نتائج البحث - "Sean Eckley"

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Figures S13-S19 from Discovery of Selective Estrogen Receptor Covalent Antagonists for the Treatment of ERαWT and ERαMUT Breast Cancer

المؤلفون: Manav Korpal, Ping Zhu, Peter G. Smith, Markus Warmuth, Lihua Yu, Shihua Yao, Michael J. Wick, Suzanne Wardell, John Wang, Frédéric H. Vaillancourt, Michael Thomas, Vanitha Subramanian, Sasirekha Sivakumar, Amy Siu, Ricardo Ribas, Nathalie Rioux, Victoria Rimkunas, Dominic J. Reynolds, Sujatha Rajagopalan, Sudeep Prajapati, Sunil Pancholi, Morgan O'Shea, John Norris, Tuong-Vi Nguyen, Alyssa Moriarty, Diana Melchers, Lesley-Ann Martin, Crystal Mackenzie, Nicholas Larsen, Weidong G. Lai, Galina Kuznetsov, Pavan Kumar, Namita Kumar, Amy Kim, Craig Karr, Jaya J. Joshi, Sean Irwin, René Houtman, Andrew Hart, Ming-Hong Hao, Peter Fekkes, Sean Eckley, Subhasree Das, Benjamin Caleb, Silvia Buonamici, David M. Bolduc, Sergei Agoulnik, Kiran Aithal, Deepti Banka, Zhenhua J. Wu, Guo Zhu Zheng, Craig Furman, Xiaoling Puyang

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d9c652f36eba7990109355ffbc45bde
https://doi.org/10.1158/2159-8290.22532926

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Supplementary Methods from Discovery of Selective Estrogen Receptor Covalent Antagonists for the Treatment of ERαWT and ERαMUT Breast Cancer

المؤلفون: Manav Korpal, Ping Zhu, Peter G. Smith, Markus Warmuth, Lihua Yu, Shihua Yao, Michael J. Wick, Suzanne Wardell, John Wang, Frédéric H. Vaillancourt, Michael Thomas, Vanitha Subramanian, Sasirekha Sivakumar, Amy Siu, Ricardo Ribas, Nathalie Rioux, Victoria Rimkunas, Dominic J. Reynolds, Sujatha Rajagopalan, Sudeep Prajapati, Sunil Pancholi, Morgan O'Shea, John Norris, Tuong-Vi Nguyen, Alyssa Moriarty, Diana Melchers, Lesley-Ann Martin, Crystal Mackenzie, Nicholas Larsen, Weidong G. Lai, Galina Kuznetsov, Pavan Kumar, Namita Kumar, Amy Kim, Craig Karr, Jaya J. Joshi, Sean Irwin, René Houtman, Andrew Hart, Ming-Hong Hao, Peter Fekkes, Sean Eckley, Subhasree Das, Benjamin Caleb, Silvia Buonamici, David M. Bolduc, Sergei Agoulnik, Kiran Aithal, Deepti Banka, Zhenhua J. Wu, Guo Zhu Zheng, Craig Furman, Xiaoling Puyang

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d273e24b0b70562bfd8ace053d7ea075
https://doi.org/10.1158/2159-8290.22532917.v1

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Tables S3-S4 from Discovery of Selective Estrogen Receptor Covalent Antagonists for the Treatment of ERαWT and ERαMUT Breast Cancer

المؤلفون: Manav Korpal, Ping Zhu, Peter G. Smith, Markus Warmuth, Lihua Yu, Shihua Yao, Michael J. Wick, Suzanne Wardell, John Wang, Frédéric H. Vaillancourt, Michael Thomas, Vanitha Subramanian, Sasirekha Sivakumar, Amy Siu, Ricardo Ribas, Nathalie Rioux, Victoria Rimkunas, Dominic J. Reynolds, Sujatha Rajagopalan, Sudeep Prajapati, Sunil Pancholi, Morgan O'Shea, John Norris, Tuong-Vi Nguyen, Alyssa Moriarty, Diana Melchers, Lesley-Ann Martin, Crystal Mackenzie, Nicholas Larsen, Weidong G. Lai, Galina Kuznetsov, Pavan Kumar, Namita Kumar, Amy Kim, Craig Karr, Jaya J. Joshi, Sean Irwin, René Houtman, Andrew Hart, Ming-Hong Hao, Peter Fekkes, Sean Eckley, Subhasree Das, Benjamin Caleb, Silvia Buonamici, David M. Bolduc, Sergei Agoulnik, Kiran Aithal, Deepti Banka, Zhenhua J. Wu, Guo Zhu Zheng, Craig Furman, Xiaoling Puyang

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::448ee55b6f74e7115d7952f4c0f92306
https://doi.org/10.1158/2159-8290.22532911.v1

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Supplementary File from Peripheral Neuropathy Induced by Microtubule-Targeted Chemotherapies: Insights into Acute Injury and Long-term Recovery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41c8fe14a2eaf120d0d4176f58a513a6
https://doi.org/10.1158/0008-5472.22417085

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Data from Peripheral Neuropathy Induced by Microtubule-Targeted Chemotherapies: Insights into Acute Injury and Long-term Recovery

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18ede1532c2b073e39e9d7c1ef288c76
https://doi.org/10.1158/0008-5472.c.6509738

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Discovery of Selective Estrogen Receptor Covalent Antagonists for the Treatment of ERαWT and ERαMUT Breast Cancer

المؤلفون: Sean Eckley, Markus Warmuth, Ping Zhu, Deepti Banka, Zhenhua J. Wu, Nicholas A. Larsen, Sudeep Prajapati, Ricardo Ribas, Ming-Hong Hao, Pavan Kumar, Pete Smith, Michael J. Wick, Kiran Aithal, Crystal Mackenzie, John D. Norris, Sasirekha Sivakumar, V. Subramanian, Tuong-Vi Nguyen, Lihua Yu, Sean Irwin, Andrew Hart, Craig Furman, Alyssa Moriarty, Amy Kim, Benjamin Caleb, O'shea Morgan Welzel, Craig Karr, Sunil Pancholi, Frédéric H. Vaillancourt, Silvia Buonamici, Manav Korpal, Namita Kumar, Weidong G. Lai, Diana Melchers, Peter Fekkes, René Houtman, Lesley-Ann Martin, Xiaoling Puyang, Victoria Rimkunas, Michael Thomas, Amy Siu, Reynolds Dominic, Sujatha Rajagopalan, Suzanne E. Wardell, John Wang, Jaya Julie Joshi, Zheng Guo Zhu, David M. Bolduc, Nathalie Rioux, Subhasree Das, Sergei Agoulnik, Shihua Yao, Galina Kuznetsov

المصدر: Cancer Discovery. 8:1176-1193

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::0120259fcf7ad9215e86543a6ac089d0
https://doi.org/10.1158/2159-8290.cd-17-1229

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Bicyclic azetidines kill the diarrheal pathogen Cryptosporidium in mice by inhibiting parasite phenylalanyl-tRNA synthetase

المصدر: Science Translational Medicine. 12

مصطلحات موضوعية: 0301 basic medicine, biology, Bicyclic molecule, 030106 microbiology, Cryptosporidium, General Medicine, biology.organism_classification, In vitro, Microbiology, 03 medical and health sciences, Drug repositioning, 030104 developmental biology, Cryptosporidium parvum, parasitic diseases, Parasite hosting, Pathogen, EC50

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::d13029b67e787a6f32622aa1a3983584
https://doi.org/10.1126/scitranslmed.aba8412

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Abstract P1-10-08: Development of a first-in-class oral selective ERα covalent antagonist (SERCA) for the treatment of ERαWT and ERαMUT breast cancer

المؤلفون: Sean Irwin, Guo-Zhu Zheng, Sherri Smith, Craig Furman, Deepti Banka, Nathalie Rioux, Victoria Rimkunas, J Norris, Prashant Kumar, Nicholas A. Larsen, Y Yu, Anand Selvaraj, Sergei Agoulnik, Craig Karr, Andrew Hart, T Bowser, Lorna Helen Mitchell, Crystal MacKenzie, Huilan Yao, Pete Smith, Tarek Sahmoud, Peter Fekkes, Jiayi Wu, T-V Nguyen, Zhaojie Zhang, Frédéric H. Vaillancourt, Betty Chan, Mike Thomas, Benjamin Caleb, O'shea Morgan Welzel, Manav Korpal, Markus Warmuth, Ping Zhu, S Wardell, Amy K. Kim, Galina Kuznetsov, Sean Eckley, Allison Davis, Sudeep Prajapati, Jun Wang, Ming-Hong Hao, V. Subramanian, Naresh Kumar, Xiaoling Puyang, Lihua Yu, Jaya Julie Joshi, Reynolds Dominic, G W Lai

المصدر: Cancer Research. 78:P1-10

مصطلحات موضوعية: Cancer Research, Fulvestrant, Chemistry, Antagonist, Estrogen receptor, medicine.disease, Breast cancer, Oncology, Mechanism of action, Cancer research, medicine, medicine.symptom, Receptor, Estrogen receptor alpha, Tamoxifen, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::07d855e8c12d90a391ebb18e38827bdf
https://doi.org/10.1158/1538-7445.sabcs17-p1-10-08

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Abstract DDT01-04: Discovery and development of H3B-6545: A novel, oral, selective estrogen receptor covalent antagonist (SERCA) for the treatment of breast cancer

المصدر: Cancer Research. 77:DDT01-04

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::71b5b0fa7e9d8e6795b2dcf66171548d
https://doi.org/10.1158/1538-7445.am2017-ddt01-04

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Diversity-oriented synthesis yields novel multistage antimalarial inhibitors

المؤلفون: Daniel E. Neafsey, Dyann F. Wirth, Jon Clardy, Arvind Sharma, Ping S. Lui, Anne-Marie Zeeman, Sean Eckley, Yvonne Van Gessel, Mathias Wawer, Matthias Marti, Elizabeth A. Winzeler, Elamaran Meibalan, Nobutaka Kato, Benito Munoz, Emily R. Derbyshire, Stuart L. Schreiber, Marshall L. Morningstar, Jeremy R. Duvall, Clemens H. M. Kocken, Eli L. Moss, Bennett C. Meier, Joshua A. Bittker, Vicky M. Avery, Manmohan Sharma, John E. Burke, Eamon Comer, Jacob A. McPhail, Maurice A. Itoe, Jessica Bastien, Nicolas M. B. Brancucci, Branko Mitasev, David Clarke, Timothy A. Lewis, Victoria C. Corey, Sandra Duffy, Tomoyo Sakata-Kato, Fabian Gusovsky, Sandra March, Takashi Yoshinaga, Gillian L. Dornan, Flaminia Catteruccia, Morgane Sayes, Emily Lund, Christina Scherer, Sangeeta N. Bhatia, Michael Foley, Amit Sharma, Amanda K. Lukens, Paul A. Clemons, Koen J. Dechering, Karin M. J. Koolen, Micah Maetani

المصدر: Nature

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7124959dd9190076f4edcf04f4cc1a3b

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