المؤلفون: Kenneth M. Comess, Steven Kennedy, Donald J. Osterling, Michael L. Curtin, Masoud Vedadi, Ramzi F. Sweis, Guillermo Senisterra, Mikkel Algire, Evelyne Lima-Fernandes, Dalia Barsyte-Lovejoy, Justin D. Dietrich, William N. Pappano, Bailin Shaw, David Maag, Dong Cheng, Cheryl H. Arrowsmith, Fengling Li, Marina A. Pliushchev, Kelly L Klinge, Jun Guo, Chaohong Sun, Andrew M. Petros, Gary G. Chiang, Magdalena M. Szewczyk, Huan-Qiu Li, Maricel Torrent, Scott Galasinski, Sujatha Selvaraju, Yupeng He, David Lindley, Clarissa G. Jakob, Sanjay C. Panchal, Wenqing Gao, Lance J Bigelow, Haizhong Zhu, Fritz G. Buchanan, Qin Wu

المصدر: Nature chemical biology. 13(4)

مصطلحات موضوعية: 0301 basic medicine, Models, Molecular, Cell Survival, Protein subunit, Allosteric regulation, Antineoplastic Agents, macromolecular substances, Protein–protein interaction, 03 medical and health sciences, Histone H3, Structure-Activity Relationship, 0302 clinical medicine, Cell Line, Tumor, Tumor Cells, Cultured, Gene silencing, Humans, Epigenetics, Molecular Biology, Cell Proliferation, chemistry.chemical_classification, Sulfonamides, biology, Dose-Response Relationship, Drug, Molecular Structure, Polycomb Repressive Complex 2, Cell Biology, 030104 developmental biology, Enzyme, Biochemistry, chemistry, 030220 oncology & carcinogenesis, Indans, biology.protein, Drug Screening Assays, Antitumor, PRC2, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4df1801f71a6c72b86efbe30951bf648
https://pubmed.ncbi.nlm.nih.gov/28853738

المؤلفون: Jennifer L. Miller, Steve Birkos, William P. Janzen, Paul Steed, Scott Galasinski, Lynn A. Cheatham, C. N. Hodge, Jennifer Clark, Ioana Popa-Burke, John K. Dickson, Robert P. Mohney, Jose Serafin Mendoza, Leonard J. Blackwell

المصدر: Current Topics in Medicinal Chemistry. 5:941-951

مصطلحات موضوعية: chemistry.chemical_classification, Proteases, Kinase, p38 mitogen-activated protein kinases, Phosphatase, Druggability, General Medicine, Biology, Serine, Enzyme, Mechanism of action, chemistry, Biochemistry, Drug Discovery, medicine, medicine.symptom

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::04014fa6218fe0bfada6b5a7bf3be74c
https://doi.org/10.2174/1568026054985867

المؤلفون: Nikolai F. Sepetov, James D. Arroway, Olga Issakova, Dennis Lagasca, Ajit Jadhav, Min Chen, Ioana Popa-Burke, Paul Bernasconi, Scott Galasinski, Robert P. Mohney, Darren A. Sparkman, Roderic S. Lewis, Louis Coudurier, Darren Liu, William P. Janzen, C. Nicholas Hodge

المصدر: Analytical Chemistry. 76:7278-7287

مصطلحات موضوعية: Libraries, Concentration effect, Ligands, Mass Spectrometry, Analytical Chemistry, Inhibitory Concentration 50, Chromatography detector, Spectrophotometry, medicine, Combinatorial Chemistry Techniques, Bioassay, Dimethyl Sulfoxide, Solubility, Chromatography, High Pressure Liquid, Detection limit, Chromatography, medicine.diagnostic_test, Chemistry, Drug discovery, Proteins, Pharmaceutical Preparations, Biological target, Biological Assay, Spectrophotometry, Ultraviolet, Chromatography, Liquid

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db5b3d284d231f4c3b9f70568276a136
https://doi.org/10.1021/ac0491859

المؤلفون: Yupeng, He, Sujatha, Selvaraju, Michael L, Curtin, Clarissa G, Jakob, Haizhong, Zhu, Kenneth M, Comess, Bailin, Shaw, Juliana, The, Evelyne, Lima-Fernandes, Magdalena M, Szewczyk, Dong, Cheng, Kelly L, Klinge, Huan-Qiu, Li, Marina, Pliushchev, Mikkel A, Algire, David, Maag, Jun, Guo, Justin, Dietrich, Sanjay C, Panchal, Andrew M, Petros, Ramzi F, Sweis, Maricel, Torrent, Lance J, Bigelow, Guillermo, Senisterra, Fengling, Li, Steven, Kennedy, Qin, Wu, Donald J, Osterling, David J, Lindley, Wenqing, Gao, Scott, Galasinski, Dalia, Barsyte-Lovejoy, Masoud, Vedadi, Fritz G, Buchanan, Cheryl H, Arrowsmith, Gary G, Chiang, Chaohong, Sun, William N, Pappano

المصدر: Nature Chemical Biology. 13:922-922

مصطلحات موضوعية: Cell Biology, Molecular Biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e1ad2ca8539d282b5c2077653a358e6
https://doi.org/10.1038/nchembio0817-922b

المؤلفون: Kenneth M. Comess, Vivek C. Abraham, Philip J. Hajduk, Danli L. Towne, Emily E. Nicholl, Scott Galasinski

المصدر: Journal of biomolecular screening. 17(8)

مصطلحات موضوعية: Oncology, medicine.medical_specialty, Antineoplastic Agents, Apoptosis, Biology, Biochemistry, Analytical Chemistry, Internal medicine, Cell Line, Tumor, Drug Discovery, medicine, Image Processing, Computer-Assisted, Humans, Cell Proliferation, Dose-Response Relationship, Drug, Drug discovery, Cell Cycle, Screening assay, Cytochromes c, Automated microscopy, Cell cycle, High-Throughput Screening Assays, Mitochondria, Mechanism of action, Microscopy, Fluorescence, High-content screening, Molecular Medicine, Target protein, medicine.symptom, Drug Screening Assays, Antitumor, Biotechnology, DNA Damage

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf8fe600d73af3de52a2ec536dc43837
https://pubmed.ncbi.nlm.nih.gov/22706350

المؤلفون: Stevan W. Djuric, Irini Akritopoulou-Zanze, Scott Galasinski, Philip B. Cox

مصطلحات موضوعية: Lead (geology), business.industry, Bioactive molecules, High-throughput screening, Druggability, Medicine, Nanotechnology, business, Data science

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::b02e8a92818018cd91976fda55906752
https://doi.org/10.1016/s0065-7743(10)45025-3

المؤلفون: Scott Galasinski, William P. Janzen, Rhonda Hallam, Ioana Popa-Burke, Louis Coudurier, Paul Bernasconi, Min Chen, Anna Bobasheva, Steve Birkos

المصدر: Journal of biomolecular screening. 12(7)

مصطلحات موضوعية: 0301 basic medicine, Proteome, Computational biology, Biology, 01 natural sciences, Biochemistry, Analytical Chemistry, 03 medical and health sciences, Phylogenetics, Human proteome project, Humans, Enzyme Inhibitors, Phylogeny, Genetics, chemistry.chemical_classification, Drug discovery, Genomics, 0104 chemical sciences, Enzymes, 010404 medicinal & biomolecular chemistry, 030104 developmental biology, Sequence homology, Enzyme, Distance matrix, chemistry, Molecular Medicine, Orthogonal method, Biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::579aacf0e229a81642f1cae22de57a75
https://pubmed.ncbi.nlm.nih.gov/17942790

المؤلفون: Scott Galasinski, Arnold Hampel, Mary Beth De Young, Andrew Siwkowski

مصطلحات موضوعية: Small hairpin RNA, biology, Stereochemistry, Chemistry, Ribozyme, biology.protein, Mammalian CPEB3 ribozyme, Stem-loop, Hairpin ribozyme, Tetraloop, VS ribozyme, Ligase ribozyme

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::2608cc971bce82956caf96addbc5c04a
https://doi.org/10.1385/0-89603-389-9:171