المؤلفون: Moiani A; Cellectis S.A., 8 Rue de la Croix Jarry, Paris, France. arianna.moiani@cellectis.com., Letort G; Cellectis S.A., 8 Rue de la Croix Jarry, Paris, France., Lizot S; Cellectis S.A., 8 Rue de la Croix Jarry, Paris, France., Chalumeau A; Université Paris Cité, Imagine Institute, Laboratory of Chromatin and Gene Regulation During Development, INSERM UMR 1163, Paris, France., Foray C; Cellectis S.A., 8 Rue de la Croix Jarry, Paris, France., Felix T; Université Paris Cité, Imagine Institute, Laboratory of Chromatin and Gene Regulation During Development, INSERM UMR 1163, Paris, France., Le Clerre D; Cellectis S.A., 8 Rue de la Croix Jarry, Paris, France., Temburni-Blake S; Cellectis Inc., 430 East 29th Street, New York, NY, USA., Hong P; Cellectis Inc., 430 East 29th Street, New York, NY, USA., Leduc S; Cellectis S.A., 8 Rue de la Croix Jarry, Paris, France., Pinard N; Cellectis S.A., 8 Rue de la Croix Jarry, Paris, France., Marechal A; Cellectis S.A., 8 Rue de la Croix Jarry, Paris, France., Seclen E; Cellectis Inc., 430 East 29th Street, New York, NY, USA., Boyne A; Cellectis Inc., 430 East 29th Street, New York, NY, USA., Mayer L; Cellectis Inc., 430 East 29th Street, New York, NY, USA., Hong R; Cellectis Inc., 430 East 29th Street, New York, NY, USA., Pulicani S; Cellectis S.A., 8 Rue de la Croix Jarry, Paris, France., Galetto R; Cellectis S.A., 8 Rue de la Croix Jarry, Paris, France., Gouble A; Cellectis S.A., 8 Rue de la Croix Jarry, Paris, France., Cavazzana M; Biotherapy Clinical Investigation Center, Necker Children's Hospital, Assistance Publique Hopitaux de Paris, Paris, France.; Human Lymphohematopoiesis Laboratory, Imagine Institute, INSERM UMR1163, Paris Cité University, Paris, France.; Biotherapy Department, Necker Children's Hospital, Assistance Publique Hopitaux de Paris, Paris, France., Juillerat A; Cellectis Inc., 430 East 29th Street, New York, NY, USA., Miccio A; Université Paris Cité, Imagine Institute, Laboratory of Chromatin and Gene Regulation During Development, INSERM UMR 1163, Paris, France., Duclert A; Cellectis S.A., 8 Rue de la Croix Jarry, Paris, France., Duchateau P; Cellectis S.A., 8 Rue de la Croix Jarry, Paris, France., Valton J; Cellectis S.A., 8 Rue de la Croix Jarry, Paris, France. julien.valton@cellectis.com.

المصدر: Nature communications [Nat Commun] 2024 Jun 11; Vol. 15 (1), pp. 4965. Date of Electronic Publication: 2024 Jun 11.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Anemia, Sickle Cell*/therapy , Anemia, Sickle Cell*/genetics , Gene Editing*/methods , Hematopoietic Stem Cells*/metabolism , Genetic Therapy*/methods , Transcription Activator-Like Effector Nucleases*/metabolism , Transcription Activator-Like Effector Nucleases*/genetics, Animals ; Humans ; Female ; Mice ; Hematopoietic Stem Cell Transplantation ; beta-Globins/genetics ; Tumor Suppressor Protein p53/genetics ; Tumor Suppressor Protein p53/metabolism ; DNA Repair ; Mutation ; beta-Thalassemia/therapy ; beta-Thalassemia/genetics ; Disease Models, Animal ; Gene Transfer Techniques

المؤلفون: Seclen E; Cellectis, New York, NY 10016, USA., Jang JC; Cellectis, New York, NY 10016, USA., Lawal AO; Cellectis, New York, NY 10016, USA., Pulicani S; Cellectis, New York, NY 10016, USA., Boyne A; Cellectis, New York, NY 10016, USA., Tkach D; Cellectis, New York, NY 10016, USA., Juillerat A; Cellectis, New York, NY 10016, USA., Duchateau P; Cellectis, New York, NY 10016, USA., Valton J; Cellectis, New York, NY 10016, USA. Electronic address: julien.valton@cellectis.com.

المصدر: Molecular therapy : the journal of the American Society of Gene Therapy [Mol Ther] 2024 Jun 05; Vol. 32 (6), pp. 1643-1657. Date of Electronic Publication: 2024 Apr 06.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 100890581 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1525-0024 (Electronic) Linking ISSN: 15250016 NLM ISO Abbreviation: Mol Ther Subsets: MEDLINE

مواضيع طبية MeSH: Gene Editing*/methods , Transgenes* , Hematopoietic Stem Cells*/metabolism , Introns* , Myeloid Cells*/metabolism , Transcription Activator-Like Effector Nucleases*/genetics , Transcription Activator-Like Effector Nucleases*/metabolism, Animals ; Mice ; Humans ; Cell Differentiation/genetics ; Genetic Therapy/methods ; Iduronidase/genetics ; Iduronidase/metabolism ; Green Fluorescent Proteins/genetics ; Green Fluorescent Proteins/metabolism ; Gene Expression ; Cell Lineage/genetics ; CD11b Antigen/genetics ; CD11b Antigen/metabolism ; Hematopoietic Stem Cell Transplantation/methods ; Mucopolysaccharidosis I/therapy ; Mucopolysaccharidosis I/genetics

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المؤلفون: Seclen E; Department of Molecular Microbiology and Immunology, Keck School of Medicine, University of Southern California, Los Angeles, USA.

المصدر: AIDS reviews [AIDS Rev] 2019; Vol. 21 (2), pp. 109-111.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Permanyer Publications Country of Publication: Spain NLM ID: 101134876 Publication Model: Print Cited Medium: Internet ISSN: 1698-6997 (Electronic) Linking ISSN: 11396121 NLM ISO Abbreviation: AIDS Rev Subsets: MEDLINE

مواضيع طبية MeSH: Clustered Regularly Interspaced Short Palindromic Repeats* , Virus Latency*, CRISPR-Associated Protein 9/*metabolism , Gene Editing/*methods , Genetic Therapy/*methods , HIV Infections/*therapy, HIV Infections/virology ; Humans

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المؤلفون: Canny MD; The Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada., Moatti N; The Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada., Wan LCK; The Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada.; Department of Molecular Genetics, University of Toronto, Ontario, Canada., Fradet-Turcotte A; The Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada., Krasner D; Department of Molecular Microbiology and Immunology, Keck School of Medicine, University of Southern California, Los Angeles, California, USA., Mateos-Gomez PA; Skirball Institute of Biomolecular Medicine, Department of Cell Biology, NYU Langone Medical Center, New York, New York, USA., Zimmermann M; The Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada., Orthwein A; The Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada., Juang YC; The Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada., Zhang W; The Donnelly Centre for Cellular and Biomolecular Research, Banting and Best Department of Medical Research, University of Toronto, Ontario, Canada., Noordermeer SM; The Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada., Seclen E; Department of Molecular Microbiology and Immunology, Keck School of Medicine, University of Southern California, Los Angeles, California, USA., Wilson MD; The Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada., Vorobyov A; The Donnelly Centre for Cellular and Biomolecular Research, Banting and Best Department of Medical Research, University of Toronto, Ontario, Canada., Munro M; The Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada., Ernst A; The Donnelly Centre for Cellular and Biomolecular Research, Banting and Best Department of Medical Research, University of Toronto, Ontario, Canada., Ng TF; The Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada.; Department of Molecular Genetics, University of Toronto, Ontario, Canada., Cho T; The Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada.; Department of Molecular Genetics, University of Toronto, Ontario, Canada., Cannon PM; Department of Molecular Microbiology and Immunology, Keck School of Medicine, University of Southern California, Los Angeles, California, USA., Sidhu SS; Department of Molecular Genetics, University of Toronto, Ontario, Canada.; The Donnelly Centre for Cellular and Biomolecular Research, Banting and Best Department of Medical Research, University of Toronto, Ontario, Canada., Sicheri F; The Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada.; Department of Molecular Genetics, University of Toronto, Ontario, Canada., Durocher D; The Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada.; Department of Molecular Genetics, University of Toronto, Ontario, Canada.

المصدر: Nature biotechnology [Nat Biotechnol] 2018 Jan; Vol. 36 (1), pp. 95-102. Date of Electronic Publication: 2017 Nov 27.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature America Publishing Country of Publication: United States NLM ID: 9604648 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-1696 (Electronic) Linking ISSN: 10870156 NLM ISO Abbreviation: Nat Biotechnol Subsets: MEDLINE

مواضيع طبية MeSH: Gene Editing*, CRISPR-Cas Systems/*genetics , Tumor Suppressor p53-Binding Protein 1/*genetics, Animals ; DNA Damage/genetics ; DNA End-Joining Repair/genetics ; DNA Repair/genetics ; Gene Expression Regulation/genetics ; Humans ; Mice ; Recombinational DNA Repair/genetics ; Tumor Suppressor p53-Binding Protein 1/antagonists & inhibitors

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المؤلفون: Exline CM; Department of Molecular Microbiology and Immunology, Keck School of Medicine, University of Southern California, 2011 Zonal Avenue, HMR 502, Los Angeles, CA, 90033, USA. colinexline@gmail.com., Yang SJ; Department of Molecular Microbiology and Immunology, Keck School of Medicine, University of Southern California, 2011 Zonal Avenue, HMR 502, Los Angeles, CA, 90033, USA. suyang@usc.edu., Haworth KG; Department of Molecular Microbiology and Immunology, Keck School of Medicine, University of Southern California, 2011 Zonal Avenue, HMR 502, Los Angeles, CA, 90033, USA. khaworth@fredhutch.org., Rengarajan S; Department of Molecular Microbiology and Immunology, Keck School of Medicine, University of Southern California, 2011 Zonal Avenue, HMR 502, Los Angeles, CA, 90033, USA. srinivas.rengarajan@gmail.com., Lopez LA; Department of Molecular Microbiology and Immunology, Keck School of Medicine, University of Southern California, 2011 Zonal Avenue, HMR 502, Los Angeles, CA, 90033, USA. lalopezphd@gmail.com., Droniou ME; Department of Molecular Microbiology and Immunology, Keck School of Medicine, University of Southern California, 2011 Zonal Avenue, HMR 502, Los Angeles, CA, 90033, USA. magali.droniou@stilla.fr., Seclen E; Department of Molecular Microbiology and Immunology, Keck School of Medicine, University of Southern California, 2011 Zonal Avenue, HMR 502, Los Angeles, CA, 90033, USA. seclen@usc.edu., Cannon PM; Department of Molecular Microbiology and Immunology, Keck School of Medicine, University of Southern California, 2011 Zonal Avenue, HMR 502, Los Angeles, CA, 90033, USA. pcannon@usc.edu.

المصدر: Retrovirology [Retrovirology] 2015 Aug 07; Vol. 12, pp. 67. Date of Electronic Publication: 2015 Aug 07.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 101216893 Publication Model: Electronic Cited Medium: Internet ISSN: 1742-4690 (Electronic) Linking ISSN: 17424690 NLM ISO Abbreviation: Retrovirology Subsets: MEDLINE

مواضيع طبية MeSH: Antigens, CD/*chemistry , Antigens, CD/*metabolism , HIV-2/*genetics , HIV-2/*metabolism , Host-Pathogen Interactions/*immunology , env Gene Products, Human Immunodeficiency Virus/*chemistry , env Gene Products, Human Immunodeficiency Virus/*metabolism, Amino Acid Motifs ; GPI-Linked Proteins/antagonists & inhibitors ; GPI-Linked Proteins/chemistry ; GPI-Linked Proteins/metabolism ; HEK293 Cells ; HIV-2/immunology ; Humans ; Mutation ; Protein Interaction Domains and Motifs ; Viral Regulatory and Accessory Proteins/metabolism ; Virion ; Virus Replication ; env Gene Products, Human Immunodeficiency Virus/genetics

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المؤلفون: Labarga P; Department of Infectious Diseases, Hospital Carlos III, Madrid, Spain., Medrano J, Seclen E, Poveda E, Rodriguez-Novoa S, Morello J, de Mendoza C, Vispo E, Soriano V

المصدر: AIDS (London, England) [AIDS] 2010 Mar 13; Vol. 24 (5), pp. 777-9.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Lippincott Williams & Wilkins Country of Publication: England NLM ID: 8710219 Publication Model: Print Cited Medium: Internet ISSN: 1473-5571 (Electronic) Linking ISSN: 02699370 NLM ISO Abbreviation: AIDS Subsets: MEDLINE

مواضيع طبية MeSH: Adenine/*analogs & derivatives , Anti-HIV Agents/*administration & dosage , Deoxycytidine/*analogs & derivatives , HIV Infections/*drug therapy , Nevirapine/*administration & dosage , Organophosphonates/*administration & dosage, Adenine/administration & dosage ; Adult ; Deoxycytidine/administration & dosage ; Drug Therapy, Combination ; Emtricitabine ; Female ; Humans ; Male ; RNA, Viral ; Tenofovir ; Treatment Outcome ; Viral Load