المؤلفون: Nicole K Polinski, Terina N Martinez, Alexander Gorodinsky, Ralph Gareus, Michael Sasner, Mark Herberth, Robert Switzer, Syed O Ahmad, Mali Cosden, Monika Kandebo, Robert E Drolet, Peter D Buckett, Weisong Shan, Yi Chen, Lee J Pellegrino, Gregory D Ellsworth, Leo B Dungan, Warren D Hirst, Sean W Clark, Kuldip D Dave

المصدر: PLoS ONE, Vol 16, Iss 6, p e0252325 (2021)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/294b88f9cc54498d84ccf437a6bd2775

المؤلفون: Nicole K. Polinski, Terina N. Martinez, Sylvie Ramboz, Michael Sasner, Mark Herberth, Robert Switzer, Syed O. Ahmad, Lee J. Pelligrino, Sean W. Clark, Jacob N. Marcus, Sean M. Smith, Kuldip D. Dave, Mark A. Frasier

المصدر: Disease Models & Mechanisms, Vol 15, Iss 6 (2022)

مصطلحات موضوعية: gcase, alpha-synuclein, parkinson's disease, Medicine, Pathology, RB1-214

وصف الملف: electronic resource

Relation: http://dmm.biologists.org/content/15/6/dmm049192; https://doaj.org/toc/1754-8403; https://doaj.org/toc/1754-8411

URL الوصول: https://doaj.org/article/2ff4a4f7438a460f8a91ec3fc7c58bc4

المؤلفون: Lee Pellegrino, Monika Kandebo, Nicole K. Polinski, Mark Herberth, Leo B. Dungan, Robert Switzer, Gregory D. Ellsworth, Sean W. Clark, Alexander Gorodinsky, Robert E. Drolet, Peter D. Buckett, Mali Cosden, Michael Sasner, Ralph Gareus, Syed Omar Ahmad, Weisong Shan, Terina N. Martinez, Kuldip D. Dave, Warren D. Hirst, Yi Chen

المصدر: PLoS ONE
PLoS ONE, Vol 16, Iss 6, p e0252325 (2021)

مصطلحات موضوعية: Male, Heredity, medicine.disease_cause, Hippocampus, Homozygosity, chemistry.chemical_compound, Mice, Medical Conditions, Medicine and Health Sciences, Gene Knock-In Techniques, Mutation, Multidisciplinary, Movement Disorders, Heterozygosity, Brain, Neurodegenerative Diseases, Parkinson Disease, Glycosphingolipid, Animal Models, Phenotype, Cell biology, Experimental Organism Systems, Neurology, Liver, Medicine, Glucosylceramidase, Female, medicine.symptom, Cellular Structures and Organelles, Anatomy, medicine.drug, Research Article, Science, Immunoblotting, Inflammation, Substantia nigra, Mouse Models, Mice, Transgenic, Biology, Research and Analysis Methods, Glycosphingolipids, Model Organisms, Parkinsonian Disorders, Dopamine, medicine, Genetics, Point Mutation, Animals, Gene, Point mutation, Biology and Life Sciences, Cell Biology, Mice, Inbred C57BL, chemistry, Animal Studies, Lysosomes

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5768efebed44f52b94d2247e7ec2bf9
http://europepmc.org/articles/PMC8189458

المؤلفون: Leo B. Dungan, Hui H. Chang, Sean W. Clark, Nastry Brignol, Michelle Frascella, Kenneth J. Valenzano, Richie Khanna, Elfrida R. Benjamin, Robert Boyd, Rick Hamler, Sean Morrison

المصدر: Analytical Chemistry. 89:8288-8295

مصطلحات موضوعية: 0301 basic medicine, Brain tissue, Neuronopathic Gaucher Disease, Glucosylceramides, Tandem mass spectrometry, Significant elevation, Analytical Chemistry, 03 medical and health sciences, Tandem Mass Spectrometry, In vivo, Liquid chromatography–mass spectrometry, Animals, chemistry.chemical_classification, Gaucher Disease, Chemistry, beta-Glucosidase, Psychosine, Brain, Mice, Inbred C57BL, Chromatographic separation, 030104 developmental biology, Enzyme, Biochemistry, Glucosylceramidase, Biomarkers, Chromatography, Liquid

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e69e1fa18dc483218406547e0df9d4e
https://doi.org/10.1021/acs.analchem.7b01442

المؤلفون: David J. Lockhart, Sindalana Hean, Lee Pellegrino, Sheila M. Fleming, Melanie B. Watson, Farzad Mortazavi, Franziska Richter, Caitlin K. Mulligan, Brian Ranes, Chunni Zhu, Richie Khanna, John J. Flanagan, Sean W. Clark, Pedrom C. Sioshansi, Krystal De La Rosa, Vincent Lemesre, Brandon Wustman, Marie-Françoise Chesselet

المصدر: Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, vol 11, iss 4

مصطلحات موضوعية: Male, Parkinson's disease, Chaperone, Neurodegenerative, Pharmacology, Mice, chemistry.chemical_compound, Motor behavior, 2.1 Biological and endogenous factors, Pharmacology (medical), Aetiology, Tartrates, Acid-beta-glucosidase, biology, beta-Glucosidase, Dopaminergic, Brain, Parkinson Disease, Pharmacology and Pharmaceutical Sciences, Substantia Nigra, Pharmacological chaperone, Protein Transport, 5.1 Pharmaceuticals, Neurological, alpha-Synuclein, Public Health and Health Services, Original Article, Development of treatments and therapeutic interventions, Imino Pyranoses, medicine.drug, Substantia nigra, Motor Activity, Mouse model, Alpha-synuclein, Protein Aggregates, medicine, Animals, Humans, Synucleinopathies, Neurology & Neurosurgery, Animal, Dopaminergic Neurons, Prevention, Neurosciences, medicine.disease, Brain Disorders, Disease Models, Animal, nervous system, chemistry, Chaperone (protein), Disease Models, biology.protein, Acid-β-glucosidase, Neurology (clinical), Glucocerebrosidase, Neuroscience

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9efd5833a91243954673e6041ea0a90d
https://doi.org/10.1007/s13311-014-0294-x

المؤلفون: Peggy P. Li, Akira Nakanishi, Harumi Kasamatsu, Sean W. Clark

المصدر: Proceedings of the National Academy of Sciences. 99:1353-1358

مصطلحات موضوعية: Models, Molecular, Cytoplasm, Protein Folding, Macromolecular Substances, Protein Conformation, Pentamer, Stereochemistry, viruses, Succinimides, Simian virus 40, Sulfur Radioisotopes, Oligomer, Cell Line, chemistry.chemical_compound, Capsid, Methionine, Protein structure, Chlorocebus aethiops, Animals, Disulfides, Protein disulfide-isomerase, Multidisciplinary, Chemistry, Biological Sciences, Crystallography, Cross-Linking Reagents, Monomer, Covalent bond, Capsid Proteins, Protein folding, Oxidation-Reduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb171d83d11358615440fbffd09982d5
https://doi.org/10.1073/pnas.032668699

المؤلفون: Sean W. Clark, Erika L. F. Holzbaur, Bryce Mark Paschal, Olivier Staub, Richard B. Vallee, David I. Meyer, Imran B. Clark

المصدر: Molecular Biology of the Cell. 5:1301-1310

مصطلحات موضوعية: Gene isoform, DNA, Complementary, Molecular Sequence Data, Biology, Cytosol, Dogs, Complementary DNA, Animals, Humans, Electrophoresis, Gel, Two-Dimensional, Tissue Distribution, Amino Acid Sequence, RNA, Messenger, Molecular Biology, Peptide sequence, Actin, chemistry.chemical_classification, Messenger RNA, Expressed sequence tag, Nucleic acid sequence, Dynactin Complex, Cell Biology, Molecular biology, Actins, Amino acid, chemistry, Microtubule Proteins, Microtubule-Associated Proteins, HeLa Cells, Research Article

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::697558adaefa2303072e95dc1fba9dca
https://doi.org/10.1091/mbc.5.12.1301

المؤلفون: David I. Meyer, Sean W. Clark

المصدر: The Journal of Cell Biology
The Journal of cell biology, vol 127, iss 1

مصطلحات موضوعية: Spores, Saccharomyces cerevisiae Proteins, Messenger, Saccharomyces cerevisiae, Genes, Fungal, Molecular Sequence Data, Sequence Homology, Locus (genetics), Sequence alignment, Spindle Apparatus, Medical and Health Sciences, Fungal Proteins, Amino Acid Sequence, RNA, Messenger, Cloning, Molecular, DNA, Fungal, Peptide sequence, Actin, Phylogeny, Sequence Deletion, Genetics, Fungal protein, biology, Base Sequence, Sequence Homology, Amino Acid, Molecular, Nuclear Proteins, RNA, Fungal, DNA, Cell Biology, Articles, Sequence Analysis, DNA, Biological Sciences, Spores, Fungal, biology.organism_classification, Yeast, Actins, Spindle apparatus, Amino Acid, Fungal, Genes, RNA, Sequence Analysis, Sequence Alignment, Cell Division, Cloning, Developmental Biology

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e722eb1372499af0cd4f903d145390aa
http://europepmc.org/articles/PMC2120173

المؤلفون: Sean W. Clark, Erika L. F. Holzbaur, David I. Meyer, K. Kevin Pfister, Richard B. Vallee, Bryce M. Paschal

المصدر: Journal of Biological Chemistry. 268:15318-15323

مصطلحات موضوعية: Cytosol, Biochemistry, Microtubule, Immunoprecipitation, Protein subunit, Dynein, Dynactin, Cell Biology, Biology, Molecular Biology, ACTR1A, Actin

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::eaa85172bfa1468362c7c87d81c7a0c9
https://doi.org/10.1016/s0021-9258(18)82472-3

المؤلفون: Sean W. Clark, David I. Meyer

المصدر: Nature. 359:246-250

مصطلحات موضوعية: Blotting, Western, Molecular Sequence Data, Clone (cell biology), Sequence alignment, Cross Reactions, Biology, Cell Fractionation, Polymerase Chain Reaction, Homology (biology), Dogs, Sequence Homology, Nucleic Acid, Complementary DNA, Animals, Electrophoresis, Gel, Two-Dimensional, Tissue Distribution, Amino Acid Sequence, RNA, Messenger, Gene, ACTR1A, Actin, Gene Library, Organelles, Genetics, Multidisciplinary, Base Sequence, Blotting, Northern, Actins, Microscopy, Fluorescence, Centrosome, Poly A

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::203e57dcfd90f9f7f106eedad2ad3344
https://doi.org/10.1038/359246a0