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1
المؤلفون: Harish Shankaran, Abhishek G. Sathe, Jennifer C. Sasaki, Aixiang Xue, Per E. Andrén, Selvi Pradeepan, Anna Nilsson, Richard J. A. Goodwin, Natalie Keirstead, Anshul Gupta, Richard T. Gallagher, John G. Swales
المصدر: Chemical Research in Toxicology. 28:1823-1830
مصطلحات موضوعية: Male, Spectrometry, Mass, Electrospray Ionization, Chemistry, medicine.drug_class, Polymyxin B1, Metabolite, Polymyxin, General Medicine, Pharmacology, Kidney, Toxicology, Mass spectrometry imaging, Rats, Nephrotoxicity, chemistry.chemical_compound, Colistin, medicine, Animals, lipids (amino acids, peptides, and proteins), Polymyxins, Rats, Wistar, Drug metabolism, Polymyxin B, Chromatography, Liquid, medicine.drug
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2
المؤلفون: Selvi Pradeepan, Chet Metcalf, Brendan F. Boyce, Shuangying Liu, Manfred Weigele, Surinder S. Narula, Regine S. Bohacek, Lianping Xing, Raji Sundaramoorthi, Jeff Keats, Julie Bogus, Jennifer Saltmarsh, Yihan Wang, Scott Wardwell, Mary K. Ram, David C. Dalgarno, John Iuliucci, Susan Adams, Guru Paramanathan, Shuenn Liou, Marie Rose van Schravendijk, Anne Dilauro, Sonya Roeloffzen, T. Keenan, William C. Shakespeare, Tomi K. Sawyer
المصدر: Chemical Biology & Drug Design. 71:97-105
مصطلحات موضوعية: Organophosphonates, Crystallography, X-Ray, Biochemistry, Bone resorption, Inhibitory Concentration 50, Structure-Activity Relationship, Drug Delivery Systems, In vivo, Drug Discovery, Humans, Structure–activity relationship, Bone Resorption, Enzyme Inhibitors, Purine metabolism, IC50, Pharmacology, Tyrosine-protein kinase CSK, Molecular Structure, Chemistry, Adenine, Organic Chemistry, Phosphinic Acids, src-Family Kinases, Parathyroid Hormone, Purines, Hypercalcemia, Osteoporosis, Molecular Medicine, Tyrosine kinase, Proto-oncogene tyrosine-protein kinase Src
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3
المؤلفون: Selvi Pradeepan, Taylor Merry, Shelia Violette, Surinder S. Narula, Noriyuki Kawahata, Yihan Wang, Tomi K. Sawyer, David C. Dalgarno, Susan Adams, George P. Luke, Terence P. Keenan, Regine S. Bohacek, Wei Guan, Marie Rose van Schravendijk, Raji Sundaramoorthi, Jeffrey A. Keats, Mary K. Ram, Evelyn G. Corpuz, Chi B. Vu, Manfred Weigele, Chester A. Metcalf, Shuenn Liou, William C. Shakespeare
المصدر: Bioorganic & Medicinal Chemistry Letters. 13:3071-3074
مصطلحات موضوعية: Clinical Biochemistry, Cell, Osteoclasts, Pharmaceutical Science, Pyrimidinones, Biochemistry, Inhibitory Concentration 50, Structure-Activity Relationship, Drug Discovery, medicine, Animals, Computer Simulation, Bone Resorption, Enzyme Inhibitors, Molecular Biology, chemistry.chemical_classification, biology, Organic Chemistry, In vitro, Durapatite, src-Family Kinases, Enzyme, medicine.anatomical_structure, chemistry, Enzyme inhibitor, Drug Design, Dentin, biology.protein, Molecular Medicine, Phosphorylation, Rabbits, Bone Diseases, Signal transduction, Tyrosine kinase, Proto-oncogene tyrosine-protein kinase Src
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4
المؤلفون: Taylor Merry, Selvi Pradeepan, Raji Sundaramoorthi, Virginia A. Jacobsen, Mayumi Uesugi, Vaibhav Varkhedkar, Chi B. Vu, Chester A. Metcalf, Jeremy Green, Dennis A. Holt, Edgardo Laborde, Karina J. Macek, Yinka Green
المصدر: Tetrahedron Letters. 39:3435-3438
مصطلحات موضوعية: chemistry.chemical_compound, chemistry, Yield (chemistry), Phase (matter), Organic Chemistry, Drug Discovery, Phenyl phosphate, Phenol, Organic chemistry, Phosphate, Biochemistry
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5
المؤلفون: Peter Doig, Sameer Kawatkar, P. Ann Boriack-Sjodin, James T. Loch, Linda G. Otterson, Amy Kutschke, Selvi Pradeepan, Gabriel Martínez-Botella, Nelson B. Olivier, Joseph V. Newman, Satenig Guler, Oluyinka Green, Jacques Dumas, Andrew R. McKenzie, Eric Gangl, John Breen, Swati Prasad, Beth Andrews, Martin F. Hentemann, Diane Joseph-McCarthy, Thomas A. Keating
المصدر: ACS chemical biology. 7(11)
مصطلحات موضوعية: Models, Molecular, Staphylococcus aureus, medicine.drug_class, Antibiotics, Biology, medicine.disease_cause, Gram-Positive Bacteria, Biochemistry, Thymidylate kinase, chemistry.chemical_compound, In vivo, medicine, Humans, Nucleotide, Gram-Positive Bacterial Infections, chemistry.chemical_classification, Thymidine monophosphate, DNA synthesis, Kinase, General Medicine, Staphylococcal Infections, Anti-Bacterial Agents, chemistry, Molecular Medicine, Nucleoside-Phosphate Kinase, Enterococcus
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6
المؤلفون: Chester A. Metcalf, Ukti Mani, Shiela M. Violette, Tomi K. Sawyer, Susan Adams, Yihan Wang, Terence P. Keenan, Regine S. Bohacek, Marie Rose van Schravendijk, Mary K. Ram, David C. Dalgarno, Selvi Pradeepan, Raji Sundaramoorthi, William C. Shakespeare, Jeffrey A. Keats, Surinder S. Narula, Chad Haraldson, Manfred Weigele, Shuenn Liou
المصدر: Bioorganicmedicinal chemistry letters. 13(18)
مصطلحات موضوعية: Purine, Clinical Biochemistry, Pharmaceutical Science, Biochemistry, Receptor tyrosine kinase, chemistry.chemical_compound, Inhibitory Concentration 50, Structure-Activity Relationship, Adenosine Triphosphate, Drug Delivery Systems, Drug Discovery, Animals, Humans, Enzyme Inhibitors, Purine metabolism, Molecular Biology, biology, Kinase, Organic Chemistry, Durapatite, src-Family Kinases, chemistry, Purines, Drug Design, biology.protein, Molecular Medicine, Phosphorylation, Signal transduction, Bone Diseases, Tyrosine kinase, Proto-oncogene tyrosine-protein kinase Src
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7
المؤلفون: Chad Haraldson, Taylor Merry, Tomi K. Sawyer, Karin Stebbins, Marcos Hatada, Franklin Cerasoli, Surinder S. Narula, David C. Dalgarno, William C. Shakespeare, Marie Rose van Schravendijk, Jay Herson, Selvi Pradeepan, John Iuliucci, Manfred Weigele, Raji Sundaramoorthi, Xiaode Lu, Jeremy Smith, Mihai Azimioara, Susan Adams, Chester A. Metcalf, Shelia Violette, Chi B. Vu, Regine S. Bohacek, Michael Yang, Wei Guan, Catherine Bartlett
مصطلحات موضوعية: Models, Molecular, Protein Conformation, Proto-Oncogene Proteins pp60(c-src), Osteoclasts, Crystallography, X-Ray, Bone and Bones, Citric Acid, Substrate Specificity, src Homology Domains, Inhibitory Concentration 50, Structure-Activity Relationship, Protein structure, Osteoclast, In vivo, medicine, Structure–activity relationship, Animals, Binding site, Bone Resorption, Rats, Wistar, Phosphotyrosine, Parathyroidectomy, Multidisciplinary, Binding Sites, Diphosphonates, Chemistry, Phosphopeptide, Molecular Mimicry, Rats, medicine.anatomical_structure, Biochemistry, Amino Acid Substitution, Lymphocyte Specific Protein Tyrosine Kinase p56(lck), Parathyroid Hormone, Drug Design, Physical Sciences, Dentin, Female, Adsorption, Hydroxyapatites, Rabbits, Tyrosine kinase, Proto-oncogene tyrosine-protein kinase Src
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4c5b835f12945cdcdbb7f6a31d14980
https://europepmc.org/articles/PMC16871/ -
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المؤلفون: Selvi Pradeepan, Chi B. Vu, Tomi K. Sawyer, Shelia Violette, van Schravendijk Mr, Ian A. MacNeil, Catherine Bartlett, Mary K. Ram, Botfield Mc, Charles J. Eyermann, Berkley A. Lynch, Taylor Merry, Evelyn G. Corpuz, Regine S. Bohacek
المصدر: Journal of medicinal chemistry. 42(20)
مصطلحات موضوعية: Models, Molecular, Enzyme Precursors, Oxadiazoles, ZAP-70 Protein-Tyrosine Kinase, biology, Tetrapeptide, Stereochemistry, Chemistry, Intracellular Signaling Peptides and Proteins, Syk, Protein-Tyrosine Kinases, SH2 domain, Receptor tyrosine kinase, SH3 domain, src Homology Domains, Structure-Activity Relationship, Biochemistry, Drug Discovery, biology.protein, Molecular Medicine, Syk Kinase, GRB2, Enzyme Inhibitors, Tyrosine kinase, Proto-oncogene tyrosine-protein kinase Src