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المؤلفون: Shingo Kajimura, Lawrence Kazak, Dina Laznik-Bogoslavski, Bruce M. Spiegelman, Paul Cohen, Mark P. Jedrychowski, Sebastian C. Hasenfuss, Ramalingam Vetrivelan, Kosaku Shinoda, Edward T. Chouchani, Steve P. Gygi, Brian K. Erickson, Gina Z. Lu
المصدر: Cell. 163:643-655
مصطلحات موضوعية: medicine.medical_specialty, Adipose tissue, Mitochondrion, Creatine, Ion Channels, General Biochemistry, Genetics and Molecular Biology, Mitochondrial Proteins, Mice, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Adipose Tissue, Brown, Internal medicine, medicine, Animals, Homeostasis, Humans, Obesity, Uncoupling Protein 1, 030304 developmental biology, 0303 health sciences, biology, Biochemistry, Genetics and Molecular Biology(all), Futile cycle, Thermogenesis, Thermogenin, Mitochondria, Adenosine Diphosphate, Endocrinology, Adipose Tissue, chemistry, biology.protein, Creatine kinase, Energy Metabolism, 030217 neurology & neurosurgery
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المؤلفون: Latifa Bakiri, Erwin F. Wagner, Mathias Müller, I Custic, Andreas Eger, Sabine Macho-Maschler, Ana Guío-Carrión, J Niemiec, Sebastian C. Hasenfuss, Hartmut Beug
المصدر: Cell Death & Differentiation. 22:336-350
مصطلحات موضوعية: Epithelial-Mesenchymal Transition, Breast Neoplasms, Biology, medicine.disease_cause, Mice, Transforming Growth Factor beta, Cell Line, Tumor, Embryonic morphogenesis, medicine, Animals, Humans, Gene silencing, Epithelial–mesenchymal transition, Mammary Glands, Human, Promoter Regions, Genetic, Molecular Biology, Transcription factor, Zinc Finger E-box Binding Homeobox 2, Homeodomain Proteins, Original Paper, Zinc Finger E-box-Binding Homeobox 1, Epithelial Cells, Promoter, Cell Biology, Transforming growth factor beta, Cadherins, Molecular biology, Cell biology, Repressor Proteins, Transcription Factor AP-1, Disease Models, Animal, biology.protein, Female, Ectopic expression, Carcinogenesis, Proto-Oncogene Proteins c-fos, Transcription Factors
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المؤلفون: Martin K. Thomsen, Osvaldo Graña, Ana Guío-Carrión, Lola Martinez, Erwin F. Wagner, Ramon Campos-Olivas, Hans Peter Dienes, Sebastian C. Hasenfuss, Rainer Hamacher, Latifa Bakiri
المساهمون: European Research Council, Worldwide Cancer Research, Ministerio de Economía y Competitividad (España), Deutsche Forschungsgemeinschaft (Alemania), AUFF Nova, Boehringer Ingelheim Fonds
المصدر: Repisalud
Instituto de Salud Carlos III (ISCIII)
The Journal of Experimental Medicine
Bakiri, L, Hamacher, R, Graña, O, Guío-Carrión, A, Campos-Olivas, R, Martinez, L, Dienes, H P, Thomsen, M K, Hasenfuss, S C & Wagner, E F 2017, ' Liver carcinogenesis by FOS-dependent inflammation and cholesterol dysregulation ', Journal of Experimental Medicine, vol. 214, no. 5 . https://doi.org/10.1084/jem.20160935مصطلحات موضوعية: 0301 basic medicine, Carcinoma, Hepatocellular, DNA damage, Immunology, Inflammation, Biology, Article, 03 medical and health sciences, Mice, Journal Article, medicine, Immunology and Allergy, Animals, Drosophila Proteins, Diethylnitrosamine, Transcription factor, Research Articles, Sulindac, Liver Neoplasms, HCCS, medicine.disease, digestive system diseases, Repressor Proteins, Disease Models, Animal, 030104 developmental biology, medicine.anatomical_structure, Cell Transformation, Neoplastic, Cholesterol, Nuclear receptor, Liver, Hepatocyte, Cancer research, medicine.symptom, Liver cancer, Proto-Oncogene Proteins c-fos, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f2fda0f710fb2fe5c999a07eb601bfe
http://hdl.handle.net/20.500.12105/8391 -
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المؤلفون: N J F van den Broek, Judith Campisi, D Putavet, D C van Gent, Boudewijn M.T. Burgering, P L J de Keizer, J.H.J. Hoeijmakers, M P Baar, Arjan B. Brenkman, K.A.T. Naipal, Flore Kruiswijk, Renuka Sivapatham, P.J. van der Spek, Wim H. J. Kruit, Sebastian C. Hasenfuss
المساهمون: Molecular Genetics, Medical Oncology, Pathology
المصدر: Oncogene, 35(17), 2166-2177. Nature Publishing Group
Oncogene
Oncogene, 35(17), 2166. Nature Publishing Groupمصطلحات موضوعية: 0301 basic medicine, Cancer Research, Indoles, medicine.medical_treatment, Molecular Targeted Therapy, Neoplasm Metastasis, Vemurafenib, Non-U.S. Gov't, Melanoma, Sulfonamides, Tumor, Research Support, Non-U.S. Gov't, Cell cycle, 3. Good health, Gene Expression Regulation, Neoplastic, Original Article, medicine.drug, Signal Transduction, Proto-Oncogene Proteins B-raf, Biology, Research Support, Cell Line, N.I.H, 03 medical and health sciences, Research Support, N.I.H., Extramural, SDG 3 - Good Health and Well-being, Cell Line, Tumor, medicine, Journal Article, Genetics, Humans, Protein Kinase Inhibitors, Molecular Biology, neoplasms, Neoplastic, Oncogene, Forkhead Box Protein M1, Extramural, Immunotherapy, medicine.disease, NIMA-Interacting Peptidylprolyl Isomerase, 030104 developmental biology, Gene Expression Regulation, Immunology, Mutation, FOXM1, Cancer research, Skin cancer, V600E
وصف الملف: application/pdf; image/pdf
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المؤلفون: Sebastian C. Hasenfuss, Martin K. Thomsen, H Wu, M Morente, Erwin F. Wagner, Latifa Bakiri
المصدر: Europe PubMed Central
مصطلحات موضوعية: Cyclin-Dependent Kinase Inhibitor p21, Male, Aging, JUNB, Population, Down-Regulation, Prostate cancer, Mice, Prostate, hemic and lymphatic diseases, medicine, Tensin, PTEN, Animals, Calgranulin B, Humans, Calgranulin A, Neoplasm Invasiveness, Osteopontin, RNA, Messenger, education, Molecular Biology, Cyclin-Dependent Kinase Inhibitor p16, Mice, Knockout, Original Paper, education.field_of_study, biology, PTEN Phosphohydrolase, Cancer, Prostatic Neoplasms, Cell Biology, medicine.disease, Mice, Inbred C57BL, medicine.anatomical_structure, Editorial, Cancer research, biology.protein, Disease Progression, Signal Transduction, Transcription Factors
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المؤلفون: P. Hasselblatt, Erwin F. Wagner, Latifa Bakiri, Sebastian C. Hasenfuss, Martin K. Thomsen, Ana Guío-Carrión
المصدر: Journal of Hepatology. 64:S156-S157
مصطلحات موضوعية: Hepatology, Chemistry, medicine, Cancer research, Liver cancer, medicine.disease
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المؤلفون: Martin K. Thomsen, Erwin F. Wagner, Latifa Bakiri, Evan G. Williams, Sebastian C. Hasenfuss, Johan Auwerx
المصدر: Cell metabolism
مصطلحات موضوعية: medicine.medical_specialty, Physiology, Regulator, Peroxisome proliferator-activated receptor, Biology, digestive system, Article, Antigen, Internal medicine, Nonalcoholic fatty liver disease, medicine, Animals, Humans, Molecular Biology, Steatohepatitis, Regulation of gene expression, chemistry.chemical_classification, NASH, nutritional and metabolic diseases, Cell Biology, medicine.disease, digestive system diseases, Fatty Liver, PPAR gamma, Transcription Factor AP-1, Endocrinology, chemistry, Cell culture, Cancer research, Signal transduction, Protein Multimerization, Signal Transduction
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3444c31590a1a94a9ed86f89933a7a4
https://europepmc.org/articles/PMC4023468/ -
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المؤلفون: Erwin F. Wagner, Sebastian C. Hasenfuss, Martin K. Thomsen, Rainer Hamacher, Latifa Bakiri
المصدر: Hasenfuss, S C, Bakiri, L, Thomsen, M K, Hamacher, R & Wagner, E F 2014, ' Activator Protein 1 transcription factor Fos-related antigen 1 (Fra-1) is dispensable for murine liver fibrosis, but modulates xenobiotic metabolism ' Hepatology, vol. 59, no. 1, pp. 261-73 . https://doi.org/10.1002/hep.26518
Hepatologyمصطلحات موضوعية: Liver Cirrhosis, medicine.medical_specialty, Cell, Biology, Chemokine CXCL9, Xenobiotics, Bile Acids and Salts, 03 medical and health sciences, GSTP1, Mice, 0302 clinical medicine, Fibrosis, Internal medicine, medicine, Journal Article, Animals, Homeostasis, Transcription factor, 030304 developmental biology, Acetaminophen, Glutathione Transferase, Regulation of gene expression, Liver injury, 0303 health sciences, Hepatology, Research Support, Non-U.S. Gov't, Promoter, medicine.disease, Adaptation, Physiological, Cell biology, Isoenzymes, Disease Models, Animal, medicine.anatomical_structure, Gene Expression Regulation, Glutathione S-Transferase pi, 030220 oncology & carcinogenesis, Immunology, Inactivation, Metabolic, Hepatocytes, Chemical and Drug Induced Liver Injury, Proto-Oncogene Proteins c-fos
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::218d3fa6c481de0534a926642b21890a
https://pure.au.dk/portal/da/publications/activator-protein-1-transcription-factor-fosrelated-antigen-1-fra1-is-dispensable-for-murine-liver-fibrosis-but-modulates-xenobiotic-metabolism(c905159c-544d-4ce0-9df2-5eccb67f9c09).html -
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المؤلفون: Sebastian C. Hasenfuss, Lola Martinez, Erwin F. Wagner, Latifa Bakiri, Rainer Hamacher, Martin K. Thomsen
المصدر: Thomsen, M K, Bakiri, L, Hasenfuss, S C, Hamacher, R, Martinez, L & Wagner, E F 2013, ' JUNB/AP-1 controls IFN-γ during inflammatory liver disease ' Journal of Clinical Investigation, vol. 123, no. 12, pp. 5258-68 . https://doi.org/10.1172/JCI70405
مصطلحات موضوعية: Transcription, Genetic, JUNB, Recombinant Fusion Proteins, chemical and pharmacologic phenomena, Inflammation, Galactosylceramides, Biology, Hepatitis, 03 medical and health sciences, Liver disease, Interferon-gamma, Mice, 0302 clinical medicine, Immune system, Transduction, Genetic, hemic and lymphatic diseases, medicine, Concanavalin A, Journal Article, Animals, Humans, STAT1, 030304 developmental biology, 0303 health sciences, Cell Death, Research Support, Non-U.S. Gov't, General Medicine, medicine.disease, Natural killer T cell, 3. Good health, Killer Cells, Natural, Mice, Inbred C57BL, IRF1, Poly I-C, STAT1 Transcription Factor, Immunology, biology.protein, Cancer research, Hepatocytes, Natural Killer T-Cells, medicine.symptom, Chemical and Drug Induced Liver Injury, Research Article, 030215 immunology, Interferon Regulatory Factor-1, Transcription Factors
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31b6f2f272ba495152ebce69167fc700
https://pure.au.dk/portal/da/publications/junbap1-controls-ifn-during-inflammatory-liver-disease(e16817e6-456c-4098-bcf1-6c69d97c8e87).html -
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المؤلفون: Latifa Bakiri, Erwin F. Wagner, Sebastian C. Hasenfuss
المصدر: Cell Cycle
مصطلحات موضوعية: Pparg, Proto-Oncogene Proteins c-jun, Peroxisome proliferator-activated receptor, Biology, Editorials: Cell Cycle Features, Fra-2, Fra-1, Liver disorder, Adenoviridae, Mice, Non-alcoholic Fatty Liver Disease, Lipid droplet, Cell Line, Tumor, medicine, hepatocyte, Animals, Humans, Enhancer, Molecular Biology, Transcription factor, mouse, Jun, chemistry.chemical_classification, Fos, Fatty liver, Cell Biology, medicine.disease, Lipid Metabolism, 3. Good health, Fatty Liver, PPAR gamma, Transcription Factor AP-1, FLD, chemistry, Biochemistry, Gene Expression Regulation, Liver, Hepatocytes, Signal transduction, Steatohepatitis, Protein Multimerization, transcription, Proto-Oncogene Proteins c-fos, Developmental Biology, Signal Transduction