene Proteins c-bcl-2, chemistry, Drug Resistance, Neoplasm, 030220 oncology & carcinogenesis, Cancer research, Bone marrow, Tumor Suppressor Protein p53, business, Signal Transduction, BH3 Interacting Domain Death Agonist Protein

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33b2975c327ec9e5e474b3b29019f7dc
https://doi.org/10.1182/blood-2016-01-688796

المؤلفون: Steven Coutre, Johannes Schetelig, Sebastian Böttcher, Mehrdad Mobasher, Sari H. Enschede, Michael Hallek, Rod A. Humerickhouse, Talha Munir, John F. Seymour, Soham D. Puvvada, Maria Verdugo, Brenda Chyla, Andrew W. Roberts, Wojciech Jurczak, Gary Gordon, Clemens M. Wendtner, Ming Zhu, Barbara Eichhorst, Elisa Cerri, Monali Desai, William G. Wierda, Stephen P. Mulligan, Stephan Stilgenbauer

المصدر: The Lancet Oncology. 17:768-778

مصطلحات موضوعية: Adult, Male, 0301 basic medicine, medicine.medical_specialty, Population, Antineoplastic Agents, Neutropenia, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Internal medicine, medicine, Humans, education, Survival rate, Aged, Neoplasm Staging, Aged, 80 and over, Salvage Therapy, Sulfonamides, education.field_of_study, business.industry, Venetoclax, Middle Aged, Bridged Bicyclo Compounds, Heterocyclic, Prognosis, medicine.disease, Leukemia, Lymphocytic, Chronic, B-Cell, Fludarabine, Surgery, Survival Rate, 030104 developmental biology, Oncology, chemistry, Drug Resistance, Neoplasm, 030220 oncology & carcinogenesis, Alemtuzumab, Female, Chromosome Deletion, Neoplasm Recurrence, Local, Refractory Chronic Lymphocytic Leukemia, business, Febrile neutropenia, Chromosomes, Human, Pair 17, Follow-Up Studies, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0974f66c3c29a8c4db17b3947ba47bd5
https://doi.org/10.1016/s1470-2045(16)30019-5

المؤلفون: Lofti Benboubker, Ravi Vij, Cristina Gasparetto, Joseph R. Mikhael, Martin Dunbar, Sari H. Enschede, Shaji Kumar, Jeremy A. Ross, Cyrille Touzeau, Joel D. Leverson, Paulo Maciag, Maria Verdugo, Elizabeth Punnoose, Thierry Facon, Brigitte Pegourie, Tu Xu, Martine Amiot, Suresh Agarwal, Philippe Moreau, Stefanie Alzate, Jonathan L. Kaufman

المساهمون: Mayo Clinic [Rochester], Emory University [Atlanta, GA], Duke University [Durham], Mayo Clinic [Scottsdale], Mayo Clinic, Washington University in Saint Louis (WUSTL), Centre Hospitalier Universitaire [Grenoble] (CHU), Centre Hospitalier Régional Universitaire de Tours (CHRU TOURS), Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille), Regulation of Bcl2 and p53 Networks in Multiple Myeloma and Mantle Cell Lymphoma (CRCINA-ÉQUIPE 10), Centre de Recherche en Cancérologie et Immunologie Nantes-Angers (CRCINA), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Nantes - UFR de Médecine et des Techniques Médicales (UFR MEDECINE), Université de Nantes (UN)-Université de Nantes (UN)-Centre hospitalier universitaire de Nantes (CHU Nantes)-Centre National de la Recherche Scientifique (CNRS)-Université d'Angers (UA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Nantes - UFR de Médecine et des Techniques Médicales (UFR MEDECINE), Université de Nantes (UN)-Université de Nantes (UN)-Centre hospitalier universitaire de Nantes (CHU Nantes)-Centre National de la Recherche Scientifique (CNRS)-Université d'Angers (UA), Integrative Oncogenomics of Multiple Myeloma Pathogenesis and Progression (CRCINA-ÉQUIPE 11), Genentech, Inc., Genentech, Inc. [San Francisco], AbbVie Inc. [North Chicago, Illinois, USA], Centre Hospitalier Régional Universitaire de Tours (CHRU Tours), Bernardo, Elizabeth, Université d'Angers (UA)-Université de Nantes (UN)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Centre hospitalier universitaire de Nantes (CHU Nantes)-Université d'Angers (UA)-Université de Nantes (UN)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Centre hospitalier universitaire de Nantes (CHU Nantes)

المصدر: Blood
Blood, American Society of Hematology, 2017, 130 (22), pp.2401-2409. ⟨10.1182/blood-2017-06-788786⟩
Blood, 2017, 130 (22), pp.2401-2409. ⟨10.1182/blood-2017-06-788786⟩

مصطلحات موضوعية: 0301 basic medicine, Adult, Male, medicine.medical_specialty, Immunology, [SDV.CAN]Life Sciences [q-bio]/Cancer, Antineoplastic Agents, Pharmacology, Neutropenia, Biochemistry, Gastroenterology, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Refractory, [SDV.CAN] Life Sciences [q-bio]/Cancer, Internal medicine, medicine, Humans, Molecular Targeted Therapy, Multiple myeloma, Dexamethasone, Lenalidomide, Aged, Sulfonamides, Leukopenia, business.industry, Bortezomib, Venetoclax, Cell Biology, Hematology, Middle Aged, medicine.disease, Bridged Bicyclo Compounds, Heterocyclic, 3. Good health, 030104 developmental biology, chemistry, 030220 oncology & carcinogenesis, Female, medicine.symptom, Neoplasm Recurrence, Local, business, Multiple Myeloma, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aebcf29fac61cb8ae467a93dad3e4101
https://pubmed.ncbi.nlm.nih.gov/29191974

المؤلفون: Bhavani Krishnan, Durga Vighnay, Michael Jeffrey Cho, Sari H. Enschede, Marie Given, Bernadette Collins, J. P. Hodge, Katarzyna Bochenska, Tanya Partridge

المصدر: Journal of Clinical Oncology. 37:e19511-e19511

مصطلحات موضوعية: Clinical trial, Cancer Research, medicine.medical_specialty, Oncology, business.industry, medicine, Intensive care medicine, business, medicine.disease, Multiple myeloma

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::9e29fc1bf6bc74e6a6e192cadf1b7566
https://doi.org/10.1200/jco.2019.37.15_suppl.e19511

المؤلفون: Jackie Lee, Darren C. Phillips, Sha Jin, Morey L. Smith, Yu Xiao, Heather Maecker, Nathaniel D. Catron, Saul H. Rosenberg, David C.S. Huang, Michael J. Mitten, John F. Seymour, Anatol Oleksijew, Stephen K. Tahir, Andrew J. Souers, Peter Kovar, Kylie D. Mason, Gerard M. Sullivan, Lloyd T. Lam, Chang H. Park, Sarah G. Hymowitz, Jun Chen, Scott L. Ackler, Steven W. Elmore, Rod A. Humerickhouse, Brian D. Dayton, Andrew W. Roberts, Cheol-Min Park, Sari H. Enschede, Haichao Zhang, Hong Ding, Wayne J. Fairbrother, John Xue, Kennan C. Marsh, Seong Lin Khaw, Deepak Sampath, Erwin R. Boghaert, Chris Tse, Paul Nimmer, Michael D. Wendt, Joel D. Leverson

المساهمون: School of Physical and Mathematical Sciences

المصدر: Nature Medicine. 19:202-208

مصطلحات موضوعية: Blood Platelets, Cell Survival, Chronic lymphocytic leukemia, bcl-X Protein, Antineoplastic Agents, Apoptosis, Mice, SCID, Pharmacology, Biology, General Biochemistry, Genetics and Molecular Biology, Mice, chemistry.chemical_compound, Dogs, medicine, Animals, Humans, MCL1, Science::Chemistry::Biochemistry [DRNTU], Sulfonamides, Aniline Compounds, Navitoclax, Venetoclax, Cancer, General Medicine, Bridged Bicyclo Compounds, Heterocyclic, medicine.disease, Xenograft Model Antitumor Assays, Tumor Burden, Proto-Oncogene Proteins c-bcl-2, chemistry, Hematologic Neoplasms, Cancer cell, Female, Refractory Chronic Lymphocytic Leukemia, HeLa Cells

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad0d8497b8cfd427f85db3ecd891b9c2
https://doi.org/10.1038/nm.3048