المؤلفون: Tse LV; Department of Molecular Microbiology and Immunology, Saint Louis University, St. Louis, MO 63014, USA., Hou YJ; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., McFadden E; Department of Molecular Biosciences, University of Texas at Austin, Austin, TX 78712, USA., Lee RE; Marsico Lung Institute, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Scobey TD; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Leist SR; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Martinez DR; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Meganck RM; Department of Molecular Microbiology and Immunology, Saint Louis University, St. Louis, MO 63014, USA., Schäfer A; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Yount BL; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Mascenik T; Marsico Lung Institute, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Powers JM; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Randell SH; Marsico Lung Institute, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Zhang Y; National Institute of Allergy and Infectious Disease, National Institute of Health, Bethesda, MD 20892, USA., Wang L; National Institute of Allergy and Infectious Disease, National Institute of Health, Bethesda, MD 20892, USA., Mascola J; National Institute of Allergy and Infectious Disease, National Institute of Health, Bethesda, MD 20892, USA., McLellan JS; Department of Molecular Biosciences, University of Texas at Austin, Austin, TX 78712, USA., Baric RS; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.

المصدر: Science translational medicine [Sci Transl Med] 2023 Sep 27; Vol. 15 (715), pp. eadg5567. Date of Electronic Publication: 2023 Sep 27.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE

مواضيع طبية MeSH: Middle East Respiratory Syndrome Coronavirus* , Chiroptera* , Coronavirus Infections*, Humans ; Animals ; Mice ; Dipeptidyl Peptidase 4/genetics ; Dipeptidyl Peptidase 4/metabolism ; Cryoelectron Microscopy ; Antibodies, Monoclonal/metabolism

المؤلفون: Feng Y; Institute for Immunity, Transplantation and Infection, Stanford University, Stanford, CA 94305, USA., Yuan M; Department of Integrative Structural and Computational Biology, Scripps Research Institute, La Jolla, CA 92037, USA., Powers JM; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Hu M; Institute for Immunity, Transplantation and Infection, Stanford University, Stanford, CA 94305, USA., Munt JE; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Arunachalam PS; Institute for Immunity, Transplantation and Infection, Stanford University, Stanford, CA 94305, USA., Leist SR; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Bellusci L; Division of Viral Products, Center for Biologics Evaluation and Research, Food and Drug Administration (FDA), Silver Spring, MD 20993, USA., Kim J; Division of Viral Products, Center for Biologics Evaluation and Research, Food and Drug Administration (FDA), Silver Spring, MD 20993, USA., Sprouse KR; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA., Adams LE; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Sundaramurthy S; Sino Biological US Inc., Wayne, PA 19087, USA., Zhu X; Department of Integrative Structural and Computational Biology, Scripps Research Institute, La Jolla, CA 92037, USA., Shirreff LM; New Iberia Research Center, University of Louisiana at Lafayette, New Iberia, LA 70560, USA., Mallory ML; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Scobey TD; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Moreno A; Division of Infectious Diseases, Department of Medicine, Emory University School of Medicine, Atlanta, GA 30322, USA., O'Hagan DT; GSK, Rockville, MD 20850, USA., Kleanthous H; Bill and Melinda Gates Foundation, Seattle, WA 98109, USA., Villinger FJ; New Iberia Research Center, University of Louisiana at Lafayette, New Iberia, LA 70560, USA., Veesler D; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA.; Howard Hughes Medical Institute, University of Washington, Seattle, WA 98195, USA., King NP; Department of Biochemistry, University of Washington, Seattle, WA 98195, USA.; Institute for Protein Design, University of Washington, Seattle, WA 98195, USA., Suthar MS; Department of Pediatrics, Emory Vaccine Center, Emory National Primate Research Center, Atlanta, GA 30329, USA., Khurana S; Division of Viral Products, Center for Biologics Evaluation and Research, Food and Drug Administration (FDA), Silver Spring, MD 20993, USA., Baric RS; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Wilson IA; Department of Integrative Structural and Computational Biology, Scripps Research Institute, La Jolla, CA 92037, USA., Pulendran B; Institute for Immunity, Transplantation and Infection, Stanford University, Stanford, CA 94305, USA.; Department of Pathology, Stanford University School of Medicine, Stanford University, Stanford, CA 94305, USA.; Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford University, Stanford, CA 94305, USA.

المصدر: Science translational medicine [Sci Transl Med] 2023 May 10; Vol. 15 (695), pp. eadg7404. Date of Electronic Publication: 2023 May 10.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE

مواضيع طبية MeSH: Severe acute respiratory syndrome-related coronavirus* , COVID-19*/prevention & control, Animals ; Humans ; Mice ; Broadly Neutralizing Antibodies ; COVID-19 Vaccines ; Macaca ; SARS-CoV-2 ; Immunization ; Vaccination ; Antibodies, Monoclonal ; Antibodies, Viral ; Antibodies, Neutralizing

SCR Organism: SARS-CoV-2 variants

المؤلفون: Li D; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA; Department of Medicine, Duke University School of Medicine, Durham, NC 27710, USA., Edwards RJ; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA; Department of Medicine, Duke University School of Medicine, Durham, NC 27710, USA., Manne K; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA; Department of Medicine, Duke University School of Medicine, Durham, NC 27710, USA., Martinez DR; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Schäfer A; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Alam SM; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA; Department of Medicine, Duke University School of Medicine, Durham, NC 27710, USA., Wiehe K; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA; Department of Medicine, Duke University School of Medicine, Durham, NC 27710, USA., Lu X; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA; Department of Medicine, Duke University School of Medicine, Durham, NC 27710, USA., Parks R; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA; Department of Medicine, Duke University School of Medicine, Durham, NC 27710, USA., Sutherland LL; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA; Department of Medicine, Duke University School of Medicine, Durham, NC 27710, USA., Oguin TH 3rd; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA; Department of Medicine, Duke University School of Medicine, Durham, NC 27710, USA., McDanal C; Department of Surgery, Duke University, Durham, NC 27710, USA., Perez LG; Department of Surgery, Duke University, Durham, NC 27710, USA., Mansouri K; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA; Department of Medicine, Duke University School of Medicine, Durham, NC 27710, USA., Gobeil SMC; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA; Department of Medicine, Duke University School of Medicine, Durham, NC 27710, USA., Janowska K; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA; Department of Medicine, Duke University School of Medicine, Durham, NC 27710, USA., Stalls V; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA; Department of Medicine, Duke University School of Medicine, Durham, NC 27710, USA., Kopp M; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA; Department of Medicine, Duke University School of Medicine, Durham, NC 27710, USA., Cai F; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA; Department of Medicine, Duke University School of Medicine, Durham, NC 27710, USA., Lee E; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA; Department of Medicine, Duke University School of Medicine, Durham, NC 27710, USA., Foulger A; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA; Department of Medicine, Duke University School of Medicine, Durham, NC 27710, USA., Hernandez GE; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA; Department of Medicine, Duke University School of Medicine, Durham, NC 27710, USA., Sanzone A; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA; Department of Medicine, Duke University School of Medicine, Durham, NC 27710, USA., Tilahun K; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA; Department of Medicine, Duke University School of Medicine, Durham, NC 27710, USA., Jiang C; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA; Department of Medicine, Duke University School of Medicine, Durham, NC 27710, USA., Tse LV; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Bock KW; Infectious Disease Pathogenesis Section, Comparative Medicine Branch, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA., Minai M; Infectious Disease Pathogenesis Section, Comparative Medicine Branch, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA., Nagata BM; Infectious Disease Pathogenesis Section, Comparative Medicine Branch, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA., Cronin K; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA; Department of Medicine, Duke University School of Medicine, Durham, NC 27710, USA., Gee-Lai V; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA; Department of Medicine, Duke University School of Medicine, Durham, NC 27710, USA., Deyton M; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA; Department of Medicine, Duke University School of Medicine, Durham, NC 27710, USA., Barr M; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA; Department of Medicine, Duke University School of Medicine, Durham, NC 27710, USA., Von Holle T; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA; Department of Medicine, Duke University School of Medicine, Durham, NC 27710, USA., Macintyre AN; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA; Department of Medicine, Duke University School of Medicine, Durham, NC 27710, USA., Stover E; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA; Department of Medicine, Duke University School of Medicine, Durham, NC 27710, USA., Feldman J; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA 02139, USA., Hauser BM; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA 02139, USA., Caradonna TM; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA 02139, USA., Scobey TD; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Rountree W; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA; Department of Medicine, Duke University School of Medicine, Durham, NC 27710, USA., Wang Y; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA; Department of Medicine, Duke University School of Medicine, Durham, NC 27710, USA., Moody MA; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA; Department of Pediatrics, Duke University School of Medicine, Durham, NC 27710, USA., Cain DW; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA; Department of Medicine, Duke University School of Medicine, Durham, NC 27710, USA., DeMarco CT; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA; Department of Medicine, Duke University School of Medicine, Durham, NC 27710, USA., Denny TN; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA; Department of Medicine, Duke University School of Medicine, Durham, NC 27710, USA., Woods CW; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA; Department of Medicine, Duke University School of Medicine, Durham, NC 27710, USA; Center for Applied Genomics and Precision Medicine, Duke University Medical Center, Durham, NC 27710, USA., Petzold EW; Center for Applied Genomics and Precision Medicine, Duke University Medical Center, Durham, NC 27710, USA., Schmidt AG; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA 02139, USA; Department of Microbiology, Harvard Medical School, Boston, MA 02115, USA., Teng IT; Vaccine Research Center, National Institute of Allergy and Infectious Diseases (NIAID), NIH, Bethesda, MD 20892, USA., Zhou T; Vaccine Research Center, National Institute of Allergy and Infectious Diseases (NIAID), NIH, Bethesda, MD 20892, USA., Kwong PD; Vaccine Research Center, National Institute of Allergy and Infectious Diseases (NIAID), NIH, Bethesda, MD 20892, USA; Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY 10032, USA., Mascola JR; Vaccine Research Center, National Institute of Allergy and Infectious Diseases (NIAID), NIH, Bethesda, MD 20892, USA., Graham BS; Vaccine Research Center, National Institute of Allergy and Infectious Diseases (NIAID), NIH, Bethesda, MD 20892, USA., Moore IN; Infectious Disease Pathogenesis Section, Comparative Medicine Branch, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA., Seder R; Vaccine Research Center, National Institute of Allergy and Infectious Diseases (NIAID), NIH, Bethesda, MD 20892, USA., Andersen H; BIOQUAL, Rockville, MD 20850, USA., Lewis MG; BIOQUAL, Rockville, MD 20850, USA., Montefiori DC; Department of Surgery, Duke University, Durham, NC 27710, USA., Sempowski GD; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA; Department of Medicine, Duke University School of Medicine, Durham, NC 27710, USA., Baric RS; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Acharya P; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA; Department of Surgery, Duke University, Durham, NC 27710, USA., Haynes BF; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA; Department of Medicine, Duke University School of Medicine, Durham, NC 27710, USA; Department of Immunology, Duke University School of Medicine, Durham, NC 27710, USA. Electronic address: barton.haynes@duke.edu., Saunders KO; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA; Department of Surgery, Duke University, Durham, NC 27710, USA; Department of Immunology, Duke University School of Medicine, Durham, NC 27710, USA; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC 27710, USA. Electronic address: kevin.saunders@duke.edu.

المصدر: Cell [Cell] 2021 Aug 05; Vol. 184 (16), pp. 4203-4219.e32. Date of Electronic Publication: 2021 Jun 18.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 0413066 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4172 (Electronic) Linking ISSN: 00928674 NLM ISO Abbreviation: Cell Subsets: MEDLINE

مواضيع طبية MeSH: Antibodies, Neutralizing/*immunology , SARS-CoV-2/*physiology , Spike Glycoprotein, Coronavirus/*immunology, Animals ; Antibodies, Viral/immunology ; Bronchoalveolar Lavage Fluid/chemistry ; COVID-19/pathology ; COVID-19/virology ; Cytokines/metabolism ; Female ; Haplorhini ; Humans ; Lung/pathology ; Lung/virology ; Male ; Mice ; Mice, Inbred BALB C ; Protein Domains ; Receptors, IgG/metabolism ; SARS-CoV-2/isolation & purification ; Spike Glycoprotein, Coronavirus/chemistry ; Viral Load ; Virus Replication

المؤلفون: Saunders KO; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, USA. kevin.saunders@duke.edu.; Department of Surgery, Duke University, Durham, NC, USA. kevin.saunders@duke.edu.; Department of Immunology, Duke University School of Medicine, Durham, NC, USA. kevin.saunders@duke.edu.; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC, USA. kevin.saunders@duke.edu., Lee E; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, USA.; Department of Medicine, Duke University School of Medicine, Durham, NC, USA., Parks R; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, USA.; Department of Medicine, Duke University School of Medicine, Durham, NC, USA., Martinez DR; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Li D; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, USA.; Department of Medicine, Duke University School of Medicine, Durham, NC, USA., Chen H; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, USA.; Department of Medicine, Duke University School of Medicine, Durham, NC, USA., Edwards RJ; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, USA.; Department of Medicine, Duke University School of Medicine, Durham, NC, USA., Gobeil S; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, USA.; Department of Medicine, Duke University School of Medicine, Durham, NC, USA., Barr M; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, USA.; Department of Medicine, Duke University School of Medicine, Durham, NC, USA., Mansouri K; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, USA.; Department of Medicine, Duke University School of Medicine, Durham, NC, USA., Alam SM; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, USA.; Department of Medicine, Duke University School of Medicine, Durham, NC, USA., Sutherland LL; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, USA.; Department of Medicine, Duke University School of Medicine, Durham, NC, USA., Cai F; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, USA.; Department of Medicine, Duke University School of Medicine, Durham, NC, USA., Sanzone AM; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, USA.; Department of Medicine, Duke University School of Medicine, Durham, NC, USA., Berry M; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, USA.; Department of Medicine, Duke University School of Medicine, Durham, NC, USA., Manne K; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, USA.; Department of Medicine, Duke University School of Medicine, Durham, NC, USA., Bock KW; Infectious Disease Pathogenesis Section, Comparative Medicine Branch, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD, USA., Minai M; Infectious Disease Pathogenesis Section, Comparative Medicine Branch, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD, USA., Nagata BM; Infectious Disease Pathogenesis Section, Comparative Medicine Branch, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD, USA., Kapingidza AB; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, USA.; Department of Medicine, Duke University School of Medicine, Durham, NC, USA., Azoitei M; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, USA.; Department of Medicine, Duke University School of Medicine, Durham, NC, USA., Tse LV; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Scobey TD; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Spreng RL; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, USA.; Department of Medicine, Duke University School of Medicine, Durham, NC, USA., Rountree RW; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, USA.; Department of Medicine, Duke University School of Medicine, Durham, NC, USA., DeMarco CT; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, USA.; Department of Medicine, Duke University School of Medicine, Durham, NC, USA., Denny TN; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, USA.; Department of Medicine, Duke University School of Medicine, Durham, NC, USA., Woods CW; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, USA.; Department of Medicine, Duke University School of Medicine, Durham, NC, USA.; Center for Applied Genomics and Precision Medicine, Duke University Medical Center, Durham, NC, USA., Petzold EW; Center for Applied Genomics and Precision Medicine, Duke University Medical Center, Durham, NC, USA., Tang J; Division of Viral Products, Center for Biologics Evaluation and Research (CBER), Food and Drug Administration, Silver Spring, MD, USA., Oguin TH 3rd; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, USA.; Department of Medicine, Duke University School of Medicine, Durham, NC, USA., Sempowski GD; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, USA.; Department of Medicine, Duke University School of Medicine, Durham, NC, USA., Gagne M; Vaccine Research Center, NIAID, NIH, Bethesda, MD, USA., Douek DC; Vaccine Research Center, NIAID, NIH, Bethesda, MD, USA., Tomai MA; Corporate Research Materials Lab, 3M Company, St Paul, MN, USA., Fox CB; Infectious Disease Research Institute, Seattle, WA, USA., Seder R; Vaccine Research Center, NIAID, NIH, Bethesda, MD, USA., Wiehe K; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, USA.; Department of Medicine, Duke University School of Medicine, Durham, NC, USA., Weissman D; Department of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Pardi N; Department of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Golding H; Division of Viral Products, Center for Biologics Evaluation and Research (CBER), Food and Drug Administration, Silver Spring, MD, USA., Khurana S; Division of Viral Products, Center for Biologics Evaluation and Research (CBER), Food and Drug Administration, Silver Spring, MD, USA., Acharya P; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, USA.; Department of Surgery, Duke University, Durham, NC, USA., Andersen H; BIOQUAL, Rockville, MD, USA., Lewis MG; BIOQUAL, Rockville, MD, USA., Moore IN; Infectious Disease Pathogenesis Section, Comparative Medicine Branch, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD, USA., Montefiori DC; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, USA.; Department of Surgery, Duke University, Durham, NC, USA., Baric RS; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Haynes BF; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC, USA. barton.haynes@duke.edu.; Department of Immunology, Duke University School of Medicine, Durham, NC, USA. barton.haynes@duke.edu.; Department of Medicine, Duke University School of Medicine, Durham, NC, USA. barton.haynes@duke.edu.

المصدر: Nature [Nature] 2021 Jun; Vol. 594 (7864), pp. 553-559. Date of Electronic Publication: 2021 May 10.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE

مواضيع طبية MeSH: Pandemics*, Antibodies, Neutralizing/*immunology , Betacoronavirus/*immunology , COVID-19/*immunology , COVID-19/*prevention & control , Common Cold/*prevention & control , Cross Reactions/*immunology , Viral Vaccines/*immunology, Adjuvants, Immunologic ; Administration, Intranasal ; Animals ; COVID-19/epidemiology ; COVID-19 Vaccines/immunology ; Common Cold/immunology ; Common Cold/virology ; Disease Models, Animal ; Female ; Humans ; Macaca/immunology ; Male ; Models, Molecular ; Nanoparticles/chemistry ; SARS-CoV-2/immunology ; Spike Glycoprotein, Coronavirus/chemistry ; Spike Glycoprotein, Coronavirus/immunology ; Trachea ; Vaccination

المؤلفون: Rappazzo CG; Adimab, LLC, Lebanon, NH 03766, USA., Tse LV; Department of Epidemiology, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Kaku CI; Adimab, LLC, Lebanon, NH 03766, USA., Wrapp D; Department of Molecular Biosciences, The University of Texas at Austin, Austin, TX 78712, USA., Sakharkar M; Adimab, LLC, Lebanon, NH 03766, USA., Huang D; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA., Deveau LM; Adimab, LLC, Lebanon, NH 03766, USA., Yockachonis TJ; Paul G. Allen School of Global Animal Health, Washington State University, Pullman, WA 99164, USA., Herbert AS; U.S. Army Medical Research Institute of Infectious Diseases, Frederick, MD 21702, USA.; The Geneva Foundation, Tacoma, WA 98402, USA., Battles MB; Adimab, LLC, Lebanon, NH 03766, USA., O'Brien CM; U.S. Army Medical Research Institute of Infectious Diseases, Frederick, MD 21702, USA.; The Geneva Foundation, Tacoma, WA 98402, USA., Brown ME; Adimab, LLC, Lebanon, NH 03766, USA., Geoghegan JC; Adimab, LLC, Lebanon, NH 03766, USA., Belk J; Adimab, LLC, Lebanon, NH 03766, USA., Peng L; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA., Yang L; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA., Hou Y; Department of Epidemiology, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Scobey TD; Department of Epidemiology, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Burton DR; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA.; IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA 92037, USA.; Consortium for HIV/AIDS Vaccine Development (CHAVD), The Scripps Research Institute, La Jolla, CA 92037, USA.; Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard, Cambridge, MA 02139, USA., Nemazee D; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA., Dye JM; U.S. Army Medical Research Institute of Infectious Diseases, Frederick, MD 21702, USA., Voss JE; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA., Gunn BM; Paul G. Allen School of Global Animal Health, Washington State University, Pullman, WA 99164, USA., McLellan JS; Department of Molecular Biosciences, The University of Texas at Austin, Austin, TX 78712, USA., Baric RS; Department of Epidemiology, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA. rbaric@email.unc.edu lgralins@email.unc.edu laura.walker@adimab.com.; Departments of Microbiology and Immunology, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Gralinski LE; Department of Epidemiology, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA. rbaric@email.unc.edu lgralins@email.unc.edu laura.walker@adimab.com., Walker LM; Adimab, LLC, Lebanon, NH 03766, USA. rbaric@email.unc.edu lgralins@email.unc.edu laura.walker@adimab.com.; Adagio Therapeutics, Inc., Waltham, MA 02451, USA.

المصدر: Science (New York, N.Y.) [Science] 2021 Feb 19; Vol. 371 (6531), pp. 823-829. Date of Electronic Publication: 2021 Jan 25.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-9203 (Electronic) Linking ISSN: 00368075 NLM ISO Abbreviation: Science Subsets: MEDLINE

مواضيع طبية MeSH: Antibodies, Monoclonal/*immunology , Antibodies, Viral/*immunology , Betacoronavirus/*immunology , Broadly Neutralizing Antibodies/*immunology , SARS-CoV-2/*immunology , Spike Glycoprotein, Coronavirus/*immunology, Angiotensin-Converting Enzyme 2/metabolism ; Animals ; Antibodies, Monoclonal/genetics ; Antibodies, Monoclonal/metabolism ; Antibodies, Viral/genetics ; Antibodies, Viral/metabolism ; Antibody Affinity ; Binding Sites ; Binding Sites, Antibody ; Broadly Neutralizing Antibodies/genetics ; Broadly Neutralizing Antibodies/metabolism ; COVID-19/prevention & control ; COVID-19/therapy ; Cell Surface Display Techniques ; Directed Molecular Evolution ; Epitopes/immunology ; Humans ; Immunization, Passive ; Immunoglobulin Fc Fragments/immunology ; Mice, Inbred BALB C ; Protein Domains ; Protein Engineering ; Receptors, Coronavirus/metabolism ; Severe acute respiratory syndrome-related coronavirus/immunology ; Severe Acute Respiratory Syndrome/immunology ; Severe Acute Respiratory Syndrome/prevention & control ; Severe Acute Respiratory Syndrome/therapy ; Spike Glycoprotein, Coronavirus/metabolism ; COVID-19 Serotherapy ; Mice

المؤلفون: Li D, Edwards RJ, Manne K, Martinez DR, Schäfer A, Alam SM, Wiehe K, Lu X, Parks R, Sutherland LL, Oguin TH, McDanal C, Perez LG, Mansouri K, Gobeil SMC, Janowska K, Stalls V, Kopp M, Cai F, Lee E, Foulger A, Hernandez GE, Sanzone A, Tilahun K, Jiang C, Tse LV, Bock KW, Minai M, Nagata BM, Cronin K, Gee-Lai V, Deyton M, Barr M, Holle TV, Macintyre AN, Stover E, Feldman J, Hauser BM, Caradonna TM, Scobey TD, Rountree W, Wang Y, Moody MA, Cain DW, DeMarco CT, Denny T, Woods CW, Petzold EW, Schmidt AG, Teng IT, Zhou T, Kwong PD, Mascola JR, Graham BS, Moore IN, Seder R, Andersen H, Lewis MG, Montefiori DC, Sempowski GD, Baric RS, Acharya P, Haynes BF, Saunders KO

المصدر: BioRxiv : the preprint server for biology [bioRxiv] 2021 Feb 18. Date of Electronic Publication: 2021 Feb 18.

نوع المنشور: Preprint

بيانات الدورية: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

المؤلفون: Saunders KO, Lee E, Parks R, Martinez DR, Li D, Chen H, Edwards RJ, Gobeil S, Barr M, Mansouri K, Alam SM, Sutherland LL, Cai F, Sanzone AM, Berry M, Manne K, Kapingidza AB, Azoitei M, Tse LV, Scobey TD, Spreng RL, Rountree RW, DeMarco CT, Denny TN, Woods CW, Petzold EW, Oguin TH, Sempowski GD, Gagne M, Douek DC, Tomai MA, Fox CB, Seder R, Wiehe K, Weissman D, Pardi N, Acharya P, Andersen H, Lewis MG, Moore IN, Montefiori DC, Baric RS, Haynes BF

المصدر: BioRxiv : the preprint server for biology [bioRxiv] 2021 Feb 17. Date of Electronic Publication: 2021 Feb 17.

نوع المنشور: Preprint

بيانات الدورية: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

المؤلفون: Rappazzo CG; Adimab LLC, Lebanon, NH 03766, USA., Tse LV; Department of Epidemiology, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Kaku CI; Adimab LLC, Lebanon, NH 03766, USA., Wrapp D; Department of Molecular Biosciences, The University of Texas at Austin, Austin, TX 78712, USA., Sakharkar M; Adimab LLC, Lebanon, NH 03766, USA., Huang D; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA., Deveau LM; Adimab LLC, Lebanon, NH 03766, USA., Yockachonis TJ; Paul G. Allen School of Global Animal Health, Washington State University, Pullman, WA 99164, USA., Herbert AS; U.S. Army Medical Research Institute of Infectious Diseases, Frederick, MD 21702, USA.; The Geneva Foundation, 917 Pacific Avenue, Tacoma, WA 98402, USA., Battles MB; Adimab LLC, Lebanon, NH 03766, USA., O'Brien CM; U.S. Army Medical Research Institute of Infectious Diseases, Frederick, MD 21702, USA.; The Geneva Foundation, 917 Pacific Avenue, Tacoma, WA 98402, USA., Brown ME; Adimab LLC, Lebanon, NH 03766, USA., Geoghegan JC; Adimab LLC, Lebanon, NH 03766, USA., Belk J; Adimab LLC, Lebanon, NH 03766, USA., Peng L; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA., Yang L; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA., Scobey TD; Department of Epidemiology, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Burton DR; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA.; IAVI Neutralizing Antibody Center, The Scripps Research Institute, La Jolla, CA 92037, USA.; Consortium for HIV/AIDS Vaccine Development (CHAVD), The Scripps Research Institute, La Jolla, CA 92037, USA.; Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard, Cambridge, MA 02139, USA., Nemazee D; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA., Dye JM; U.S. Army Medical Research Institute of Infectious Diseases, Frederick, MD 21702, USA., Voss JE; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA., Gunn BM; Paul G. Allen School of Global Animal Health, Washington State University, Pullman, WA 99164, USA., McLellan JS; Department of Molecular Biosciences, The University of Texas at Austin, Austin, TX 78712, USA., Baric RS; Department of Epidemiology, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.; Departments of Microbiology and Immunology, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Gralinski LE; Department of Epidemiology, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Walker LM; Adimab LLC, Lebanon, NH 03766, USA.; Adagio Therapeutics, Inc., Waltham, MA 02451, USA.

المصدر: BioRxiv : the preprint server for biology [bioRxiv] 2020 Nov 17. Date of Electronic Publication: 2020 Nov 17.

نوع المنشور: Preprint

بيانات الدورية: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

المؤلفون: Edwards CE; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599., Yount BL; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599., Graham RL; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599., Leist SR; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599., Hou YJ; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599., Dinnon KH 3rd; Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599., Sims AC; Chemical and Biological Signatures Division, Pacific Northwest National Laboratory, Richland, WA 99354., Swanstrom J; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599., Gully K; Department of Comparative Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599., Scobey TD; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599., Cooley MR; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599., Currie CG; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599., Randell SH; Marsico Lung Institute, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599., Baric RS; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599; rbaric@email.unc.edu.; Department of Microbiology and Immunology, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599.; Rapidly Emerging Antiviral Drug Discovery Initiative, University of North Carolina, Chapel Hill, NC 27599.

المصدر: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2020 Oct 27; Vol. 117 (43), pp. 26915-26925. Date of Electronic Publication: 2020 Oct 12.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

مواضيع طبية MeSH: Virus Replication*/drug effects, Alphacoronavirus/*physiology , Coronavirus Infections/*virology , Disease Susceptibility/*virology, Adenosine Monophosphate/analogs & derivatives ; Adenosine Monophosphate/pharmacology ; Alanine/analogs & derivatives ; Alanine/pharmacology ; Alphacoronavirus/genetics ; Alphacoronavirus/growth & development ; Animals ; Cells, Cultured ; Chlorocebus aethiops ; Coronavirus Infections/transmission ; Gene Expression ; Host Specificity ; Humans ; Luminescent Proteins/genetics ; Mice ; Vero Cells

SCR Organism: Swine acute diarrhea syndrome coronavirus

المؤلفون: Agnihothram S; Department of Epidemiology., Gopal R, Yount BL Jr, Donaldson EF, Menachery VD, Graham RL, Scobey TD, Gralinski LE, Denison MR, Zambon M, Baric RS

المصدر: The Journal of infectious diseases [J Infect Dis] 2014 Apr 01; Vol. 209 (7), pp. 995-1006. Date of Electronic Publication: 2013 Nov 18.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Oxford University Press Country of Publication: United States NLM ID: 0413675 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1537-6613 (Electronic) Linking ISSN: 00221899 NLM ISO Abbreviation: J Infect Dis Subsets: MEDLINE

مواضيع طبية MeSH: Antigens, Viral/*immunology , Coronaviridae/*immunology , Nucleocapsid Proteins/*immunology , Spike Glycoprotein, Coronavirus/*immunology, Animals ; Antibodies, Viral/blood ; Blotting, Western ; Chiroptera ; Coronaviridae/isolation & purification ; Coronavirus Nucleocapsid Proteins ; Cross Reactions ; Enzyme-Linked Immunosorbent Assay ; Humans ; Mice ; Mice, Inbred BALB C ; Middle Aged ; Neutralization Tests