نتائج البحث - "Scott Haston"

المصدر: Carreno, G, Apps, J R, Lodge, E J, Panousopoulos, L, Haston, S, Gonzalez-Meljem, J M, Hahn, H, Andoniadou, C L & Martinez-Barbera, J P 2017, ' Hypothalamic sonic hedgehog is required for cell specification and proliferation of LHX3/LHX4 pituitary embryonic precursors ', Development, vol. 144, no. 18, pp. 3289-3302 . https://doi.org/10.1242/dev.153387

مصطلحات موضوعية: 0301 basic medicine, Male, Cell, Cell Count, Epithelium, 0302 clinical medicine, Sonic hedgehog, 0303 health sciences, biology, Stem Cells, Endoderm, Gene Expression Regulation, Developmental, Cell Differentiation, Cell biology, medicine.anatomical_structure, Pituitary Gland, embryonic structures, Female, LHX3, Research Article, Signal Transduction, Patched, animal structures, Genotype, LIM-Homeodomain Proteins, Hypothalamus, Cell fate determination, 03 medical and health sciences, SOX2, Ectoderm, Journal Article, medicine, Humans, Cell Lineage, Hedgehog Proteins, Progenitor cell, Molecular Biology, Crosses, Genetic, Progenitor, Cell Proliferation, 030304 developmental biology, Embryo, Mammalian, Embryonic stem cell, Cell Compartmentation, Clone Cells, 030104 developmental biology, Mutation, Cancer research, biology.protein, 030217 neurology & neurosurgery, Developmental Biology, Transcription Factors

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8fe6078a027663abb7f538cbd202043
https://doi.org/10.1530/ey.15.1.6

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Tumour compartment transcriptomics demonstrates the activation of inflammatory and odontogenic programmes in human adamantinomatous craniopharyngioma and identifies the MAPK/ERK pathway as a novel therapeutic target

المصدر: Apps, J R, Carreno, G, Gonzalez-meljem, J M, Haston, S, Guiho, R, Cooper, J E, Manshaei, S, Jani, N, Hölsken, A, Pettorini, B, Beynon, R J, Simpson, D M, Fraser, H C, Hong, Y, Hallang, S, Stone, T J, Virasami, A, Donson, A M, Jones, D, Aquilina, K, Spoudeas, H, Joshi, A R, Grundy, R, Storer, L C D, Korbonits, M, Hilton, D A, Tossell, K, Thavaraj, S, Ungless, M A, Gil, J, Buslei, R, Hankinson, T, Hargrave, D, Goding, C, Andoniadou, C L, Brogan, P, Jacques, T S, Williams, H J & Martinez-Barbera, J P 2018, ' Tumour compartment transcriptomics demonstrates the activation of inflammatory and odontogenic programmes in human adamantinomatous craniopharyngioma and identifies the MAPK/ERK pathway as a novel therapeutic target ', Acta Neuropathologica, vol. 135, no. 5, pp. 757-777 . https://doi.org/10.1007/s00401-018-1830-2
Acta Neuropathologica

مصطلحات موضوعية: 0301 basic medicine, MAPK/ERK pathway, medicine.medical_treatment, PATHOGENESIS, Stem cell marker, BETA-CATENIN, Inflammasome, Tissue Culture Techniques, Mice, Craniopharyngioma, 0302 clinical medicine, MOUSE MODELS, Tumor Microenvironment, Pathology, INTERLEUKIN-1, TOOTH FORMATION, Laser capture microdissection, MEK inhibitor, 3. Good health, Cytokine, DIFFERENTIATION, Pituitary Gland, Paracrine signalling, Cytokines, Odontogenesis, IL1-β, Neuroglia, Life Sciences & Biomedicine, EXPRESSION, Cell type, MAP Kinase Signaling System, Clinical Neurology, Laser Capture Microdissection, Biology, Pathology and Forensic Medicine, 03 medical and health sciences, Cellular and Molecular Neuroscience, stomatognathic system, Trametinib, medicine, Animals, Humans, Pituitary Neoplasms, Inflammation, Original Paper, Science & Technology, Neurology & Neurosurgery, Sequence Analysis, RNA, Neurosciences, Computational Biology, 1103 Clinical Sciences, Disease Models, Animal, 030104 developmental biology, PAPILLARY CRANIOPHARYNGIOMAS, CELLS, MORPHOGENESIS, Cancer research, Neurology (clinical), Neurosciences & Neurology, Transcriptome, 1109 Neurosciences, 030217 neurology & neurosurgery, Immunostaining, IL1-beta