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المؤلفون: Menghao Huang, Kushan Chowdhury, Zhigang Fang, X. Charlie Dong, Ming O. Li, Suthat Liangpunsakul, Hyeong-Geug Kim
المصدر: Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 3, Pp 921-942 (2021)
Cellular and Molecular Gastroenterology and Hepatologyمصطلحات موضوعية: 0301 basic medicine, Sestrins, MPO, myeloperoxidase, Mitogen-Activated Protein Kinase Kinase 7, RC799-869, DMSO, dimethyl sulfoxide, FoxO, forkhead box O, Sesn1/2/3, sestrin1/2/3, medicine.disease_cause, TKO, triple knockout, Mice, PCR, polymerase chain reaction, 0302 clinical medicine, GSH, glutathione, Phosphorylation, NF-κB, nuclear factor kappa B, Original Research, Cat, catalase, Mice, Knockout, Sestrin, Gpx3, glutathione peroxidase 3, Il6, interleukin 6, WD, Western diet, biology, Chemistry, Kinase, Fatty liver, Tgfbr1, transforming growth factor beta receptor 1, Gastroenterology, Col1a1, collagen type 1 alpha 1, Nox1, NADPH oxidase 1, Diseases of the digestive system. Gastroenterology, Dgat2, diacylglycerol O-acyltransferase 2, Cell biology, Keap1, Kelch-like ECH-associated protein 1, C-Jun N-Terminal Kinase, Liver, Lipotoxicity, c-Jun N-terminal kinases, JNK, c-Jun N-terminal kinase, 030211 gastroenterology & hepatology, Disease Susceptibility, Signal transduction, NASH, nonalcoholic steatohepatitis, Gss, glutathione synthetase, Pdgfrb, platelet-derived growth factor receptor beta, Timp1, tissue inhibitor of metalloproteinase 1, Fasn, fatty acid synthase, Fatty Liver Disease, Sod, superoxide dismutase, Acta2, smooth muscle actin alpha 2, ER, endoplasmic reticulum, PA, palmitic acid, 03 medical and health sciences, 4-HNE, 4-hydroxynonenal, MKK, mitogen-activated protein kinase kinase, medicine, Animals, Humans, Srebp, sterol regulatory element-binding protein, Protein kinase A, KD, knockdown, MDA, malondialdehyde, Inflammation, KO, knockout, Hepatology, NRF2, nuclear factor erythroid 2-related like 2, JNK Mitogen-Activated Protein Kinases, Lipid Metabolism, medicine.disease, Tgfb1, transforming growth factor beta 1, WT, wild-type, mTORC, mechanistic target of rapamycin complex, Fatty Liver, AMPK, AMP-activated protein kinase, Disease Models, Animal, Oxidative Stress, Scd1, stearoyl-CoA desaturase 1, 030104 developmental biology, Gene Expression Regulation, Cytoprotection, Hepatocytes, biology.protein, BSA, bovine serum albumin, SD, standard deviation, DHE, dihydroethidium, PERK, protein kinase R-like endoplasmic reticulum kinase, Tnf, tumor necrosis factor, Biomarkers, Oxidative stress
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1574bc0f082fa7f7fd23bf88f6f9c6fc
http://www.sciencedirect.com/science/article/pii/S2352345X21000862 -
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المؤلفون: Marica Cariello, Antonio Moschetta, Elena Piccinin
المصدر: Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 5, Pp 1519-1539 (2021)
Cellular and Molecular Gastroenterology and Hepatologyمصطلحات موضوعية: 0301 basic medicine, HFD, high-fat diet, Peroxisome Proliferator-Activated Receptors, Nuclear Receptors, Receptors, Cytoplasmic and Nuclear, Review, AST, aspartate aminotransferase, RC799-869, FLINT, FXR ligand obeticholic acid for noncirrhotic, nonalcoholic steatohepatitis trial, SHP, small heterodimer partner, 0302 clinical medicine, Non-alcoholic Fatty Liver Disease, Nonalcoholic fatty liver disease, CCl4, carbon tetrachloride, MUFA, monounsaturated fatty acid, PNPLA3, polymorphisms in patatin-like phospholipase 3, Receptor, NOS, nitric oxide synthase, Liver X Receptors, Peroxisome Proliferator Activated Receptors (PPARs), CA, cholic acid, TNF, tumor necrosis factor, Bile acid, Nonalcoholic Steatohepatitis (NASH), Gastroenterology, SREBP1c, sterol regulatory element-binding protein 1c, WAT, white adipose tissue, NR, nuclear receptor, Diseases of the digestive system. Gastroenterology, Lipids, HSC, hepatic stellate cell, REGENERATE, Randomized Global Phase 3 Study to Evaluate the Impact on NASH With Fibrosis of Obeticholic Acid Treatment, OCA, obeticholic acid, NAFL, nonalcoholic fatty liver, BA, bile acid, LPS, lipopolysaccharide, 030211 gastroenterology & hepatology, NASH, nonalcoholic steatohepatitis, Metabolic Networks and Pathways, TLR, Toll-like receptor, ATP, adenosine triphosphate, Oxysterol, medicine.drug_class, HDL, high-density lipoprotein, Biology, CYP7A1, cytochrome P450 7A1, Farnesoid X Receptor (FXR), digestive system, APO-E2, apolipoprotein-E2, CDCA, chenodeoxycholic acid, 03 medical and health sciences, FXR, farnesoid X receptor, ALT, alanine aminotransferase, Liver X Receptor (LXR), medicine, Animals, Humans, Liver X receptor, SCD1, stearoyl-CoA desaturase 1, PPAR, peroxisome proliferator activated receptor, Hepatology, MCDD, methionine- and choline-deficient diet, medicine.disease, digestive system diseases, FGF, fibroblast growth factor, VLDLR, very-low-density lipoprotein receptor, 030104 developmental biology, CoA, Coenzyme A, Nuclear receptor, Gene Expression Regulation, Cancer research, Farnesoid X receptor, NAFLD, nonalcoholic fatty liver disease, Steatohepatitis, LXR, liver X receptor
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f63dcdb7df5791629395e4c7c05eb5e
http://www.sciencedirect.com/science/article/pii/S2352345X21000187 -
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المؤلفون: Hsin Ming Chen, Jeng Fan Lo, Ching Wen Chang, Yi Fen Chen, Tz Yu Kuo, Chung Ji Liu, Hao Yuan Chia, Chia Yi Chou, Pei Chun Huang, Tsai Ying Chen, Wan Chun Li, Lu Te Chuang, Yi Ta Hsieh, Jian Min Huang
المصدر: Neoplasia: An International Journal for Oncology Research, Vol 21, Iss 7, Pp 641-652 (2019)
Neoplasia (New York, N.Y.)مصطلحات موضوعية: PGAM1, Phosphoglycerate mutase 1, 0301 basic medicine, Cancer Research, LC–MS, Liquid chromatography-mass spectrophotometry, Carcinogenesis, 5-FU, 5-fluouracil, ALDH, Aldehyde dehydrogenase, ACACB, Acetyl-CoA carboxylase beta, INN, Silibinin, medicine.disease_cause, Mice, 0302 clinical medicine, EMT, Epithelial-mesenchymal transition, PDHA1, Pyruvate dehydrogenase E1 component α subunit, Pyruvic Acid, OxPhos, Oxidative phosphorylation, PKM2, Pyruvate kinase M2, PUFAs, Polyunsaturated fatty acids, Glycolysis, ENO, Enolase, DON, 6-diazo-5-oxo-L-norlucine, education.field_of_study, Chemistry, Kinase, ABC, ATP-binding cassette, MTT, 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide, ERK, Extracellular signal-regulated kinase, PKB/Akt, Protein kinase B, 4-NQO, 4-nitroquinoline 1-oxide, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, GC-FID, Gas chromatograph-flame ionization detector, MUFAs, Monounsaturated fatty acids, Mitochondria, NHOK, Normal human oral keratinocytes, SCD1, Stearoyl-CoA desaturase 1, 030220 oncology & carcinogenesis, PDC, Pyruvate dehydrogenase complex, Heterografts, SFAs, Saturated fatty acids, TCA, Tricarboxylic acid, GLUD1/2, Glutamine dehydrogenase 1/2, Original article, G3PDH, Glyceraldehyde-3-phosphate dehydrogenase, TCGA, The Cancer Genomic Atlas, Catalytic complex, Lactate dehydrogenase A, DLD, Dihydrolipoamide dehydrogenase, lcsh:RC254-282, DCA, Dicholoroacetate, 03 medical and health sciences, ECM, Extracellular matrix, FASN, Fatty acid synthase, CDDP, Cisplatin, Cell Line, Tumor, HNSCC, Head and neck squamous cell carcinoma, medicine, shRNA, short-hairpin RNA, Animals, Humans, Pyruvate Dehydrogenase (Lipoamide), TAXOL, Paclitaxel, Lactic Acid, SREBF1/2, Sterol regulatory element-binding transcription factor 1/2, education, Protein kinase B, DLAT, Dihydrolipoamide S-acetyltransferase, PDK1, Pyruvate dehydrogenase kinase 1, Cell Proliferation, PPP, Pentose phosphate pathway, L-Lactate Dehydrogenase, LDHA, Lactate dehydrogenase A, Squamous Cell Carcinoma of Head and Neck, Cell growth, hOSCC, human oral squamous cell carcinoma, Gluts, Glucose transporters, medicine.disease, Head and neck squamous-cell carcinoma, OCR, Oxygen consumption rate, EGCG, Epigallocatechin gallate, 030104 developmental biology, PFK1, Phosphofructokinase 1, OS, Overall survival, PDP1, Pyruvate dehydrogenase phosphatase 1, IC50, Half maximal inhibitory concentration, Cancer research, PEP, Phosphoenolpyruvate, GLS1, Glutaminase 1, ROS, Reactive oxygen species
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المؤلفون: Riemann, Anne, Rauschner, Mandy, Gießelmann, Marina, Reime, Sarah, Haupt, Verena, Thews, Oliver
المصدر: Neoplasia: An International Journal for Oncology Research, Vol 21, Iss 5, Pp 450-458 (2019)
Neoplasia (New York, N.Y.)مصطلحات موضوعية: Male, Original article, Scd2, stearoyl-CoA desaturase 2, Epithelial-Mesenchymal Transition, Snai1, snail family transcriptional repressor 1, Twist1, twist family bHLH transcription factor 1, lcsh:RC254-282, Cell Adhesion, Animals, Humans, Vimentin, Fh, fumarate hydratase, Acsl1, acyl-CoA synthetase long-chain family member 1, Zeb2, zinc finger E-box binding homeobox 2, Zeb1, zinc finger E-box binding homeobox 1, Cadherins, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, Gpi, glucose-6-phosphate isomerase, Rats, NGS, next-generation sequencing, Gene Expression Regulation, Neoplastic, Idh2, isocitrate dehydrogenase 2, Scd1, stearoyl-CoA desaturase 1, MIBG, meta-iodobenzylguanidine, Acidosis, Biomarkers
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المؤلفون: Sophie, Honeder, Tamara, Tomin, Laura, Nebel, Jürgen, Gindlhuber, Katarina, Fritz-Wallace, Maximilian, Schinagl, Christoph, Heininger, Matthias, Schittmayer, Nassim, Ghaffari-Tabrizi-Wizsy, Ruth, Birner-Gruenberger
المصدر: Molecular & Cellular Proteomics : MCP
مصطلحات موضوعية: Lung Neoplasms, FDR, false discovery rate, LD, lipid droplet, FASN, fatty acid synthase, TCA, tricarboxylic acid, Chick Embryo, IDH1, isocitrate dehydrogenase 1, Chorioallantoic Membrane, Carcinoma, Non-Small-Cell Lung, Spheroids, Cellular, Tumor Cells, Cultured, MUFA, monounsaturated fatty acid, Animals, Humans, SCD1, stearoyl-CoA desaturase 1, ATGL, adipose triglyceride lipase, KO, knockout, Research, HILPDA, hypoxia-inducible lipid droplet associated, FA, fatty acid, LFQ, label-free quantitation, glycolysis, GLUT, glucose transporter, PANCAN, pan-cancer, HIF, hypoxia-inducible factor, lung cancer, Glucose, ADPGK, ADP-dependent glucokinase, FADS2, fatty acid desaturase 2, fatty acid metabolism, spheroid, lipolysis, CAM, chorioallantoic membrane, Acyltransferases
URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::29d3b9b68dc7ed18d3b4083dd33e660a
https://pubmed.ncbi.nlm.nih.gov/33992777 -
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المؤلفون: Sven Göpel, G. Hege Thoresen, Xiao-Rong Peng, Hege G. Bakke, Eili Tranheim Kase, Per Kristian Lunde, Jenny Lund, Lars Eide, Roya Ghobadi, Arild C. Rustan, Gavin O’ Mahony, Parmeshwar B. Katare, Abel M. Mengeste
المصدر: Current Research in Pharmacology and Drug Discovery, Vol 2, Iss, Pp 100060-(2021)
Current Research in Pharmacology and Drug Discoveryمصطلحات موضوعية: AMPK, medicine.medical_specialty, Pyruvate dehydrogenase kinase, SERCA, ASM, acid-soluble metabolites, Skeletal muscle, Oxidative phosphorylation, RM1-950, Internal medicine, medicine, OCR, oxygen consumption rate, Obesity, Protein kinase A, SCD1, stearoyl-CoA desaturase 1, Beta oxidation, General Environmental Science, FCCP, 4-(trifluromethoxy)phenylhydrazone, Glucose metabolism, CE, cholesteryl ester, Chemistry, FA, fatty acid, OA, oleic acid, Type 2 diabetes, Metabolism, T2DM, type 2 diabetes mellitus, AMPK, AMP-activated protein kinase, Endocrinology, medicine.anatomical_structure, Lipid metabolism, Lipogenesis, General Earth and Planetary Sciences, Therapeutics. Pharmacology, SERCA, sarco(endo)plasmic reticulum Ca2+-ATPase, DAG, diacylglycerol, Research Paper
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9eb79b1aa486f3fccd8e118dcb4a026
http://www.sciencedirect.com/science/article/pii/S259025712100047X -
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المؤلفون: Amelie Isabelle Sylvie Sobczak, Alan J. Stewart, Terry K. Smith, Ramzi A. Ajjan, Samantha J. Pitt
المساهمون: British Heart Foundation, University of St Andrews. School of Medicine, University of St Andrews. Sir James Mackenzie Institute for Early Diagnosis, University of St Andrews. Institute of Behavioural and Neural Sciences, University of St Andrews. Biomedical Sciences Research Complex, University of St Andrews. Cellular Medicine Division
المصدر: Biochimica et Biophysica Acta. Molecular and Cell Biology of Lipids
مصطلحات موضوعية: 0301 basic medicine, Blood Glucose, Male, QH301 Biology, Gene Expression, Fatty Acids, Nonesterified, Body Mass Index, chemistry.chemical_compound, 0302 clinical medicine, LDL, low-density lipoprotein, GC–MS, Chemistry, HbA1c, glycated haemoglobin A1c, Fasting, Lipogenesis, RC Internal medicine, lipids (amino acids, peptides, and proteins), Female, GC-MS, T1DM, type-1 diabetes mellitus, Stearoyl-CoA Desaturase, Adult, medicine.medical_specialty, HbA1c, Adolescent, HDL, high-density lipoprotein, NDAS, 030209 endocrinology & metabolism, Serum Albumin, Human, Article, QH301, 03 medical and health sciences, SDG 3 - Good Health and Well-being, Internal medicine, Diabetes mellitus, Lipidomics, FFA, free fatty acid, medicine, Humans, Non-esterified fatty acid, SCD1, stearoyl-CoA desaturase 1, Molecular Biology, Triglycerides, Glycated Hemoglobin, Type 1 diabetes, Fatty acid metabolism, D5D, delta-(5)-desaturase, Cholesterol, FAME, fatty acid methyl ester, FA, fatty acid, Cholesterol, HDL, Lipid metabolism, Cell Biology, Cholesterol, LDL, medicine.disease, Lipid Metabolism, 030104 developmental biology, Endocrinology, Diabetes Mellitus, Type 1, Case-Control Studies, Gas chromatography–mass spectrometry, GC–MS, gas chromatography–mass spectrometry, HSA, human serum albumin, RC
وصف الملف: application/pdf
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المؤلفون: So Hee Ko, Hyun Jik Lee, Sang Hun Lee, Gee Euhn Choi, Young Hyun Jung, Ho Jae Han, Sei Jung Lee
المصدر: Redox Biology, Vol 13, Iss C, Pp 426-443 (2017)
Redox Biologyمصطلحات موضوعية: 0301 basic medicine, CM-H2DCFDA, 2′,7′-dichlorodihydrofluorescein diacetate, FFA, Free fatty acid, FASN, fatty acid synthase, Clinical Biochemistry, PBA, 4-phenyl butyric acid, Apoptosis, Biochemistry, Mice, MAGL, monoacylglycerol lipase, DGAT1, diglyceride acyltransferase 1, Mitophagy, CHOP, CCAAT-enhancer binding protein homologous protein, Fatty acid synthase (FASN), FOXO3, forkhead box, class O3, S.E.M, standard error of mean, Cyclic AMP Response Element-Binding Protein, Hypoxia, lcsh:QH301-705.5, CPT1A, carnitine palmitoyltransferase 1A, Caspase, NAC, N-acetyl-L-cysteine, Mesenchymal stem cell, lcsh:R5-920, UCB-hMSCs, umbilical cord blood-derived hMSCs, HNA, human nuclear antigen, biology, GPAT1, glycerol-3-phsphate acyltransferase 1, TMRE, tetramethylrhodamine ethyl ester, Fatty Acids, Forkhead Box Protein O3, BNIP3, Bcl2/adenovirus E1B 19 kDa protein-interacting protein 3, HIF-1α, hypoxia-inducible factor-1 alpha, Cell Hypoxia, Mitochondria, Cell biology, Fatty Acid Synthase, Type I, Fatty acid synthase, HMSCs, human mesenchymal stem cells, Bcl2/adenovirus E1B 19 kDa protein-interacting protein 3 (BNIP3), FOXO3, FITC, fluorescein isothiocyanate, Stem cell, medicine.symptom, Sterol Regulatory Element Binding Protein 1, lcsh:Medicine (General), Research Paper, eIF-2α, eukaryotic initiation factor 2 alpha, PBS, phosphate buffered solution, Mesenchymal Stem Cell Transplantation, Cell Line, PI, propidium iodide, PA, palmitic acid, 03 medical and health sciences, ROS, reactive oxygen species, TBST, tris-buffered saline containing 0.1% Tween-20, mtROS, mitochondrial ROS, Proto-Oncogene Proteins, CCCP, carbonyl cyanide m-chlorophenyl hydrazine, CHIP, chromatin immunoprecipitation, medicine, Animals, Humans, SCD1, stearoyl-CoA desaturase 1, CBP, CREB-binding protein, SREBP1, sterol regulatory element binding protein 1, Wound Healing, FA, fatty acid, FUNDC1, FUN14 domain containing 1, Organic Chemistry, Membrane Proteins, Mesenchymal Stem Cells, Lipid metabolism, Annexin V, FITC-conjugated annexinV, PINK1, PTEN-induced putative kinase1, Hypoxia (medical), Hypoxia-Inducible Factor 1, alpha Subunit, Molecular biology, BCA, bicinchoninic acid, NT, non-targeting, Oxygen, 030104 developmental biology, lcsh:Biology (General), biology.protein, Reactive Oxygen Species
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المؤلفون: Jeffrey R. Idle, Diren Beyoğlu, Georg Martin Fiedler, Thomas Pabst, Uta Ceglarek, Linda Kortz
المصدر: Pabst, Thomas; Kortz, Linda; Fiedler, Georg Martin; Ceglarek, Uta; Idle, Jeffrey; Beyoglu, Diren (2017). The plasma lipidome in acute myeloid leukemia at diagnosis in relation to clinical disease features. BBA clinical, 7, pp. 105-114. Elsevier 10.1016/j.bbacli.2017.03.002 <http://dx.doi.org/10.1016/j.bbacli.2017.03.002>
BBA Clinicalمصطلحات موضوعية: 0301 basic medicine, FAA, fatty acid amide, AA, arachidonic acid, TG, triacylglycerol (triglyceride), chemistry.chemical_compound, PC, phosphatidylcholine, PGF1α, prostaglandin 1α, 0302 clinical medicine, PCA, principal components analysis, Blast cell number, UPLC-ESI-QTOFMS, ultraperformance liquid chromatography-electrospray ionization-quadrupole time-of-flight mass spectrometry, hemic and lymphatic diseases, MUFA, monounsaturated fatty acid, DG, diacylglycerol, Prognostic risk, CML, chronic myelogenous leukemia, DIC, disseminated intravascular coagulation, 12-HEPE, 12-hydroxy-5Z,8Z,10E,14Z,17Z-eicosapentaenoic acid, 610 Medicine & health, AML, acute myeloid leukemia, chemistry.chemical_classification, GCMS, gas chromatography–mass spectrometry, Myeloid leukemia, EPA, eicosapentaenoic acid (20:5, 5Z,8Z,11Z,14Z,17Z), Regular Article, SCD1, stearoyl CoA desaturase 1, PLS-DA, projection to latent structures-discriminant analysis, Lipidome, FLC-QqLIT-MS, fast liquid chromatography-quadrupole linear ion-trap mass spectrometry, MRM, multiple reactions monitoring, Biochemistry, 030220 oncology & carcinogenesis, Molecular Medicine, Arachidonic acid, lipids (amino acids, peptides, and proteins), POEA, palmitoleoyl ethanolamide, Polyunsaturated fatty acid, ESI +, electrospray ionization positive mode, LPE, lysophosphatidylethanolamine, 2HG, (R)-2-hydroxyglutarate, PGH2, prostaglandin H2, MG, monoacylglycerol, Cer, ceramide, PE, phosphatidylethanolamine, CE, cholesterol ester, Pathology and Forensic Medicine, 03 medical and health sciences, PGF2α, prostaglandin F2α, Physiology (medical), 2OG, 2-oxoglutarate, Lipidomics, PUFA, polyunsaturated fatty acid, PGE2, prostaglandin E2, Fatty acids, TxB2, thromboxane B2, mPGES-1, microsomal prostaglandin E synthase-1, LPC, lysophosphatidylcholine, SM, sphingomyelin, Acute myeloid leukemia, Cholesterol, 12-LOX, 12-lipoxygenase, FAME, fatty acid methyl ester, Fatty acid, TxA2, thromboxane A2, OPLS-DA, orthogonal PLS-DA, CPT1a, carnitine palmitate transferase 1a, ALL, acute lymphoblastic leukemia, Sphingolipid, CoQ10, coenzyme Q10, ESI-, electrospray ionization negative mode, 8,9-DHET, 8,9-dihydroxy-5Z,11Z,14Z-eicosatrienoic acid, 030104 developmental biology, chemistry, FAB, French-American-British classification, DGLA, dihomo-γ-linoleic acid, Cancer research, Eicosanoids, FAO, fatty acid oxidation
وصف الملف: application/pdf
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المؤلفون: Jeffrey S. Flier, Bhavna N. Desai, Nicholas Douris, Marie L. Mather, Garima Singhal, Garret A. FitzGerald, Mikiko Watanabe, ffolliott M. Fisher, Hilde Vardeh, Imad Nasser, Thomas Lundasen, Eleftheria Maratos-Flier, Carsten Skarke, Darko Stevanovic, Andrew C. Adams
المصدر: Molecular Metabolism
Molecular Metabolism, Vol 6, Iss 11, Pp 1395-1406 (2017)مصطلحات موضوعية: 0301 basic medicine, Liver Cirrhosis, Male, WT, wild type, Alcoholic liver disease, Cirrhosis, FGF21, FGF21, fibroblast growth factor 21, FGF21-OE, mice overexpressing the FGF21 gene, CPT1α, carnitine palmitoyltransferase 1 alpha, chemistry.chemical_compound, Mice, Random Allocation, ChREBPβ, carbohydrate-responsive element-binding protein beta, 0302 clinical medicine, CD68, cluster of differentiation 68, Longitudinal Studies, 2. Zero hunger, Liver injury, Mice, Knockout, Fatty liver, UCP2, uncoupling protein 2, Binge ethanol consumption, Chronic ethanol consumption, Molecular Biology, Cell Biology, FAS, fatty acid synthase, 3. Good health, Liver, Female, Original Article, IP, intraperitoneal, LDC, Lieber–DeCarli diet, Fatty Liver, Alcoholic, Adult, medicine.medical_specialty, lcsh:Internal medicine, NAFLD, non-alcoholic fatty liver disease, ALD, alcoholic liver disease, Binge drinking, CYP2E1, cytochrome P450 family 2 subfamily E member 1, TNFα, tumor necrosis factor alpha, 030209 endocrinology & metabolism, SEM, standard error of the mean, MCP1, monocyte chemoattractant protein 1, ALDH1α1, aldehyde dehydrogenase 1 alpha 1, 03 medical and health sciences, Internal medicine, ALT, alanine aminotransferase, medicine, Animals, Humans, Ethanol metabolism, SREBP1c, sterol regulatory element-binding protein-1c, lcsh:RC31-1245, SCD1, stearoyl-CoA desaturase 1, Liver Diseases, Alcoholic, Ethanol, ADH 1 and 2, alcohol dehydrogenase 1 and 2, FGF21-KO, mice lacking the FGF21 gene, PPARα, peroxisome proliferator-activated receptor alpha, business.industry, medicine.disease, ACSS2, acyl-coenzyme a synthetase short-chain family member 2, Fibroblast Growth Factors, Mice, Inbred C57BL, SC, subcutaneous, 030104 developmental biology, Endocrinology, chemistry, CPT1β, carnitine palmitoyltransferase 1 beta, business