المؤلفون: Graboski AL; Department of Pharmacology, University of North Carolina Chapel Hill North Carolina USA., Simpson JB; Department of Chemistry, University of North Carolina Chapel Hill North Carolina USA redinbo@unc.edu., Pellock SJ; Department of Chemistry, University of North Carolina Chapel Hill North Carolina USA redinbo@unc.edu., Mehta N; Center for Integrative Chemical Biology and Drug Discovery, Division of Chemical Biology and Medicinal Chemistry, UNC Eshelman School of Pharmacy, University of North Carolina Chapel Hill North Carolina USA., Creekmore BC; Department of Chemistry, University of North Carolina Chapel Hill North Carolina USA redinbo@unc.edu., Ariyarathna Y; Center for Integrative Chemical Biology and Drug Discovery, Division of Chemical Biology and Medicinal Chemistry, UNC Eshelman School of Pharmacy, University of North Carolina Chapel Hill North Carolina USA., Bhatt AP; Division of Gastroenterology and Hepatology, Department of Medicine, Center for Gastrointestinal Biology and Disease, and the Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill Chapel Hill NC USA., Jariwala PB; Department of Chemistry, University of North Carolina Chapel Hill North Carolina USA redinbo@unc.edu., Sekela JJ; Department of Chemistry, University of North Carolina Chapel Hill North Carolina USA redinbo@unc.edu., Kowalewski ME; Department of Biochemistry and Biophysics, University of North Carolina Chapel Hill North Carolina USA., Barker NK; UNC Proteomics Core Facility, Department of Pharmacology, University of North Carolina at Chapel Hill Chapel Hill NC USA., Mordant AL; UNC Proteomics Core Facility, Department of Pharmacology, University of North Carolina at Chapel Hill Chapel Hill NC USA., Borlandelli VB; Department of Bio-organic Synthesis, Leiden Institute of Chemistry, Leiden University Leiden The Netherlands., Overkleeft H; Department of Bio-organic Synthesis, Leiden Institute of Chemistry, Leiden University Leiden The Netherlands., Herring LE; UNC Proteomics Core Facility, Department of Pharmacology, University of North Carolina at Chapel Hill Chapel Hill NC USA., Jin J; Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai New York NY USA., I James L; Center for Integrative Chemical Biology and Drug Discovery, Division of Chemical Biology and Medicinal Chemistry, UNC Eshelman School of Pharmacy, University of North Carolina Chapel Hill North Carolina USA., Redinbo MR; Department of Chemistry, University of North Carolina Chapel Hill North Carolina USA redinbo@unc.edu.; Department of Biochemistry and Biophysics, University of North Carolina Chapel Hill North Carolina USA.

المصدر: RSC chemical biology [RSC Chem Biol] 2024 Jul 16; Vol. 5 (9), pp. 853-865. Date of Electronic Publication: 2024 Jul 16 (Print Publication: 2024).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 101768727 Publication Model: eCollection Cited Medium: Internet ISSN: 2633-0679 (Electronic) Linking ISSN: 26330679 NLM ISO Abbreviation: RSC Chem Biol Subsets: PubMed not MEDLINE

المؤلفون: Simpson JB; Department of Chemistry, University of North Carolina, Chapel Hill, NC, USA., Walker ME; Department of Chemistry, University of North Carolina, Chapel Hill, NC, USA., Sekela JJ; Department of Chemistry, University of North Carolina, Chapel Hill, NC, USA., Ivey SM; Department of Chemistry, University of North Carolina, Chapel Hill, NC, USA., Jariwala PB; Department of Chemistry, University of North Carolina, Chapel Hill, NC, USA., Storch CM; Department of Chemistry, University of North Carolina, Chapel Hill, NC, USA., Kowalewski ME; Department of Biochemistry and Biophysics, University of North Carolina, Chapel Hill, NC, USA., Graboski AL; Department of Pharmacology, University of North Carolina, Chapel Hill, NC, USA., Lietzan AD; Division of Oral and Craniofacial Health Sciences, Adams School of Dentistry, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Walton WG; Department of Chemistry, University of North Carolina, Chapel Hill, NC, USA., Davis KA; Department of Biochemistry and Biophysics, University of North Carolina, Chapel Hill, NC, USA., Cloer EW; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Borlandelli V; Department of Bioorganic Synthesis, Leiden Institute of Chemistry, Leiden University, Leiden, the Netherlands., Hsiao YC; Department of Environmental Sciences and Engineering, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Roberts LR; Exploratory Science Center, Merck & Co., Inc., Cambridge, MA 02141, USA., Perlman DH; Exploratory Science Center, Merck & Co., Inc., Cambridge, MA 02141, USA., Liang X; Exploratory Science Center, Merck & Co., Inc., Cambridge, MA 02141, USA., Overkleeft HS; Department of Bioorganic Synthesis, Leiden Institute of Chemistry, Leiden University, Leiden, the Netherlands., Bhatt AP; Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA; Division of Gastroenterology and Hepatology, Department of Medicine, Center for Gastrointestinal Biology and Disease, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Lu K; Department of Environmental Sciences and Engineering, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Redinbo MR; Department of Chemistry, University of North Carolina, Chapel Hill, NC, USA; Department of Biochemistry and Biophysics, University of North Carolina, Chapel Hill, NC, USA. Electronic address: redinbo@unc.edu.

المصدر: Cell host & microbe [Cell Host Microbe] 2024 Jun 12; Vol. 32 (6), pp. 925-944.e10. Date of Electronic Publication: 2024 May 15.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101302316 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1934-6069 (Electronic) Linking ISSN: 19313128 NLM ISO Abbreviation: Cell Host Microbe Subsets: MEDLINE

مواضيع طبية MeSH: Homeostasis* , Gastrointestinal Microbiome*/drug effects , Glucuronidase*/metabolism, Animals ; Mice ; Mice, Inbred C57BL ; Serotonin/metabolism ; Glucuronides/metabolism ; Humans ; Intestines/microbiology ; Male ; Germ-Free Life

المؤلفون: Simpson JB; Department of Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Sekela JJ; Department of Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Carry BS; Department of Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Beaty V; Department of Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Patel S; Department of Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Redinbo MR; Department of Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Department of Biochemistry and Biophysics, Department of Microbiology and Immunology, and the Integrated Program for Biological and Genome Sciences, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.

المصدر: Gut microbes [Gut Microbes] 2023 Jan-Dec; Vol. 15 (1), pp. 2203963.

نوع المنشور: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101495343 Publication Model: Print Cited Medium: Internet ISSN: 1949-0984 (Electronic) Linking ISSN: 19490976 NLM ISO Abbreviation: Gut Microbes Subsets: MEDLINE

مواضيع طبية MeSH: Gastrointestinal Microbiome* , Prodrugs* , Amlodipine Besylate, Olmesartan Medoxomil Drug Combination* , Crohn Disease* , Colitis, Ulcerative* , Inflammatory Bowel Diseases*/drug therapy, Humans ; Mesalamine/therapeutic use

المؤلفون: Simpson JB; Department of Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Sekela JJ; Department of Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Graboski AL; Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Borlandelli VB; Department of Bioorganic Synthesis, Leiden Institute of Chemistry, Leiden University, Leiden, The Netherlands., Bivins MM; Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Barker NK; UNC Proteomics Core Facility, Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Sorgen AA; Department of Biological Sciences, University of North Carolina at Charlotte, Charlotte, NC, USA., Mordant AL; UNC Proteomics Core Facility, Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Johnson RL; Center for Integrative Chemical Biology and Drug Discovery, Division of Chemical Biology and Medicinal Chemistry, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Bhatt AP; Division of Gastroenterology and Hepatology, Department of Medicine, Center for Gastrointestinal Biology and Disease, and the Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Fodor AA; Department of Bioinformatics and Genomics, University of North Carolina at Charlotte, Charlotte, NC, USA., Herring LE; UNC Proteomics Core Facility, Department of Pharmacology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Overkleeft H; Department of Bioorganic Synthesis, Leiden Institute of Chemistry, Leiden University, Leiden, The Netherlands., Lee JR; Department of Medicine, Division of Nephrology and Hypertension, New York, New York, USA., Redinbo MR; Department of Chemistry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Department of Biochemistry and Biophysics, Department of Microbiology and Immunology, and the Institute for Biological and Genome Sciences, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.

المصدر: Gut microbes [Gut Microbes] 2022 Jan-Dec; Vol. 14 (1), pp. 2107289.

نوع المنشور: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Taylor & Francis Country of Publication: United States NLM ID: 101495343 Publication Model: Print Cited Medium: Internet ISSN: 1949-0984 (Electronic) Linking ISSN: 19490976 NLM ISO Abbreviation: Gut Microbes Subsets: MEDLINE

مواضيع طبية MeSH: Gastrointestinal Microbiome*/physiology, Flavin Mononucleotide ; Glucuronides ; Humans ; Immunosuppressive Agents ; Mycophenolic Acid/therapeutic use ; Proteomics