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1
المؤلفون: Satenig Guler, Maria C. DiPoto, Alejandro Crespo, Richard Caldwell, Benjamin Doerfel, Nina Grossmann, Kevin Ho, Bayard Huck, Christopher CV Jones, Ruoxi Lan, Djordje Musil, Justin Potnick, Heike Schilke, Brian Sherer, Stephanie Simon, Christian Sirrenberg, Zhuo Zhang, Lesley Liu-Bujalski
المصدر: ACS Medicinal Chemistry Letters. 14:566-576
مصطلحات موضوعية: Organic Chemistry, Drug Discovery, Biochemistry
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المؤلفون: Momar Toure, Constantin Neagu, Kevin Ho, Susan Zhang, Filippos Porichis, Zhizhou Fang, Maria DiPoto, Reinaldo Jones, Eugene Chekler, Eva Maria Tanzer, Brian Sherer, Theresa Johnson, Djordje Musil, Bin Li, Ralf Schmidt, Hong Ma, Andrea Unzue Lopez, Yanping Wang, Satenig Guler, YuFang Xiao, Renate Henkes, Chia Lin Chu, Uma Mahesh Gundra, Long Li, Christine Katharina Maurer, Emily Friis, Christopher Jones, James Cummings, Bayard Huck
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::60c4b42c55d861e189da387afa4d82a1
https://doi.org/10.2139/ssrn.4382746 -
3دورية أكاديمية
المؤلفون: Thomas F. Durand-Reville, Alita A. Miller, John P. O'Donnell, Xiaoyun Wu, Mark A. Sylvester, Satenig Guler, Ramkumar Iyer, Adam B. Shapiro, Nicole M. Carter, Camilo Velez-Vega, Samir H. Mous
المصدر: Nature, Nature. 597(7878):698-702
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المؤلفون: Samir H. Moussa, Alita A. Miller, Janelle Comita-Prevoir, John P. O'Donnell, Richard A. Slayden, Peter S. Horanyi, Angela M. Tanudra, April Chen, Mark Sylvester, Nicole M. Carter, Camilo Velez-Vega, Wu Xiaoyun, Adam B. Shapiro, Hoan Huynh, Jason E. Cummings, Stephen J. Mayclin, Andrew D. Ferguson, Jan A. Romero, Satenig Guler, Jing Zhang, George L. Drusano, Sarah M. McLeod, Tommasi Ruben A, Henry S. Heine, Ramkumar Iyer, Thomas F. Durand-Reville
المصدر: Nature. 597(7878)
مصطلحات موضوعية: medicine.drug_class, Antibiotics, Drug resistance, medicine.disease_cause, beta-Lactamases, Microbiology, Cyclooctanes, Mice, Antibiotic resistance, Drug Resistance, Multiple, Bacterial, Gram-Negative Bacteria, medicine, Animals, Penicillin-Binding Proteins, Aza Compounds, Mice, Inbred BALB C, Multidisciplinary, biology, Molecular Structure, Chemistry, Pseudomonas aeruginosa, Rational design, biology.organism_classification, Antimicrobial, Anti-Bacterial Agents, Stenotrophomonas maltophilia, Drug Design, Porin, Female
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المؤلفون: Nelson B. Olivier, John Breen, Sameer Kawatkar, Satenig Guler, Linda G. Otterson, Martin F. Hentemann, James T. Loch, Gabriel Martínez-Botella, Thomas A. Keating, Andrew R. McKenzie, Oluyinka Green, Joseph V. Newman
المصدر: Journal of Medicinal Chemistry. 57:4584-4597
مصطلحات موضوعية: Models, Molecular, Staphylococcus aureus, Protein Conformation, Microbial Sensitivity Tests, Pyrimidinones, Plasma protein binding, Crystallography, X-Ray, Gram-Positive Bacteria, medicine.disease_cause, Thymidylate kinase, Mice, Structure-Activity Relationship, chemistry.chemical_compound, Bacterial Proteins, Piperidines, Biosynthesis, Drug Resistance, Bacterial, Drug Discovery, medicine, Animals, Structure–activity relationship, Binding site, IC50, chemistry.chemical_classification, Binding Sites, Stereoisomerism, Staphylococcal Infections, Anti-Bacterial Agents, Enzyme, chemistry, Biochemistry, Molecular Medicine, Nucleoside-Phosphate Kinase, Hydrophobic and Hydrophilic Interactions
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المؤلفون: Janelle Comita-Prevoir, Thomas F. Durand-Reville, Robert A. Giacobbe, Camilo Velez-Vega, Brendan Chen, Alita A. Miller, Robert E. McLaughlin, Tiffany Palmer, Boudewijn L. M. de Jonge, Ning Gao, Nicole M. Carter, Adam B. Shapiro, Samir H. Moussa, Nelson B. Olivier, John P. Mueller, Jason Thresher, John O'Donnell, Hoan Huynh, Beth Andrews, Satenig Guler, Tommasi Ruben A, Sushmita D. Lahiri, Sarah M. McLeod, Neil Bifulco, Joseph V. Newman, David E. Ehmann
المصدر: Nature microbiology. 2
مصطلحات موضوعية: 0301 basic medicine, Microbiology (medical), Acinetobacter baumannii, Models, Molecular, Gram-negative bacteria, medicine.drug_class, 030106 microbiology, Immunology, Antibiotics, Drug Evaluation, Preclinical, Drug resistance, beta-Lactams, Applied Microbiology and Biotechnology, Microbiology, beta-Lactamases, 03 medical and health sciences, Mice, Dogs, Enterobacteriaceae, Drug Resistance, Multiple, Bacterial, Gram-Negative Bacteria, Genetics, medicine, Animals, Humans, Penicillin-Binding Proteins, Vaborbactam, biology, Cell Biology, biology.organism_classification, Antimicrobial, Virology, Rats, Carbapenems, Sulbactam, Drug Design, Antibacterial activity, Gram-Negative Bacterial Infections, beta-Lactamase Inhibitors, Azabicyclo Compounds, Acinetobacter Infections
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المؤلفون: Yonghan Hu, Jennifer R. Thomason, Steve Tam, Priya S. Chockalingam, Erica Reifenberg, Manus Ipek, Jason Shaoyun Xiang, Huan-Qiu Li, Richard Sheldon, Li Xing, Elisabeth A. Morris, Joshua James Sabatini, Katy E. Georgiadis, Satenig Guler
المصدر: Bioorganic & Medicinal Chemistry Letters. 21:6800-6803
مصطلحات موضوعية: Male, Models, Molecular, Scaffold, Abstract design, Clinical Biochemistry, Pharmaceutical Science, Biochemistry, Rats, Sprague-Dawley, Structure-Activity Relationship, Pharmacokinetics, Cartilage explants, Matrix Metalloproteinase 13, Osteoarthritis, Drug Discovery, Animals, Humans, Protease Inhibitors, Molecular Biology, Aggrecanase, Sulfonamides, Chemistry, Biphenyl Compounds, Organic Chemistry, Proteoglycan degradation, Rats, Bioavailability, ADAM Proteins, Drug Design, ADAMTS4 Protein, Molecular Medicine, Proteoglycans, Procollagen N-Endopeptidase
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المؤلفون: Rajeev Hotchandani, Neal Jeffrey Green, Junqing Cui, Suzana Marusic, Wei Li, Yonghan Hu, Neelu Kaila, J. Perry Hall, Tam Steve Yik-Kai, Lih-Ling Lin, Jeffrey W. Pelker, Sang Hsu, Huan-Qiu Li, Adrian Huang, Jeffrey Scott Condon, Qin Wang, Jean-Baptiste Telliez, Junjun Wu, Satenig Guler
المصدر: Bioorganic & Medicinal Chemistry Letters. 19:3485-3488
مصطلحات موضوعية: Lipopolysaccharides, MAPK/ERK pathway, Clinical Biochemistry, Anti-Inflammatory Agents, Triazole, Pharmaceutical Science, Biochemistry, MAP3K8, Monocytes, Rats, Sprague-Dawley, chemistry.chemical_compound, Proto-Oncogene Proteins, Nitriles, Drug Discovery, Animals, Humans, Protein Kinase Inhibitors, Molecular Biology, chemistry.chemical_classification, MAP kinase kinase kinase, Tumor Necrosis Factor-alpha, Kinase, Organic Chemistry, Aromatic amine, Biological activity, MAP Kinase Kinase Kinases, Rats, chemistry, Quinolines, Molecular Medicine, Female, Signal transduction
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المؤلفون: John W. Cuozzo, Sang Hsu, Louis Leung, Tam Steve Yik-Kai, Jean-Baptiste Telliez, Neal Green, Kristin Janz, Jefferey Pelker, Yonghan Hu, Huan-Qiu Li, Junjun Wu, Satenig Guler, Diane Joseph-McCarthy, Suzana Marusic, Neelu Kaila, Qin Wang, Rajeev Hotchandani, Adrian Huang, Jennifer R. Thomason, J. Perry Hall, Lih-Ling Lin
المصدر: Journal of Medicinal Chemistry. 50:4728-4745
مصطلحات موضوعية: Models, Molecular, In Vitro Techniques, Crystallography, X-Ray, MAP3K8, Proinflammatory cytokine, Rats, Sprague-Dawley, Erlotinib Hydrochloride, Structure-Activity Relationship, Proto-Oncogene Proteins, Drug Discovery, medicine, Animals, Humans, Epidermal growth factor receptor, biology, MAP kinase kinase kinase, Tumor Necrosis Factor-alpha, Chemistry, Kinase, Anti-Inflammatory Agents, Non-Steroidal, Imidazoles, MAP Kinase Kinase Kinases, Protein Structure, Tertiary, Rats, ErbB Receptors, Biochemistry, Tumor progression, Aminoquinolines, Microsomes, Liver, Quinazolines, Cancer research, biology.protein, Molecular Medicine, Cyclin-dependent kinase 8, Female, Erlotinib, medicine.drug
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المؤلفون: Andrew R. McKenzie, John Breen, Thomas A. Keating, James Duffy, Linda G. Otterson, Oluyinka Green, Joseph V. Newman, Andrew Pate Owens, Sameer Kawatkar, Nelson B. Olivier, Bolin Geng, Jon Read, James T. Loch, Martin F. Hentemann, Felix A. Hernandez-Juan, Jacques Dumas, Satenig Guler, Gabriel Martínez-Botella, Ian K. Gowers, Diane Joseph-McCarthy, David W. Sheppard, Ovadia Lazari, Jacqueline Macritchie, Nicholas A. Larsen
المصدر: Journal of medicinal chemistry. 55(22)
مصطلحات موضوعية: Methicillin-Resistant Staphylococcus aureus, Models, Molecular, Staphylococcus aureus, Microbial Sensitivity Tests, medicine.disease_cause, Crystallography, X-Ray, Thymidylate kinase, Benzoates, Microbiology, Structure-Activity Relationship, Catalytic Domain, Drug Discovery, Streptococcus pneumoniae, medicine, Structure–activity relationship, Humans, chemistry.chemical_classification, Nucleoside-phosphate kinase, biology, Molecular Structure, Chemistry, Vancomycin Resistance, biology.organism_classification, Anti-Bacterial Agents, Enzyme, Enterococcus, Molecular Medicine, Nucleoside-Phosphate Kinase, Bacteria, Thymine
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