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المؤلفون: Foster JH; Texas Children's Cancer and Hematology Centers, Department of Pediatrics, Section of Hematology and Oncology, Baylor College of Medicine, Houston, TX 77030, USA., Barbieri E; Texas Children's Cancer and Hematology Centers, Department of Pediatrics, Section of Hematology and Oncology, Baylor College of Medicine, Houston, TX 77030, USA., Zhang L; Texas Children's Cancer and Hematology Centers, Department of Pediatrics, Section of Hematology and Oncology, Baylor College of Medicine, Houston, TX 77030, USA., Scorsone KA; Texas Children's Cancer and Hematology Centers, Department of Pediatrics, Section of Hematology and Oncology, Baylor College of Medicine, Houston, TX 77030, USA., Moreno-Smith M; Texas Children's Cancer and Hematology Centers, Department of Pediatrics, Section of Hematology and Oncology, Baylor College of Medicine, Houston, TX 77030, USA., Zage P; Department of Pediatrics, Division of Hematology-Oncology, University of California San Diego, La Jolla, CA 92024, USA.; Peckham Center for Cancer and Blood Disorders, Rady Children's Hospital, San Diego, CA 92123, USA., Horton TM; Texas Children's Cancer and Hematology Centers, Department of Pediatrics, Section of Hematology and Oncology, Baylor College of Medicine, Houston, TX 77030, USA.

المصدر: International journal of molecular sciences [Int J Mol Sci] 2021 Jun 18; Vol. 22 (12). Date of Electronic Publication: 2021 Jun 18.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

مواضيع طبية MeSH: Antineoplastic Agents/*therapeutic use , Cyclopentanes/*therapeutic use , Enzyme Inhibitors/*therapeutic use , Neuroblastoma/*drug therapy , Pyrimidines/*therapeutic use, Animals ; Antineoplastic Agents/pharmacology ; Apoptosis/drug effects ; Cell Cycle/drug effects ; Cell Line, Tumor ; Cyclopentanes/pharmacology ; Enzyme Inhibitors/pharmacology ; Humans ; Mice ; NEDD8 Protein/antagonists & inhibitors ; NEDD8 Protein/metabolism ; Pyrimidines/pharmacology ; Tumor Suppressor Protein p53/metabolism

المؤلفون: Sack LM; Division of Genetics, Brigham and Women's Hospital, Howard Hughes Medical Institute, Department of Genetics, Harvard Medical School, 77 Avenue Louis Pasteur, Boston, MA 02115, USA., Davoli T; Division of Genetics, Brigham and Women's Hospital, Howard Hughes Medical Institute, Department of Genetics, Harvard Medical School, 77 Avenue Louis Pasteur, Boston, MA 02115, USA., Li MZ; Division of Genetics, Brigham and Women's Hospital, Howard Hughes Medical Institute, Department of Genetics, Harvard Medical School, 77 Avenue Louis Pasteur, Boston, MA 02115, USA., Li Y; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02115, USA; Shandong Provincial Hospital affiliated to Shandong University, Jinan 250021, China., Xu Q; Division of Genetics, Brigham and Women's Hospital, Howard Hughes Medical Institute, Department of Genetics, Harvard Medical School, 77 Avenue Louis Pasteur, Boston, MA 02115, USA., Naxerova K; Division of Genetics, Brigham and Women's Hospital, Howard Hughes Medical Institute, Department of Genetics, Harvard Medical School, 77 Avenue Louis Pasteur, Boston, MA 02115, USA., Wooten EC; Division of Genetics, Brigham and Women's Hospital, Howard Hughes Medical Institute, Department of Genetics, Harvard Medical School, 77 Avenue Louis Pasteur, Boston, MA 02115, USA., Bernardi RJ; Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Department of Molecular and Human Genetics, Dan L. Duncan Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA., Martin TD; Division of Genetics, Brigham and Women's Hospital, Howard Hughes Medical Institute, Department of Genetics, Harvard Medical School, 77 Avenue Louis Pasteur, Boston, MA 02115, USA., Chen T; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02115, USA; Laura and Isaac Perlmutter Cancer Center, New York University Langone Medical Center, New York, NY, USA., Leng Y; Division of Genetics, Brigham and Women's Hospital, Howard Hughes Medical Institute, Department of Genetics, Harvard Medical School, 77 Avenue Louis Pasteur, Boston, MA 02115, USA., Liang AC; Division of Genetics, Brigham and Women's Hospital, Howard Hughes Medical Institute, Department of Genetics, Harvard Medical School, 77 Avenue Louis Pasteur, Boston, MA 02115, USA., Scorsone KA; Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Department of Molecular and Human Genetics, Dan L. Duncan Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA., Westbrook TF; Verna and Marrs McLean Department of Biochemistry and Molecular Biology, Department of Molecular and Human Genetics, Dan L. Duncan Cancer Center, Baylor College of Medicine, Houston, TX 77030, USA., Wong KK; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02115, USA; Laura and Isaac Perlmutter Cancer Center, New York University Langone Medical Center, New York, NY, USA., Elledge SJ; Division of Genetics, Brigham and Women's Hospital, Howard Hughes Medical Institute, Department of Genetics, Harvard Medical School, 77 Avenue Louis Pasteur, Boston, MA 02115, USA. Electronic address: selledge@genetics.med.harvard.edu.

المصدر: Cell [Cell] 2018 Apr 05; Vol. 173 (2), pp. 499-514.e23. Date of Electronic Publication: 2018 Mar 22.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 0413066 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4172 (Electronic) Linking ISSN: 00928674 NLM ISO Abbreviation: Cell Subsets: MEDLINE

مواضيع طبية MeSH: Aneuploidy*, Neoplasms/*pathology, Animals ; Cell Line, Tumor ; Cell Proliferation ; Chromosome Mapping ; Chromosomes/genetics ; E2F1 Transcription Factor/antagonists & inhibitors ; E2F1 Transcription Factor/genetics ; E2F1 Transcription Factor/metabolism ; Female ; Gene Library ; Genomics ; Humans ; Keratins/metabolism ; Mice ; Mice, Inbred NOD ; Mice, SCID ; Oncogenes ; Open Reading Frames/genetics ; RNA Interference ; RNA, Small Interfering/metabolism

المؤلفون: Moreno-Smith M; Department of Pediatrics, Section of Hematology-Oncology, Texas Children's Cancer and Hematology Centers, Baylor College of Medicine, Houston, Texas., Lakoma A; Division of Pediatric Surgery, Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, Texas., Chen Z; Department of Pediatrics, Section of Hematology-Oncology, Texas Children's Cancer and Hematology Centers, Baylor College of Medicine, Houston, Texas., Tao L; Department of Pediatrics, Section of Hematology-Oncology, Texas Children's Cancer and Hematology Centers, Baylor College of Medicine, Houston, Texas., Scorsone KA; Department of Pediatrics, Section of Hematology-Oncology, Texas Children's Cancer and Hematology Centers, Baylor College of Medicine, Houston, Texas., Schild L; Department of Oncogenomics, Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands., Aviles-Padilla K; Department of Pediatrics, Center for Human Immunobiology, Texas Children's Hospital, Baylor College of Medicine, Houston, Texas., Nikzad R; Department of Pediatrics, Center for Human Immunobiology, Texas Children's Hospital, Baylor College of Medicine, Houston, Texas., Zhang Y; Department of Pediatrics, Section of Hematology-Oncology, Texas Children's Cancer and Hematology Centers, Baylor College of Medicine, Houston, Texas., Chakraborty R; Department of Pediatrics, Section of Hematology-Oncology, Texas Children's Cancer and Hematology Centers, Baylor College of Medicine, Houston, Texas., Molenaar JJ; Department of Oncogenomics, Academic Medical Center, University of Amsterdam, Amsterdam, the Netherlands., Vasudevan SA; Division of Pediatric Surgery, Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, Texas., Sheehan V; Department of Pediatrics, Section of Hematology-Oncology, Texas Children's Cancer and Hematology Centers, Baylor College of Medicine, Houston, Texas., Kim ES; Division of Pediatric Surgery, Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, Texas., Paust S; Department of Pediatrics, Center for Human Immunobiology, Texas Children's Hospital, Baylor College of Medicine, Houston, Texas., Shohet JM; Department of Pediatrics, Section of Hematology-Oncology, Texas Children's Cancer and Hematology Centers, Baylor College of Medicine, Houston, Texas., Barbieri E; Department of Pediatrics, Section of Hematology-Oncology, Texas Children's Cancer and Hematology Centers, Baylor College of Medicine, Houston, Texas. exbarbie@txch.org.

المصدر: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2017 Nov 01; Vol. 23 (21), pp. 6629-6639. Date of Electronic Publication: 2017 Aug 18.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: The Association Country of Publication: United States NLM ID: 9502500 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1557-3265 (Electronic) Linking ISSN: 10780432 NLM ISO Abbreviation: Clin Cancer Res Subsets: MEDLINE

مواضيع طبية MeSH: Neuroblastoma/*drug therapy , Proto-Oncogene Proteins c-mdm2/*genetics , TOR Serine-Threonine Kinases/*genetics , Tumor Suppressor Protein p53/*genetics, Animals ; Antineoplastic Combined Chemotherapy Protocols/administration & dosage ; Apoptosis/drug effects ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Drug Resistance, Neoplasm/genetics ; Gene Expression Regulation, Neoplastic/drug effects ; Humans ; Mechanistic Target of Rapamycin Complex 1/antagonists & inhibitors ; Mice ; Neuroblastoma/genetics ; Neuroblastoma/pathology ; Proto-Oncogene Proteins c-mdm2/antagonists & inhibitors ; Pyrrolidines/administration & dosage ; Sirolimus/administration & dosage ; Sirolimus/analogs & derivatives ; TOR Serine-Threonine Kinases/antagonists & inhibitors ; Xenograft Model Antitumor Assays ; para-Aminobenzoates/administration & dosage

المؤلفون: Du M; Department of Pediatrics, Section of Hematology-Oncology, Texas Children's Cancer and Hematology Centers, Baylor College of Medicine, Houston, TX 77030, USA., Zhang L; Department of Pediatrics, Section of Hematology-Oncology, Texas Children's Cancer and Hematology Centers, Baylor College of Medicine, Houston, TX 77030, USA., Scorsone KA; Department of Pediatrics, Section of Hematology-Oncology, Texas Children's Cancer and Hematology Centers, Baylor College of Medicine, Houston, TX 77030, USA., Woodfield SE; Department of Pediatrics, Section of Hematology-Oncology, Texas Children's Cancer and Hematology Centers, Baylor College of Medicine, Houston, TX 77030, USA., Zage PE; Department of Pediatrics, Section of Hematology-Oncology, Texas Children's Cancer and Hematology Centers, Baylor College of Medicine, Houston, TX 77030, USA.

المصدر: Scientific reports [Sci Rep] 2016 Jun 10; Vol. 6, pp. 27458. Date of Electronic Publication: 2016 Jun 10.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

مواضيع طبية MeSH: Buthionine Sulfoximine/*pharmacology , Neuroblastoma/*drug therapy , Nifurtimox/*pharmacology, Apoptosis/drug effects ; Cell Line, Tumor ; Cell Survival/drug effects ; Drug Synergism ; Humans ; Phosphorylation/drug effects ; Signal Transduction/drug effects

المؤلفون: Woodfield SE; Department of Pediatrics, Section of Hematology-Oncology, Baylor College of Medicine, Houston, TX, USA. woodfiel@bcm.edu., Zhang L; Department of Pediatrics, Section of Hematology-Oncology, Baylor College of Medicine, Houston, TX, USA. lxzhang@txch.org., Scorsone KA; Department of Pediatrics, Section of Hematology-Oncology, Baylor College of Medicine, Houston, TX, USA. kascorso@txch.org., Liu Y; Department of Neurobiology and Anatomy, The University of Texas Medical School, Houston, TX, USA. yin.liu@uth.tmc.edu.; Department of Biomedical Engineering, University of Texas at Austin, Austin, TX, USA. yin.liu@uth.tmc.edu., Zage PE; Department of Pediatrics, Section of Hematology-Oncology, Baylor College of Medicine, Houston, TX, USA. zage@bcm.edu.; Texas Children's Cancer Center, Houston, TX, USA. zage@bcm.edu.

المصدر: BMC cancer [BMC Cancer] 2016 Mar 01; Vol. 16, pp. 172. Date of Electronic Publication: 2016 Mar 01.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 100967800 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2407 (Electronic) Linking ISSN: 14712407 NLM ISO Abbreviation: BMC Cancer Subsets: MEDLINE

مواضيع طبية MeSH: Gene Expression Regulation, Neoplastic*, Benzimidazoles/*pharmacology , Extracellular Signal-Regulated MAP Kinases/*antagonists & inhibitors , Neuroblastoma/*genetics , Neuroblastoma/*metabolism , Neurofibromin 1/*genetics , Protein Kinase Inhibitors/*pharmacology, Cell Line, Tumor ; Dose-Response Relationship, Drug ; Humans ; Neurofibromin 1/metabolism ; Signal Transduction/drug effects ; ras Proteins/metabolism

المؤلفون: Ryu RJ; Department of Pharmacy, University of Washington, 1959 NE Pacific Street, H-375 Health Sciences Center, Box 357630, Seattle, WA, 98195-7630, USA., Eyal S, Kaplan HG, Akbarzadeh A, Hays K, Puhl K, Easterling TR, Berg SL, Scorsone KA, Feldman EM, Umans JG, Miodovnik M, Hebert MF

المصدر: Cancer chemotherapy and pharmacology [Cancer Chemother Pharmacol] 2014 Apr; Vol. 73 (4), pp. 789-97. Date of Electronic Publication: 2014 Feb 15.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 7806519 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-0843 (Electronic) Linking ISSN: 03445704 NLM ISO Abbreviation: Cancer Chemother Pharmacol Subsets: MEDLINE

مواضيع طبية MeSH: Antibiotics, Antineoplastic/*pharmacokinetics , Doxorubicin/*pharmacokinetics , Neoplasms/*drug therapy , Neoplasms/*metabolism , Pregnancy Complications, Neoplastic/*drug therapy , Pregnancy Complications, Neoplastic/*metabolism, Administration, Intravenous ; Adult ; Antibiotics, Antineoplastic/administration & dosage ; Antibiotics, Antineoplastic/blood ; Antibiotics, Antineoplastic/urine ; Doxorubicin/administration & dosage ; Doxorubicin/blood ; Doxorubicin/urine ; Female ; Humans ; Middle Aged ; Neoplasms/blood ; Neoplasms/urine ; Pregnancy ; Pregnancy Complications, Neoplastic/blood ; Pregnancy Complications, Neoplastic/urine ; Young Adult

المؤلفون: Muscal JA; Texas Children's Cancer Center, Baylor College of Medicine, 1102 Bates Street, Suite 1220, Houston, TX 77030, USA. jamuscal@txch.org, Scorsone KA, Zhang L, Ecsedy JA, Berg SL

المصدر: Investigational new drugs [Invest New Drugs] 2013 Feb; Vol. 31 (1), pp. 39-45. Date of Electronic Publication: 2012 Jun 06.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Springer Country of Publication: United States NLM ID: 8309330 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-0646 (Electronic) Linking ISSN: 01676997 NLM ISO Abbreviation: Invest New Drugs Subsets: MEDLINE

مواضيع طبية MeSH: Antineoplastic Agents/*administration & dosage , Azepines/*administration & dosage , Histone Deacetylase Inhibitors/*administration & dosage , Hydroxamic Acids/*administration & dosage , Protein Kinase Inhibitors/*administration & dosage , Protein Serine-Threonine Kinases/*antagonists & inhibitors , Pyrimidines/*administration & dosage, Aurora Kinase B ; Aurora Kinases ; Cell Line, Tumor ; Cell Survival/drug effects ; Drug Interactions ; Humans ; Leukemia/drug therapy ; Leukemia/enzymology ; Medulloblastoma/drug therapy ; Medulloblastoma/enzymology ; Neuroblastoma/drug therapy ; Neuroblastoma/enzymology ; Protein Serine-Threonine Kinases/metabolism ; Vorinostat

المؤلفون: Colbert RA; E. Henry Keutmann Laboratories, Department of Medicine, Rochester, New York., Hucul JA, Scorsone KA, Young DA

المصدر: The Journal of biological chemistry [J Biol Chem] 1987 Dec 15; Vol. 262 (35), pp. 16763-6.

نوع المنشور: Journal Article; Research Support, U.S. Gov't, P.H.S.

بيانات الدورية: Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication Model: Print Cited Medium: Print ISSN: 0021-9258 (Print) Linking ISSN: 00219258 NLM ISO Abbreviation: J Biol Chem Subsets: MEDLINE

مواضيع طبية MeSH: Heat-Shock Proteins/*analysis , Peptide Initiation Factors/*analysis , Proteins/*analysis, Animals ; Antibodies, Monoclonal ; Electrophoresis, Polyacrylamide Gel/methods ; Eukaryotic Initiation Factor-2 ; Male ; Methionine/metabolism ; Rats ; Rats, Inbred Strains ; T-Lymphocytes/analysis