المؤلفون: Tucker JB; Cancer Biology Graduate Training Program, University of Wisconsin-Madison, Madison, Wisconsin., Carlsen CL; Cellular and Molecular Biology Graduate Training Program, University of Wisconsin-Madison, Madison, Wisconsin., Scribano CM; Cellular and Molecular Pharmacology Graduate Training Program, University of Wisconsin-Madison, Madison, Wisconsin., Pattaswamy SM; Department of Cell and Regenerative Biology, University of Wisconsin-Madison, Madison, Wisconsin., Burkard ME; Department of Oncology, McArdle Laboratory for Cancer Research, University of Wisconsin-Madison, Madison, Wisconsin.; Department of Medicine, University of Wisconsin-Madison, Madison, Wisconsin.; Carbone Cancer Center, University of Wisconsin-Madison, Madison, Wisconsin., Weaver BA; Department of Cell and Regenerative Biology, University of Wisconsin-Madison, Madison, Wisconsin.; Department of Oncology, McArdle Laboratory for Cancer Research, University of Wisconsin-Madison, Madison, Wisconsin.; Carbone Cancer Center, University of Wisconsin-Madison, Madison, Wisconsin.

المصدر: Cancer research [Cancer Res] 2024 Aug 15; Vol. 84 (16), pp. 2674-2689.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 2984705R Publication Model: Print Cited Medium: Internet ISSN: 1538-7445 (Electronic) Linking ISSN: 00085472 NLM ISO Abbreviation: Cancer Res Subsets: MEDLINE

مواضيع طبية MeSH: Chromosomal Instability*/drug effects , Breast Neoplasms*/pathology , Breast Neoplasms*/drug therapy , Breast Neoplasms*/genetics , Breast Neoplasms*/metabolism , Chromosomal Proteins, Non-Histone*/metabolism , Chromosomal Proteins, Non-Histone*/genetics , Microtubules*/drug effects , Microtubules*/metabolism , Drug Synergism*, Humans ; Female ; Animals ; Mice ; Cell Line, Tumor ; Spindle Apparatus/drug effects ; Spindle Apparatus/metabolism ; Xenograft Model Antitumor Assays ; Mitosis/drug effects ; Antineoplastic Agents/pharmacology

المؤلفون: Smith JT; Elephas, Madison, Wisconsin, United States.; Booz Allen Hamilton, McLean, Virginia, United States., Liu CJ; Elephas, Madison, Wisconsin, United States., Degnan J; Elephas, Madison, Wisconsin, United States., Ouellette JN; Elephas, Madison, Wisconsin, United States., Conklin MW; Elephas, Madison, Wisconsin, United States., Kellner AV; Elephas, Madison, Wisconsin, United States., Scribano CM; Elephas, Madison, Wisconsin, United States., Hrycyniak L; Elephas, Madison, Wisconsin, United States., Oliner JD; Elephas, Madison, Wisconsin, United States., Zahm C; Elephas, Madison, Wisconsin, United States., Wait E; Elephas, Madison, Wisconsin, United States., Eliceiri KW; Center for Quantitative Cell Imaging, Madison, Wisconsin, United States., Rafter J; Elephas, Madison, Wisconsin, United States.

المصدر: Journal of biomedical optics [J Biomed Opt] 2024 Jun; Vol. 29 (Suppl 2), pp. S22709. Date of Electronic Publication: 2024 Jun 14.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Published by SPIE--the International Society for Optical Engineering in cooperation with International Biomedical Optics Society Country of Publication: United States NLM ID: 9605853 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1560-2281 (Electronic) Linking ISSN: 10833668 NLM ISO Abbreviation: J Biomed Opt Subsets: MEDLINE

مواضيع طبية MeSH: Cell Survival*/drug effects , Microscopy, Fluorescence, Multiphoton*/methods, Animals ; Mice ; Apoptosis ; Flavin-Adenine Dinucleotide/chemistry ; NADP/metabolism ; Cell Line, Tumor ; Optical Imaging/methods

المؤلفون: Zhou AS; Molecular and Cellular Pharmacology Graduate Training Program, University of Wisconsin, Madison, Wisconsin, United States of America., Tucker JB; Cancer Biology Graduate Training Program, University of Wisconsin, Madison, Wisconsin, United States of America., Scribano CM; Molecular and Cellular Pharmacology Graduate Training Program, University of Wisconsin, Madison, Wisconsin, United States of America., Lynch AR; Cellular and Molecular Pathology Graduate Training Program, University of Wisconsin, Madison, Wisconsin, United States of America., Carlsen CL; Cellular and Molecular Biology Graduate Training Program, University of Wisconsin, Madison, Wisconsin, United States of America., Pop-Vicas ST; Department of Cell and Regenerative Biology, University of Wisconsin, Madison, Wisconsin, United States of America., Pattaswamy SM; Department of Cell and Regenerative Biology, University of Wisconsin, Madison, Wisconsin, United States of America., Burkard ME; Department of Medicine, University of Wisconsin, Madison, Wisconsin, United States of America.; Department of Oncology/McArdle Laboratory for Cancer Research, University of Wisconsin, Madison, Wisconsin, United States of America.; Carbone Cancer Center, University of Wisconsin, Madison, Wisconsin, United States of America., Weaver BA; Department of Cell and Regenerative Biology, University of Wisconsin, Madison, Wisconsin, United States of America.; Department of Oncology/McArdle Laboratory for Cancer Research, University of Wisconsin, Madison, Wisconsin, United States of America.; Carbone Cancer Center, University of Wisconsin, Madison, Wisconsin, United States of America.

المصدر: PLoS biology [PLoS Biol] 2023 Oct 26; Vol. 21 (10), pp. e3002339. Date of Electronic Publication: 2023 Oct 26 (Print Publication: 2023).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101183755 Publication Model: eCollection Cited Medium: Internet ISSN: 1545-7885 (Electronic) Linking ISSN: 15449173 NLM ISO Abbreviation: PLoS Biol Subsets: MEDLINE

مواضيع طبية MeSH: Antineoplastic Agents*/pharmacology , Poisons*/metabolism, Humans ; Microtubules/metabolism ; Spindle Apparatus ; Mitosis ; Kinetochores

المؤلفون: Hu Y; Department of Medicine, Hematology/Oncology, University of Wisconsin-Madison, Madison, Wisconsin.; McArdle Laboratory for Cancer Research, University of Wisconsin-Madison, Madison, Wisconsin.; UW Carbone Cancer Center, University of Wisconsin-Madison, Madison, Wisconsin.; Medical Scientist Training Program, University of Wisconsin-Madison, Madison, Wisconsin., Manasrah BK; Department of Medicine, Hematology/Oncology, University of Wisconsin-Madison, Madison, Wisconsin.; McArdle Laboratory for Cancer Research, University of Wisconsin-Madison, Madison, Wisconsin.; UW Carbone Cancer Center, University of Wisconsin-Madison, Madison, Wisconsin., McGregor SM; UW Carbone Cancer Center, University of Wisconsin-Madison, Madison, Wisconsin.; Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, Wisconsin., Lera RF; Department of Medicine, Hematology/Oncology, University of Wisconsin-Madison, Madison, Wisconsin.; McArdle Laboratory for Cancer Research, University of Wisconsin-Madison, Madison, Wisconsin.; UW Carbone Cancer Center, University of Wisconsin-Madison, Madison, Wisconsin., Norman RX; Department of Medicine, Hematology/Oncology, University of Wisconsin-Madison, Madison, Wisconsin.; McArdle Laboratory for Cancer Research, University of Wisconsin-Madison, Madison, Wisconsin.; UW Carbone Cancer Center, University of Wisconsin-Madison, Madison, Wisconsin., Tucker JB; McArdle Laboratory for Cancer Research, University of Wisconsin-Madison, Madison, Wisconsin.; UW Carbone Cancer Center, University of Wisconsin-Madison, Madison, Wisconsin.; Department of Cell and Regenerative Biology, University of Wisconsin-Madison, Madison, Wisconsin., Scribano CM; McArdle Laboratory for Cancer Research, University of Wisconsin-Madison, Madison, Wisconsin.; UW Carbone Cancer Center, University of Wisconsin-Madison, Madison, Wisconsin.; Department of Cell and Regenerative Biology, University of Wisconsin-Madison, Madison, Wisconsin., Yan RE; Department of Medicine, Hematology/Oncology, University of Wisconsin-Madison, Madison, Wisconsin.; McArdle Laboratory for Cancer Research, University of Wisconsin-Madison, Madison, Wisconsin.; UW Carbone Cancer Center, University of Wisconsin-Madison, Madison, Wisconsin., Humayun M; UW Carbone Cancer Center, University of Wisconsin-Madison, Madison, Wisconsin.; Department of Biomedical Engineering, University of Wisconsin-Madison, Madison, Wisconsin., Wisinski KB; Department of Medicine, Hematology/Oncology, University of Wisconsin-Madison, Madison, Wisconsin.; UW Carbone Cancer Center, University of Wisconsin-Madison, Madison, Wisconsin., Tevaarwerk AJ; Department of Medicine, Hematology/Oncology, University of Wisconsin-Madison, Madison, Wisconsin.; UW Carbone Cancer Center, University of Wisconsin-Madison, Madison, Wisconsin., O'Regan RM; Department of Medicine, Hematology/Oncology, University of Wisconsin-Madison, Madison, Wisconsin.; UW Carbone Cancer Center, University of Wisconsin-Madison, Madison, Wisconsin., Wilke LG; UW Carbone Cancer Center, University of Wisconsin-Madison, Madison, Wisconsin.; Department of Surgery, University of Wisconsin-Madison, Madison, Wisconsin., Weaver BA; McArdle Laboratory for Cancer Research, University of Wisconsin-Madison, Madison, Wisconsin.; UW Carbone Cancer Center, University of Wisconsin-Madison, Madison, Wisconsin.; Department of Cell and Regenerative Biology, University of Wisconsin-Madison, Madison, Wisconsin., Beebe DJ; UW Carbone Cancer Center, University of Wisconsin-Madison, Madison, Wisconsin.; Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, Wisconsin.; Department of Biomedical Engineering, University of Wisconsin-Madison, Madison, Wisconsin., Jin N; Department of Medicine, Hematology/Oncology, University of Wisconsin-Madison, Madison, Wisconsin. mburkard@wisc.edu ning.jin2@osumc.edu.; UW Carbone Cancer Center, University of Wisconsin-Madison, Madison, Wisconsin., Burkard ME; Department of Medicine, Hematology/Oncology, University of Wisconsin-Madison, Madison, Wisconsin. mburkard@wisc.edu ning.jin2@osumc.edu.; McArdle Laboratory for Cancer Research, University of Wisconsin-Madison, Madison, Wisconsin.; UW Carbone Cancer Center, University of Wisconsin-Madison, Madison, Wisconsin.

المصدر: Molecular cancer therapeutics [Mol Cancer Ther] 2021 Dec; Vol. 20 (12), pp. 2553-2567. Date of Electronic Publication: 2021 Sep 28.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Association for Cancer Research, Inc Country of Publication: United States NLM ID: 101132535 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1538-8514 (Electronic) Linking ISSN: 15357163 NLM ISO Abbreviation: Mol Cancer Ther Subsets: MEDLINE

مواضيع طبية MeSH: Antineoplastic Agents, Phytogenic/*therapeutic use , Inflammation/*drug therapy , Nucleotidyltransferases/*drug effects , Paclitaxel/*therapeutic use , Taxoids/*therapeutic use , Triple Negative Breast Neoplasms/*drug therapy, Antineoplastic Agents, Phytogenic/pharmacology ; Humans ; Paclitaxel/pharmacology ; Signal Transduction ; Taxoids/pharmacology ; Triple Negative Breast Neoplasms/pathology

المؤلفون: Scribano CM; Molecular and Cellular Pharmacology Graduate Training Program, University of Wisconsin, Madison, WI 53705, USA., Wan J; Physiology Graduate Training Program, University of Wisconsin, Madison, WI 53705, USA., Esbona K; Department of Medicine, University of Wisconsin, Madison, WI 53705, USA., Tucker JB; Cancer Biology Graduate Training Program, University of Wisconsin, Madison, WI 53705, USA., Lasek A; Department of Cell and Regenerative Biology, University of Wisconsin, Madison, WI 53705, USA., Zhou AS; Molecular and Cellular Pharmacology Graduate Training Program, University of Wisconsin, Madison, WI 53705, USA., Zasadil LM; Molecular and Cellular Pharmacology Graduate Training Program, University of Wisconsin, Madison, WI 53705, USA., Molini R; Department of Cell and Regenerative Biology, University of Wisconsin, Madison, WI 53705, USA., Fitzgerald J; Molecular and Cellular Pharmacology Graduate Training Program, University of Wisconsin, Madison, WI 53705, USA., Lager AM; Wisconsin State Laboratory of Hygiene, Madison, WI 53705, USA., Laffin JJ; Wisconsin State Laboratory of Hygiene, Madison, WI 53705, USA., Correia-Staudt K; Department of Medicine, University of Wisconsin, Madison, WI 53705, USA., Wisinski KB; Department of Medicine, University of Wisconsin, Madison, WI 53705, USA., Tevaarwerk AJ; Department of Medicine, University of Wisconsin, Madison, WI 53705, USA., O'Regan R; Department of Medicine, University of Wisconsin, Madison, WI 53705, USA., McGregor SM; Department of Pathology and Laboratory Medicine, University of Wisconsin, Madison, WI 53705, USA., Fowler AM; Department of Radiology, University of Wisconsin, Madison, WI 53792, USA.; Department of Medical Physics, University of Wisconsin, Madison, WI 53705, USA.; Carbone Cancer Center, University of Wisconsin-Madison, Madison, WI 53705, USA., Chappell RJ; Department of Statistics, University of Wisconsin, Madison, WI 53705, USA., Bugni TS; School of Pharmacy, University of Wisconsin, Madison, WI 53705, USA., Burkard ME; Department of Medicine, University of Wisconsin, Madison, WI 53705, USA.; Carbone Cancer Center, University of Wisconsin-Madison, Madison, WI 53705, USA.; Department of Oncology/McArdle Laboratory for Cancer Research, University of Wisconsin, Madison, WI 53705, USA., Weaver BA; Department of Cell and Regenerative Biology, University of Wisconsin, Madison, WI 53705, USA.; Carbone Cancer Center, University of Wisconsin-Madison, Madison, WI 53705, USA.; Department of Oncology/McArdle Laboratory for Cancer Research, University of Wisconsin, Madison, WI 53705, USA.

المصدر: Science translational medicine [Sci Transl Med] 2021 Sep 08; Vol. 13 (610), pp. eabd4811. Date of Electronic Publication: 2021 Sep 08.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE

مواضيع طبية MeSH: Breast Neoplasms*/drug therapy , Breast Neoplasms*/genetics , Paclitaxel*, Chromosomal Instability ; Female ; Humans

المؤلفون: Wan J; Department of Cell and Regenerative Biology, University of Wisconsin-Madison, Madison, WI, 53705, USA., Block S; Department of Biomolecular Chemistry, University of Wisconsin-Madison, Madison, WI, 53705, USA., Scribano CM; Department of Cell and Regenerative Biology, University of Wisconsin-Madison, Madison, WI, 53705, USA., Thiry R; Department of Cell and Regenerative Biology, University of Wisconsin-Madison, Madison, WI, 53705, USA., Esbona K; Department of Pathology and Laboratory Medicine, University of Wisconsin-Madison, Madison, WI, 53705, USA., Audhya A; Department of Biomolecular Chemistry, University of Wisconsin-Madison, Madison, WI, 53705, USA.; Carbone Cancer Center, University of Wisconsin-Madison, Madison, WI, 53705, USA., Weaver BA; Department of Cell and Regenerative Biology, University of Wisconsin-Madison, Madison, WI, 53705, USA. baweaver@wisc.edu.; Carbone Cancer Center, University of Wisconsin-Madison, Madison, WI, 53705, USA. baweaver@wisc.edu.; Department of Oncology/McArdle Laboratory for Cancer Research, University of Wisconsin-Madison, Madison, WI, 53705, USA. baweaver@wisc.edu.

المصدر: Nature communications [Nat Commun] 2019 Apr 04; Vol. 10 (1), pp. 1540. Date of Electronic Publication: 2019 Apr 04.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Cell Cycle Proteins/*genetics , Nuclear Proteins/*genetics , Promyelocytic Leukemia Protein/*metabolism , Proto-Oncogene Proteins c-mdm2/*metabolism , Tumor Suppressor Protein p53/*metabolism, Animals ; Breast Neoplasms/genetics ; Cell Cycle Proteins/metabolism ; Cells, Cultured ; DNA Damage ; Escherichia coli/genetics ; Female ; HEK293 Cells ; HeLa Cells ; Humans ; M Phase Cell Cycle Checkpoints/genetics ; Mice, Nude ; Nuclear Proteins/metabolism ; Protein Domains ; Sumoylation ; Up-Regulation