المؤلفون: Elise Pierson, Marie Haufroid, Tannu Priya Gosain, Pankaj Chopra, Ramandeep Singh, Johan Wouters

المصدر: Molecules, Vol 25, Iss 2, p 415 (2020)

مصطلحات موضوعية: m. tuberculosis, phosphoserine phosphatase, serb2, 2,7,9-trisubstituted harmine derivatives, Organic chemistry, QD241-441

وصف الملف: electronic resource

Relation: https://www.mdpi.com/1420-3049/25/2/415; https://doaj.org/toc/1420-3049

URL الوصول: https://doaj.org/article/7d9a98c7192040c7be2a22039d12ab06

المؤلفون: Marie Haufroid, Johan Wouters

المصدر: Pharmaceuticals, Vol 12, Iss 2, p 66 (2019)

مصطلحات موضوعية: SerB2, phosphoserine phosphatase, HAD, tuberculosis, SerA1, SerC, phosphoserine aminotransferase, phosphoglycerate dehydrogenase, Medicine, Pharmacy and materia medica, RS1-441

وصف الملف: electronic resource

Relation: https://www.mdpi.com/1424-8247/12/2/66; https://doaj.org/toc/1424-8247

URL الوصول: https://doaj.org/article/739ce2a4f523482286d5fa3f753de368

المؤلفون: Elise Pierson, Johan Wouters

المصدر: Pierson, E & Wouters, J 2020, ' Biochemical characterization of phosphoserine phosphatase SerB2 from Mycobacterium marinum ', Biochemical and Biophysical Research Communications, vol. 530, no. 4, pp. 739-744 . https://doi.org/10.1016/j.bbrc.2020.07.017

مصطلحات موضوعية: Models, Molecular, 0301 basic medicine, Protein Conformation, Phosphatase, Biophysics, Mycobacterium Infections, Nontuberculous, Biochemistry, Substrate Specificity, Dephosphorylation, Serine, Phosphoserine, 03 medical and health sciences, 0302 clinical medicine, Allosteric Regulation, Bacterial Proteins, clofazimine, Humans, Amino Acid Sequence, Enzyme kinetics, Molecular Biology, Mycobacterium marinum, chemistry.chemical_classification, biology, Chemistry, SerB2, Active site, Phosphoserine phosphatase, Mycobacterium tuberculosis, Cell Biology, biology.organism_classification, Harmine derivatives, Phosphoric Monoester Hydrolases, 030104 developmental biology, Enzyme, HAD phosphatases, 030220 oncology & carcinogenesis, biology.protein, Protein Multimerization

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5545e262a29f23764712d3373861eadb
https://doi.org/10.1016/j.bbrc.2020.07.017

المؤلفون: Elise, Pierson, Marie, Haufroid, Tannu Priya, Gosain, Pankaj, Chopra, Ramandeep, Singh, Johan, Wouters

المصدر: Molecules

مصطلحات موضوعية: Antitubercular Agents, Drug Evaluation, Preclinical, Drug Repositioning, SerB2, Microbial Sensitivity Tests, Mycobacterium tuberculosis, Phosphoric Monoester Hydrolases, Article, Molecular Docking Simulation, phosphoserine phosphatase, Harmine, Kinetics, M. tuberculosis, Thermodynamics, 2,7,9-trisubstituted harmine derivatives, Enzyme Inhibitors

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::203972e16b62de65b1e96f4ee97d311f
https://pubmed.ncbi.nlm.nih.gov/31963843

المؤلفون: Marie Haufroid, Johan Wouters

المصدر: Haufroid, M & Wouters, J 2019, ' Targeting the serine pathway : a promising approach against tuberculosis? ', Pharmaceuticals, vol. 12, no. 2, 66 . https://doi.org/10.3390/ph12020066
Pharmaceuticals
Pharmaceuticals, Vol 12, Iss 2, p 66 (2019)

مصطلحات موضوعية: 0301 basic medicine, Opinion, phosphoserine aminotransferase, Tuberculosis, Pharmaceutical Science, lcsh:Medicine, lcsh:RS1-441, SerA1, Sequence alignment, Computational biology, Selective inhibition, Serine, lcsh:Pharmacy and materia medica, phosphoserine phosphatase, 03 medical and health sciences, Drug Discovery, Medicine, Phosphoglycerate dehydrogenase, chemistry.chemical_classification, 030102 biochemistry & molecular biology, business.industry, Drug discovery, lcsh:R, HAD, SerB2, phosphoglycerate dehydrogenase, medicine.disease, Clinical trial, 030104 developmental biology, Enzyme, chemistry, tuberculosis, SerC, Molecular Medicine, Phosphoserine aminotransferase, Phosphoserine phosphatase, business, Infectious agent

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec08e8f800b89035911bc56c12f0f073
https://pure.unamur.be/ws/files/40741849/pharmaceuticals_12_00066_v3.pdf

المؤلفون: Ramandeep Singh, Elise Pierson, Tannu Priya Gosain, Pankaj Chopra, Marie Haufroid, Johan Wouters

المصدر: Molecules
Volume 25
Issue 2
Pierson, E, Haufroid, M, Gosain, T P, Chopra, P, Singh, R & Wouters, J 2020, ' Identification and Repurposing of Trisubstituted Harmine Derivatives as Novel Inhibitors of Mycobacterium tuberculosis Phosphoserine Phosphatase ', Molecules, vol. 25, no. 2, 415 . https://doi.org/10.3390/molecules25020415
Molecules, Vol 25, Iss 2, p 415 (2020)

مصطلحات موضوعية: Phosphatase, Pharmaceutical Science, Analytical Chemistry, lcsh:QD241-441, phosphoserine phosphatase, Mycobacterium tuberculosis, Serine, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Harmine, lcsh:Organic chemistry, M. tuberculosis, Drug Discovery, Structure–activity relationship, 2,7,9-trisubstituted harmine derivatives, Physical and Theoretical Chemistry, 030304 developmental biology, chemistry.chemical_classification, 0303 health sciences, biology, Chemistry, Organic Chemistry, SerB2, Phosphoserine phosphatase, biology.organism_classification, Enzyme, Biochemistry, Chemistry (miscellaneous), Docking (molecular), 030220 oncology & carcinogenesis, 9-trisubstituted harmine derivatives, Molecular Medicine

وصف الملف: application/pdf; image/png

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7808814977afd98e80c6c684b4e455f7
https://doi.org/10.3390/molecules25020415

لا يتم عرض هذه النتيجة على الضيوف.
تسجيل الدخول للوصول الكامل.

لا يتم عرض هذه النتيجة على الضيوف.
تسجيل الدخول للوصول الكامل.

لا يتم عرض هذه النتيجة على الضيوف.
تسجيل الدخول للوصول الكامل.