المؤلفون: Gao S; Department of Anesthesiology, Zhongshan Hospital, Fudan University, Shanghai 200032, China.; Shanghai Key Laboratory of Perioperative Stress and Protection, Shanghai 200032, China., Shen R; Shanghai Laboratory Animal Research Center, Shanghai 201203, China., Li J; Institutes of Brain Science, State Key Laboratory of Medical Neurobiology and Ministry of Education (MOE) Frontiers Center for Brain Science, Shanghai 200032, China.; Department of Neurobiology, Zhongshan Hospital, Fudan University, Shanghai 200032, China., Jiang Y; Department of Anesthesiology, Zhongshan Hospital, Fudan University, Shanghai 200032, China.; Shanghai Key Laboratory of Perioperative Stress and Protection, Shanghai 200032, China., Sun H; Department of Anesthesiology, Zhongshan Hospital, Fudan University, Shanghai 200032, China.; Shanghai Key Laboratory of Perioperative Stress and Protection, Shanghai 200032, China., Wu X; Department of Anesthesiology, Zhongshan Hospital, Fudan University, Shanghai 200032, China.; Shanghai Key Laboratory of Perioperative Stress and Protection, Shanghai 200032, China., Li X; Department of Anesthesiology, Zhongshan Hospital, Fudan University, Shanghai 200032, China.; Shanghai Key Laboratory of Perioperative Stress and Protection, Shanghai 200032, China., Miao C; Department of Anesthesiology, Zhongshan Hospital, Fudan University, Shanghai 200032, China.; Shanghai Key Laboratory of Perioperative Stress and Protection, Shanghai 200032, China., He M; Institutes of Brain Science, State Key Laboratory of Medical Neurobiology and Ministry of Education (MOE) Frontiers Center for Brain Science, Shanghai 200032, China.; Department of Neurobiology, Zhongshan Hospital, Fudan University, Shanghai 200032, China., Wang J; Department of Integrative Medicine and Neurobiology, School of Basic Medical Science, Shanghai Key Laboratory of Acupuncture Mechanism and Acupoint Function, Fudan University, Shanghai 200032, China., Chen W; Department of Anesthesiology, Zhongshan Hospital, Fudan University, Shanghai 200032, China.; Shanghai Key Laboratory of Perioperative Stress and Protection, Shanghai 200032, China.; Department of Anesthesiology, Shanghai Geriatric Medical Center, Shanghai 201104, China.; Department of Anesthesiology, QingPu Branch of Zhongshan Hospital, Fudan University, Shanghai 201799, China.

المصدر: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2024 Sep 03; Vol. 121 (36), pp. e2410564121. Date of Electronic Publication: 2024 Aug 27.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

مواضيع طبية MeSH: Sepsis-Associated Encephalopathy*/metabolism , Sepsis-Associated Encephalopathy*/genetics , Cognitive Dysfunction*/metabolism , Cognitive Dysfunction*/genetics , RNA, Messenger*/metabolism , RNA, Messenger*/genetics, Animals ; Acetylation ; Mice ; Male ; Acetyltransferases/metabolism ; Acetyltransferases/genetics ; Neurons/metabolism ; Disease Models, Animal ; Mice, Inbred C57BL ; Sepsis/metabolism ; Sepsis/complications ; Sepsis/genetics ; Microglia/metabolism ; Hippocampus/metabolism ; Dentate Gyrus/metabolism

المؤلفون: Peng H; Department of Pediatric Intensive Care Unit, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, No. 318 Renmin Middle Road, Yuexiu District, Guangzhou, 510120, China.; Department of Intensive Care Medicine, Liuzhou Affiliated Guangzhou Women and Children's Medical Center, No. 50 Boyuan Avenue, Liudong New District, Yufeng District, Liuzhou, 545005, China., Liang Z; Department of Intensive Care Medicine, Liuzhou Affiliated Guangzhou Women and Children's Medical Center, No. 50 Boyuan Avenue, Liudong New District, Yufeng District, Liuzhou, 545005, China., Zhang S; Department of Intensive Care Medicine, Liuzhou Affiliated Guangzhou Women and Children's Medical Center, No. 50 Boyuan Avenue, Liudong New District, Yufeng District, Liuzhou, 545005, China., Yang Y; Department of Pediatric Intensive Care Unit, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, No. 318 Renmin Middle Road, Yuexiu District, Guangzhou, 510120, China. yangyiyu2019@126.com.

المصدر: BMC infectious diseases [BMC Infect Dis] 2024 Sep 02; Vol. 24 (1), pp. 902. Date of Electronic Publication: 2024 Sep 02.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 100968551 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2334 (Electronic) Linking ISSN: 14712334 NLM ISO Abbreviation: BMC Infect Dis Subsets: MEDLINE

مواضيع طبية MeSH: Arterial Pressure* , Hospital Mortality* , Sepsis-Associated Encephalopathy*/physiopathology , Sepsis-Associated Encephalopathy*/mortality , Sepsis-Associated Encephalopathy*/complications, Humans ; Retrospective Studies ; Female ; Male ; Middle Aged ; Aged ; Intensive Care Units/statistics & numerical data ; Sepsis/mortality ; Sepsis/complications

المؤلفون: Li N; Xi'an Key Laboratory of Innovative Drug Research for Heart Failure, Faculty of Life Sciences and Medicine, Northwest University, 229 Taibai North Road, Xi'an, 710069, China., Liao S; Xi'an Key Laboratory of Innovative Drug Research for Heart Failure, Faculty of Life Sciences and Medicine, Northwest University, 229 Taibai North Road, Xi'an, 710069, China., Liu L; Xi'an Key Laboratory of Innovative Drug Research for Heart Failure, Faculty of Life Sciences and Medicine, Northwest University, 229 Taibai North Road, Xi'an, 710069, China., Wang X; Department of Cardiovascular Surgery, The First Affiliated Hospital of Xi'an Jiaotong University, 277 Yanta West Road, Xi'an, 710061, China., Liang Z; Department of Cardiothoracic Surgery, The First Affiliated Hospital of Zhengzhou University, 1 Jianshe East, Zhengzhou, 450052, China., Liu X; Xi'an Key Laboratory of Innovative Drug Research for Heart Failure, Faculty of Life Sciences and Medicine, Northwest University, 229 Taibai North Road, Xi'an, 710069, China., Song Y; Xi'an Key Laboratory of Innovative Drug Research for Heart Failure, Faculty of Life Sciences and Medicine, Northwest University, 229 Taibai North Road, Xi'an, 710069, China., Zhao S; Xi'an Key Laboratory of Innovative Drug Research for Heart Failure, Faculty of Life Sciences and Medicine, Northwest University, 229 Taibai North Road, Xi'an, 710069, China., Wu X; Xi'an Key Laboratory of Innovative Drug Research for Heart Failure, Faculty of Life Sciences and Medicine, Northwest University, 229 Taibai North Road, Xi'an, 710069, China., Tian Y; Xi'an Key Laboratory of Innovative Drug Research for Heart Failure, Faculty of Life Sciences and Medicine, Northwest University, 229 Taibai North Road, Xi'an, 710069, China., Xu X; Department of Cardiovascular Surgery, Xijing Hospital, The Fourth Military Medical University, 127 Changle West Road, Xi'an, 710032, China., Yang Y; Xi'an Key Laboratory of Innovative Drug Research for Heart Failure, Faculty of Life Sciences and Medicine, Northwest University, 229 Taibai North Road, Xi'an, 710069, China. Electronic address: yang200214yy@nwu.edu.cn., Liu Q; Xi'an Key Laboratory of Innovative Drug Research for Heart Failure, Faculty of Life Sciences and Medicine, Northwest University, 229 Taibai North Road, Xi'an, 710069, China. Electronic address: lqiong@nwu.edu.cn.

المصدر: Free radical biology & medicine [Free Radic Biol Med] 2024 Aug 20; Vol. 221, pp. 203-214. Date of Electronic Publication: 2024 May 22.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Science Country of Publication: United States NLM ID: 8709159 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4596 (Electronic) Linking ISSN: 08915849 NLM ISO Abbreviation: Free Radic Biol Med Subsets: MEDLINE

مواضيع طبية MeSH: Endoplasmic Reticulum Stress*/drug effects , Coumarins*/pharmacology , Sepsis-Associated Encephalopathy*/drug therapy , Sepsis-Associated Encephalopathy*/metabolism , Sepsis-Associated Encephalopathy*/pathology , Benzofurans*/pharmacology, Animals ; Mice ; Male ; Lipopolysaccharides/toxicity ; Sepsis/drug therapy ; Sepsis/complications ; Sepsis/metabolism ; NLR Family, Pyrin Domain-Containing 3 Protein/metabolism ; NLR Family, Pyrin Domain-Containing 3 Protein/genetics ; Disease Models, Animal ; Reactive Oxygen Species/metabolism ; Tunicamycin/pharmacology ; Mice, Inbred C57BL

المؤلفون: Zhong H; Wuhan Jinyintan Hospital, Tongji Medical College of Huazhong University of Science and Technology, Wuhan Institute of Virology and Wuhan Jinyintan Hospital, Chinese Academy of Sciences, ,; Hubei Clinical Research Center for Infectious Diseases, ,; Wuhan Research Center for Communicable Disease Diagnosis and Treatment, Chinese Academy of Medical Sciences, ,; Joint Laboratory of Infectious Diseases and Health, Wuhan Institute of Virology and Wuhan Jinyintan Hospital, Chinese Academy of Sciences,., Liu T; Department of Ultrasound Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology,., Shang Y; Department of Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology,., Huang C; Wuhan Jinyintan Hospital, Tongji Medical College of Huazhong University of Science and Technology, Wuhan Institute of Virology and Wuhan Jinyintan Hospital, Chinese Academy of Sciences, ,; Hubei Clinical Research Center for Infectious Diseases, ,; Wuhan Research Center for Communicable Disease Diagnosis and Treatment, Chinese Academy of Medical Sciences, ,; Joint Laboratory of Infectious Diseases and Health, Wuhan Institute of Virology and Wuhan Jinyintan Hospital, Chinese Academy of Sciences, ,. Electronic address: 2020jy0003@hust.edu.cn., Pan S; Department of Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, ,. Electronic address: pan_shangwen@163.com.

المصدر: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2024 Aug; Vol. 177, pp. 117042. Date of Electronic Publication: 2024 Jul 14.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 8213295 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1950-6007 (Electronic) Linking ISSN: 07533322 NLM ISO Abbreviation: Biomed Pharmacother Subsets: MEDLINE

مواضيع طبية MeSH: NLR Family, Pyrin Domain-Containing 3 Protein*/metabolism , Sepsis-Associated Encephalopathy*/metabolism , Sepsis-Associated Encephalopathy*/drug therapy , Inflammasomes*/metabolism, Humans ; Animals ; Microglia/metabolism ; Microglia/drug effects ; Blood-Brain Barrier/metabolism ; Neuroinflammatory Diseases/drug therapy ; Neuroinflammatory Diseases/metabolism

المؤلفون: Yang Y; Department of Anesthesiology, Nanfang Hospital, Southern Medical University; The key Laboratory of Precision Anesthesia & perioperative Organ Protection, Guangzhou, Guangdong, 510515, China. Electronic address: yyang_hl2022@163.com., Ke J; Department of Anesthesiology, Nanfang Hospital, Southern Medical University; The key Laboratory of Precision Anesthesia & perioperative Organ Protection, Guangzhou, Guangdong, 510515, China. Electronic address: kjy3531@163.com., Cao Y; Department of Anesthesiology, Nanfang Hospital, Southern Medical University; The key Laboratory of Precision Anesthesia & perioperative Organ Protection, Guangzhou, Guangdong, 510515, China. Electronic address: cymz0423@163.com., Gao Y; Department of Anesthesiology, Nanfang Hospital, Southern Medical University; The key Laboratory of Precision Anesthesia & perioperative Organ Protection, Guangzhou, Guangdong, 510515, China. Electronic address: 18238698268@126.com., Lin C; Department of Anesthesiology, Nanfang Hospital, Southern Medical University; The key Laboratory of Precision Anesthesia & perioperative Organ Protection, Guangzhou, Guangdong, 510515, China. Electronic address: linchunshui2014@163.com.

المصدر: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2024 Aug; Vol. 177, pp. 117092. Date of Electronic Publication: 2024 Jul 07.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 8213295 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1950-6007 (Electronic) Linking ISSN: 07533322 NLM ISO Abbreviation: Biomed Pharmacother Subsets: MEDLINE

مواضيع طبية MeSH: Melatonin*/pharmacology , Sepsis-Associated Encephalopathy*/metabolism , Sepsis-Associated Encephalopathy*/drug therapy , AMP-Activated Protein Kinases*/metabolism , Microglia*/drug effects , Microglia*/metabolism , Mitophagy*/drug effects , Lipopolysaccharides*, Animals ; Mice ; Male ; Mice, Inbred C57BL ; Protein Kinases/metabolism ; Disease Models, Animal ; Sepsis/complications ; Sepsis/metabolism ; Sepsis/drug therapy ; Cell Line ; Cell Polarity/drug effects ; Neuroinflammatory Diseases/drug therapy ; Neuroinflammatory Diseases/metabolism

المؤلفون: Cui Q; Department of Critical Care Medicine of the Third Affiliated Hospital (The First People's Hospital of Zunyi), Zunyi Medical University, Zunyi, China., Qin N; Department of Critical Care Medicine of the Third Affiliated Hospital (The First People's Hospital of Zunyi), Zunyi Medical University, Zunyi, China., Zhang Y; Department of Critical Care Medicine of the Third Affiliated Hospital (The First People's Hospital of Zunyi), Zunyi Medical University, Zunyi, China., Miao Y; Department of Critical Care Medicine of the Third Affiliated Hospital (The First People's Hospital of Zunyi), Zunyi Medical University, Zunyi, China., Xie L; Department of Critical Care Medicine of the Third Affiliated Hospital (The First People's Hospital of Zunyi), Zunyi Medical University, Zunyi, China., Ma X; Department of Critical Care Medicine of the Third Affiliated Hospital (The First People's Hospital of Zunyi), Zunyi Medical University, Zunyi, China., Zhang Z; Department of Anesthesiology, Duke University Medical Center, Durham, North Carolina, USA., Xie P; Department of Critical Care Medicine of the Third Affiliated Hospital (The First People's Hospital of Zunyi), Zunyi Medical University, Zunyi, China.

المصدر: Biotechnology and applied biochemistry [Biotechnol Appl Biochem] 2024 Aug; Vol. 71 (4), pp. 701-711. Date of Electronic Publication: 2024 Feb 26.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Wiley-Blackwell Country of Publication: United States NLM ID: 8609465 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1470-8744 (Electronic) Linking ISSN: 08854513 NLM ISO Abbreviation: Biotechnol Appl Biochem Subsets: MEDLINE

مواضيع طبية MeSH: Annexin A1*/metabolism , Annexin A1*/pharmacology , Rats, Sprague-Dawley* , Neuroprotective Agents*/pharmacology , Sepsis-Associated Encephalopathy*/drug therapy , Sepsis-Associated Encephalopathy*/metabolism , Sepsis-Associated Encephalopathy*/pathology, Animals ; Rats ; Male ; Reactive Oxygen Species/metabolism ; Apoptosis/drug effects ; PPAR gamma/metabolism ; Membrane Potential, Mitochondrial/drug effects

المؤلفون: Zhang Q; Department of Emergency and Critical Care Medicine, The Second Hospital of Jilin University, NO.218 Ziqiang Street, Changchun 130041, China., Lu C; Department of Anesthesiology, The Second Hospital of Jilin University, NO.218 Ziqiang Street, Changchun 130041, China., Fan W; Department of Emergency and Critical Care Medicine, The Second Hospital of Jilin University, NO.218 Ziqiang Street, Changchun 130041, China., Yin Y; Department of Emergency and Critical Care Medicine, The Second Hospital of Jilin University, NO.218 Ziqiang Street, Changchun 130041, China. Electronic address: yinyj@jlu.edu.cn.

المصدر: Cytokine [Cytokine] 2024 Aug; Vol. 180, pp. 156609. Date of Electronic Publication: 2024 May 22.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Science Ltd Country of Publication: England NLM ID: 9005353 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-0023 (Electronic) Linking ISSN: 10434666 NLM ISO Abbreviation: Cytokine Subsets: MEDLINE

مواضيع طبية MeSH: Sepsis-Associated Encephalopathy*/genetics , Sepsis-Associated Encephalopathy*/metabolism , Protein Interaction Maps*/genetics, Humans ; Databases, Genetic ; Gene Expression Profiling ; Gene Regulatory Networks ; Hippocampus/metabolism ; Signal Transduction/genetics ; Transcriptome/genetics ; Animals ; Sepsis/genetics ; Sepsis/metabolism

المؤلفون: Grünewald B; Center for Sepsis Control and Care, Jena University Hospital, Am Klinikum 1, 07747 Jena, Germany; Section Translational Neuroimmunology, Department of Neurology, Jena University Hospital, Am Klinikum 1, 07747 Jena, Germany; Institute of Pathophysiology and Focus Program Translational Neuroscience (FTN), University Medical Center of the Johannes Gutenberg University Mainz, 55131 Mainz, Germany., Wickel J; Center for Sepsis Control and Care, Jena University Hospital, Am Klinikum 1, 07747 Jena, Germany; Section Translational Neuroimmunology, Department of Neurology, Jena University Hospital, Am Klinikum 1, 07747 Jena, Germany., Hahn N; Center for Sepsis Control and Care, Jena University Hospital, Am Klinikum 1, 07747 Jena, Germany; Section Translational Neuroimmunology, Department of Neurology, Jena University Hospital, Am Klinikum 1, 07747 Jena, Germany., Rahmati V; Section Translational Neuroimmunology, Department of Neurology, Jena University Hospital, Am Klinikum 1, 07747 Jena, Germany., Rupp H; Center for Sepsis Control and Care, Jena University Hospital, Am Klinikum 1, 07747 Jena, Germany; Section Translational Neuroimmunology, Department of Neurology, Jena University Hospital, Am Klinikum 1, 07747 Jena, Germany., Chung HY; Center for Sepsis Control and Care, Jena University Hospital, Am Klinikum 1, 07747 Jena, Germany; Section Translational Neuroimmunology, Department of Neurology, Jena University Hospital, Am Klinikum 1, 07747 Jena, Germany., Haselmann H; Center for Sepsis Control and Care, Jena University Hospital, Am Klinikum 1, 07747 Jena, Germany; Section Translational Neuroimmunology, Department of Neurology, Jena University Hospital, Am Klinikum 1, 07747 Jena, Germany., Strauss AS; Section Translational Neuroimmunology, Department of Neurology, Jena University Hospital, Am Klinikum 1, 07747 Jena, Germany., Schmidl L; Section Translational Neuroimmunology, Department of Neurology, Jena University Hospital, Am Klinikum 1, 07747 Jena, Germany., Hempel N; Section Translational Neuroimmunology, Department of Neurology, Jena University Hospital, Am Klinikum 1, 07747 Jena, Germany., Grünewald L; Department of Psychiatry, Psychosomatic Medicine and Psychotherapy, University Hospital of Frankfurt, 60528 Frankfurt, Germany., Urbach A; Department of Neurology, Jena University Hospital, Am Klinikum 1, 07747 Jena, Germany; Jena Center for Healthy Aging, Jena University Hospital, Am Klinikum 1, 07747 Jena, Germany; Leibniz Institute on Aging, Aging Research Center Jena, Beutenbergstr. 11, 07745 Jena, Germany., Bauer M; Center for Sepsis Control and Care, Jena University Hospital, Am Klinikum 1, 07747 Jena, Germany; Department of Anesthesiology and Intensive Care, Jena University Hospital, Am Klinikum 1, 07747 Jena, Germany., Toyka KV; Department of Neurology, University of Würzburg, 97080 Würzburg, Germany., Blaess M; Center for Sepsis Control and Care, Jena University Hospital, Am Klinikum 1, 07747 Jena, Germany; Institute of Precision Medicine, Medical and Life Sciences Faculty, Furtwangen University, 78054 Villingen-Schwenningen, Germany., Claus RA; Center for Sepsis Control and Care, Jena University Hospital, Am Klinikum 1, 07747 Jena, Germany; Department of Anesthesiology and Intensive Care, Jena University Hospital, Am Klinikum 1, 07747 Jena, Germany., König R; Center for Sepsis Control and Care, Jena University Hospital, Am Klinikum 1, 07747 Jena, Germany; Department of Anesthesiology and Intensive Care, Jena University Hospital, Am Klinikum 1, 07747 Jena, Germany., Geis C; Center for Sepsis Control and Care, Jena University Hospital, Am Klinikum 1, 07747 Jena, Germany; Section Translational Neuroimmunology, Department of Neurology, Jena University Hospital, Am Klinikum 1, 07747 Jena, Germany; German Center for Mental Health (DZP), Center for Intervention and Research on Adaptive and Maladaptive Brain Circuits Underlying Mental Health (C-I-R-C), Jena-Magdeburg-Halle, Jena, Germany. Electronic address: christian.geis@med.uni-jena.de.

المصدر: Molecular therapy : the journal of the American Society of Gene Therapy [Mol Ther] 2024 Jul 03; Vol. 32 (7), pp. 2113-2129. Date of Electronic Publication: 2024 May 23.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 100890581 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1525-0024 (Electronic) Linking ISSN: 15250016 NLM ISO Abbreviation: Mol Ther Subsets: MEDLINE

مواضيع طبية MeSH: Neuronal Plasticity* , Cognitive Dysfunction*/etiology , Cognitive Dysfunction*/metabolism , Cognitive Dysfunction*/therapy , Cognitive Dysfunction*/genetics , Sepsis-Associated Encephalopathy*/metabolism , Sepsis-Associated Encephalopathy*/etiology , Sepsis-Associated Encephalopathy*/therapy , Sepsis-Associated Encephalopathy*/genetics , Hippocampus*/metabolism , Brain-Derived Neurotrophic Factor*/metabolism , Brain-Derived Neurotrophic Factor*/genetics , Disease Models, Animal* , Cytoskeletal Proteins*/genetics , Cytoskeletal Proteins*/metabolism, Animals ; Mice ; Nerve Tissue Proteins/genetics ; Nerve Tissue Proteins/metabolism ; Dependovirus/genetics ; Male ; Long-Term Potentiation ; Receptor, trkB/metabolism ; Receptor, trkB/genetics ; Genetic Vectors/administration & dosage ; Genetic Vectors/genetics ; Synapses/metabolism

المؤلفون: Zhu T; Department of Critical Care Medicine, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, Zhejiang Province 310020, China., Yao Y; Department of Neurology, The Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou, Zhejiang Province 310052, China; Department of Pediatrics, Shaoxing People's Hospital, Shaoxing, Zhejiang Province 312300, China., Ding J; Department of Neurology, The Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou, Zhejiang Province 310052, China; Department of Pediatrics, Yiwu Maternal and Child Health Care Hospital, Yiwu, Zhejiang Province 322000, China., Zhang C; Department of Neurology, The Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou, Zhejiang Province 310052, China., Xia N; Department of Neurology, The Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou, Zhejiang Province 310052, China., Tao Y; Department of Neurology, The Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou, Zhejiang Province 310052, China., Zhang W; Department of Neurology, The Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou, Zhejiang Province 310052, China., Qi H; Department of Neurology, The Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou, Zhejiang Province 310052, China., Gong L; Department of Neurology, The Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou, Zhejiang Province 310052, China. Electronic address: 21918475@zju.edu.cn., Jiang P; Department of Neurology, The Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, Hangzhou, Zhejiang Province 310052, China. Electronic address: jiangpeifang@zju.edu.cn.

المصدر: International immunopharmacology [Int Immunopharmacol] 2024 Sep 30; Vol. 139, pp. 112744. Date of Electronic Publication: 2024 Jul 25.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 100965259 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-1705 (Electronic) Linking ISSN: 15675769 NLM ISO Abbreviation: Int Immunopharmacol Subsets: MEDLINE

مواضيع طبية MeSH: Sepsis-Associated Encephalopathy*/drug therapy , Autophagy*/drug effects , Adenine*/analogs & derivatives , Adenine*/pharmacology , Lipopolysaccharides* , Cognition*/drug effects , Neuroinflammatory Diseases*/drug therapy , Neuroinflammatory Diseases*/immunology, Animals ; Male ; Mice ; Disease Models, Animal ; Mice, Inbred C57BL ; Cytokines/metabolism ; Hippocampus/drug effects ; Hippocampus/metabolism ; Hippocampus/pathology ; Cognitive Dysfunction/drug therapy ; Cognitive Dysfunction/etiology ; Anti-Inflammatory Agents/therapeutic use ; Anti-Inflammatory Agents/pharmacology

المؤلفون: Xu K; Department of Anesthesiology and Hongqiao International Institute of Medicine, Tongren Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200336, China., Huang Q; Department of Neurology, Tongren Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200336, China., Lyu Y; Department of Traditional Chinese Medicine, Tongren Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200336, China., Wang S; Department of Anesthesiology and Hongqiao International Institute of Medicine, Tongren Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200336, China., Lu Y; Department of Anesthesiology and Hongqiao International Institute of Medicine, Tongren Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200336, China. Electronic address: yinzhonglu@shsmu.edu.cn., Qian G; Department of Anesthesiology and Hongqiao International Institute of Medicine, Tongren Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200336, China; Shanghai Changning Maternity and Infant Health Hospital, Shanghai 200050, China. Electronic address: drqiantr@sjtu.edu.cn.

المصدر: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2024 Sep; Vol. 178, pp. 117200. Date of Electronic Publication: 2024 Jul 24.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 8213295 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1950-6007 (Electronic) Linking ISSN: 07533322 NLM ISO Abbreviation: Biomed Pharmacother Subsets: MEDLINE

مواضيع طبية MeSH: Sepsis-Associated Encephalopathy*/prevention & control , Gastrointestinal Microbiome*/drug effects , Sepsis*/complications , Sepsis*/microbiology , Phosphatidylserines*/metabolism , Phosphatidylserines*/pharmacology , Mice, Inbred C57BL*, Animals ; Male ; Mice ; Aging ; Lipopolysaccharides ; Cytokines/metabolism ; Disease Models, Animal ; Hippocampus/drug effects ; Hippocampus/metabolism ; Hippocampus/pathology ; Signal Transduction/drug effects