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المؤلفون: Ingo Muegge, Scott Oloff
المصدر: Burger's Medicinal Chemistry and Drug Discovery. :1-46
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::fe8ba16001783feb9f589e734bebcfe7
https://doi.org/10.1002/0471266949.bmc006.pub2 -
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المؤلفون: Ingo Muegge, Scott Oloff
المصدر: Journal of Computer-Aided Molecular Design. 21:87-95
مصطلحات موضوعية: Artificial neural network, business.industry, Computer science, Quantitative Structure-Activity Relationship, Pattern recognition, Models, Theoretical, Machine learning, computer.software_genre, Data structure, Computer Science Applications, Support vector machine, symbols.namesake, Naive Bayes classifier, Artificial Intelligence, Drug Design, Kernel (statistics), Drug Discovery, symbols, Structural risk minimization, Artificial intelligence, Physical and Theoretical Chemistry, business, Gaussian process, computer, Applicability domain
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المؤلفون: Scott Oloff, William A. Goddard, Adam R. Griffith, Richard B. Mailman, Jessica P. Ryman-Rasmussen, Justin T. Brown, Nagarajan Vaidehi
المصدر: Neuropharmacology. 52:562-575
مصطلحات موضوعية: Models, Molecular, Receptor recycling, Time Factors, Dopamine, Dinapsoline, Adamantane, Naphthols, Article, 5-HT7 receptor, Radioligand Assay, Cellular and Molecular Neuroscience, Methionine, Dopamine receptor D1, Dopamine receptor D2, Sulfur Isotopes, Functional selectivity, Enzyme-linked receptor, Humans, Benzopyrans, Drug Interactions, Protease-activated receptor 2, Cell Line, Transformed, Pharmacology, Microscopy, Confocal, Dose-Response Relationship, Drug, Chemistry, Receptors, Dopamine D1, Benzazepines, Isoquinolines, Cell biology, Protein Transport, Biochemistry, Dopamine Agonists, Dopamine Antagonists, Protein Binding
وصف الملف: application/pdf
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المؤلفون: Ingo Muegge, Scott Oloff
المصدر: Drug Discovery Today. Technologies
مصطلحات موضوعية: Virtual screening, Identification (information), Lead (geology), business.industry, Computer science, In silico, Drug Discovery, Molecular Medicine, Nanotechnology, business, Data science, Article, Pharmaceutical industry
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المؤلفون: Alexander Tropsha, Rafael Castillo, Alexander Golbraikh, José L. Medina-Franco, Scott Oloff
المصدر: Journal of Computer-Aided Molecular Design. 19:229-242
مصطلحات موضوعية: Models, Molecular, Quantitative structure–activity relationship, Nevirapine, Database, Pyridones, Human immunodeficiency virus (HIV), Quantitative Structure-Activity Relationship, Feature selection, AutoDock, computer.software_genre, medicine.disease_cause, HIV Reverse Transcriptase, Reverse transcriptase, Computer Science Applications, k-nearest neighbors algorithm, Docking (molecular), Drug Discovery, medicine, Database Management Systems, Reverse Transcriptase Inhibitors, Physical and Theoretical Chemistry, computer, medicine.drug, Mathematics
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المؤلفون: J. Feng, Alexander Golbraikh, Alexander Tropsha, W. Zheng, Scott Oloff, Assia Kovatcheva
المصدر: SAR and QSAR in Environmental Research. 16:93-102
مصطلحات موضوعية: Quantitative structure–activity relationship, Molecular Conformation, Quantitative Structure-Activity Relationship, Ambergris, Bioengineering, Stereoisomerism, Cyclopentanes, Models, Biological, k-nearest neighbors algorithm, Partial charge, Predictive Value of Tests, Computational chemistry, Molecular descriptor, Drug Discovery, Combinatorial Chemistry Techniques, Chemistry, Ecdysteroids, General Medicine, Santalum, Test set, Odorants, Molecular Medicine, Biological system, Chirality (chemistry)
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المؤلفون: Scott Oloff, Lemont B. Kier, Marc Parham, Weida Tong, Joseph R. Votano, Lowell H. Hall, Alexander Tropsha, Qian Xie
المصدر: Mutagenesis. 19:365-377
مصطلحات موضوعية: Salmonella typhimurium, Quantitative structure–activity relationship, Health, Toxicology and Mutagenesis, Concordance, Quantitative Structure-Activity Relationship, Toxicology, medicine.disease_cause, Sensitivity and Specificity, Structure-Activity Relationship, Reliability criterion, Statistics, Genetics, medicine, Model development, Genetics (clinical), Mathematics, Mutagenicity Tests, External validation, Models, Theoretical, Random forest, Databases as Topic, Models, Chemical, Pharmaceutical Preparations, Neural Networks, Computer, Algorithms, Software, Genotoxicity, DNA Damage, Mutagens
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::138374029c991be976db5a825595e6bd
https://doi.org/10.1093/mutage/geh043 -
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المؤلفون: Wolfgang J. Nett, Scott Oloff, Ken D. McCarthy
المصدر: Journal of Neurophysiology. 87:528-537
مصطلحات موضوعية: Intracellular Fluid, In situ, Indoles, Patch-Clamp Techniques, Purinergic Antagonists, Physiology, Hippocampus, chemistry.chemical_element, Tetrodotoxin, In Vitro Techniques, Hippocampal formation, Calcium, Receptors, Metabotropic Glutamate, Mice, chemistry.chemical_compound, Biological Clocks, Excitatory Amino Acid Agonists, Animals, Premovement neuronal activity, Calcium Signaling, Patch clamp, Enzyme Inhibitors, Fluorescent Dyes, Calcium signaling, Neurons, Heparin, Chemistry, Pyramidal Cells, General Neuroscience, Calcium-Binding Proteins, Microfilament Proteins, Anti-Bacterial Agents, DNA-Binding Proteins, Purinergic Agonists, Astrocytes, Biophysics, Cell Surface Extensions, Macrolides, Excitatory Amino Acid Antagonists, Neuroscience
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::809bae590db30f9c96aab79d0ff6e4d3
https://doi.org/10.1152/jn.00268.2001 -
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المؤلفون: Lowell H. Hall, L. Mark Hall, Marc Parham, Scott Oloff, Lemont B. Kier, Joseph R. Votano, Alexander Tropsha
المصدر: Journal of medicinal chemistry. 49(24)
مصطلحات موضوعية: Models, Molecular, Quantitative structure–activity relationship, business.industry, Chemistry, Linear model, Quantitative Structure-Activity Relationship, Pattern recognition, Blood Proteins, Data set, Support vector machine, Set (abstract data type), Pharmaceutical Preparations, Test set, Drug Design, Drug Discovery, Linear regression, Linear Models, Molecular Medicine, Humans, Artificial intelligence, Neural Networks, Computer, Cluster analysis, business, Protein Binding
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المصدر: ChemInform. 37
مصطلحات موضوعية: Models, Molecular, Quantitative structure–activity relationship, General Chemical Engineering, Decision tree, Quantitative Structure-Activity Relationship, Library and Information Sciences, Machine learning, computer.software_genre, Model validation, Modelling methods, Molecular descriptor, Combinatorial Chemistry Techniques, ATP Binding Cassette Transporter, Subfamily B, Member 1, business.industry, Chemistry, Decision Trees, General Chemistry, General Medicine, Computer Science Applications, Support vector machine, Optimization methods, Artificial intelligence, business, Biological system, computer, Protein Binding