المؤلفون: Alves, Suélen Santos, da Silva Junior, Rui Milton Patrício, Delfino-Pereira, Polianna, Pereira, Marilia Gabriella Alves Goulart, Vasconcelos, Israel, Schwaemmle, Hanna, Mazzei, Rodrigo Focosi, Carlos, Maiko Luiz, Espreafico, Enilza Maria, Tedesco, Antônio Claudio, Sebollela, Adriano, Almeida, Sebastião Sousa, de Oliveira, José Antônio Cortes, Garcia-Cairasco, Norberto^{Aff1, Aff8, IDs1203502202810w_cor14}

المصدر: Molecular Neurobiology. 59(6):3721-3737

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المؤلفون: Selles, Maria Clara, Fortuna, Juliana T.S., Cercato, Magali C., Santos, Luis Eduardo, Domett, Luciana, Bitencourt, Andre L.B., Carraro, Mariane Favero, Souza, Amanda S., Janickova, Helena, Azevedo, Caroline Vieira, Campos, Henrique Correia, de Souza, Jorge M., Alves-Leon, Soniza, Prado, Vania F., Prado, Marco A.M., Epstein, Alberto L., Salvetti, Anna, Longo, Beatriz Monteiro, Arancio, Ottavio, Klein, William L., Sebollela, Adriano, De Felice, Fernanda G., Jerusalinsky, Diana A., Ferreira, Sergio T.

المصدر: In Molecular Therapy November 2022

المؤلفون: Giovanna O. Nogueira, Patricia P. Garcez, Cedric Bardy, Mark O. Cunningham, Adriano Sebollela

المصدر: Frontiers in Neuroscience, Vol 16 (2022)

مصطلحات موضوعية: human, tissue, CNS, cell reprogramming, slices, disease models, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fnins.2022.838594/full; https://doaj.org/toc/1662-453X

URL الوصول: https://doaj.org/article/fa05b6bffe7f4ce086333a62b5c8f484

المؤلفون: Catalão, Carlos Henrique Rocha, Santos-Junior, Nilton Nascimento, da Costa, Luís Henrique Angenendt, Souza, Anderson Oliveira, Cárnio, Evelin Capellari, Sebollela, Adriano, Alberici, Luciane Carla, Rocha, Maria José Alves^Aff5

المصدر: Neurotoxicity Research: Neurodegeneration, Neuroregeneration, Neurotrophic Action, and Neuroprotection. 38(4):871-886

المؤلفون: Glaucia M. Almeida, Juliano P. Souza, Niele D. Mendes, Marjorie C. Pontelli, Nathalia R. Pinheiro, Giovanna O. Nogueira, Ricardo S. Cardoso, Isadora M. Paiva, Gustavo D. Ferrari, Flávio P. Veras, Fernando Q. Cunha, Jose A. C. Horta-Junior, Luciane C. Alberici, Thiago M. Cunha, Guilherme G. Podolsky-Gondim, Luciano Neder, Eurico Arruda, Adriano Sebollela

المصدر: Frontiers in Neuroscience, Vol 15 (2021)

مصطلحات موضوعية: arboviruses, viral encephalitis, histocultures, neuroinflammation, neuroinfection, neurotropic virus, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571

وصف الملف: electronic resource

Relation: https://www.frontiersin.org/articles/10.3389/fnins.2021.674576/full; https://doaj.org/toc/1662-453X

URL الوصول: https://doaj.org/article/9906ed265b86407d84abf4ac068b9fc7

المؤلفون: Artur Fernandes, author^{1, 2}, Niele Dias Mendes, author^{1, 3}, Glaucia Maria Almeida, author¹, Giovanna Orlovski Nogueira, author¹, Carla de Moraes Machado, author⁴, Jose de Anchieta de Castro Horta-Junior, author⁴, João Alberto Assirati Junior, author⁵, Norberto Garcia-Cairasco, author², Luciano Neder, author³, Adriano Sebollela, author¹

المصدر: Journal of Visualized Experiments. (153)

الإتاحة: http://www.jove.com/video/59845

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المؤلفون: Maria Clara Selles, Juliana T.S. Fortuna, Magali C. Cercato, Luis Eduardo Santos, Luciana Domett, Andre L.B. Bitencourt, Mariane Favero Carraro, Amanda S. Souza, Helena Janickova, Caroline Vieira Azevedo, Henrique Correia Campos, Jorge M. de Souza, Soniza Alves-Leon, Vania F. Prado, Marco A.M. Prado, Alberto L. Epstein, Anna Salvetti, Beatriz Monteiro Longo, Ottavio Arancio, William L. Klein, Adriano Sebollela, Fernanda G. De Felice, Diana A. Jerusalinsky, Sergio T. Ferreira

المساهمون: New York University School of Medicine (NYU Grossman School of Medicine), Universidade Federal do Rio de Janeiro (UFRJ), Universidad de Buenos Aires [Buenos Aires] (UBA), Universidade de São Paulo = University of São Paulo (USP), University of Western Ontario (UWO), Universidade Federal de São Paulo, Hospital Universitário Clementino Fraga Filho [Rio de Janeiro] (HUCFF / UFRJ), Handicap neuromusculaire : Physiopathologie, Biothérapie et Pharmacologies appliquées (END-ICAP), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Institut National de la Santé et de la Recherche Médicale (INSERM), Centre International de Recherche en Infectiologie (CIRI), École normale supérieure de Lyon (ENS de Lyon)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Université Jean Monnet - Saint-Étienne (UJM)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Columbia University [New York], Northwestern University [Evanston], Queen's University [Kingston, Canada], 16/820,269, Northwestern University, NU, Canadian Institutes of Health Research, IRSC: PJT 159781, PJT 162431, Alzheimer Society, Fundação de Amparo à Pesquisa do Estado de São Paulo, FAPESP: 2014/25681-3, Coordenação de Aperfeiçoamento de Pessoal de Nível Superior, CAPES, Consejo Nacional de Investigaciones Científicas y Técnicas, CONICET, Conselho Nacional de Desenvolvimento Científico e Tecnológico, CNPq, Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro, FAPERJ, Instituto Nacional de Ciência e Tecnologia de Neurociência Translacional, INCT-INNT, International Society for Neurochemistry, ISN, S.T.F. and F.G.D.F. were supported by grants from the National Council for Scientific and Technological Development (CNPq/Brazil), Fundação de Amparo à Pesquisa do Estado do Rio de Janeiro (FAPERJ/Brazil), and National Institute of Translational Neuroscience (Brazil). S.T.F. and D.A.J. were jointly supported by a binational research grant from CNPq/CONICET. A. Sebollela was supported by the São Paulo Research Foundation (FAPESP) grant 2014/25681-3 . M.A.M.P. and V.F.P. received support from the Alzheimer’s Society of Canada and the Canadian Institutes of Health Research (CIHR, PJT 162431 and PJT 159781 ). A.L.B.B. received a predoctoral fellowship from CNPq. M.C.S. received predoctoral fellowships from CNPq and FAPERJ and travel grants from the International Society for Neurochemistry , Company of Biologists , and Coordenação de Aperfeiçoamento de Pessoal de Nível Superior . We thank Drs. Moses Chao and Mauricio M. Oliveira for critical reading of the manuscript and discussions., S.T.F. and F.G.D.F. were supported by grants from the National Council for Scientific and Technological Development (CNPq/Brazil), Fundação de Amparo à Pesquisa do Estado do Rio de Janeiro (FAPERJ/Brazil), and National Institute of Translational Neuroscience (Brazil). S.T.F. and D.A.J. were jointly supported by a binational research grant from CNPq/CONICET. A. Sebollela was supported by the São Paulo Research Foundation (FAPESP) grant 2014/25681-3. M.A.M.P. and V.F.P. received support from the Alzheimer's Society of Canada and the Canadian Institutes of Health Research (CIHR, PJT 162431 and PJT 159781). A.L.B.B. received a predoctoral fellowship from CNPq. M.C.S. received predoctoral fellowships from CNPq and FAPERJ and travel grants from the International Society for Neurochemistry, Company of Biologists, and Coordenação de Aperfeiçoamento de Pessoal de Nível Superior. We thank Drs. Moses Chao and Mauricio M. Oliveira for critical reading of the manuscript and discussions. M.C.S. D.A.J. and S.T.F. designed the study. A. Sebollela, W.L.K. and S.T.F. developed the recombinant NUsc1 scFv. D.A.J. A.L.E. A. Salvetti, and S.T.F. conceived constructs and vector development. M.C.S. J.T.S.F. M.C.C. L.E.S. L.D. A.L.B.B. M.F.C. A.S.S. H.J. C.V.A. and H.C.C. performed research. M.C.S. J.T.S.F. M.C.C. L.E.S. L.D. A.L.B.B. O.A. F.G.D.F. and S.T.F analyzed data. J.M.S. S.A.L. V.F.P. M.A.M.P. A.L.E. A. Salvetti, A. Sebollela, and W.L.K. contributed reagents, materials, and analysis tools. M.C.S. J.T.S.F. L.E.S. A.L.E. A. Salvetti, A. Sebollela, B.M.L, O.A. W.L.K. F.G.D.F. D.A.J. and S.T.F. analyzed and discussed the results. M.C.S. W.L.K. and S.T.F. wrote the manuscript with contributions from other authors. A patent application covering the use of AAV-NUsc1 in Alzheimer's disease has been filed with the USPTO (16/820,269, pending) by Northwestern University with S.T.F. W.L.K. D.A.J. A. Sebollela, and M.C.S. as named inventors.

المصدر: Molecular Therapy
Molecular Therapy, 2023, 31 (2), pp.409-419. ⟨10.1016/j.ymthe.2022.11.002⟩

مصطلحات موضوعية: memory, NUsc1, Pharmacology, AβOs, [SDV]Life Sciences [q-bio], Drug Discovery, Genetics, Molecular Medicine, AAV, Alzheimer's disease, immuno-gene therapy, Molecular Biology, scFv

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bca9d98fc497066c6d6b0c8d4c6480e2
https://pubmed.ncbi.nlm.nih.gov/36369741

المؤلفون: André L. B. Bitencourt, Raquel M. Campos, Erika N. Cline, William L. Klein, Adriano Sebollela

المصدر: International Journal of Molecular Sciences, Vol 21, Iss 23, p 8920 (2020)

مصطلحات موضوعية: antibody fragments, single chain, amyloid, oligomer, neurotoxicity, NUsc1, Biology (General), QH301-705.5, Chemistry, QD1-999

وصف الملف: electronic resource

Relation: https://www.mdpi.com/1422-0067/21/23/8920; https://doaj.org/toc/1661-6596; https://doaj.org/toc/1422-0067

URL الوصول: https://doaj.org/article/29f9f65aaf1b4f148236c7c48bbf8f09